The Innovation最新文献_第4页

GSAman: A gene-structure annotation manual curator for functional genomics research. GSAman：功能基因组学研究的基因结构注释手册管理员。

IF 39.5 1区综合性期刊

The Innovation Pub Date : 2026-06-17 eCollection Date: 2026-10-05 DOI: 10.1016/j.xinn.2026.101471

Chengjie Chen, Ya Wu, Kangning Feng, Hongsen Liu, Yi Liao, Zaohai Zeng, Fengqi Wu, Mengjin Tan, Xiaolong Xu, Songlin Huang, Zihao Wang, Shuyuan Tang, Weijian Sun, Jisen Zhang, Ling-Ling Chen, Rui Xia

{"title":"GSAman: A gene-structure annotation manual curator for functional genomics research.","authors":"Chengjie Chen, Ya Wu, Kangning Feng, Hongsen Liu, Yi Liao, Zaohai Zeng, Fengqi Wu, Mengjin Tan, Xiaolong Xu, Songlin Huang, Zihao Wang, Shuyuan Tang, Weijian Sun, Jisen Zhang, Ling-Ling Chen, Rui Xia","doi":"10.1016/j.xinn.2026.101471","DOIUrl":"10.1016/j.xinn.2026.101471","url":null,"abstract":"A high-quality reference genome requires not only accurate DNA sequences but also well-defined gene-structure annotations. However, many existing tools depend predominantly on automated pipelines that perform poorly when confronted with complex gene architectures, such as overlapping loci, alternative splicing patterns, and lowly expressed isoforms, resulting in incomplete or inaccurate annotations. To overcome these limitations, we developed GSAman, a standalone, ready-to-use tool that enables intuitive, what-you-see-is-what-you-get (WYSIWYG) editing of gene-structure annotations. In contrast to web-based platforms such as Apollo2, which generally require server deployment and do not provide full offline functionality, GSAman delivers a fully local, responsive interface for real-time annotation refinement, thereby improving accessibility across research settings. GSAman supports both fine-scale curations of individual genes and large-scale annotation of entire genomes. By enabling precise curation of gene models across varied genomic contexts, it directly facilitates downstream applications, including pan-genome construction, gene family evolutionary analyses, and precision crop enhancement. Using a telomere-to-telomere rice genome (MH63) annotation project as a case study, we demonstrate the practical utility of GSAman in producing a complete and accurate reference annotation, improving Benchmarking Universal Single-Copy Orthologs (BUSCO) completeness to 99.63% following manual curation. We believe GSAman will serve as a critical resource for advancing functional genomics across diverse species.","PeriodicalId":36121,"journal":{"name":"The Innovation","volume":"7 10","pages":"101471"},"PeriodicalIF":39.5,"publicationDate":"2026-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13673535/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149216784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Artificial intelligence needs a common ruler. 人工智能需要一个共同的统治者。

IF 39.5 1区综合性期刊

The Innovation Pub Date : 2026-06-15 eCollection Date: 2026-08-03 DOI: 10.1016/j.xinn.2026.101473

Yang Zhao, Zhenfei Song, Pengyu Tan, Xingchuang Xiong, Xiang Fang

引用次数: 0

Electrochemical-mechanical-thermal modeling for lithium-ion batteries. 锂离子电池的电化学-机械-热建模。

IF 39.5 1区综合性期刊

The Innovation Pub Date : 2026-06-11 eCollection Date: 2026-10-05 DOI: 10.1016/j.xinn.2026.101472

Wenxin Mei, Zhixiang Cheng, Chenrui She, Chaoshi Liu, Jinhua Sun, Qingsong Wang

{"title":"Electrochemical-mechanical-thermal modeling for lithium-ion batteries.","authors":"Wenxin Mei, Zhixiang Cheng, Chenrui She, Chaoshi Liu, Jinhua Sun, Qingsong Wang","doi":"10.1016/j.xinn.2026.101472","DOIUrl":"10.1016/j.xinn.2026.101472","url":null,"abstract":"Lithium-ion battery operation results from multiphysical interactions incorporating electrochemical-mechanical-thermal interrelated processes taking place across diverse length/timescales. Driven by efficient and safe applications, understanding electrochemical-mechanical-thermal phenomena has become an overriding consideration for the prosperity of sustainable lithium-ion battery technology. Toward this goal, priority is given to modeling techniques because of comparatively satisfactory cost, identifying limited phenomena, and predicting how altering parameters affects the entire system. Herein, current advancements are evaluated and summarized in the realm to gain a comprehensive description of the electrochemical-mechanical-thermal modeling framework associated with the intricate interplay within electrochemical-mechanical-thermal properties. Electrochemical, mechanical, and thermal models are classified to characterize the corresponding properties during normal operation, degradation, and even thermal runaway. For convoluted and interconnected electrochemical-mechanical-thermal phenomena, initiating a unified modeling workflow intimately with a combination of question proposal, model development, parameter acquisition, model validation, and application is indispensable to unlocking the full investigative potential and assisting novices and specialists with model development. Finally, the future challenges confronted are discussed.","PeriodicalId":36121,"journal":{"name":"The Innovation","volume":"7 10","pages":"101472"},"PeriodicalIF":39.5,"publicationDate":"2026-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13673537/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149216769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Engineering trustworthy closed-loop bioelectronic systems for cardiovascular disease. 工程可靠的闭环生物电子系统心血管疾病。

