中华放射医学与防护杂志最新文献

{"title":"Adverse events of radiotherapy combined with immune checkpoint inhibitors","authors":"F. Sun, L. Xing","doi":"10.3760/CMA.J.ISSN.0254-5098.2019.08.006","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.0254-5098.2019.08.006","url":null,"abstract":"Radiation therapy and immune checkpoint inhibitors(ICI) have a synergistic effect on anti-tumor, which involves a series of complex mechanisms of effects with the immune system, and can improve the clinical outcomes of cancer patients. However, the mechanism by which radiation therapy combined with ICI synergistically modulates the immune response may also trigger treatment-related adverse events. In view of the increasing number of clinical studies and practices of combination therapy, it is necessary to pay attention to the risk of adverse events in combination therapy of radiotherapy and ICI, so as to evaluate the safety of combination therapy. \u0000 \u0000 \u0000Key words: \u0000Radiation therapy; Immune checkpoint inhibitors; Adverse events","PeriodicalId":36403,"journal":{"name":"中华放射医学与防护杂志","volume":"22 1","pages":"594-598"},"PeriodicalIF":0.0,"publicationDate":"2019-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78186446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of volumetric intensity modulated arc therapy (VMAT) combined with chemotherapy in anal squamous cell carcinoma","authors":"Hongzhi Wang, Yang-zi Zhang, J. Geng, Xiang-gao Zhu, Yongheng Li, Y. Cai","doi":"10.3760/CMA.J.ISSN.0254-5098.2019.08.009","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.0254-5098.2019.08.009","url":null,"abstract":"Objective \u0000To investigate the efficacy of concurrent chemoradiotherapy for anal squamous cell carcinoma (ASCC) in the era of intensity-modulated radiotherapy. \u0000 \u0000 \u0000Methods \u0000A total of 19 patients with ASCC who underwent definitive radiotherapy in our hospital since 2011 were collected. The survival curves were depicted with K-M method. Risk factors of disease progression were analyzed using case-control study. \u0000 \u0000 \u0000Results \u0000The median follow-up time was 31 months. The 3 year-LFS and 3 year-OS were 88.1% and 91.7%, respectively. Grade 3 acute toxicities during the chemoradiotherapy were mainly white blood cell reduction (15.8%), platelet reduction (10.5%), diarrhea (15.8%), and skin reaction (31.6%). Compared with historical data, volumetric intensity modulated arc therapy was superior to conventional radiotherapy in the treatment outcome and normal tissue protection in ASCC. Univariate analysis showed that concurrent chemotherapy with capecitabine was a favorable factor in disease progression (P<0.05). \u0000 \u0000 \u0000Conclusions \u0000Volumetric intensity modulated arc therapy for ASCC may have advantages in terms of efficacy and normal tissue protection. Concurrent chemotherapy with a double-drug regimen containing capecitabine may be a beneficial factor in disease progression. \u0000 \u0000 \u0000Key words: \u0000Anal squamous cell carcinoma; Volumetric intensity modulated arc therapy; Concurrent chemotherapy; Efficacy; Toxicity","PeriodicalId":36403,"journal":{"name":"中华放射医学与防护杂志","volume":"15 1","pages":"609-613"},"PeriodicalIF":0.0,"publicationDate":"2019-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84812516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Experimental study of diffusion kurtosis imaging in predicting radiotherapy sensitivity of esophageal carcinoma","authors":"A. Zhang, Yanfei Wang, Xiaohua Su, G. Shi, C. Han, Yang Li, Jun Zhang, Hui Liu","doi":"10.3760/CMA.J.ISSN.0254-5098.2019.08.008","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.0254-5098.2019.08.008","url":null,"abstract":"Objective \u0000To explore the value of diffusion kurtosis imaging (DKI) in predicting radiotherapy sensitivity of esophageal cancer from the animal model level. \u0000 \u0000 \u0000Methods \u0000BALB/c nude mice were subcutaneously injected with Eca-109 cell lines to form xenograft tumors. The tumors received a single dose of 15 Gy (6 MV X-rays) in the experimental group or had no any treatment as control. The