{"title":"Symptomatic SARS-CoV2 infections in patients treated in France by hemodialysis in an establishment, or at home or by peritoneal dialysis: Data from the REIN and RDPLF registry","authors":"C. Couchoud, C. Verger","doi":"10.25796/bdd.v3i4.59643","DOIUrl":"https://doi.org/10.25796/bdd.v3i4.59643","url":null,"abstract":"In France all patients treated with dialysis are registered in the REIN registry (Epidemiology and Information Network in Nephrology) ; in addition the RDPLF (French Language Peritoneal Dialysis Registry) monitors patients treated at home in French-speaking regions and countries. \u0000Asymptomatic patients with a positive SARS-CoV2 test were excluded : the study focused only on patients with symptomatic COVID-19 disease. Data from REIN and RDPLF were used. In total, 3,541 patients were declared symptomatic with COVID-19. The proportion of patients with symptomatic SAR-coV2 infection was 4.9% in patients treated at home by peritoneal dialysis or hemodialysis and 8.0% in those treated in a dialysis unit. After adjustment for age and comorbidities, being treated at home was associated with a higher risk of mortality. In conclusion, home treatments could represent a solution for preventing the risk of contamination during the circulation of the virus. On the other hand, the risk of mortality in symptomatic patients at home could be linked to a delay in treatment: rigorous remote organization must be implemented so as not to delay the treatment of patients in the event of infection.","PeriodicalId":366938,"journal":{"name":"Bulletin de la Dialyse à Domicile","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124246908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"First reported case of peritoneal dialysis infection with lactobacillus gasseri: when the body’s friend turns against its host","authors":"Jamil El Moutaouakil, A. Pardon, V. Caudwell","doi":"10.25796/bdd.v3i4.59533","DOIUrl":"https://doi.org/10.25796/bdd.v3i4.59533","url":null,"abstract":"Summary \u0000We report a case of lactobacillus gasseri peritonitis in a patient treated by peritoneal dialysis. \u0000Streptococcus anginus and lactobacillus gasseri bacteria are commensal organisms of human oral, small intestinal, colic and vaginal mucous membranes. An infection with streptococcus anginosus during peritoneal dialysis, one responsible for an intra-abdominal abscess, has already been described, this type of streptococcus being widely associated with abscess formation. In contrast, no case of peritoneal infection with lactobacillus gasseri has ever been described. This bacterium is native to the mucous membranes, and colonizes the digestive tract of infants during childbirth, as they pass through the vaginal canal. It has local adaptation capacities, namely tolerance to acid pH, adhesion to the mucous membrane and resistance to bile salts. It is recognized as having an antimicrobial and probiotic function due to its production of bacteriocin, its local immunomodulatory role, its attenuation of the development of helicobacter pylori, its positive effect on the balance of the vaginal flora and its improvement of infectious diarrhea. This usually makes it an ally that contributes to our systemic balance but its irruption in the peritoneum has made it a pathogenic bacterium. The treatment of this peritoneal infection required a classic duration of treatment of organisms of digestive origin, i.e. 3 weeks","PeriodicalId":366938,"journal":{"name":"Bulletin de la Dialyse à Domicile","volume":"51 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115988576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. Verger, M. Dratwa, P. Durand, J. Chanliau, É. Goffin, T. Petitclerc, B. Issad, G. Veniez, I. Vernier, F. Touré, C. Courivaud
{"title":"Assessment of the interest of an open-access French-language journal specializing in home dialysis","authors":"C. Verger, M. Dratwa, P. Durand, J. Chanliau, É. Goffin, T. Petitclerc, B. Issad, G. Veniez, I. Vernier, F. Touré, C. Courivaud","doi":"10.25796/bdd.v3i4.58833","DOIUrl":"https://doi.org/10.25796/bdd.v3i4.58833","url":null,"abstract":"The Bulletin de la dialyse à Domicile (Home Dialysis Bulletin) is a quaterly open access journal, created in June 2018. It adheres to international standards of ethics and good practices in medical publishing; it is indexed in the directory of open access journals (doaj.org). The aim of this work was, by means of an anonymous online survey, to assess its appreciation among French-speaking nephrologists and healthcare teams. The analysis of the responses to the survey highlighted a high degree of appreciation by readers, the importance