Journal of Hazardous Materials最新文献_第3页

Accumulation of Lipophilic and Proteinophilic Halogenated Organic Pollutants (HOPs) in the Different Types of Feathers of Laying Hens

IF 13.6 1区环境科学与生态学

Journal of Hazardous Materials Pub Date : 2024-12-19 DOI: 10.1016/j.jhazmat.2024.136942

Xi Chen, Xiao-Jun Luo, Qun-Jie Feng, Yu Liu, Jun-Zhe Dai, Peng-Peng Chen, Pei-Xin Su, Qing-Rong Yang, Yan-Hong Zeng, Bi-Xian Mai

{"title":"Accumulation of Lipophilic and Proteinophilic Halogenated Organic Pollutants (HOPs) in the Different Types of Feathers of Laying Hens","authors":"Xi Chen, Xiao-Jun Luo, Qun-Jie Feng, Yu Liu, Jun-Zhe Dai, Peng-Peng Chen, Pei-Xin Su, Qing-Rong Yang, Yan-Hong Zeng, Bi-Xian Mai","doi":"10.1016/j.jhazmat.2024.136942","DOIUrl":"https://doi.org/10.1016/j.jhazmat.2024.136942","url":null,"abstract":"This study investigated the bioaccumulation of halogenated organic pollutants (HOPs) in three types of feathers from laying hens through exposure experiments. The HOPs included lipophilic polychlorinated biphenyls (PCBs) and polybrominated diphenyl ethers (PBDEs), as well as proteinophilic perfluoroalkyl carboxylic acids (PFCAs). Concentrations of PCBs, PBDEs, and short-chain PFCAs (≤8) were significantly higher in the body feathers than in the primary feathers, while long-chain PFCAs (>8) showed no significant differences among primary, tail, and body feathers. The concentration order in the feathers was ∑12PFCAs > ∑7PBDEs > ∑13PCBs, which was completely reversed by the exposure dose. The transfer rates (TRs) (concentration ratio of feather to serum) of PFCAs (0.11–6.8) were one order of magnitude higher than those (0.01–0.30) of PCBs and PBDEs. These results indicate that PFCAs preferentially accumulate in feathers compared to PBDEs and PCBs. TRs, regardless of whether they were lipophilic or proteinophilic HOPs, were significantly and positively correlated with the protein-water partition coefficient (log Kpw). Strong and significant correlations between feathers and inner tissues were primarily observed in body feathers. Egg-laying significantly affects PFCA accumulation in feathers and even distorts the actual exposure dose in hens; however, its impact on PCBs and PBDEs is limited. These findings provide crucial insights into HOP deposition in bird feathers.","PeriodicalId":361,"journal":{"name":"Journal of Hazardous Materials","volume":"82 1","pages":""},"PeriodicalIF":13.6,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142857931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Amplified growth and heavy metal toxicity of Chlorococcum sp. from exposure to low-dose Lanthanum(III) 暴露于低剂量镧(III)的氯球藻的增殖和重金属毒性

IF 13.6 1区环境科学与生态学

Journal of Hazardous Materials Pub Date : 2024-12-19 DOI: 10.1016/j.jhazmat.2024.136949