volume of transplanted tumor, the change of ADC, MK and MD values, and the tumor cell density and necrosis ratio of these two groups were observed at the corresponding time points. \u0000 \u0000 \u0000Results \u0000The growth of xenograft volume in the experimental group was suppressed and it was significantly smaller than that in the control group (t=3.206-6.149, P<0.05) at the 7th day after radiotherapy. From the 3rd day after radiotherapy, the ADC and MD values of the experimental group were significantly higher than those of the control group, and the MK values was lower than those in the control group (tADC=-11.018--2.049, tMD=-6.609- -2.052, tMK=2.492-9.323, P<0.05). Meanwhile, the tumor cell density of the control group was higher than that of the experimental group, and the proportion of necrosis in the experimental group was higher than that in the control group (tdensity=-8.387--2.239, tnecrosis=2.980-17.430, P<0.05). \u0000 \u0000 \u0000Conclusions \u0000A single large dose radiation could inhibit the growth of xenograft. ADC, MK, MD values changed at the early stage prior to morphological changes of tumor in consistent with the change of cell density and necrosis ratio. DKI has the potential value in predicting radiotherapy sensitivity of esophageal carcinoma. \u0000 \u0000 \u0000Key words: \u0000Diffusion kurtosis imaging(DKI); Diffusion weighted imaging(DWI); Mean diffusion kurtosis(MK); Mean diffusion coefficient(MD); Apparent dispersion coefficient(ADC)","PeriodicalId":36403,"journal":{"name":"中华放射医学与防护杂志","volume":"99 1","pages":"603-608"},"PeriodicalIF":0.0,"publicationDate":"2019-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82780123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The 4Rs in radiation therapy","authors":"W. Luo","doi":"10.3760/CMA.J.ISSN.0254-5098.2019.08.003","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.0254-5098.2019.08.003","url":null,"abstract":"It has been realized that the 4Rs (repair, repopulation, redistribution, and reoxygenation) would affect the result of cell irradiation, and thus radiation treatment. The 4Rs each occurs at different dose rates, usually very low dose rates. Depending on the dose rate used for treatment, the corresponding R should be included in the linear－quadratic equation (LQ) and biological effective dose (BED) calculation. For low dose rate brachytherapy(LDR) especially permanent implant, all the 4Rs should be included in LQ for BED calculation. The 4Rs, especially repair and repopulation, play a critical role in dose fractionation. Various dose fractionation schemes such as hyperfractionation and hypofractionation are determined in consideration of the 4Rs. Stereotactic radiation therapy uses hypofractionation with high fractional doses and combine with high accuracy target localization techniques to achieve high local control rates compared to conventional dose fractionation schemes. The 4Rs have been taken into account for LDR and permanent implant. Recently, LQ for permanent implant brachytherapy has been modified to include all the 4Rs for gynecological malignancy 131Cs permanent implants. Including the 4Rs in radiation therapy has significantly improved the effectiveness and efficiency of radiation therapy for cancer treatment. \u0000 \u0000 \u0000Key words: \u0000Repair; Repopulation; Redistribution; Reoxygenation; Linear quadratic equation","PeriodicalId":36403,"journal":{"name":"中华放射医学与防护杂志","volume":"20 1","pages":"572-580"},"PeriodicalIF":0.0,"publicationDate":"2019-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74442598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The challenges of precision radiotherapy technology to the traditional theory of radiobiology","authors":"Shumei Ma, Zhenzhen Liang, Qiao Chen, Rui Liu, Yutian Guo, Xiaodong Liu","doi":"10.3760/CMA.J.ISSN.0254-5098.2019.08.002","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.0254-5098.2019.08.002","url":null,"abstract":"With the development of modern computing technology and medical physics, radiotherapy has made great progress. The theoretical basis of radiobiology seems to lag behind