The Innovation最新文献_第4页

Spectroscopic solutions for generating new global soil information. 用于生成新的全球土壤信息的光谱解决方案。

IF 33.2 1区综合性期刊

The Innovation Pub Date : 2025-02-13 eCollection Date: 2025-05-05 DOI: 10.1016/j.xinn.2025.100839

Yi Peng, Eyal Ben-Dor, Asim Biswas, Sabine Chabrillat, José A M Demattê, Yufeng Ge, Asa Gholizadeh, Cecile Gomez, Cesar Guerrero, Jeffrey Herrick, Jonathan J Maynard, Abdul Mounem Mouazen, Yuxin Ma, Alex B McBratney, Budiman Minasny, Leonardo Ramirez-Lopez, A H Jean Robertson, Raphael A Viscarra Rossel, Zhou Shi, Bo Stenberg, Alexandre M J-C Wadoux, Leigh Ann Winowiecki, Ganlin Zhang

{"title":"Spectroscopic solutions for generating new global soil information.","authors":"Yi Peng, Eyal Ben-Dor, Asim Biswas, Sabine Chabrillat, José A M Demattê, Yufeng Ge, Asa Gholizadeh, Cecile Gomez, Cesar Guerrero, Jeffrey Herrick, Jonathan J Maynard, Abdul Mounem Mouazen, Yuxin Ma, Alex B McBratney, Budiman Minasny, Leonardo Ramirez-Lopez, A H Jean Robertson, Raphael A Viscarra Rossel, Zhou Shi, Bo Stenberg, Alexandre M J-C Wadoux, Leigh Ann Winowiecki, Ganlin Zhang","doi":"10.1016/j.xinn.2025.100839","DOIUrl":"https://doi.org/10.1016/j.xinn.2025.100839","url":null,"abstract":"While global efforts to operationalize soil spectroscopy are progressing, cooperation is needed to fully leverage its potential for generating digital soil information to support sustainable soil management worldwide. The Global Soil Laboratory Network's soil spectroscopy initiative (GLOSOLAN-Spec), led by the Food and Agriculture Organization of the United Nations (FAO) through its Global Soil Partnership (GSP), is dedicated to the further development and adoption of soil spectroscopy by fostering international collaboration via a scientific community of practice to produce accurate and reliable soil information for sustainable soil management and decision-making. To support this effort, we, a global consortium of soil scientists under the auspices of the International Union of Soil Sciences (IUSS) and GLOSOLAN-Spec, aim to address seven key challenges hindering the adoption of soil spectroscopy worldwide. Here, we offer perspectives on what is needed to advance soil spectroscopy as a routine soil analysis method, emphasizing its potential to generate new and reliable spatial and temporal soil data.","PeriodicalId":36121,"journal":{"name":"The Innovation","volume":"6 5","pages":"100839"},"PeriodicalIF":33.2,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12105478/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144162635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Stereoscopic remote sensing observation for mountains: Advancing monitoring, modeling, and management. 山地立体遥感观测：推进监测、建模与管理。

IF 33.2 1区综合性期刊

The Innovation Pub Date : 2025-02-11 eCollection Date: 2025-05-05 DOI: 10.1016/j.xinn.2025.100838

Jinhu Bian, Ainong Li, Xi Nan, Zhengjian Zhang, Guangbin Lei, Jinping Zhao, Yi Deng, Xiaohan Lin, Limin Chen, Amin Naboureh

引用次数: 0

The inadequacy of the ρ-T curve for phase transitions in the presence of magnetic fields. 在磁场存在下，ρ-T曲线的相变是不充分的。

IF 33.2 1区综合性期刊

The Innovation Pub Date : 2025-02-10 eCollection Date: 2025-05-05 DOI: 10.1016/j.xinn.2025.100837

