Family medicine. European practices最新文献

{"title":"Clinical, Metabolic and Neurohumoral Effects of L-arginine in Patients with Coronary Heart Disease in Combination with Arterial Hypertension","authors":"Hennady Kochuiev, I. Hrek, M. Kochuieva","doi":"10.30841/2786-720x.1.2024.300509","DOIUrl":"https://doi.org/10.30841/2786-720x.1.2024.300509","url":null,"abstract":"The objective: to analyze the impact of complex therapy using L-arginine, ubiquinone (coenzyme Q10), L-carnitine, lycopene, plant extracts and folic acid on the functional state of the endothelium, tolerance to physical activity, indicators of oxidative stress, lipid metabolism and clinical status patients with stable angina pectoris of the III functional class (FC) in comorbidity with arterial hypertension (AH) of the II grade, stage 2.\u0000Materials and methods. 100 patients with stable angina pectoris III FC and AH II grade, stage 2 aged 55–68 years participated in the study. The patients were divided into two groups: 50 patients of the 1st group received standard therapy – RAAS blocker, amlodipine, bisoprolol, acetylsalicylic acid and atorvastatin; 50 patients of the 2nd group in addition to standard therapy received a multi-component product of complex action, which includes L-arginine, ubiquinone (coenzyme Q10), Lcarnitine, lycopene, a number of plant extracts and folic acid, in a dose of 1 sachet per day.\u0000At the beginning and at the end of the study endothelial functions were assessed, daily blood pressure (BP) was monitored, physical exercise testing was performed, the weekly number of angina attacks and nitroglycerin tablet taking were recorded, oxidative status parameters were studied, quality of life was assessed, and the results were statistically processed.\u0000Results. The use of complex action preparation, which includes L-arginine, ubiquinone (coenzyme Q10), L-carnitine, lycopene, plant extracts and folic acid, as adjuvant therapy demonstrated a decrease in the level of indicators of lipid peroxidation (LPO) and an increase levels of antioxidant protection parameters. In the patients of the 2nd group a statistically significant positive dynamics of the blood pressure level was found: the median of daily systolic blood pressure (SBP) decreased to 131.78 mm (p<0.01). A significant decrease in median daytime and nighttime SBP and diastolic blood pressure (DBP) was also determined (p<0.01). The use of a multicomponent preparation of complex action led to a significant decreased of total cholesterol (CHL) by 14.5%, TG by 10.37% and low-density lipoprotein cholesterol by 12.5%. There was also an increased level of high-density lipoprotein cholesterol by 6.48% (р<0.05 for all indicators).\u0000The patients of the 2nd group demonstrated a significant increase in tolerance to physical excesses: an increase in the double product by 21.4% and the total amount of the done work by 78.4% compared to the initial values (р<0.05 for both indicators). After 2 months of treatment the difference between the groups in terms of the decrease in the weekly number of angina attacks was statistically significant (р<0.05). This positive trend was accompanied by a decrease in the median number of nitroglycerin tablets taken per week in the 2nd group from 5.4 to 3.0 (р<0.05). In the patients of the 2nd group after 2 months of observation a statistically significant improv","PeriodicalId":364588,"journal":{"name":"Family medicine. European practices","volume":"12 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140411986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Changes in Psychological Profile and Cognitive Function in Patients with Arterial Hypertension Who Have Suffered From COVID-19 Under the Influence of Treatment","authors":"Oleksandr Kuryata, Oleksandr Stadnik","doi":"10.30841/2786-720x.1.2024.300442","DOIUrl":"https://doi.org/10.30841/2786-720x.1.2024.300442","url":null,"abstract":"Today, the issue of treatment and rehabilitation of patients with COVID-19 is extremely relevant. A disease that has shaken the medical community, even after the patient recovers, can have serious consequences for health in the future. The greatest concern in the post-covid period is caused by rather serious and long-term complications (especially in patients who have experienced a severe form of COVID-19), which include: cardiovascular (damage to the heart muscle, exacerbation and progression of hypertension), respiratory, neurological (disturbance of sensation taste and smell, sleep disorders), psychological (depression, anxiety, mood swings) outcomes.