Yongqiang Liu, Yue Ben, Lihong Wang, Xiaohua Huang, Qing Zhou

{"title":"Amplified growth and heavy metal toxicity of Chlorococcum sp. from exposure to low-dose Lanthanum(III)","authors":"Yongqiang Liu, Yue Ben, Lihong Wang, Xiaohua Huang, Qing Zhou","doi":"10.1016/j.jhazmat.2024.136949","DOIUrl":"https://doi.org/10.1016/j.jhazmat.2024.136949","url":null,"abstract":"Rare earth elements (REEs) are extensively utilized in industry, agriculture, advanced materials and other fields, leading to their dispersion in water bodies as emerging contaminants. Meanwhile, the coexistence of REEs and heavy metals (HMs) has become a novel form of water contamination (REE-HM co-contamination), though scientists have limited understanding of its hazards. Here, Chlorococcum sp. cultured in Taihu Lake water was selected to examine the effects of low-dose lanthanum(III) [La(III)] on its growth and HM accumulation. Low-dose La(III) (0.5-30 μg/L) promoted algal growth and increased the contents of Cd (136.7%), Pb (92.0%), and Cr (84.3%), along with the bioconcentration factor of Cd (135.5%), Pb(91.7%), and Cr(84.0%) in Chlorococcum sp. These changes were attributed to La(III)-induced adaptive physiological regulations, including essential element uptake, photosynthesis, and antioxidant enzyme activities, achieved through La(III)-enhanced clathrin-mediated endocytosis. In summary, low-dose La(III) increased the growth and HM accumulation of Chlorococcum sp. in REE-HM co-contaminated water. This phenomenon amplified the toxicity of Chlorococcum sp., causing the HM accumulation in predators in the grazing food chain and posing a new threat to aquatic ecosystems.","PeriodicalId":361,"journal":{"name":"Journal of Hazardous Materials","volume":"37 1","pages":""},"PeriodicalIF":13.6,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142849355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Early-warning ecological risk assessments of multi-element pollution in the surface soil of karst basins in southwest China based on the delayed geochemical hazard model

IF 13.6 1区环境科学与生态学

Journal of Hazardous Materials Pub Date : 2024-12-18 DOI: 10.1016/j.jhazmat.2024.136935

Jie Luo, Jie Li, Siyao Feng, Xinying Ke

{"title":"Early-warning ecological risk assessments of multi-element pollution in the surface soil of karst basins in southwest China based on the delayed geochemical hazard model","authors":"Jie Luo, Jie Li, Siyao Feng, Xinying Ke","doi":"10.1016/j.jhazmat.2024.136935","DOIUrl":"https://doi.org/10.1016/j.jhazmat.2024.136935","url":null,"abstract":"Soil potentially toxic element (PTE) pollution, especially in karst regions, poses significant ecological risks due to the unique geological features and environmental conditions. This study focuses on the delayed geochemical hazard (DGH) model to assess the progressive risks of cadmium (Cd) and lead (Pb) contamination in the surface soils of karst regions in southwestern China. The study found that Pb and Cd pollution in karst areas presents ecological risks, with the region's high porosity and alkaline soils facilitating the transformation of pollutants from stable to mobile forms. The analysis revealed that Pb underwent multidirectional transformations, with 28.3% of the soil showing a transition from carbonate-bound Pb (PbC) to exchangeable Pb (PbE). However, Cd primarily transformed into carbonate-bound (CdC) and oxide-bound (CdO) forms, with 3.77% of samples exhibiting the highest outbreak probability for the pathway from sum Cd (CdE+C+F+O+R) to CdC+O. In Pb-Cd co-contamination, Cd predominates, altering risk pathways by triggering transformations at iron-manganese oxide and organic matter binding sites, thereby increasing pollutant mobility. The most prominent combined risk pathway in Pb-Cd contamination was the shift from ME+O to MC (outbreak probability: 5.66%), indicating enhanced mobility of both PTEs. New pathways also emerged, such as the transition from ME+C+F+O to ME+C, suggesting that Pb and Cd interactions accelerate the risk evolution, favoring highly mobile forms. These findings highlight the importance of not only considering total PTE concentrations but also their speciation and potential transformations in risk assessments. The DGH model effectively predicts evolutionary risks in co-contaminated karst areas, providing insights for early warning of multi-element pollution, particularly in vulnerable karst landscapes.","PeriodicalId":361,"journal":{"name":"Journal of Hazardous Materials","volume":"27 1","pages":""},"PeriodicalIF":13.6,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142841407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Engineering oxygen vacancies in acid-etched MgMn2O4 for efficiently catalytic benzene combustion: Synergistic activation of gaseous oxygen and surface lattice oxygen