Shengnan Zhang, Zhong Fang, Hongming Weng, Quansheng Wu

{"title":"The inadequacy of the ρ-T curve for phase transitions in the presence of magnetic fields.","authors":"Shengnan Zhang, Zhong Fang, Hongming Weng, Quansheng Wu","doi":"10.1016/j.xinn.2025.100837","DOIUrl":"10.1016/j.xinn.2025.100837","url":null,"abstract":"The resistivity-temperature (ρ(T)) curve is traditionally employed to distinguish metallic, semiconducting, and insulating behaviors in materials, with deviations often interpreted as evidence of phase transitions. However, such interpretations are valid only under specific conditions, including the presence of a magnetic field. This study critically reexamines the ρ(T) curve in magnetic environments. Our findings reveal that shifts between metallic and insulating states, as well as reentrant metallic behavior, may not necessarily indicate genuine phase transitions. Instead, these phenomena can be attributed to the scaling behavior of magnetoresistance, governed by a power law dependence on both the magnetic field and temperature. Employing first-principles calculations and the Boltzmann transport method, we analyzed the magnetoresistance of SiP2 and NbP across varying conditions. This approach not only explains the reentrant behavior observed experimentally but also reconciles discrepancies in magnetoresistance findings reported by different research groups. These findings challenge the conventional reliance on the ρ(T) curve as a straightforward indicator of phase transitions in magnetic fields. We underscore the importance of accounting for standard magnetoresistance effects caused by the Lorentz force before confirming the existence of such transitions. This novel perspective advances our understanding of material properties in magnetic fields and establishes a new framework for interpreting transport phenomena in condensed matter physics.","PeriodicalId":36121,"journal":{"name":"The Innovation","volume":"6 5","pages":"100837"},"PeriodicalIF":33.2,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12105513/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144162649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ozone exposure and increased risk of age-related macular degeneration: Evidence from nationwide cohort and toxicological studies. 臭氧暴露和年龄相关性黄斑变性风险增加：来自全国队列和毒理学研究的证据。

IF 33.2 1区综合性期刊

The Innovation Pub Date : 2025-02-10 eCollection Date: 2025-04-07 DOI: 10.1016/j.xinn.2025.100808

Guanran Zhang, Yanlin Qu, Xiaoling Wan, Xinyi Fang, Yidong Wu, Tong Li, Junran Sun, Xinxin Liu, Yanyi Xu, Huihuan Luo, Xia Meng, Weiting Hu, Renjie Chen, Zhenyu Wu, Huixun Jia, Xiaodong Sun

{"title":"Ozone exposure and increased risk of age-related macular degeneration: Evidence from nationwide cohort and toxicological studies.","authors":"Guanran Zhang, Yanlin Qu, Xiaoling Wan, Xinyi Fang, Yidong Wu, Tong Li, Junran Sun, Xinxin Liu, Yanyi Xu, Huihuan Luo, Xia Meng, Weiting Hu, Renjie Chen, Zhenyu Wu, Huixun Jia, Xiaodong Sun","doi":"10.1016/j.xinn.2025.100808","DOIUrl":"10.1016/j.xinn.2025.100808","url":null,"abstract":"Evidence regarding the impact of ozone on age-related macular degeneration (AMD) remains limited. We conducted a nationwide cohort analysis of 27,923 participants in China, along with a random control animal toxicological study, to elucidate the temporal relationship between ozone exposure and AMD as well as the underlying biological explanation. In the population study, 5,149 participants were diagnosed with incident AMD during a 348,701 person-month follow-up. The participants were divided into low-, medium-, and high-exposure groups. Fully adjusted Cox regression models showed that the risk of AMD increased by 28% for the medium- and 101% for the high-exposure groups relative to the low-exposure group (p for trend < 0.001). The exposure-response curves exhibited a J-shaped trend. Sensitivity analyses confirmed these results, revealing stronger associations among participants older than 65 years old and those living in rural or northern China. In the toxicological study, the mice were randomized to inhale ozone or filtered air, and those exposed to ozone had photoreceptor damage and vision impairment, which are hallmarks of AMD. We further clarified that ozone exposure contributes to AMD by activating systemic inflammation and detailing how external air-pollutant-induced inflammation factors reach the retina, which is the innermost layer of the eye, and cause retinal disease. Our comprehensive studies provide key evidence on the temporal relationship between ozone exposure and increased AMD risk, suggesting the visual health benefits of collaboratively enforcing necessary ozone pollution control policies, especially in regions with high ozone concentrations, within the context of a globally aging population.","PeriodicalId":36121,"journal":{"name":"The Innovation","volume":"6 4","pages":"100808"},"PeriodicalIF":33.2,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12131036/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144226931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

From primary forests to rubber plantations: A huge ecological loss. 从原始森林到橡胶种植园：巨大的生态损失。

IF 33.2 1区综合性期刊

The Innovation Pub Date : 2025-02-07 eCollection Date: 2025-05-05 DOI: 10.1016/j.xinn.2025.100836

Yuxi Wang, Lin Zhang

引用次数: 0

Erratum: Fast reconstruction and optical-sectioning three-dimensional structured illumination microscopy. 勘误：快速重建和光学切片三维结构照明显微镜。

IF 33.2 1区综合性期刊

The Innovation Pub Date : 2025-02-06 eCollection Date: 2025-03-03 DOI: 10.1016/j.xinn.2025.100812

