IEEE Transactions on Molecular, Biological, and Multi-Scale Communications最新文献_第3页

An Acoustic Communication Model in Plants 植物的声通信模型

IF 2.5

IEEE Transactions on Molecular, Biological, and Multi-Scale Communications Pub Date : 2026-01-01 Epub Date: 2026-07-27 DOI: 10.1109/TMBMC.2026.3717168

Fatih Merdan;Ozgur B. Akan

{"title":"An Acoustic Communication Model in Plants","authors":"Fatih Merdan;Ozgur B. Akan","doi":"10.1109/TMBMC.2026.3717168","DOIUrl":"https://doi.org/10.1109/TMBMC.2026.3717168","url":null,"abstract":"Molecular communication (MC) studies biological signals that are found in nature. Most MC literature focuses on particle properties, even though many natural phenomena exhibit wave-like behavior. One such signal is sound waves. Understanding how sound waves are used in nature can help us better utilize this signal in our interactions with our environment. To take a step in this direction, in this paper, we examine how plants process incoming sound waves and take informed actions. Indeed, plants respond to sound, yet no quantitative communication-theoretic model currently explains this behavior. This study develops the first end-to-end acoustic communication framework for plants. The model is formed following the biological steps of the incoming signal, and a mathematical description is constructed at each step following basic biological models. The resulting end-to-end communication-theoretic model is analyzed using MATLAB. Simulations show that a <inline-formula> <tex-math>$200~Hz$ </tex-math></inline-formula>, <inline-formula> <tex-math>$20~ mu Pa$ </tex-math></inline-formula> stimulus elevates cytosolic <inline-formula> <tex-math>$Ca^{2+}$ </tex-math></inline-formula> from <inline-formula> <tex-math>$150~nM$ </tex-math></inline-formula> to <inline-formula> <tex-math>$230 pm 10~nM$ </tex-math></inline-formula> within 50 seconds which can cause root bending in plants in the long run. This work establishes quantitative phytoacoustics, enabling bio-inspired acoustic connections for precision agriculture and plant signaling research.","PeriodicalId":36530,"journal":{"name":"IEEE Transactions on Molecular, Biological, and Multi-Scale Communications","volume":"12 ","pages":"777-788"},"PeriodicalIF":2.5,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148747293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Transmission Enhancement Scheme of Ca2+ Signaling for Molecular Communications 分子通信中Ca2+信号的传输增强方案

IF 2.3

IEEE Transactions on Molecular, Biological, and Multi-Scale Communications Pub Date : 2026-01-01 Epub Date: 2026-03-12 DOI: 10.1109/TMBMC.2026.3692189

Peng He;Chao Wang;Yaping Cui;Dapeng Wu;Ruyan Wang;Mengnan Su;Yifan Chen

{"title":"A Transmission Enhancement Scheme of Ca2+ Signaling for Molecular Communications","authors":"Peng He;Chao Wang;Yaping Cui;Dapeng Wu;Ruyan Wang;Mengnan Su;Yifan Chen","doi":"10.1109/TMBMC.2026.3692189","DOIUrl":"https://doi.org/10.1109/TMBMC.2026.3692189","url":null,"abstract":"As one of the core signal carriers in molecular communication (MC), Ca2+ exhibits irreplaceable value in nanomedical scenarios, including targeted drug delivery and target detection. However, the random movement of cells and the spatiotemporal attenuation of signals severely limit communication performance. To address these challenges, a Ca2+ signal transmission enhancement model is proposed by integrating cell chemotaxis with a relay amplification mechanism. Specifically, Geometric Brownian Motion (GBM) is employed to quantitatively characterize the movement behavior of biological cells, while relay nanomachines dynamically boost the Ca2+ concentration of passing cells to mitigate signal attenuation. A novel performance metric is developed, and an improved Yin-Yang-Pair Optimization (YYPO) algorithm is adopted to optimize the relay position and energy configuration, thereby maximizing the system performance under the constraint of avoiding cell apoptosis. Simulation results demonstrate that the proposed model achieves a 200% improvement in signal transmission distance compared with the random motion model and an 8% enhancement relative to the pure chemotaxis model. Additionally, the number of activated cells in the target region is increased by 43% compared with the random model. This work provides an efficient and compatible signal transmission solution for the construction of an in vivo nano-internet of things.","PeriodicalId":36530,"journal":{"name":"IEEE Transactions on Molecular, Biological, and Multi-Scale Communications","volume":"12 ","pages":"552-562"},"PeriodicalIF":2.3,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148003416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Frame-Structured DNA-Based Molecular Communication for Reliable Internet of Bio-Nano Things 基于框架结构dna的可靠生物纳米物联网分子通信

IF 2.3

IEEE Transactions on Molecular, Biological, and Multi-Scale Communications Pub Date : 2026-01-01 Epub Date: 2026-03-26 DOI: 10.1109/TMBMC.2026.3697133