IF 13.6 1区环境科学与生态学

Journal of Hazardous Materials Pub Date : 2024-12-18 DOI: 10.1016/j.jhazmat.2024.136907

Yu Wu, Dongjing Lei, Aijie Wang, Qiuyan Zhang, Hongwei Jian, Haojie Yang, Chong Han

{"title":"Engineering oxygen vacancies in acid-etched MgMn2O4 for efficiently catalytic benzene combustion: Synergistic activation of gaseous oxygen and surface lattice oxygen","authors":"Yu Wu, Dongjing Lei, Aijie Wang, Qiuyan Zhang, Hongwei Jian, Haojie Yang, Chong Han","doi":"10.1016/j.jhazmat.2024.136907","DOIUrl":"https://doi.org/10.1016/j.jhazmat.2024.136907","url":null,"abstract":"The synergistic activation of gaseous oxygen and surface lattice oxygen is essential for designing highly efficient catalysts to eliminate VOCs. Herein, an effective acid treatment was carried out to create more oxygen vacancies by modulating the electronic structure of MgMn2O4 spinels and MgMnOx mixed oxides. The acid-treated MgMn2O4 exhibited outstanding catalytic performance, with the reaction rate of benzene rising by 8.55 times at 200 °C. After acid treatment, MgMn2O4 partially retained its spinel structure, while Mn2O3 in situ grew on the surface due to the selective removal of Mg2+. The transformation of Mn–O–Mg into Mn–O weakened the strength of adjacent Mn–O bonds, thereby promoting the release of surface lattice oxygen and the regeneration of oxygen vacancies. In addition, acid-treated MgMn2O4 facilitated the adsorption and activation of gaseous oxygen. In situ DRIFTS analysis proved that the synergistic activation of gaseous oxygen and surface lattice oxygen accelerated the conversion of intermediates, thus contributing to the efficient degradation of benzene.","PeriodicalId":361,"journal":{"name":"Journal of Hazardous Materials","volume":"25 1","pages":""},"PeriodicalIF":13.6,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142841409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Harmless treatment of cyanide tailings by functional bacteria: Degradation of cyanide and the secondary pollutant ammonia nitrogen

IF 13.6 1区环境科学与生态学

Journal of Hazardous Materials Pub Date : 2024-12-18 DOI: 10.1016/j.jhazmat.2024.136939

Chongzhe Chi, Ye Zheng, Yujia Shi, Cong Lyu, Xiangzheng Jiang, Yu Zhang, Chunhui Wang

{"title":"Harmless treatment of cyanide tailings by functional bacteria: Degradation of cyanide and the secondary pollutant ammonia nitrogen","authors":"Chongzhe Chi, Ye Zheng, Yujia Shi, Cong Lyu, Xiangzheng Jiang, Yu Zhang, Chunhui Wang","doi":"10.1016/j.jhazmat.2024.136939","DOIUrl":"https://doi.org/10.1016/j.jhazmat.2024.136939","url":null,"abstract":"The eco-friendly treatment of cyanide tailings (CT) using microorganisms is a cost-effective and promising technology. However, this process often generates the secondary pollutants, such as ammonia nitrogen (NH4+–N), which can adversely impacts the surrounding environment. The accumulation of NH4+–N is also toxic to cyanide-degrading microorganisms, presenting a significant challenge in achieving simultaneous cyanide degradation and NH₄⁺–N mitigation. In this study, a group of functional bacteria CG305-1 with the ability to degrade cyanide and perform nitrification and denitrification was successfully enriched for the first time and used to treat CT by in situ microbial drenching technology. Results demonstrated that the total cyanide (CNT) concentration in the leaching solution decreased from 49.96 ± 1.51 mg/L to 0.19 ± 1.11 mg/L. NH₄⁺–N was degraded to 0.25 ± 0.18 mg/L, and nitrate nitrogen (NO3––N) was reduced to 0.41 ± 0.20 mg/L. Furthermore, CNT in the CT leachate was reduced to 0.94 ± 0.11 mg/L, meeting the storage standard for CT leachate (CNT < 5 mg/L). The potential synergistic microbial degradation mechanisms were elucidated through scanning electron microscopy (SEM), Fourier-transform infrared spectroscopy (FTIR), and metagenomic sequencing. This study provides significant insights into green and sustainable methods for the harmless treatment of CT.","PeriodicalId":361,"journal":{"name":"Journal of Hazardous Materials","volume":"30 1","pages":""},"PeriodicalIF":13.6,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142841410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Perfluorobutanoic acid: a short-chain perfluoroalkyl substance exhibiting estrogenic effects through the estrogen-related receptor γ pathways