of using their native language which abrogates language barriers to their easy access to medical or nursing information, the need for practical articles but also recommendations, the sharing of clinical cases. Readers believe that the Bulletin de la Dialyse à Domicile provides them with a source of information to which they have little or no access elsewhere. It responds to a clearly expressed need for all those who take care of patients treated by home dialysis, but remains closely linked to English speakers because its the bi-lingual online publication which give the opportunity to accept foreign submissions and share experience between countries.","PeriodicalId":366938,"journal":{"name":"Bulletin de la Dialyse à Domicile","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126324394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Transition between peritoneal dialysis and home hemodialysis in Belgium and France in the RDPLF","authors":"C. Verger, E. Fabre","doi":"10.25796/BDD.V3I3.58393","DOIUrl":"https://doi.org/10.25796/BDD.V3I3.58393","url":null,"abstract":"A renewed interest in home hemodialysis has emerged in recent years, favored by the availability of new dialysis machines and encouraging publication about daily hemodialysis. Since 2013, the RDPLF has become a home dialysis registry that records the data of patients treated with peritoneal dialysis and those treated with home hemodialysis, all techniques combined. Nine Belgian centers and fifty seven French centers communicate information about their patients treated by hemodialysis at home. In the RDPLF centers, 56% of Belgian home hemodialysis patients are treated with daily hemodialysis, in France 83% of home patients are on daily dialysis. This French difference however is not representative of the whole country but can be explained through recruitment of new centers already involved in peritoneal dialysis and convinced by the interest of continuaous daily treatment. In both countries, 13% of home hemodialysis patients have been previously treated with peritoneal dialysis with an interim period of in-center hemodialysis or transplantation. The median duration of in center hemodialysis is 10 months with extremes ranging from 2 months to 25 years. PD patients treated secondarily in home hemodialysis are mainly young, non-diabetic and independent patients. Early information in patients who have a risk of peritoneal dialysis failure, and the provision of materials allowing both techniques would reduce or abolish a transient transfer to in center hemodialysis and would ensure home care in patients who prefer.","PeriodicalId":366938,"journal":{"name":"Bulletin de la Dialyse à Domicile","volume":"87 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127652315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Sánchez-Álvarez, M. A. Bajo Rubio, V. Paraíso Cuevas, V. López de la Manzanara, Rosario Llópez Carratala, D. Rodríguez Puyol, Hernando Trujillo Cuéllar, J. Grande Villoria, Luz Maria Cuiña Barja
{"title":"Impact of SARS-CoV-2 infection in the population on peritoneal dialysis. The Spanish experience : preliminary results.","authors":"E. Sánchez-Álvarez, M. A. Bajo Rubio, V. Paraíso Cuevas, V. López de la Manzanara, Rosario Llópez Carratala, D. Rodríguez Puyol, Hernando Trujillo Cuéllar, J. Grande Villoria, Luz Maria Cuiña Barja","doi":"10.25796/bdd.v3i3.57873","DOIUrl":"https://doi.org/10.25796/bdd.v3i3.57873","url":null,"abstract":"The recent appearance of the SARS-CoV-2 pandemic has had a significant impact on the general population. Patients on renal replacement therapy (RRT) have not been unaware of this situation, and due to their characteristics, they are especially vulnerable. We present the results of the analysis of the COVID-19 Registry of the Spanish Society of Nephrology. This online registry began operating on March 18, 2020. It collects epidemiological variables, contagion and diagnosis data, signs and symptoms, treatments, and outcomes. Patients were diagnosed with SARS-CoV-2 infection based on the results of the PCR of the virus, carried out both in patients who had manifested compatible symptoms or had suspicious signs and in those who had undergone screening after contact with another patient. \u0000As of July 18, the registry had data on 1748 patients, from all the autonomous communities. The most represented form of RRT is in-center hemodialysis (HDC), followed by transplant patients. Only 55 (4%) were on peritoneal dialysis (PD). PD patients’ symptoms are similar to those of the general population. A very high percentage (93%) required hospital admission, but none in intensive care units. The