Jinyan Fu;Quanhong Yu;Wanli Cheng;Yifan Chen;Kun Yang;Yue Sun

{"title":"Frame-Structured DNA-Based Molecular Communication for Reliable Internet of Bio-Nano Things","authors":"Jinyan Fu;Quanhong Yu;Wanli Cheng;Yifan Chen;Kun Yang;Yue Sun","doi":"10.1109/TMBMC.2026.3697133","DOIUrl":"https://doi.org/10.1109/TMBMC.2026.3697133","url":null,"abstract":"Molecular communication (MC) employs biochemical molecules to enable biocompatible and low-power signaling at the nanoscale. Among diverse molecular carriers, DNA offers exceptional advantages in information density, biochemical stability, and programmable synthesis, making it particularly suitable for Internet of Bio-Nano Things (IoBNT) networks. However, most DNA-MC studies have been limited to physical-layer modeling, and the data link layer still lacks a well-defined framework for reliable, high-throughput communication. To bridge this gap, this paper proposes a structured frame architecture for track-hopper-based DNA-MC (THMC) with externally guided transport that integrates synchronization, addressing, sequencing, indexing, and error-correction modules optimized through Yin-Yang Coding (YYC) and Reed–Solomon (RS) schemes. The frame structure serves as a data-link-layer design for reliable frame organization and delivery under THMC transport. A channel propagation model based on the Fokker–Planck equation and the inverse Gaussian distribution is adopted to connect physical channel parameters to communication performance trends. Simulation results demonstrate a peak frame utilization efficiency of 68.9% and confirm that the structured frame design achieves a favorable trade-off between protocol overhead and link-layer reliability, outperforming unstructured baseline schemes in synchronization robustness, loss detection, and ordered reassembly under varying channel conditions. The proposed framework provides frame-structured data-link-layer design for THMC, serving as a foundation for reliable and scalable IoBNT communication.","PeriodicalId":36530,"journal":{"name":"IEEE Transactions on Molecular, Biological, and Multi-Scale Communications","volume":"12 ","pages":"662-673"},"PeriodicalIF":2.3,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148171569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Cylindrical Nanowire Array-Based Flexure-FET Receiver for Molecular Communication 用于分子通信的圆柱形纳米线阵列弯曲场效应晶体管接收器

IF 2.3

IEEE Transactions on Molecular, Biological, and Multi-Scale Communications Pub Date : 2026-01-01 Epub Date: 2026-03-06 DOI: 10.1109/TMBMC.2026.3671270

Dilara Aktas;Ozgur B. Akan

{"title":"A Cylindrical Nanowire Array-Based Flexure-FET Receiver for Molecular Communication","authors":"Dilara Aktas;Ozgur B. Akan","doi":"10.1109/TMBMC.2026.3671270","DOIUrl":"https://doi.org/10.1109/TMBMC.2026.3671270","url":null,"abstract":"Molecular communication (MC) enables biocompatible and energy-efficient information transfer through chemical signaling, forming a foundational paradigm for emerging applications in the Internet of Nano Things (IoNT) and intrabody healthcare systems. The realization of this vision critically depends on developing advanced receiver architectures that merge nanoscale communication and networking techniques with bio-cyber interfaces, ensuring energy-efficient, reliable, and low-complexity modulation and detection while maintaining biocompatibility. To address these challenges, the Flexure-FET (flexure sensitive field-effect transistor) MC receiver was introduced as a mechanically transducing design capable of detecting both charged and neutral molecular species. In this study, we present a cylindrical nanowire array–based Flexure-FET MC receiver that enhances design versatility and scalability through distributed electromechanical coupling in a suspended-gate configuration. The proposed array architecture offers additional geometric degrees of freedom, including nanowire radius, length, spacing, and array size, providing a flexible framework that can be tailored to advanced MC scenarios. An analytical end-to-end model is developed to characterize the system’s electromechanical response, noise behavior, and information-theoretic performance, including signal-to-noise ratio (SNR) and channel capacity. The results reveal the strong interdependence between geometry, electromechanical dynamics, and molecular binding processes, enabling tunable control over sensitivity, noise characteristics, and communication capacity. The enhanced structural tunability and array configuration of the proposed design provide a flexible foundation for future mixture-based and spatially modulated MC systems, paving the way toward scalable and multifunctional receiver architectures within the IoNT framework.","PeriodicalId":36530,"journal":{"name":"IEEE Transactions on Molecular, Biological, and Multi-Scale Communications","volume":"12 ","pages":"412-421"},"PeriodicalIF":2.3,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147557753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Guest Editorial Special Feature on Quantum Biology: Series III 量子生物学特邀评论：系列三

IF 2.5

IEEE Transactions on Molecular, Biological, and Multi-Scale Communications Pub Date : 2026-01-01 Epub Date: 2026-02-24 DOI: 10.1109/TMBMC.2026.3661331

Harun Šiljak

引用次数: 0

Molecular Communication for Gastroretentive Drug Delivery 胃保留性药物传递的分子通讯

IF 2.3

IEEE Transactions on Molecular, Biological, and Multi-Scale Communications Pub Date : 2026-01-01 Epub Date: 2026-03-09 DOI: 10.1109/TMBMC.2026.3671196

Sebastian Lotter;Marco Seiter;Maryam Pirmoradi;Lukas Brand;Dagmar Fischer;Robert Schober

