{"title":"Analysis of the Availability of Botulinum Toxin Type A in the Treatment of Children with Spastic Cerebral Palsy in Ukraine: A Survey of Doctors","authors":"Sabina Auhunas, Alex Wolf, O.V. Kyryk","doi":"10.30841/2786-720x.1.2024.300447","DOIUrl":"https://doi.org/10.30841/2786-720x.1.2024.300447","url":null,"abstract":"In Ukraine, about 100,000 children suffer from nervous system disorders, with cerebral palsy (CP) being the leading cause of childhood disability. The European Registry of Children with Cerebral Palsy emphasizes the urgency of this problem.\u0000The objective: to analyze the supply, availability, and use of Botulinum toxin type A for the treatment of spastic cerebral palsy in children in Ukraine.\u0000Materials and methods. The study was conducted from October 2019 to December 2020, and it included monitoring the supply and availability of medicines, collecting quantitative and qualitative data from various sources, and interviewing 64 doctors.\u0000Results. This research highlights disparities in medicine supply satisfaction across Ukraine, with surveys of doctors indicating varying degrees of effectiveness in regions like Kyiv and Kharkiv compared to challenges in Zhytomyr and the Kyiv region. Key issues include surplus medicines, unethical distribution practices, and systemic inefficiencies such as lack of patient registries and insufficient funding. The findings suggest an urgent need for regulatory reforms, enhanced healthcare logistics, and infrastructure improvements to achieve equitable healthcare access nationwide.\u0000Conclusions. This study highlights significant challenges in delivering Botulinum toxin type A for spastic cerebral palsy in Ukraine, including systemic inefficiencies, funding shortages, and procurement delays. It emphasizes the need for policy reforms, improved communication, and digital information access to ensure equitable and efficient healthcare. Urgent improvements are advocated to address these issues and enhance patient care nationwide.","PeriodicalId":364588,"journal":{"name":"Family medicine. European practices","volume":"10 14","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140410623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Quality of Life of Patients with Hypertensive Disease and Type 2 Diabetes mellitus and Its Parameters Depending on Plasma Catestatin and Relaxin-2 Levels","authors":"O. Pankova, O. Korzh","doi":"10.30841/2786-720x.1.2024.300459","DOIUrl":"https://doi.org/10.30841/2786-720x.1.2024.300459","url":null,"abstract":"The objective: to investigate the impact of hypertensive disease (HD) and concomitant type 2 diabetes mellitus (T2DM) on the quality of life (QOL) of patients using the SF-36 questionnaire and to evaluate the peculiarities of the QOL parameters depending on plasma relaxin-2 (RLN-2) and catestatin (CTS) levels.\u0000Materials and methods. The study was conducted in accordance with the principles of the Declaration of Helsinki. 136 patients took part in the study: 106 patients with HD and 30 healthy volunteers. The patients with HD were divided into two groups. The first group included 55 patients with HD and T2DM, the second group – 51 persons with HD without T2DM.\u0000Each study participant underwent a comprehensive clinical, laboratory and instrumental examinations. All participants filled out quality of life SF-36 questionnaire and the questionary of HD patient. Concentrations of CTS and RLN-2 in blood plasma were determined by enzyme immunoassay method (E4996Hu, BT Lab, Shanghai, China and E-EL-H1582, Elabscience, USA, respectively). All patients filled the home blood pressure monitoring diaries for 31 days.\u0000Statistical data analysis was performed using the SPSS 25.0 statistical program.\u0000Results. The patients with HD had lower parameters of physical and mental components of health compared to healthy volunteers (p<0.005). It was found that the presence of concomitant T2DM leads to even a greater decrease in quality of life indicators than in patients with HD without carbohydrate metabolism disorders (p<0.05). In patients with RLN-2 levels ≥4.69 pg/ml the lower parameters of the physical component of health (p<0.05) and social functioning (p=0.012) were determined. Lower CTS scores are associated with lower QOL scores (p≤0.005). Significant negative correlations were found between average SBP (aSBP) and indicators of physical and mental components of health (p<0.001), while mean DBP had correlations only with general health and total physical component of health (p<0.05).\u0000Conclusions. HD leads to a decreased QOL of patients, which is confirmed by lower scores of the SF-36 questionnaire and established negative correlations between aSBP and QOL parameters. The presence of concomitant T2DM is associated with even a greater decline in physical and mental health components.","PeriodicalId":364588,"journal":{"name":"Family medicine. European practices","volume":"261 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140414395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Contemporary Role of Antinuclear Antibodies in Early Diagnosis of Autoimmune Rheumatic Diseases","authors":"N. P. Kozak, Tatiana Krasnenkova","doi":"10.30841/2786-720x.1.2024.300450","DOIUrl":"https://doi.org/10.30841/2786-720x.1.2024.300450","url":null,"abstract":"Antinuclear antibodies (ANA) in blood serum remain the primary diagnostic screening test for systemic connective tissue diseases.