Family medicine. European practices最新文献

{"title":"Place of Immunostimulating Drugs in the Treatment of Respiratory Infections","authors":"O. Duda, I.V. Manzheleeva, Valentyna Boyko, Alla Golub, Yu.O. Sukhov","doi":"10.30841/2786-720x.3.2022.273913","DOIUrl":"https://doi.org/10.30841/2786-720x.3.2022.273913","url":null,"abstract":"Every year, influenza and other acute respiratory viral infections (ARVI) cause significant morbidity and mortality worldwide. Most people infected with respiratory viruses have an asymptomatic and uncomplicated course of the disease. ARVI is the most common infectious disease affecting all age groups. Among the causes of temporary loss of working capacity, they occupy the first place – even in the inter-epidemic period, 1/6 of the planet’s population is sick because of them.\u0000The objective: to analyse the efficacy of immunostimulating agent in treatment of ARVI on outpatient level.\u0000Materials and methods. 322 patients from 18 to 65 years old with symptoms of acute respiratory disease participated in the study. Patients were divided into two groups: 250 people who received symptomatic treatment were included in the control group, 72 patients who received symptomatic treatment and immunostimulating drug – in the experimental group.\u0000Results. The study showed that in the experimental group the average time for temperature normalization was 5.0 days, while in the control group it was 7.47 days (p<0.05); disappearance of headache occurs in 5.57 and 7.4 days respectively (p<0.05), disappearance of muscle pain – in 5.0 and 7.4 days (p<0.05).\u0000Conclusions. Non-specific drugs with wide spectrum of action are increasingly used in treatment of acute viral respiratory diseases, in particular, – remedies for stimulation of the immune response in the early stages of the disease, which can significantly shorten the period of fever and improve the general patients wellbeing. Timely treatment with immunostimulants can alleviate the severity and duration of clinical symptoms, help to avoid hospitalization and development of complications, reduce the burden on the outpatient department and use of antibiotics.","PeriodicalId":364588,"journal":{"name":"Family medicine. European practices","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124358727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of Combination Therapy in Patients with Stable Coronary Heart Disease with Comorbid Chronic Obstructive Pulmonary Disease","authors":"O. Kniazieva, V. Potabashnii","doi":"10.30841/2786-720x.3.2022.273919","DOIUrl":"https://doi.org/10.30841/2786-720x.3.2022.273919","url":null,"abstract":"The objective: to analyze the quality of life (QoL) and functional status after combination therapy in patients with stable coronary heart disease (CHD) and comorbid chronic obstructive pulmonary disease (COPD).\u0000Materials and methods. The study included 60 men with stable CHD in combination with COPD. The patients were divided into two groups of 30 people, comparable according to the main indicators. Study group (1) received basic treatment with nebivolol, valsartan, eplerenone, acetylsalicylic acid, rosuvastatin for CHD and basic COPD treatment with combination of umeclidinium bromide (a long-acting cholinolytic) and vilanterol (a long-acting beta2-agonist). Patients from Group 2 in addition tj the basic treatment received L-arginine in the form of an infusion of 4.2% 100 ml solution for 10 days, followed by oral administration at a dose of 3 g per day. The duration of treatment was 6 months.\u0000Quality of life was evaluated by validated standardized non-specific questionnaire «The 36-Item Short Form Health Survey» (SF-36), a validated specific respiratory questionnaire of St. George’s Hospital – St. George’s Respiratory Questionnaire (SGRQ). The functional state of patients before and after treatment was evaluated by cardiorespiratory test, which included the distance 6-minutes walk test (6MWT) according to the standard method in combination with pulse oximetry (SpO2), calculation of desaturation level (ΔSpO2), recording of electrocardiogram and blood pressure before and after exercise.\u0000Results. After the treatment, patients in both groups noted a significant improvement in quality of life across all domains of the SF-36 questionnaire, which includes 36 questions with physical and mental components. Patients from group 2 demonstrated better results of treatment in all indicators of physical functioning, general health and vital activity than patients from group 1. The results of the quality of life evaluation according to the specific respiratory questionnaire SGRQ also showed a significant improvement in patients of both groups. In both groups, the distance of 6MWT significantly increased, the heart rate at rest and after exercise decreased, and the level of desaturation decreased. In group 2, the increase in the distance of 6MWT, the decrease of desaturation level was significantly better than in group 1.\u0000Conclusions. Rational combination treatment of patients with stable coronary heart disease (CHD) with comorbid chronic obstructive pulmonary disease (COPD) includes nebivolol, valsartan, eplerenone, acetylsalicylic acid, rosuvastatin and a combination of vilanterol and umeclidinium bromide, contributes to improving the quality of life of patients and their functional status.