the clinical application of radiotherapy, which hampers the further improvement of treatment efficacy and the optimization of treatment modality. In this paper, some emerging challenges of precision radiotherapy technology to the traditional theory of radiobiology, such as radiosensitivity, dose-response curve and survival curve, linear-quadratic model, 4Rs theory, as well as the interaction between cancer and microenvironment, radiation-induced second primary cancers (RISPC), will be discussed. The interplay between precision radiotherapy and traditional radiobiology theories will be addressed with the aim to potentially solve some of the challenging problems. \u0000 \u0000 \u0000Key words: \u0000Precision radiotherapy; Radiobiology; Linear－quadratic model; Biological equivalent dose; Radiosensitivity","PeriodicalId":36403,"journal":{"name":"中华放射医学与防护杂志","volume":"7 1","pages":"563-571"},"PeriodicalIF":0.0,"publicationDate":"2019-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87733386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"VEGFR2/STAT3/MMP-9 mediates apatinib-inhibited migration of nasopharyngeal carcinoma cells after radiation","authors":"毛绩伟, Ma Jiwei, 王喆, W. Zhe, 王漂, W. Piao, 梁珊珊, Shanshan Liang, 鞠再双, Ju Zaishuang, 杨亮, Yangfang Liang, 蔡龙玉, Longyu Cai, 王若雨, Wang Ruoyu","doi":"10.3760/CMA.J.ISSN.0254-5098.2019.07.001","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.0254-5098.2019.07.001","url":null,"abstract":"Objective \u0000To investigate the effect of apatinib on the migration ability of nasopharyngeal carcinoma NPC cells after X-ray irradiation and involved protein expressions. \u0000 \u0000 \u0000Methods \u0000The migration abilities of human immortalized nasopharyngeal epithelial cells (NP69) and nasopharyngeal carcinoma cells (CNE-1, CNE-2) treated with different concentrations of apatinib (0, 5, 10 and 15 μmol/L) were compared by wound healing assay. The effect of apatinib on the activity of NPC cells was detected by CCK-8 for determining the suitable intervention concentration of apatinib. Then NPC cells were divided into control group, apatinib group (15 μmol/L), X-ray irradiation group and apatinib combined with X-ray irradiation group, and the migration ability of each group was compared by wound healing assay. The expressions of pVEGFR2, pSTAT3, STAT3, MMP-9 and EMT related proteins were detected by western blot. \u0000 \u0000 \u0000Results \u0000Compared with the NP69, the migration abilities of CNE-1 and CNE-2 were significantly enhanced (t=-5.759, -16.578, P<0.05). Compared with the control group (0 μmol/L), the migration ability of NPC cells after treatment with apatinib(5, 10 and 15 μmol/L)was significantly decreased in a concentration dependent manner (t=2.804-13.362, P<0.05). Compared with the X-ray irradiation group, the wound healing rate of NPC cells in the apatinib combined with X-ray irradiation group was decreased (t=5.932, 2.791, P<0.05), indicating that apatinib can significantly inhibit the migration of NPC cells after X-ray irradiation. Western blot assay showed that the expressions of pVEGFR2 and pSTAT3 were significantly decreased in NPC cells treated with apatinib, meanwhile, the expression of MMP-9 protein was significantly decreased, and the EMT-related protein was changed. \u0000 \u0000 \u0000Conclusions \u0000Apatinib inhibits migration of X-ray irradiated NPC cells by inhibiting EMT through down-regulating VEGFR2/STAT3/MMP-9 signaling pathway. \u0000 \u0000 \u0000Key words: \u0000Nasopharyngeal carcinoma; Apatinib; Migration; MMP-9; EMT","PeriodicalId":36403,"journal":{"name":"中华放射医学与防护杂志","volume":"4 1","pages":"481-486"},"PeriodicalIF":0.0,"publicationDate":"2019-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72903058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"To investigate the effect of scan table on CT size-specific dose estimate in children","authors":"Peng Wei, Tiao Chen, Tian Liao, Zhaoxi Zhang, Lili Zheng, Hao Chen, Yaoyao He, Zilong Yuan","doi":"10.3760/CMA.J.ISSN.0254-5098.2019.07.011","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.0254-5098.2019.07.011","url":null,"abstract":"Objective \u0000To investigate the effect of scan table on size-specific dose estimate (size-specific dose estimate, SSDE) in children′s CT scan. \u0000 \u0000 \u0000Methods \u0000CT imaging data and CTDIvol of 44 children (15 heads, 13 chests, 16 abdomen-pelvis) who underwent Siemens SOMATOM Definition AS+ 64 row 128-slice CT scan were retrospectively collected. CTDIvol of each patient was recored, WED (water equivalent diameter) was calculated by two different methods (with or without table), donated as WED-T and WED-NT, then the corresponding SSDEWED (SSDEWED-T and SSDEWED-NT) was calculated. And the SSDEWED-NT was used as reference to evaluate the difference between WED and SSDEWED obtained by two different methods. \u0000 \u0000 \u0000Results \u0000Including part of table will lead to the overestimate for WED, with mean differences of 0.10%, 2.82% and 2.54% for head, chest and abdomen-pelvis, respectively, while SSDEWED will be underestimated by 0.06% (head), 2.70% (chest) and 1.59% (abdomen-pelvis). \u0000 \u0000 \u0000Conclusions \u0000Including par of the patient table has a certain effect on SSDEWED for children, more attention should be paid for the application of SSDEWED. \u0000 \u0000 \u0000Key words: \u0000Water equivalent diameter; Size-specific dose estimate; Children; Radiation dose; Computed tomography","PeriodicalId":36403,"journal":{"name":"中华放射医学与防护杂志","volume":"11 1","pages":"539-543"},"PeriodicalIF":0.0,"publicationDate":"2019-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77856779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of the efficacy of neoadjuvant radiotherapy and adjuvant radiotherapy for patients with T3N0 stage esophageal cancer","authors":"田文泽, Tian Wenze, 尤振兵, Zhenbing You, 胡忠吾, Zhongwu Hu, 徐达夫, Xu Dafu, 徐克平, Keping Xu","doi":"10.3760/CMA.J.ISSN.0254-5098.2019.07.005","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.0254-5098.2019.07.005","url":null,"abstract":"Objective \u0000To compare the efficacy of neoadjuvant radiotherapy and adjuvant radiotherapy in the treatment of patients who underwent radical esophagectomy for T3N0 stage. \u0000 \u0000 \u0000Methods \u0000Totally 555 cases of T3N0, who underwent t neoadjuvant radiotherapy or adjuvant radiotherapy from 2004 to 2014, were selected from the SEER cancer registry in this study. 486 cases received neoadjuvant radiotherapy (neoadjuvant radiotherapy group) and 69 cases received adjuvant radiotherapy (adjuvant radiotherapy group). Kaplan-Meier (KM) survival and multivariate Cox regression analyses were used to analyze the overall survival (OS) and cancer specify survival (CSS) of the two groups. A propensity score model was utilized to balance the baseline covariates. \u0000 \u0000 \u0000Results \u0000The CSS in the neoadjuvant radiotherapy group was significantly better than that in the adjuvant radiotherapy group (χ2=6.030, P<0.05). Multivariate COX regression analysis showed that age, gender, and radiotherapy sequence with surgery were important factors influencing the prognosis of esophageal cancer with T3N0 stage (Wald=10.099, 10.562, 4.331, P<0.05). Compared with the neoadjuvant radiotherapy group, the adjuvant radiotherapy group had a worse CSS (hazard ratio: 1.649, 95%CI 1.173-2.316, P=0.004) and OS (hazard ratio: 1.402, 95%CI 1.020-1.928, P=0.037). According to K-M survival analysis, the adjuvant radiotherapy group showed the worse CSS (hazard ratio: 1.813, 95%CI 1.072-3.069, P=0.027) and OS (hazard ratio: 1.424, 95% CI 0.896-2.262, P=0.134) than the neoadjuvant radiotherapy in esophageal cancer with T3N0 stage, which was similar to the matched cohort. \u0000 \u0000 \u0000Conclusions \u0000Compared with postoperative adjuvant radiotherapy, neoadjuvant radiotherapy significantly improves the CSS and OS of T3N0 patients with esophageal cancer. \u0000 \u0000 \u0000Key words: \u0000Esophageal cancer; Neoadjuvant radiotherapy; Adjuvant radiotherapy","PeriodicalId":36403,"journal":{"name":"中华放射医学与防护杂志","volume":"125 1","pages":"506-510"},"PeriodicalIF":0.0,"publicationDate":"2019-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78468438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Monitoring