\u0000This article presents recent literature findings concerning the utilization of ANA in clinical practice. Specifically, it focuses on interpreting analysis positivity, identifying clinically significant types of fluorescence, and categorizing ANA patterns according to specific nosologies. Recommendations for using the name HEp-2-IIF instead of ANA and reporting the results of indirect immunofluorescence analysis for antinuclear antibodies on HEp-2 cell substrates are described in a standardized way, presenting immunofluorescence patterns together with the nomenclature of antibodies and informing about the subsequent management of the patient. Changes made to pattern classification to distinguish between competent and expert level patterns and to improve the visual separation between nuclear and cytoplasmic HEp-2 patterns are discussed.\u0000The need for further study of the prevalence and clinical significance of rare ANA patterns, particularly those directed at the mitotic spindle apparatus (NuMA and MSA-2), is emphasized. Prospects for the study and use of autoantibodies against double-stranded DNA not only in diagnosis but also in the treatment of patients with SLE are noted.\u0000It was concluded that there is a need for further clinical research, collection, and arrangement of various models of HEp-2 IIF to facilitate the accurate determination of «criterion level» patterns, increase the possibilities of early diagnosis of rheumatological diseases, and improve the management tactics of patients in this category.","PeriodicalId":364588,"journal":{"name":"Family medicine. European practices","volume":"21 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140413946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"PAP-test: Possibilities and Limitations","authors":"Olha Burka, Tetyana Naritnik","doi":"10.30841/2786-720x.1.2024.300465","DOIUrl":"https://doi.org/10.30841/2786-720x.1.2024.300465","url":null,"abstract":"Cervical cancer (CC) progresses slowly, and the cytological screening increases the likelihood of early detection of precancerous lesions. Cytology of the cervix is one of the primary methods of effective CC diagnosis, which, thanks to early detection and timely treatment, leads to a stable decrease in morbidity and mortality from invasive CC.\u0000The results of many studies have shown that the specificity of the conventional Pap smear test is approximately 80–100%, its sensitivity ranges from 30% to 80%, and the rate of inadequacy of this method is from 5% to 25%.\u0000With traditional smear preparation, only a small percentage of collected cells end up on the slide, while abnormal cells may be discarded and not analyzed. When viewing the slide, cells that have dried and clumped together may interfere with the visualization of atypical cells.\u0000To overcome these limitations, in 1996, as an alternative to the traditional Pap test, liquid cytology was presented – the technology of preparing slides on which the cells are placed in a single layer. This technology outperformed the conventional Pap test with improved fixation, reduced obscuring factors, and standardized cell transfer. In liquid cytology samples are collected by fully immersing the cytobrush in a vial containing a preservative liquid, whereby the cells are preserved and fixed simultaneously, unlike conventional smears where the sample is applied to a glass slide and fixed separately. Today, two main methods of preparation based on liquid cytology are known: ThinPrep and SurePath.\u0000The results of cytology are described according to the Bethesda system. The Bethesda classification is widely accepted because it corresponds to the clinical presentation, reproduces the nature of the lesions, and is therefore treatmentoriented with a desirable follow-up procedure.\u0000The indisputable advantage of the Pap test by liquid cytology is the ability to perform both cytological and molecular studies, in particular HPV, in one sample. This capability facilitated the implementation of a two-step strategy when HPV testing is used as a triage test for ASC-US or low-grade squamous intraepithelial lesion cytology, or when cytology is used to triage HPV-positive women.","PeriodicalId":364588,"journal":{"name":"Family medicine. European practices","volume":"2014 17","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140416227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Balashov, A.O. Mohilnytskyi, L.H. Shevchenko, N.M. Zakharova, S. Turianytsia, M.S. Pasenko, Olesia P. Hulchiy
{"title":"Behavior, Risk Perception and Misinformation Monitoring Tool: Adaptation of the WHO Approach to the Ukrainian Context","authors":"K. Balashov, A.O. Mohilnytskyi, L.H. Shevchenko, N.M. Zakharova, S. Turianytsia, M.S. Pasenko, Olesia P. Hulchiy","doi":"10.30841/2786-720x.1.2024.300452","DOIUrl":"https://doi.org/10.30841/2786-720x.1.2024.300452","url":null,"abstract":"Risk communication is a process aimed at supporting stakeholders in identifying threats, assessing vulnerabilities and promoting collective resilience. According to WHO recommendations, one of the priority directions for improvement of Ukraine’s emergency response capabilities is the forming and/or implementation of a system for collecting and analyzing information on risk perception, behavior and misinformation, problems and fears of society.\u0000The objective: to determine the validity and reliability of the developed Behavior, Risk Perception and Misinformation Monitoring Tool, which was created on the basis of WHO Europe’s Behavioral Insights tool.