\u0000In the modern population, there is an increased level of cognitive disorders. They have multifactorial nature, in particular, one of such pathogenetic factors is arterial hypertension (AH) and its complications, the frequency of post-stroke cognitive impairment from mild to severe grade reaches 60% during the first year. On the other hand, according to observations, treatment of AH can reduce the risk of dementia development. The results of the data analysis showed a higher prevalence of cognitive impairment in patients with AH in the post-epidemic period than in patients with elevated blood pressure (BP) who did not suffer from COVID-19.\u0000The objective: to analyze the frequency of anxiety-depressive disorders and cognitive function in patients with medically controlled AH who experienced COVID-19, and to evaluate the effectiveness of additional use of a combination of L-carnitine, L-arginine and coenzyme Q10 in the post-covid period.\u0000Materials and methods. 53 patients (24 women and 29 men) with a diagnosis of AH who treated with drug antihypertensive therapy and who recovered from COVID-19, were included in a prospective single-center study. Questionnaires (MMSE, SSS-8, PHQ-9) were chosen to assess anxiety-depressive disorders and cognitive function. The study participants were divided into two groups that did not differ in age and gender. In the first group standard treatment was added with a combination of L-arginine, L-carnitine and coenzyme Q10, the patients in the second group received standard therapy.\u0000Results. An additional effect on improved BP control only when used drug therapy in a complex with a combination of L-arginine, L-carnitine and coenzyme Q10 was determined, as well as a positive effect on improved the clinical condition of patients with AH, restoration of the psychological state after a recovery from respiratory infection SARS-COV- 2.\u0000Conclusions. The patients with AH who have suffered from COVID-19 often have psychological changes and impaired cognitive function under the conditions of medical BP control. The use of a combination of L-arginine, L-carnitine and coenzyme Q10 as part of complex therapy contributed to a more effective recovery of psychological and cognitive disorders, improvement of the subjective condition of patients due to the additional positive effect on th","PeriodicalId":364588,"journal":{"name":"Family medicine. European practices","volume":"25 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140408997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rabies Clinical Perspective: Case Description and Care Strategies","authors":"Dmytro Palii, Halyna Mohnii, Olena Voinalovych","doi":"10.30841/2786-720x.1.2024.300457","DOIUrl":"https://doi.org/10.30841/2786-720x.1.2024.300457","url":null,"abstract":"The information in the article is useful for a wide range of medical professionals, including infectious disease physicians, epidemiologists, traumatologists, family doctors, as well as medical university students.\u0000Rabies is a highly contagious and incurable viral disease that affects the central nervous system that leads to severe encephalitis. This disease is common in 150 countries and territories of the world on all continents except Antarctica. Although the virus can be present in a variety of mammals, the main reservoirs in the wild nature are two specific genera. The most global threat is rabid dogs.\u0000The article analyzes the current situation regarding rabies in Ukraine, with a special emphasis on the Vinnytsia region. By collecting information on the prevalence of rabies cases and analyzing medical records of hospitalized patients, we aim to raise awareness of the severity of the disease and highlight prevention measures.\u0000The clinical case presented in this study is a tool to draw attention to the problem of the spread of rabies. By telling about this case, we hope to inform the society about the frightening consequences of the disease and promote preventive measures.\u0000Solving this issue requires a multifaceted approach. For the effective combat of the rabies spread, it is necessary to review the current restrictions and bans on hunting in the entire territory of Ukraine, in particular in the Vinnytsia region. In addition, more attention should be paid to informing the population through mass media and strengthening the preventive work of medical workers. It is advisable to strengthen control over the vaccination of domestic animals, as this can significantly contribute to the prevention of transmission of the virus. At the same time, it is extremely important to ensure that sufficient quantities of rabies vaccine and immunoglobulin are available for effective treatment and prevention of further cases.","PeriodicalId":364588,"journal":{"name":"Family