most used treatments were hydroxychloroquine, lopinavir–ritonavir, and steroids. Mortality is high and reaches 18%. Age and pneumonia were independently associated with the risk of death. We also found a beneficial effect of PD over HDC. \u0000As conclusions, SARS-CoV-2 infection already affects a significant number of Spanish patients on RRT, mainly those on HDC. The proportion of infected patients on PD is significantly lower. Hospitalization rates are very high, and mortality is high; age and the development of pneumonia are factors associated with mortality, while those on PD had lower mortality.","PeriodicalId":366938,"journal":{"name":"Bulletin de la Dialyse à Domicile","volume":"77 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122066015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of a new rapid-diagnostic test for peritonitis in peritoneal dialysis: the PERIPLEX® device.","authors":"P. Durand, C. Verger","doi":"10.25796/bdd.v3i4.57953","DOIUrl":"https://doi.org/10.25796/bdd.v3i4.57953","url":null,"abstract":"In 2017, the British company MOLOGIC developed a new rapid-diagnostic test (PERIPLEX®) for the diagnosis of peritonitis in patients undergoing peritoneal dialysis. This single-use test is based on the detection in dialysate of two biomarkers of bacterial infection: Interleukin-6 (IL-6) and matrix metalloproteinase-8 (MMP-8). The test was evaluated in a prospective multicenter study including 10 centers from the RDPLF (French Language Peritoneal Dialysis Registry). A total of 184 tests were performed; 86 tests were negative and 98 were positive. 85 peritonitis were confirmed. There were no false-negatives, and 13 false-positives. Of the 13 false-positives, 7 of them were for sepsis without peritonitis, or peritoneal inflammation. The performance of the test is considered excellent: sensitivity 100%, specificity 86.9%, positive predictive value 86.7%, negative predictive value 100%. In this study, a negative test can formally rule out the diagnosis of peritonitis.","PeriodicalId":366938,"journal":{"name":"Bulletin de la Dialyse à Domicile","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121608208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Peritoneal dialysis in a Moroccan center: Prevalence and complications","authors":"A. Bahadi, S. Benbria, Hicham Rafik, D. el kabbaj","doi":"10.25796/bdd.v3i2.54793","DOIUrl":"https://doi.org/10.25796/bdd.v3i2.54793","url":null,"abstract":"Abstract : \u0000Introduction: Peritoneal dialysis (PD) is as effective as hemodialysis and often provides a better quality of life for patients. Despite this, the replacement therapy remains little established in our country with a prevalence of less than 1% of patients with end-stage renal disease. The objective of this work is to report the development and complications of PD in our center. \u0000Patients and methods: This is a retrospective study including all patients on PD between October 2008 and March 2019. We noted their demographic and clinical data at their initiation in peritoneal dialysis and we followed their evolution to discuss infectious and mechanical complications as well as the causes of PD exit. \u0000Results: During the study period, 456 patients were admitted for end-stage renal disease. Among these patients, only 28 (6.1%) were put on PD including two diabetics. Their average age was 37.7 years with a sex ratio of 0.8. The average body surface area was 1.59 m² with an average residual renal function of 6.05 ml / min. PD was chosen as the first intention in 20 patients while 8 patients were on hemodialysis. The evolution was marked by a median survival of the technique of 18.5 months characterized by 8 episodes of peritonitis in 4 patients corresponding to a rate of 1 episode over 56 months. Regarding mechanical complications, we noted 9 omentum aspirations, 1 leak in one case and 1 umbilical hernia requiring surgical recovery in a patient. Out of 28 patients, 17 discharges were identified; 10 patients (67%) were transferred to hemodialysis, 4 died and only 3 patients (18%) were transplanted. The final transfer to hemodialysis was related to mechanical complications in 5 cases, loss of ultrafiltration in one case, repeated hydro-sodium overload in one case, peritonitis in one case and social reasons in two cases. \u0000Conclusion: PD is an effective technique which preserves residual renal function and quality of life but its prevalence remains low in the order of 6% of patients treated for end-stage renal disease. The complications are dominated in our context by the mechanical complications main cause of final transfer in hemodialysis.","PeriodicalId":366938,"journal":{"name":"Bulletin de la Dialyse à Domicile","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122312109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Julie Morinière Beaume, C. Nodimar, G. Seret, L. Vrigneaud, S. Bataille, O. Carceles, M. Gosselin, F. Lavainne