\u0000Materials and methods. The analyzed cohort of 56 adults living in different regions of Ukraine differ in gender, level of education, and field of activity.\u0000At the initial stage (T1), risk perception, behavior and misinformation were assessed. A repeat survey (T2) was conducted after 17 days to determine the reliability of the proposed Tool.\u0000Results. The Tool demonstrated adequate or high reliability in most of the proposed questions (ICC ≥ 0.6). Some questions that did not meet the established reliability criteria (ISS < 0.4) were excluded from the final version of the questionnaire. The shortened version of the questionnaire contains 131 questions.\u0000Conclusions. Given that in each block of questions, most of them were found to be reliable, and the deletions did not affect the structure and main purpose of the questionnaire, the Behavior, Risk Perception and Misinformation Monitoring Tool has potential for use in health care practice as a means of assessing behavioral risk perception and misinformation of the adult population.\u0000Systemic monitoring of behavioral variables is an important component of building Ukraine’s emergency response capabilities, which becomes especially important in wartime.","PeriodicalId":364588,"journal":{"name":"Family medicine. European practices","volume":"19 23","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140409417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Beyond Joints: Pulmonary Hypertension in Spondyloarthropathies (Literature review)","authors":"S. Smiyan, Bohdan Koshak, A. Bilukha","doi":"10.30841/2786-720x.1.2024.300572","DOIUrl":"https://doi.org/10.30841/2786-720x.1.2024.300572","url":null,"abstract":"Spondyloarthritis (SpA) represents a complex and dynamic spectrum of inflammatory rheumatic diseases. A nuanced understanding of its clinical, genetic, and immunologic aspects is imperative for accurate diagnosis and effective management. The comprehensive literature review reveals a nuanced connection between spondyloarthropathies and pulmonary hypertension (PH), expanding our understanding of these conditions beyond joint pathology. The synthesis of data from various studies provides valuable insights into the complex interplay of factors contributing to the development of PH in individuals with SpA.\u0000The reviewed studies consistently indicate a heightened prevalence of elevated arterial blood pressure in the pulmonary artery among patients with ankylosing spondylitis and psoriatic arthritis. However, the limited research on reactive arthritis and other subtypes necessitates further exploration to determine the prevalence and characteristics of pulmonary hypertension across the entire spectrum of SpA.\u0000The identified gaps in research emphasize the importance of future studies that encompass the entire SpA spectrum, to provide a more complete understanding of the association with PH. It is crucial to consider all pathogenetic mechanisms, including the impact of chronic persistent inflammation, endothelial dysfunction, and other relevant factors. Recognizing the significance of these mechanisms is vital for comprehensive insights into the complex interplay between both pathologies, guiding the development of targeted interventions and enhancing patient care strategies. This discussion serves as a foundation for future research directions and clinical considerations in the evolving landscape of spondyloarthropathies. This comprehensive overview sets the stage for a deeper exploration of the intricate facets of SpA, including its systemic implications and emerging therapeutic strategies.","PeriodicalId":364588,"journal":{"name":"Family medicine. European practices","volume":"39 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140415856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Seliuk, M. Kozachok, Svitlana Bychkova, Mykhailo Naumov, Iryna Yavorska, Maryna Pylypenko, Olha Seliuk
{"title":"Modern Treatment of Dry Post-viral Cough. Focus on Efficiency and Safety","authors":"M. Seliuk, M. Kozachok, Svitlana Bychkova, Mykhailo Naumov, Iryna Yavorska, Maryna Pylypenko, Olha Seliuk","doi":"10.30841/2786-720x.1.2024.300462","DOIUrl":"https://doi.org/10.30841/2786-720x.1.2024.300462","url":null,"abstract":"Cough is the most common symptom of bronchopulmonary diseases, about which patients consult the doctors of both primary and secondary care. Cough can be caused by diseases of the respiratory tract, digestive tract, and cardiovascular diseases. However, cough most often develops during acute respiratory viral infections (ARVI), which disrupts the patient’s normal activities and limits his work capacity. Since most respiratory infections are viral in nature, the use of antibacterial drugs will not only be of no benefit, but will also significantly worsen the patient’s condition.\u0000The objective: to analyze the effectiveness and tolerability of a combined antitussive agent, which includes codeine, thermopsis extract, licorice root and sodium bicarbonate, in the treatment of dry post-viral cough.\u0000Materials and methods. The study included 60 patients with a dry cough that caused by ARVI, namely: 49 (82%) men and 11 (18%) women. The average age of the patients was 46±4.7 years. Most of the subjects (90%) had smoking experience of more than 20 years.