medicine. European practices","volume":"84 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140411302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimization of the Teaching of Surgical Disciplines in the Training of Family Medicine Specialists at the Undergraduate Level of Education","authors":"Liliia Babinets, Bohdan Migenko","doi":"10.30841/2786-720x.1.2023.277479","DOIUrl":"https://doi.org/10.30841/2786-720x.1.2023.277479","url":null,"abstract":"The quality of medical care for the population depends on the level of training of future doctors. The formation of professional competence of a general practitioner-family doctor requires a wide range of multidisciplinary knowledge. The innovative technologies, especially interactive teaching methods, are used to make the conditions of a successful educational process. A large amount of material that a general practitioner-family doctor should master encourages the introduction of innovative and integral pedagogical methods that optimize the possibilities of acquiring knowledge and the formation of special practical skills, including surgical skills.\u0000The article deals with new views of a comprehensive treatment approach of patients with acute surgical diseases, analyzed modern methods and perspective rehabilitation methodic of surgical patients during the preparing of a general practitioner–family physician at the level of underground education.\u0000On the basis of the analysis of existing educational plans and education programs of doctors in the specialty “General Practice-Family Medicine”, the evaluation of acquired theoretical knowledge, special practical skills and the recommendations on the introduction of innovative and integral methods of teaching the basics were presented.\u0000The article reveals aspects of providing specialized gastroenterological medical care to the population of Ukraine, which today has a significant medical and social importance. Over the last 5 years, the incidence of digestive system and mortality due to diseases has increased.\u0000The study of manifestation, variants of clinical course, diagnostic tactics, diagnosis are extremely relevant at the level of underground education. Knowledge of major diagnostic and tactical errors in acute surgical diseases of the stomach and duodenum is mandatory. Future general practitioners-family doctors need to know the basic clinical signs of acute surgical diseases of the hepatobiliary system and pancreas, improve the skills of taking the patient’s anamnesis (complaints, anamnesis of the disease, history of life, determination of risk factors), need to be able to make an optimal examination plan to confirm the diagnosis, establish a diagnosis, as well as to learn the algorithm of medical history records and be able to determine the period of disability of patients after surgery.\u0000During the stages of the educational process for better study effectiveness interactive, innovative methods, various approaches to diagnosis and treatment. Emergency care and rehabilitation of patients are ought to be used; solving problem situations tasks implement more effective training in surgery for the practical activity of a physician in the specialty “General Practice-Family medicine”.","PeriodicalId":364588,"journal":{"name":"Family medicine. European practices","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128639427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anemic Syndrome and Molecular Mechanisms and Regulation of Iron Absorption in Gastroenterological Diseases","authors":"N. Goryainova, S. Vydyborets, Yurii Derpak, O. Kucher, H. Moroz","doi":"10.30841/2786-720x.1.2023.277472","DOIUrl":"https://doi.org/10.30841/2786-720x.1.2023.277472","url":null,"abstract":"Anemic syndrome is the most often extraintestinal complication in patients with diseases of the digestive tract (DT), which can significantly impair the quality of life. In the literature review, we tried to combine and systematize the accumulated information on the problem of anemic syndrome in DT diseases.\u0000Iron-deficiency anemia, chronic disease anemia, B12-deficiency and folio-deficiency anemia are determined depending on the combination of pathogenetic mechanisms. Other variants of anemia are rare. It is necessary to carry out a complex laboratory examination to establish the leading factor in the development of anemia and determine the adequate therapy. Anemia of inflammatory disease is one of the frequent complications in patients with DT diseases. For the correction of such anemia in clinical practice, iron preparations are used parenterally. However, such therapy can lead to an excess of iron and worsen the course of the underlying disease.