\u0000Addition of L-arginine to the basic combination treatment of patients with CHD and COPD increases the efficacy of therapy and improves cardiohemodynamics. Addition of L-arginine to the treatment complex contributed to the additional improvement of the physical and mental pa","PeriodicalId":364588,"journal":{"name":"Family medicine. European practices","volume":"109 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124082362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Formation of Specialist’s Competency Model Is an Important Condition for Quality in Family Doctors Undergraduate Education","authors":"Liliia Babinets, N. Botsyuk, I. Borovyk, Bohdan Migenko","doi":"10.30841/2786-720x.3.2022.273911","DOIUrl":"https://doi.org/10.30841/2786-720x.3.2022.273911","url":null,"abstract":"Competency-oriented training is becoming the main direction of higher education development in Ukraine, which requires implementation of new teaching methods. The main value of project based learning technology lies in directing students to the creation of an intellectual or material product as a result of learning, and not to the simple study of a certain topic. This is a form of organizing classes aimed at developing of communication skills and the ability to work in diverse groups.\u0000The objective: to reveal the essence and methodology of the implementation into the educational process of the project method in teaching the discipline “General practice-family medicine” at undergraduate level at the department of therapy and family medicine of the medical faculty.\u0000Materials and methods. The method of project activity of students was tested as a part of students practice in the “Youth Friendly Clinic”. The basis for the project technology implementation was the presence of the complex medical and social factors that influence teenagers health, which requires integrated knowledge and a research for its solution. Students created and implemented medical and social prevention projects among teenagers.\u0000Results. As a result of working on the project, the students found a specific problem solution and specific result suitable for implementation. This approach creates conditions for creative development and self-realization of students, formation of all necessary professional and general life competencies.\u0000Conclusions. Project technology is the main technology for the formation of key professional and general cultural competences of students, helps students master basic knowledge, acquire communicative and social skills, develops analytical thinking, research skills, and creative abilities.","PeriodicalId":364588,"journal":{"name":"Family medicine. European practices","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122052003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pharmacotherapy of Anxiety Syndrome in Psychosomatic Pathology: Drug Selection Criteria","authors":"S. Burchinsky, N. Bachinskaya, V. Holin","doi":"10.30841/2786-720x.3.2022.273904","DOIUrl":"https://doi.org/10.30841/2786-720x.3.2022.273904","url":null,"abstract":"The article examines modern approaches to the problem of psychoemotional disorders and, in particular, anxiety syndrome in psychosomatic pathology. Special attention is paid to the somatic «masks» of the anxiety syndrome in the most common clinical forms of psychosomatics, as well as the role of chronic stress in the pathogenesis of the specified syndrome and in the occurrence of neurotransmitter imbalance, which is the basis of the development of anxiety disorders.\u0000The advantages and disadvantages of the main groups of drugs used to treat anxiety in patients with various nosological forms of psychosomatic pathology are analyzed. In this regard, special attention is paid to the possibilities of combined phytotherapeutic agents. The advantages of the combination within one dosage form of plant components with proven synergistic anxiolytic action are emphasized. This combination is the original domestic phytotherapeutic agent, which for the first time contains a combination of Vitania extract, L-theanine and Passiflora extract.\u0000The peculiarities of the mechanisms of action of each of the components of the specified combination and the justification of the expediency of their combination from the point of view of the impact on the main pathogenetic mechanisms of the development of the anxiety syndrome are considered. Special attention is paid to the issue of safety during therapy with the specified agent as one of the leading criteria for choosing a tool for the treatment of psycho-emotional disorders in psychosomatic pathology. Reasoned expediency of using the considered phytotherapeutic combination in the treatment of various clinical forms of anxiety disorders in general medical practice.","PeriodicalId":364588,"journal":{"name":"Family medicine. European practices","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125250857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}