\u0000The research participants were divided into two groups of 30 people each. The groups were comparable by age, duration and severity of symptoms, as well as clinical manifestations of respiratory disease. The patients of the first group took a combined antitussive drug containing codeine, thermopsis extract, licorice root, and sodium bicarbonate for 5 days. Patients of the second group received alternative antitussive drugs.\u0000At the beginning and at the end of treatment, the severity of cough was determined on a visual analog scale and the physical, psychological and social conditions of patients in both groups were assessed using the Leicester Acute Cough Questionnaire.\u0000Results. As a result of the research, it was found that the patients of the first group, who received the combined antitussive drug, have achieved the desired treatment result much earlier and more effectively than the patients of the second group. The intensity of their cough decreased by 2.5 times during the treatment period. The patients of the first group also had better results of treatment, comparing indicators of physical, psychological and social conditions. In the control group, positive results of treatment were determined, although a less significant effect was found.\u0000Conclusions. The conducted study confirmed the high efficiency of the combined antitussive agent, which includes codeine, thermopsis extract, licorice root and sodium bicarbonate, in the treatment of dry debilitating cough caused by ARVI. Thanks to the use of this drug, the severity of cough significantly decreased, which led to a significant improvement in the general condition and quality of life of patients.","PeriodicalId":364588,"journal":{"name":"Family medicine. European practices","volume":"7 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140413459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V. Marichereda, Olexandr Rogachevskyi, Yuliia Prokopchuk, Olha Yehorenko, Olha Komissarova
{"title":"Peculiarities of the Formation of Basic Knowledge on the Emergency Pre-medical Assistance Providing by Persons without Special Medical Education","authors":"V. Marichereda, Olexandr Rogachevskyi, Yuliia Prokopchuk, Olha Yehorenko, Olha Komissarova","doi":"10.30841/2786-720x.1.2024.300455","DOIUrl":"https://doi.org/10.30841/2786-720x.1.2024.300455","url":null,"abstract":"Starting from February 2022, with the beginning of the russian federation’s unprovoked aggression against Ukraine, the time requirements for the direction of the trainings and the contingent for which they are intended have changed significantly. In addition, the issue of rapid spread of knowledge and skills in providing first aid to the injured persons has become very acute. The active help of the international community of higher medical education institutions contributed to the quick and effective training of our teachers as trainers for Basic Life Support (BLS), Stop Bleeding and PHTF courses. The use of innovative digital technologies, modeling of clinical situations, in particular, with the help of distance learning tools, the possibilities of modern simulation technologies and simulators allowed applicants to acquire the necessary theoretical knowledge and master practical skills quickly and at the best level.\u0000The objective: to perform a comparative assessment of the quality of conducting simulation trainings on providing pre-medical care to persons without basic medical education using various teaching techniques.\u0000Materials and methods. The trainings were conducted in two formats - traditional offline study with the participation of an instructor and using the HybridLab method (introduced by the Lithuanian University of Medical Sciences, Kaunas, Republic of Lithuania) for 112 schoolchildren and 27 teachers.\u000058 students and 14 teachers were trained according to the usual method in groups of 5-6 persons, according to the HybridLab method – 54 schoolchildren and 13 teachers in groups of 3-4 individuals. The duration of the trainings was 42 hours. Efficiency was evaluated according to two criteria: the average score of the final test and the indicator of acquiring new knowledge.\u0000Results. A unique combination of methods of organizing the educational process, such as HybridLab, trainings on pre-medical care, which were developed on the basis of the trainings “First on the scene”, “Stop the bleeding” and BLS, and modern tools that allow to evaluate the effectiveness of training, contributed to the achievement a high level of mastery of all the necessary skills by as many people as possible in the shortest time, which is the leading goal of today.\u0000Conclusions. We consider the experience of implementing these knowledge/skills and training methods, as well as the further evaluation of their effectiveness, to be the second task of all medical education institutions and training centers operating in Ukraine, after teaching training on tactical medical training of combatants and emergency tactical medical assistance for medical specialists.","PeriodicalId":364588,"journal":{"name":"Family medicine. European practices","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140415974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Changes in Psychological Profile and Cognitive Function in Patients with Arterial Hypertension Who Have Suffered From COVID-19 Under the Influence of Treatment","authors":"Oleksandr Kuryata, Oleksandr Stadnik","doi":"10.30841/2786-720x.1.2024.300442","DOIUrl":"https://doi.org/10.30841/2786-720x.1.2024.300442","url":null,"abstract":"Today, the issue of treatment and rehabilitation of patients with COVID-19 is extremely relevant. A disease that has shaken the medical community, even after the patient recovers, can have serious consequences for health in the future. The greatest concern in the post-covid period is caused by rather serious and long-term complications (especially in patients who have experienced a severe form of COVID-19), which include: cardiovascular (damage to the heart muscle, exacerbation and progression of hypertension), respiratory, neurological (disturbance of sensation taste and smell, sleep disorders), psychological (depression, anxiety, mood swings) outcomes.