\u0000The understanding the anemia pathogenesis is important for prescribing therapy and minimizing the risk of complications. Parenteral forms of iron and vitamin preparations should be prioritized for this category of patients due to their higher bioavailability, low safety profile and minimal negative impact on DT. Erythropoietin preparations and inhibitors of proinflammatory cytokines are mainly used to correct anemia of chronic inflammation. Pro-inflammatory cytokines are effective for patients with anemic syndrome and severe inflammatory bowel processes. According to the literature data, various clinical studies aimed at the introduction of new drugs that correct anemia are being conducted.\u0000The review presents modern methods of diagnosis and treatment of anemia in order to better understand this disease. A further study of patients with gastroenterological diseases, the course of which is complicated by anemia, is necessary to form a final conclusion about the disease, the effectiveness and feasibility of prescribing parenteral forms of iron preparations.","PeriodicalId":364588,"journal":{"name":"Family medicine. European practices","volume":"131 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133310637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anemia in Neoplastic Disease: Current Treatment Options","authors":"Lubov Syvak, Yurii Derpak, Nadiia Goryainova, O. Kucher, H. Moroz","doi":"10.30841/2786-720x.1.2023.277485","DOIUrl":"https://doi.org/10.30841/2786-720x.1.2023.277485","url":null,"abstract":"Anemia is one of the most common complications of cancer. The severity of anemia depends on the severity of the disease and the course of its development. The review of the literature presents the causes and mechanisms of anemia in patients with malignant neoplasms, discussing its negative impact not only on the quality of life, but also on the effectiveness of chemotherapy, existing clinical recommendations for the treatment of anemia with the use of erythropoiesis stimulating agents.\u0000The attention is paid to the effectiveness of modern intravenous iron preparations. A brief overview of the literature data on the problem of use of intravenous iron preparations in clinical practice is presented. The review includes mainly the data of controlled randomized clinical studies, which are considered to be most informative in evidence.\u0000Recently, effective and safe intravenous iron preparations have appeared, the ways of their introduction, doses and formulas have been developed to calculate the overall deficit of iron in the organism. The data on the anemia importance, the incidence of which in tumor diseases, increases constantly, were found.\u0000In numerous randomized studies that have taken place over the open protocol, the value of hemoglobin (Hb) level for the quality of life of cancer patients receiving chemotherapy is demonstrated. Before recombinant human erythropoietins (rHuEPO) the transfusion of erythrocyte mass was used in cancer patients with anemia. However, hemotransfusion could be accompanied by the development of complications, transmission of transmissible infections, post-transfusion reactions, aloimmunization and the effect on the tumor clone with the possibility of stimulating tumor growth.\u0000The safety of iron parenteral preparations has increased because of the creation of a new generation of iron drugs.","PeriodicalId":364588,"journal":{"name":"Family medicine. European practices","volume":"205 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131989831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transplantation Stem Cells: From Definition to Opportunities of Clinical Application","authors":"S. Vydyborets, Yurii Derpak","doi":"10.30841/2786-720x.1.2023.277470","DOIUrl":"https://doi.org/10.30841/2786-720x.1.2023.277470","url":null,"abstract":"The progressive development of embryology, biology, and hematology in the field of experimental research on the biology of SC contribute to the development of new methods and approaches of cellular and tissue therapy for the treatment of pathological conditions and a number of various diseases.\u0000To analyze the information about stem cell (SC) biology, which revealed great possibilities of its use as cellular, gene therapy using both embryonic stem cells (ESC) and SC of an adult organism. The application of ESC requires further study of the clinical possibilities of application in clinical practice, which will directly depend on the limits of tolerance in legal and ethical aspects regarding work with embryonic tissues, the development of an appropriate legislative framework for this field of medicine.