Ruijie Cao, Yaning Li, Wenyi Wang, Yunzhe Fu, Xiaoyu Bu, Dilizhatai Saimi, Jing Sun, Xichuan Ge, Shan Jiang, Yuru Pei, Baoxiang Gao, Zhixing Chen, Meiqi Li, Peng Xi

引用次数: 0

The rising threats of wildland-urban interface fires in the era of climate change: The Los Angeles 2025 fires. 气候变化时代，荒地-城市交界面火灾的威胁日益增加：洛杉矶2025年火灾。

IF 33.2 1区综合性期刊

The Innovation Pub Date : 2025-02-04 eCollection Date: 2025-05-05 DOI: 10.1016/j.xinn.2025.100835

Minghao Qiu, Deyang Chen, Makoto Kelp, Jing Li, Guanyu Huang, Mahdieh Danesh Yazdi

引用次数: 0

Toward more economical large-scale foundation models: No longer a game for the few. 走向更经济的大规模基础模型：不再是少数人的游戏。

IF 33.2 1区综合性期刊

The Innovation Pub Date : 2025-01-30 eCollection Date: 2025-04-07 DOI: 10.1016/j.xinn.2025.100832

Yiqing Wu, Zhao Zhang, Fei Wang, Yongjun Xu, Jincai Huang

引用次数: 0

Novel cancer stem cell-targeted retinoid ZSH-512 impedes colorectal cancer progress via KDM3A-mediated epigenetic reprogramming. 新型癌症干细胞靶向类维甲酸ZSH-512通过kdm3a介导的表观遗传重编程阻碍结直肠癌的进展。

IF 33.2 1区综合性期刊

The Innovation Pub Date : 2025-01-30 eCollection Date: 2025-04-07 DOI: 10.1016/j.xinn.2025.100831

Suyao Li, Wenrui Zhao, Quanlin An, Lei Wang, Mengxuan Zhu, Junjie Ni, Xuan Huang, Yudong Jiang, Min Li, Jiayun Hou, Yiyi Yu, Shan Yu, Lai Wei, Heng Jiao, Tianshu Liu, Xin Cao

{"title":"Novel cancer stem cell-targeted retinoid ZSH-512 impedes colorectal cancer progress via KDM3A-mediated epigenetic reprogramming.","authors":"Suyao Li, Wenrui Zhao, Quanlin An, Lei Wang, Mengxuan Zhu, Junjie Ni, Xuan Huang, Yudong Jiang, Min Li, Jiayun Hou, Yiyi Yu, Shan Yu, Lai Wei, Heng Jiao, Tianshu Liu, Xin Cao","doi":"10.1016/j.xinn.2025.100831","DOIUrl":"10.1016/j.xinn.2025.100831","url":null,"abstract":"Advanced colorectal cancer (CRC) exhibits weak responses to multiple therapies, primarily due to the presence of cancer stem cells (CSCs), which drive high recurrence rates, metastasis, and drug resistance. We have previously systematically conducted CSC-targeted compound discovery and evaluation studies to inhibit CSC-mediated tumorigenesis and metastasis. Here, we identified ZSH-512, a novel synthetic retinoid that selectively targets retinoic acid receptor (RAR)γ, demonstrating its ability to effectively inhibit CRC-CSCs and patient-derived organoids (PDOs) in vitro and significantly reduce CSC-mediated tumor formation and liver metastasis in mouse models without noticeable toxicity. Mechanistically, integrated analysis of Assay for Transposase-Accessible Chromatin sequencing (ATAC-seq) and RNA sequencing (RNA-seq) revealed that ZSH-512 exerted its effect by modulating the RARγ-KDM3A axis to mediate epigenetic reprogramming and broadly suppress stemness-related signaling pathways, including Wnt, Hippo, and Hedgehog. ZSH-512 efficiently inhibited tumorigenesis in CRC-patient-derived tumor xenografts (PDXs) with high KDM3A expression, suggesting KDM3A as a potential predictive biomarker. Collectively, ZSH-512 is a promising therapeutic candidate for targeting CRC-CSCs with high efficacy.","PeriodicalId":36121,"journal":{"name":"The Innovation","volume":"6 4","pages":"100831"},"PeriodicalIF":33.2,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12130993/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144226929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Artificial intelligence facilitates information fusion for perception in complex environments. 人工智能促进了复杂环境中感知的信息融合。

IF 33.2 1区综合性期刊

The Innovation Pub Date : 2025-01-29 eCollection Date: 2025-04-07 DOI: 10.1016/j.xinn.2025.100814

Xunpeng Yi, Yong Ma, Yansheng Li, Han Xu, Jiayi Ma

引用次数: 0