IF 13.6 1区环境科学与生态学

Journal of Hazardous Materials Pub Date : 2024-12-18 DOI: 10.1016/j.jhazmat.2024.136947

Fangfang Li, Lu Chen, Sha Shi, Wen-Jun Hong, Minjie Li, Liang-Hong Guo

{"title":"Perfluorobutanoic acid: a short-chain perfluoroalkyl substance exhibiting estrogenic effects through the estrogen-related receptor γ pathways","authors":"Fangfang Li, Lu Chen, Sha Shi, Wen-Jun Hong, Minjie Li, Liang-Hong Guo","doi":"10.1016/j.jhazmat.2024.136947","DOIUrl":"https://doi.org/10.1016/j.jhazmat.2024.136947","url":null,"abstract":"Perfluorobutanoic acid (PFBA) is an emerging contaminant that was demonstrated to exhibit estrogen effects via action on classic estrogen receptors (ERs) in a low-activity manner. The purpose of the present study is to reveal the estrogen disruption effect and mechanism of PFBA via estrogen-related receptors γ (ERRγ) pathways. In vivo experiment indicated that PFBA accumulated in zebrafish ovary and caused ovarian injury, with disturbing sex hormone levels and interfering gene expression related to estrogen synthesis and follicle regulation. In vitro, with cell proliferation assay, PFBA could promote estrogen-sensitive endometrial cancer cell Ishikawa proliferation at lowest observed effective concentrations (LOEC) 10 nM, which was close to human exposure levels. And cell proliferation was inhibited by ERRγ antagonist GSK5182. By fluorescence competitive binding assay, molecular docking and luciferase reporter gene assays, it demonstrated that PFBA could directly bind with ERRγ and activate ERRγ transcriptional activities with a LOEC of 10 nM. Furthermore, PFBA up-regulated the proliferation-related factors downstream of ERRγ and inhibited by PI3K/Akt inhibitor LY294002, which also suppressed the cell proliferation induced by PFBA. Taken together, the results revealed that PFBA had estrogen effects at the human-related exposure concentration, and demonstrated a new estrogen effects mechanism of PFBA via ERRγ pathway.","PeriodicalId":361,"journal":{"name":"Journal of Hazardous Materials","volume":"14 1","pages":""},"PeriodicalIF":13.6,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142849390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Simple and rapid capillarity-assisted ultra-trace detection of thiram on apple surface with a silver nanoparticles/filter paper SERS substrate 利用银纳米颗粒/滤纸 SERS 基底，简单快速地毛细管辅助超痕量检测苹果表面的福双美

IF 13.6 1区环境科学与生态学

Journal of Hazardous Materials Pub Date : 2024-12-18 DOI: 10.1016/j.jhazmat.2024.136945

Jun Cheng, Shunqian Zhuang, Zhewen Luo, Songting Chen, Yao Shen, Jian Ye, Zhilong Yu, Tiancong Zhao, Yunfei Xie