\u0000The materials for processing were published information sources, publications of scientific research. Used methods of systematic and structural-logical analysis, bibliosemantic.\u0000It is promising to carry out research on the feasibility of using auto- and allografts of SC hematopoietic tissue obtained from alternative sources, in particular, umbilical cord blood, embryonic liver, bone marrow in clinical transplantation, the development of new transplantation technologies with the use of non-myeloablative modes of conditioning, transplant purification, the use of hematopoietic factors growth of a new generation, vaccination with dendritic cells, etc.\u0000Considering the general aspects of the stem cell (self-renewal, differentiation, plasticity, asymmetric division, niche, stromal support), the possibilities of using embryonic stem cells in regenerative medicine and cell therapy open up. The solution to the problem of SC transplantation gives patients a chance for cure and life extension.","PeriodicalId":364588,"journal":{"name":"Family medicine. European practices","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125055200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of the Quality of Life of Patients with Comorbidity of Hypothireosis and Chronic Pancreatitis","authors":"Olha Salamadze, Liliia Babinets","doi":"10.30841/2786-720x.1.2023.277484","DOIUrl":"https://doi.org/10.30841/2786-720x.1.2023.277484","url":null,"abstract":"Today, comorbidity has been recognized as a global problem of modern medicine around the world. The combined pathology of the thyroid gland and pancreas requires constant search and improvement of an individual approach to the treatment of patients and can improve large-scale socio-economic consequences.\u0000The article presents the analysis of quality of life (QL) of patients with comorbidity of hypothyroidism and chronic pancreatit is (CP).\u0000Materials and methods. The study included 62 inpatient patients with hypothyroidism and concomitant CP, who were treated at the gastroenterology center of the Yuriy Semeniuk Rivne Regional Clinical Hospital. The comparison group involved 48 patients with isolated CP. GSRS (Gastrointestinal Symptom Rating Scale) was used to evaluate the severity of gastroenterological symptoms and QL.\u0000Results. Analyzing the data of the GSRS questionnaire, it was found that in patients with hypothyroidism with concomitant CP, reflux, pain and dyspeptic syndromes were the most common clinical manifestations (p>0.05). According the GSRS questionnaire results, the clinical course of patients with the hypothyroidism was complicated by the comorbidity of the CP, namely: on the scale of gastric reflux – by 48.57 %, on a scale of dyspepsia – by 35.84 %, diarrhea – by 26.94 %, constipation – by 19.93 %, abdominal pain – by 40.81 %.\u0000Conclusions. As a result of the study, the lower level QL in patients with hypothyroidism with concomitant chronic pancreatitis (CP) was established compared to the isolated course of CP. It was determined that the comorbidity of hypothyroidism and CP leads to a complication of the clinical condition of patients.","PeriodicalId":364588,"journal":{"name":"Family medicine. European practices","volume":"47 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134570085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of Motivational Counseling for Lifestyle Modification in Obese Patients Using a Patient-centered Approach","authors":"V. Tkachenko, T. Bagro","doi":"10.30841/2786-720x.1.2023.277475","DOIUrl":"https://doi.org/10.30841/2786-720x.1.2023.277475","url":null,"abstract":"Obesity is a predictor of a significant number of non-communicable diseases. Reduction of body weight by 5–10 % in 6 months, has a positive effect on the prognosis of life and is one of the goals of treatment. To achieve such goals, there is a need for a patient-oriented approach, where the degree of individualization corresponds to the personal risks and needs of the patient with his involvement in the process of choosing a treatment strategy and forming new flexible life habits through the use of motivational counseling.\u0000The objective: is to determine the effectiveness of motivational counseling for lifestyle modification in obese patients of prime working age using a patient-oriented approach.\u0000Materials and methods. 37 patients with obesity I (27 people) and II (10 people) degree, aged 38.03±1.27 years (20 women and 17 men) were examined. Patients were given motivational counseling according to the «5 As» system, the patient-oriented approach included recommendations regarding the regime and caloric content of food, physical activity (monitoring with a pedometer), compliance with sleep hygiene, correction of psycho-emotional disorders.