{"title":"Revue de presse club des jeunes néphrologues (CJN) : 1e trimestre 2021 de la Dialyse à Domicile","authors":"Julie Morinière Beaume, C. Nodimar, G. Seret, L. Vrigneaud, S. Bataille, O. Carceles, M. Gosselin, F. Lavainne","doi":"10.25796/BDD.V2I4.52333","DOIUrl":"https://doi.org/10.25796/BDD.V2I4.52333","url":null,"abstract":"Introduction (NDLR) \u0000Un groupe de néphrologues issus du Club des jeunes Néphrologues (https://www.cjnephro.com/)sélectionne chaque mois à tour de rôle un article de la littérature internationale en rapport avec la dialyse à domicile, Dialyse Péritonéale ou Hémodialyse à Domicile, et en propose un résumé en français et son analyse. Ces résumés sont également librement téléchargeables sur le site du RDPLF à l’adresse :https://www.rdplf.org/biblio.html. Depuis décembre 2018 ceux sélectionnés au cours du trimestre par ces néphrologues sont publiés sous leur nom dans la présente rubrique du Bulletin de la Dialyse à Domicile.","PeriodicalId":366938,"journal":{"name":"Bulletin de la Dialyse à Domicile","volume":"147 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132720670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Lima, J. Tavares, Nicole Pestana, M. Carvalho, A. Cabrita, A. Rodrigues
{"title":"Sodium removal in peritoneal dialysis: is there room for a new parameter in dialysis adequacy?","authors":"A. Lima, J. Tavares, Nicole Pestana, M. Carvalho, A. Cabrita, A. Rodrigues","doi":"10.25796/BDD.V2I3.21343","DOIUrl":"https://doi.org/10.25796/BDD.V2I3.21343","url":null,"abstract":"In peritoneal dialysis (PD) (as well as in hemodialysis) small solute clearance measured as Kt/v urea has long been used as a surrogate of dialysis adequacy. A better urea clearance was initially thought to increase survival in dialysis patients (as shown in the CANUSA trial)(1), but reanalysis of the data showed a superior contribution of residual renal function as a predictor of patient survival. Two randomized controlled trials (RCT)(2, 3) supported this observation, demonstrating no survival benefit in patients with higher achieved Kt/v. Then guidelines were revised and a minimum Kt/v of 1,7/week was recommended but little emphasis was given to additional parameters of dialysis adequacy. As such, volume overload and sodium removal have gained major attention, since their optimization has been associated with decreased mortality in PD patients(4, 5). Inadequate sodium removal is associated with fluid overload which leads to ventricular hypertrophy and increased cardiovascular mortality(6). Individualized prescription is key for optimal sodium removal as there are differences between PD techniques (CAPD versus APD) and new strategies for sodium removal have emerged (low sodium solutions and adapted PD). In conclusion, future guidelines should address parameters associated with increased survival outcomes (sodium removal playing an important role) and abandon the current one fit all prescription model.","PeriodicalId":366938,"journal":{"name":"Bulletin de la Dialyse à Domicile","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128913409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. Nodimar, G. Seret, L. Vrigneaud, S. Bataille, O. Carceles, M. Gosselin, A. Lanot, F. Lavainne, Julie Morinière Beaume
{"title":"Revue de presse des jeunes néphrologues : 3e trimestre 2019 de la Dialyse à Domicile","authors":"C. Nodimar, G. Seret, L. Vrigneaud, S. Bataille, O. Carceles, M. Gosselin, A. Lanot, F. Lavainne, Julie Morinière Beaume","doi":"10.25796/bdd.v2i3.22123","DOIUrl":"https://doi.org/10.25796/bdd.v2i3.22123","url":null,"abstract":"Un groupe de néphrologues issus du Club des jeunes Néphrologues sélectionne chaque mois à tour de rôle un article de la littérature internationale en rapport avec la dialyse à domicile, Dialyse Péritonéale ou Hémodialyse à Domicile, et en propose un résumé en français et son analyse. Ces résumés sont librement téléchargeables sur le site du RDPLF à l’adresse : https://www.rdplf.org/biblio.html. Depuis décembre 2018 ceux sélectionnés au cours du trimestre par ces néphrologues sont publiés sous leur nom dans la présente rubrique du Bulletin de la Dialyse à Domicile.","PeriodicalId":366938,"journal":{"name":"Bulletin de la Dialyse à Domicile","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114720832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}