引用次数: 0

Physics of SPION–Surface Interactions in Fluidic Channels: Implications for Molecular Communication Systems 流体通道中自旋子-表面相互作用的物理学：对分子通信系统的影响

IF 2.3

IEEE Transactions on Molecular, Biological, and Multi-Scale Communications Pub Date : 2026-01-01 Epub Date: 2026-04-21 DOI: 10.1109/TMBMC.2026.3686303

Keyu Xiao;Angelika S. Thalmayer;Jens Kirchner;Georg Fischer

引用次数: 0

Information Transmission in Quorum Sensing for Gut Microbiome 肠道微生物群体感应中的信息传递

IF 2.3

IEEE Transactions on Molecular, Biological, and Multi-Scale Communications Pub Date : 2026-01-01 Epub Date: 2026-03-24 DOI: 10.1109/TMBMC.2026.3677248

O. Tansel Baydas;Efe Yatgin;Ozgur B. Akan

引用次数: 0

The Potential of Spatially Detecting SPIONs Using Multiple Sensor Coils 多传感器线圈空间探测SPIONs的潜力

IF 2.5

IEEE Transactions on Molecular, Biological, and Multi-Scale Communications Pub Date : 2026-01-01 Epub Date: 2026-08-05 DOI: 10.1109/TMBMC.2026.3720580

Paul Wolff;Luiz C. P. Wille;Stefan Lyer;Jens Kirchner

{"title":"The Potential of Spatially Detecting SPIONs Using Multiple Sensor Coils","authors":"Paul Wolff;Luiz C. P. Wille;Stefan Lyer;Jens Kirchner","doi":"10.1109/TMBMC.2026.3720580","DOIUrl":"https://doi.org/10.1109/TMBMC.2026.3720580","url":null,"abstract":"Detecting magnetic nanoparticles with inductive sensor coils is a proven, feasible and cost-efficient method. Recently, molecular communication in fluids, primarily vascular system models, has been investigated. The one-sensor approach is useful for determining the presence of superparamagnetic iron-oxide nanoparticles (SPIONs) in the vicinity of the sensor. However, distinguishing between a small number of particles close to the sensor and a greater number further away remains problematic. To solve this, spatial detection using multiple sensors is investigated. This opens up the possibility of utilizing spatial information in a communication context, as well as enabling imaging options that display the particle distribution over the cross-sectional area of the channel. In consequence, the concentration can be determined with greater precision. The stability of the sensors is investigated, proving the reliability of reference scales for the shift to concentration relation. Nonetheless, the presented approach is subject to several limitations and factors that must be considered in future work. To conclude the presented work, it can be said that advances could be achieved in the position and concentration determination of SPIONs, as well as a structured investigation on sensor stability.","PeriodicalId":36530,"journal":{"name":"IEEE Transactions on Molecular, Biological, and Multi-Scale Communications","volume":"12 ","pages":"833-838"},"PeriodicalIF":2.5,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=11643285","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148746830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Density Matters: The Effect of SPION Sedimentation on Molecular Communication 密度问题：SPION沉降对分子通讯的影响

IF 2.5

IEEE Transactions on Molecular, Biological, and Multi-Scale Communications Pub Date : 2026-01-01 Epub Date: 2026-08-05 DOI: 10.1109/TMBMC.2026.3720566

Keyu Xiao;Luiz C. P. Wille;Daniel Fleischhauer;Sebastian Lotter;Stefan Lyer;Dietmar Drummer;Georg Fischer;Jens Kirchner

{"title":"Density Matters: The Effect of SPION Sedimentation on Molecular Communication","authors":"Keyu Xiao;Luiz C. P. Wille;Daniel Fleischhauer;Sebastian Lotter;Stefan Lyer;Dietmar Drummer;Georg Fischer;Jens Kirchner","doi":"10.1109/TMBMC.2026.3720566","DOIUrl":"https://doi.org/10.1109/TMBMC.2026.3720566","url":null,"abstract":"Superparamagnetic iron-oxide nanoparticles (SPIONs) have emerged as promising information carriers in the field of molecular communication (MC). However, a critical discrepancy exists between theoretical models and experimental realities: while theoretical frameworks typically assume neutral buoyancy and neglect gravitational forces, practical implementations exhibit significant gravity-induced sedimentation. This oversight leads to substantial prediction errors and system unreliability. To address this, we developed an experimental testbed featuring a vertically oriented bifurcated channel, specifically designed to isolate and quantify the impact of gravity on signal propagation. Our experimental results empirically demonstrate that sedimentation causes significant deviations in channel impulse response (CIR), contradicting the simplifying assumptions found in existing literature. Furthermore, we elucidate the physical mechanism of sedimentation based on hydrodynamic instability to clarify the factors driving this settling behavior. This work highlights the necessity of incorporating gravitational effects into system modelling to ensure accurate performance assessment in realistic MC environments.","PeriodicalId":36530,"journal":{"name":"IEEE Transactions on Molecular, Biological, and Multi-Scale Communications","volume":"12 ","pages":"875-881"},"PeriodicalIF":2.5,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=11643295","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148780946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0