\u0000Clinical laboratory examination in dynamics after 1 month, 3 months and 6 months included measurements of BMI, waist and hip circumference, body surface area, waist/hip ratio, conicity index, body shape index, abdominal volume index, blood pressure, levels of blood glucose, insulin, HOMA index, cholesterol, lipidogram indicators, serotonin and leptin.\u0000In addition, surveys were conducted using the HADS hospital anxiety and depression scale, Beck’s scale, Hamilton scale, Dutch Eating Behavior Questionnaire, Epworth Sleepiness Scale, Pittsburgh Sleep Quality Questionnaire, SF-36, The International Physical Activity Questionnaire, The Finnish Diabetes Risk Score. Statistical analysis was performed using IBM SPSS Statistics, Statistica 12, descriptive statistics Excel 2010.\u0000Results. During 6 months of observation, patients lost more than 5 % of their body weight (p<0.05), which was accompanied by a significant decrease in BMI (p<0.01) and an increase in the level of physical activity (p<0.001). The levels of lipid and carbohydrate metabolism exceeded the recommended values and had a positive tendency to decrease during treatment (p>0.05). Assessments of the manifestations of anxiety and depression according to the HADS depression and Hamilton scales, eating disorders, serotonin and leptin levels, quality of sleep, quality of life of patients improved. The prediction of the risk of developing diabetes had significant positive dynamics (p<0.05).\u0000Conclusions. The obtained results make prove that the application of of motivational counseling according to the step-bystep system «5 As» with a patient-oriented approach in patients of working age with obesity is an effective method, which is confirmed by reliable positive results and allows to reduce body weight by more than 5 % in 6 months, reduce levels of metabolic disord","PeriodicalId":364588,"journal":{"name":"Family medicine. European practices","volume":"62 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125832085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prolongation of Professional Longevity of Patients with Arterial Hypertension in Military Personnel Participating in Modern Armed Conflicts","authors":"A. Voronko, O. Selіuk, A. Buzhenko, M. Selіuk, M. Kozachok, Liliia Dmytruk, Ivan Buzhenko, Oleksii Voronko, Zhanna Buzhenko","doi":"10.30841/2786-720x.1.2023.277478","DOIUrl":"https://doi.org/10.30841/2786-720x.1.2023.277478","url":null,"abstract":"Arterial hypertension (AH) without proper treatment can lead to heart attack, stroke, kidney or heart failure, vision impairment and other complications. The determination of effective preventive measures to prolong siutability for military service based on the health status of experienced military persons with existing comorbid pathology is an urgent issue today and a component of national security.\u0000The objective: to analyze the effective measures that influence on the prolongation of the suitability for military service of military personnel with AH – the participants in the anti terrorist operation / operation of the United Forces (ATO/OUF), taking into account the existing comorbid pathology.\u0000Materials and methods. 213 servicemen – the participants of the ATO/OUF with AH and comorbid pathology were examined, who were divided into two statistically homogeneous groups according to the age. The first group included 126 patients with AH stage I, the second group – 87 persons who were diagnosed with AH stage II. CIRS cumulative disease scale was used to assess comorbidity.\u0000Results. It has been established that the most important prognostic factors (predictors) that influence on the prolongation of the professional longevity of servicemen with AH – the participants of ATO/OUF with comorbid pathology are timely diagnosis and secondary prevention of atherosclerotic cardiovascular diseases, reduction of total cholesterol and triglyceride levels, the prescribtion of hypolipidemic and antiplatelet drugs therapy, normalization of carbohydrate metabolism disorders, body weight and smoking cessation.\u0000Conclusion. The «Algorithm for determination of preventive measures for prolonging suitability for military service based on the health status of servicemen with AH – the participants in ATO/OUF with comorbid pathology was developed».","PeriodicalId":364588,"journal":{"name":"Family medicine. European practices","volume":"83 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114173617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}