and analysis of total α and total β levels in drinking water around Qinshan Nuclear Power Plsnt in 2018","authors":"Zhenggui Ding, S. Lyu, Z. Hu","doi":"10.3760/CMA.J.ISSN.0254-5098.2019.07.007","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.0254-5098.2019.07.007","url":null,"abstract":"Objective \u0000To ascertain the background levels of total α and total β radioactivity in drinking water around Qianshan Nuclear Power Plant (QNPP). \u0000 \u0000 \u0000Methods \u0000Under the National Health and Wellness Committee′s program, 11 monitoring points within 30 km of QNPP were selected in Haiyan County in 2018. The samples of raw water, factory water and tap water were collected in the first half and the second half of the year, respectively, and determined and analyzed according to Standard Examination Methods for Drinking Water - Radiological Parameters (GB/T 5750.13-2006). The total α and total β levels in the tested drinking water were evaluated under the Standards for Drinking Water Quality (GB 5749-2006) . \u0000 \u0000 \u0000Results \u0000A total of 22 water samples were collected from 11 sampling points in April and September 2018, respectively. The residue rate obtained after drinking water was dried varied, dependent on different types of water, which could be up to 0.033 7%. The total α levels in different types of water ranged from 0.008 to 0.04 Bq/L, averaged on (0.015±0.009) Bq/L, whereas the total β levels ranged from 0.014 to 0.320 Bq/L with an average of (0.188±0.068) Bq/L. There was statistically significant difference in total α levels between raw water and factory water (Z=-2.286, P 0.05). The background levels of total α and total β radioactivity in 93 drinking water samples in 2016 and 2017 were also investigated, combined with a total of 115 water samples from different water bodies in 2018. There was statistically significant difference in total α and total β levels in tap water between 2017—2016 and 2018 (Z= -2.976, -2.031, P<0.05), between 2016 and 2017 (Z=-2.042, -3.214, P<0.05) and between 2017 and 2018 (Z=-20.112, -2.511, P<0.05). \u0000 \u0000 \u0000Conclusions \u0000The operation of nuclear power plant has no impact on radioactivity level in drinking water around QNPP. The drinking water around QNPP is safe. \u0000 \u0000 \u0000Key words: \u0000Drinking water; Radioactive level; Residue rate","PeriodicalId":36403,"journal":{"name":"中华放射医学与防护杂志","volume":"7 1","pages":"517-522"},"PeriodicalIF":0.0,"publicationDate":"2019-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88737028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Progress of surgery combined with radiotherapy for primary hepatocellular carcinoma","authors":"Yanling Wu","doi":"10.3760/CMA.J.ISSN.0254-5098.2019.07.014","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.0254-5098.2019.07.014","url":null,"abstract":"Hepatocellular carcinoma (HCC) is a common malignant tumor that seriously endangers human health. Surgical resection is the main radical treatment for early and mid-stage HCC, but the recurrence rate is high. At present, there is no effectively and universally accepted adjuvant therapy to reduce the high postoperative recurrence rate. With the development of precise radiotherapy technology, the safe and higher radiation doses can be used in tumors locally. Therefore, radiotherapy is increasingly applied to the treatment of HCC. At present, the position of radiotherapy in the treatment of advanced HCC has become more and more clear. However, the position in the adjuvant treatment of HCC has not been clear. This article will review the research of radiotherapy as adjuvant therapy for surgery in HCC, so as to provide reference for the application of clinical adjuvant therapy for HCC. \u0000 \u0000 \u0000Key words: \u0000Hepatocellular carcinoma; Surgery; Radiotherapy","PeriodicalId":36403,"journal":{"name":"中华放射医学与防护杂志","volume":"29 1","pages":"554-557"},"PeriodicalIF":0.0,"publicationDate":"2019-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75451231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}