{"title":"Simple and rapid capillarity-assisted ultra-trace detection of thiram on apple surface with a silver nanoparticles/filter paper SERS substrate","authors":"Jun Cheng, Shunqian Zhuang, Zhewen Luo, Songting Chen, Yao Shen, Jian Ye, Zhilong Yu, Tiancong Zhao, Yunfei Xie","doi":"10.1016/j.jhazmat.2024.136945","DOIUrl":"https://doi.org/10.1016/j.jhazmat.2024.136945","url":null,"abstract":"Thiram is a readily synthesized, cost-effective antimicrobial agent widely used to control diseases in fruits and vegetables. Given the potential health hazards associated with thiram residues and advancements in detection methods, it is crucial to develop a rapid and sensitive technique for detecting these residues on fruit surfaces. Here, we prepared the Ag@filter paper (Ag@FP) surface-enhanced Raman scattering (SERS) substrate in a controlled manner and innovatively developed a capillarity-assisted SERS (CA-SERS) detection method. Sampling can be completed in less than 1 min by either wiping or using the CA-SERS method. Utilizing a portable Raman device, the detection limit for thiram residues on apple surfaces can reach as low as 0.005 ng/cm2 with the CA-SERS detection method. Furthermore, the substrate is cost-effective, can be prepared in just 7 min, and remains stable at room temperature for up to 40 days. Additionally, we developed a cost-effective, centimeter-scale auxiliary detection device to facilitate efficient on-site detection.","PeriodicalId":361,"journal":{"name":"Journal of Hazardous Materials","volume":"30 1","pages":""},"PeriodicalIF":13.6,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142849356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dissecting the mechanisms of copper-azole wood preservatives detoxification by ligninolytic fungi

IF 13.6 1区环境科学与生态学

Journal of Hazardous Materials Pub Date : 2024-12-18 DOI: 10.1016/j.jhazmat.2024.136934

Carla Vandekerkhove, Raphael Bchini, Tiphaine Dhalleine, Annegret Kohler, Aurélie Deveau, Gaurav Pandharikar, Arnaud Besserer, Rodnay Sormani, Sylvain Darnet, Mélanie Morel-Rouhier

{"title":"Dissecting the mechanisms of copper-azole wood preservatives detoxification by ligninolytic fungi","authors":"Carla Vandekerkhove, Raphael Bchini, Tiphaine Dhalleine, Annegret Kohler, Aurélie Deveau, Gaurav Pandharikar, Arnaud Besserer, Rodnay Sormani, Sylvain Darnet, Mélanie Morel-Rouhier","doi":"10.1016/j.jhazmat.2024.136934","DOIUrl":"https://doi.org/10.1016/j.jhazmat.2024.136934","url":null,"abstract":"Copper-azole based formulations have been widely used to protect wood timbers against fungal decay. While these treatments are efficient for wood protection, leaching of both copper and azoles into the environment has deleterious impact on soils and surface waters. No bioremediation process is currently available for disposable of these wood wastes. Exploiting the natural ability of certain fungi to tolerate these active compounds, we propose that some ligninolytic fungi could serve as effective biocatalysts for detoxifying copper-azole formulations. Using the white-rot fungus Phanerochaete chrysosporium as a model, we demonstrated that these fungi engage multiple strategies to counteract the antifungal effect of azoles present in the preservatives. These include the modulation of the lipids and sterols content, the maintenance of DNA integrity, detoxification of azoles by extracellular degradation likely through the Fenton chemistry, biosorption at the cell wall, efflux, and intracellular detoxification by the three-step detoxification pathway. By using comparative transcriptomics between a copper-azole formulation and a copper-quaternary ammonium formulation, we identified genes specifically involved in azole resistance and detoxification within this complex system. This opens new perspectives for managing azoles residues through mycoremediation processes.","PeriodicalId":361,"journal":{"name":"Journal of Hazardous Materials","volume":"52 1","pages":""},"PeriodicalIF":13.6,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142841411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bioaccumulation and potential human health risks of PAHs in marine food webs: A trophic transfer perspective 多环芳烃在海洋食物网中的生物累积和对人类健康的潜在风险：营养转移视角

IF 13.6 1区环境科学与生态学

Journal of Hazardous Materials Pub Date : 2024-12-18 DOI: 10.1016/j.jhazmat.2024.136946