IF 39.5 1区综合性期刊

The Innovation Pub Date : 2026-06-05 eCollection Date: 2026-08-03 DOI: 10.1016/j.xinn.2026.101468

Xiaofei Wang, Yinghan Wang, Chunxiao Wu, Shuyuan Zhang, Yi Lu, Zhuang Tian, Shuyang Zhang

引用次数: 0

Controlled analog Ising machine: An accelerated and accuracy-enhanced intelligent solver for edge computing. 受控模拟计算机：用于边缘计算的加速和精度增强的智能求解器。

IF 39.5 1区综合性期刊

The Innovation Pub Date : 2026-06-05 eCollection Date: 2026-07-06 DOI: 10.1016/j.xinn.2026.101466

Langyu Li, Yu Pan, Wei Wang, Jinhu Lü, Qing Gao

引用次数: 0

Flexible ultrafast spintronic terahertz emitter with exceptional working temperature range. 具有特殊工作温度范围的柔性超快自旋电子太赫兹发射器。

IF 39.5 1区综合性期刊

The Innovation Pub Date : 2026-06-04 eCollection Date: 2026-10-05 DOI: 10.1016/j.xinn.2026.101467

Piming Gong, Faran Zhou, Liguang Gong, Yu Cheng, Litong Jiang, Peiyan Li, Jian Song, Guoqing Chang, Jing Teng, Xiaojun Wu, Zhiming Wang, Jimin Zhao

{"title":"Flexible ultrafast spintronic terahertz emitter with exceptional working temperature range.","authors":"Piming Gong, Faran Zhou, Liguang Gong, Yu Cheng, Litong Jiang, Peiyan Li, Jian Song, Guoqing Chang, Jing Teng, Xiaojun Wu, Zhiming Wang, Jimin Zhao","doi":"10.1016/j.xinn.2026.101467","DOIUrl":"10.1016/j.xinn.2026.101467","url":null,"abstract":"Spintronic terahertz (THz) emitters (TEs) leverage the spin degree of freedom. To address the growing demand for flexible TEs, we demonstrate a soft spintronic ultrafast TE based on a NiFe/SrRuO3/SrTiO3/mica(substrate) heterostructure. It emits picosecond 0-4 THz waves under near-infrared laser excitation, driven by the inverse spin Hall effect. Bendable samples with largely tunable curvatures (-2 cm-1≤ κ ≤ 2 cm-1) are achieved, by which a maximum 82% enhancement in the THz field strength is observed. We attribute it to tensile strain-induced large spin-orbit torque in SrRuO3. Significantly, we demonstrate an 80-500 K working temperature range for this all-inorganic flexible device, enabling applications under unprecedented extreme conditions (e.g., on the Moon's surface or at the poles). Our work ushers in the dawn of extreme-temperature-environment, all-inorganic, wearable, and broadband ultrafast THz devices, which uncovers an unexplored area for the application of ultrafast THz photonics.","PeriodicalId":36121,"journal":{"name":"The Innovation","volume":"7 10","pages":"101467"},"PeriodicalIF":39.5,"publicationDate":"2026-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13673546/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149216843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

China's basic research trajectory: From scaling up to system building. 中国基础研究轨迹：从规模化到体系化。

IF 39.5 1区综合性期刊

The Innovation Pub Date : 2026-06-03 eCollection Date: 2026-09-08 DOI: 10.1016/j.xinn.2026.101461

引用次数: 0

Hierarchical bending microstructures in π-conjugated molecular cocrystals. π共轭分子共晶中的层次弯曲微结构。

IF 39.5 1区综合性期刊

The Innovation Pub Date : 2026-06-03 eCollection Date: 2026-07-06 DOI: 10.1016/j.xinn.2026.101464

Xinyu Du, Shuang Li, Lizhi Wang, Tingting Yang, Yong Zhang, Xuehua Ding, Jinyi Lin, Wei Huang

引用次数: 0

First achievement of high-confinement mode in proton-boron plasmas. 质子-硼等离子体中高约束模式的首次实现。

IF 39.5 1区综合性期刊

The Innovation Pub Date : 2026-06-03 eCollection Date: 2026-07-06 DOI: 10.1016/j.xinn.2026.101458

Yumin Wang, Yuejiang Shi, Dong Guo, Yihang Zhao, Guang Yang, Ao Wang, Hongyue Li, Shaodong Song, Ying Yuan, Xuxu Zhang, Xiang Gu, Cong Zhang, Jia Li, Songjian Li, Renyi Tao, Xianli Huang, Yupeng Zhang, Zhaokun Wang, Qifeng Xie, Lei Li, Lei Han, Xin Zhao, Huasheng Xie, Xianming Song, Jiaqi Dong, Y-K Martin Peng, Yunfeng Liang, Minsheng Liu

引用次数: 0

China's 2026 revision of National Ambient Air Quality Standards: A critical step toward health-based air pollution governance. 中国2026年修订《国家环境空气质量标准》：朝着以健康为基础的空气污染治理迈出的关键一步。

IF 39.5 1区综合性期刊

The Innovation Pub Date : 2026-06-03 eCollection Date: 2026-07-06 DOI: 10.1016/j.xinn.2026.101463

Jing Cai, Haidong Kan

引用次数: 0