\u0000In the modern population, there is an increased level of cognitive disorders. They have multifactorial nature, in particular, one of such pathogenetic factors is arterial hypertension (AH) and its complications, the frequency of post-stroke cognitive impairment from mild to severe grade reaches 60% during the first year. On the other hand, according to observations, treatment of AH can reduce the risk of dementia development. The results of the data analysis showed a higher prevalence of cognitive impairment in patients with AH in the post-epidemic period than in patients with elevated blood pressure (BP) who did not suffer from COVID-19.\u0000The objective: to analyze the frequency of anxiety-depressive disorders and cognitive function in patients with medically controlled AH who experienced COVID-19, and to evaluate the effectiveness of additional use of a combination of L-carnitine, L-arginine and coenzyme Q10 in the post-covid period.\u0000Materials and methods. 53 patients (24 women and 29 men) with a diagnosis of AH who treated with drug antihypertensive therapy and who recovered from COVID-19, were included in a prospective single-center study. Questionnaires (MMSE, SSS-8, PHQ-9) were chosen to assess anxiety-depressive disorders and cognitive function. The study participants were divided into two groups that did not differ in age and gender. In the first group standard treatment was added with a combination of L-arginine, L-carnitine and coenzyme Q10, the patients in the second group received standard therapy.\u0000Results. An additional effect on improved BP control only when used drug therapy in a complex with a combination of L-arginine, L-carnitine and coenzyme Q10 was determined, as well as a positive effect on improved the clinical condition of patients with AH, restoration of the psychological state after a recovery from respiratory infection SARS-COV- 2.\u0000Conclusions. The patients with AH who have suffered from COVID-19 often have psychological changes and impaired cognitive function under the conditions of medical BP control. The use of a combination of L-arginine, L-carnitine and coenzyme Q10 as part of complex therapy contributed to a more effective recovery of psychological and cognitive disorders, improvement of the subjective condition of patients due to the additional positive effect on th","PeriodicalId":364588,"journal":{"name":"Family medicine. European practices","volume":"25 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140408997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Family Doctors Calling in Transcarpathian Region in the Wartime","authors":"P. Kolesnyk, Natalia Kolesnyk, Yurij Sich, Natalia Ponzel, Vladyslav Lazaryk, Oksana Ilkov, Dmytro Hryhorenko, Daniela Petovka","doi":"10.30841/2786-720x.1.2024.300454","DOIUrl":"https://doi.org/10.30841/2786-720x.1.2024.300454","url":null,"abstract":"After the russian invasion, 60,000 refugees from the eastern and southern parts of Ukraine, who had many problems with physical and mental health, arrived in Uzhgorod. A team of family doctors, residents and students with the support of volunteers and various medical, educational, charity and religious organizations started a volunteer project, which later grew into the “InterFamily” clinic.\u0000Starting as a charity center where internally displaced persons could receive free and high quality primary care and medicines purchased through donations from international partners, today it has become a licensed clinic that provides many different medical services (some of which are unique in our region), and as well as primary (i.e. psychological) and secondary care not only to refugees, but also to city residents.\u0000The “InterFamily” clinic is a training center for students and residents who gain hands-on skills and experience, and have the opportunity to become staff members as clinic assistants, providing greater autonomy and the opportunity to gain clinical and management skills.\u0000Thanks to the European-Ukrainian Support In Teaching (later EUSIT-Exchange) project, the European experts have been conducting practical lectures for Ukrainian doctors and nurses and students since the beginning of the war.\u0000The clinic’s innovative medical and educational experience is valuable not only for Ukrainian, but also for foreign specialists. The international recognition of the “InterFamily” clinic was confirmed by the WONCA Europe 5 Star Doctor Award to the director of the “InterFamily” clinic Pavlo Kolesnyk.","PeriodicalId":364588,"journal":{"name":"Family medicine. European practices","volume":"20 36","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140409224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}