Huijuan Wang, Yilan Shu, Zexing Kuang, Zilin Han, Jiaheng Wu, Xinmiao Huang, Xiaoyong Song, Jing Yang, Zhengqiu Fan

{"title":"Bioaccumulation and potential human health risks of PAHs in marine food webs: A trophic transfer perspective","authors":"Huijuan Wang, Yilan Shu, Zexing Kuang, Zilin Han, Jiaheng Wu, Xinmiao Huang, Xiaoyong Song, Jing Yang, Zhengqiu Fan","doi":"10.1016/j.jhazmat.2024.136946","DOIUrl":"https://doi.org/10.1016/j.jhazmat.2024.136946","url":null,"abstract":"Polycyclic aromatic hydrocarbons (PAHs) are persistent pollutants in aquatic environments that can accumulate in marine organisms and pose potential health risks to humans through trophic transfer in the food webs. However, the accumulation and health risks of PAHs in organisms at different trophic levels remain unclear. This study investigated the accumulation and trophic transfer of PAHs in 40 marine organisms from Beibu Gulf (China), and assessed their health risks. Utilizing the trophic level spectrum constructed with stable isotope methods, the organisms were categorized into three trophic levels: Omnivorous (15.00%), low-level carnivorous (67.50%), and mid-level carnivorous (17.50%). The contamination levels of total PAHs in these organisms ranged from \"mild pollution\" to \"moderate pollution\", with all organisms exhibiting significant PAH accumulation (Bioconcentration factor value > 2000). Total PAH concentrations increased with higher trophic levels, following the trend of mid-level carnivores > low-level carnivores > omnivores. Notably, only three PAH compounds (Nap, Fla and Phe) showed biomagnification effects, while the others exhibited trophic dilution. Carcinogenic risk assessment indicated an “Unacceptable risk” level for all populations, with the highest risk due to consumption of mid-level carnivorous. These findings offer new insights into the accumulation and health risks of PAHs from a trophic transfer perspective.","PeriodicalId":361,"journal":{"name":"Journal of Hazardous Materials","volume":"1 1","pages":""},"PeriodicalIF":13.6,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142849391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development of a novel NIR-II fluorescence probe for monitoring serum albumin fluctuation in cerebra neurotoxicity induced by Manganese exposure

IF 13.6 1区环境科学与生态学

Journal of Hazardous Materials Pub Date : 2024-12-18 DOI: 10.1016/j.jhazmat.2024.136936

Xing Liang, Luolin Wang, Lizhen Xu, Hanwen Chi, Weiying Lin

{"title":"Development of a novel NIR-II fluorescence probe for monitoring serum albumin fluctuation in cerebra neurotoxicity induced by Manganese exposure","authors":"Xing Liang, Luolin Wang, Lizhen Xu, Hanwen Chi, Weiying Lin","doi":"10.1016/j.jhazmat.2024.136936","DOIUrl":"https://doi.org/10.1016/j.jhazmat.2024.136936","url":null,"abstract":"Manganese is essential for various biological functions; however, excessive exposure can lead to significant health risks, particularly brain neurotoxicity. Understanding manganese-induced alterations in brain serum protein levels and brain function is crucial for elucidating the mechanisms underlying manganese neurotoxicity. To address this, we developed a novel NIR-II fluorescent probe, RSM, characterized by robust binding to serum albumin and high sensitivity. Using RSM, we observed that heightened BSA uptake in cells exposed to elevated manganese concentrations relative to those exposed to lower levels. Furthermore, we successfully detected changes in serum albumin levels induced by manganese neurotoxicity in brain tissue through in situ NIR-II fluorescence imaging. Our findings establish an association between augmented manganese-induced neurotoxicity and elevated serum albumin content in the brain. This work provides a valuable tool for further investigating the mechanisms of toxic molecules.","PeriodicalId":361,"journal":{"name":"Journal of Hazardous Materials","volume":"17 1","pages":""},"PeriodicalIF":13.6,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142841412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0