{"title":"Glass scintillator: A window to future high-energy radiation detection.","authors":"Zexuan Sui, Sen Qian, Luyue Niu, Peng Hu, Zhehao Hua, Xiaoxin Zheng, Xinyuan Sun, Gao Tang, Hua Cai, Dong Yang, Weichang Li, Minghui Zhang, Jifeng Han, Jing Ren","doi":"10.1016/j.xinn.2025.100878","DOIUrl":"10.1016/j.xinn.2025.100878","url":null,"abstract":"<p><p>With the significant progress of high-energy physics, nuclear science, and technology, the demand for high-performance scintillators is growing rapidly. Among solid-state scintillators, glass scintillators would play a vital role in the field of high-energy radiation detections because of their merits including low cost, batch production, and arbitrariness in shape. In this review article, the research and development of glass scintillators is introduced with respect to the following key parameters including: density, light yield, scintillation decay time, and radiation hardness. The scintillation mechanisms, preparation methods particularly for Ce<sup>3+</sup>-activated glasses, standard testing methods, scintillation performance, and applications of glass scintillators are comprehensively reviewed and critically discussed. Finally, the problems existing in the research field are presented and the future development directions of glass scintillators for performance improvement are suggested.</p>","PeriodicalId":36121,"journal":{"name":"The Innovation","volume":"6 5","pages":"100878"},"PeriodicalIF":33.2,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12105494/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144162569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Multi-bioinspired electronic skins with on-demand adhesion and opto-electronic synergistic display capabilities.","authors":"Wenzhao Li, Jinbo Li, Xiaoya Ding, Qitao Tan, Weijian Sun, Puxiang Lai, Yuanjin Zhao","doi":"10.1016/j.xinn.2025.100877","DOIUrl":"10.1016/j.xinn.2025.100877","url":null,"abstract":"<p><p>Flexible electronic skins hold great promise for biomedical applications, although challenges remain in achieving controllable interactions with the biological interface and accurate signal collection. Inspired by octopuses and chameleons, we propose a novel electronic skin paradigm with on-demand adhesion and opto-electronic synergistic display capabilities. Our electronic skins are composed of a stretchable polyurethane (PU) inverse opal film integrated with a carbon nanotube (CNT)-hybridized polyacrylamide (PAAm)-gelatin double-network-hydrogel conductive flexible substrate and a temperature-responsive poly(N-isopropylacrylamide) (PNIPAm) octopus-inspired hemispherical adhesive array. The device's CNT hybrid double-network provides robust and sensitive monitoring of temperature and motion. Meanwhile, its flexible PU layer with an inverse opal structure allows for visual motion color sensing. Integrated neural network processing ensures accurate, wide-range, and independent multimodal display. Additionally, the integration of the photothermal effect of CNTs and the temperature-sensitive octopus-inspired PNIPAm adhesive array enables on-demand adhesion. The sensing and adhesion demonstrations <i>ex vivo</i> and <i>in vivo</i> showcase the proposed flexible electronic skin's inspirational design and functional utilities. The potential applications of such a versatile device are vast, ranging from healthcare to human-machine interactions.</p>","PeriodicalId":36121,"journal":{"name":"The Innovation","volume":"6 5","pages":"100877"},"PeriodicalIF":33.2,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12105526/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144162592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The InnovationPub Date : 2025-03-11eCollection Date: 2025-06-02DOI: 10.1016/j.xinn.2025.100874
Qinglong Wang, Fangling Zhao, Ben Wang, Kai Fung Chan, Bonaventure Yiu Ming Ip, Thomas Wai Hong Leung, Xin Song, Li Zhang, Jue Xie
{"title":"Untethered miniature robots for minimally invasive thrombus treatment: From bench to clinical trials.","authors":"Qinglong Wang, Fangling Zhao, Ben Wang, Kai Fung Chan, Bonaventure Yiu Ming Ip, Thomas Wai Hong Leung, Xin Song, Li Zhang, Jue Xie","doi":"10.1016/j.xinn.2025.100874","DOIUrl":"10.1016/j.xinn.2025.100874","url":null,"abstract":"<p><p>Untethered miniature robots (MRs) offer a minimally invasive way to address adverse vascular blockages, such as cerebrovascular thromboembolism, myocardial infarction, and pulmonary embolism. This review explores three key questions: what are the design principles of MRs from both engineering and clinical perspectives? How can visible intervention of MRs in three-dimensional (3D) branched vessels be achieved? What is the clinical procedure for treating thrombus using designed MRs? Recent progress in MRs for thrombus removal is summarized, and, more importantly, the pros and cons of MRs are discussed. We also evaluate the challenges that may hinder their clinical deployment and propose future research directions, bridging the gap between the bench and the bedside.</p>","PeriodicalId":36121,"journal":{"name":"The Innovation","volume":"6 6","pages":"100874"},"PeriodicalIF":33.2,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12169274/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144318202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Contrasting temporal dynamics of land surface temperature responses to different types of forest loss.","authors":"Jing Li, Zhao-Liang Li, Xiangyang Liu, Yitao Li, Meng Liu, Nanshan You, Hua Wu, Lei He, Menglin Si, Ronglin Tang, Chenghu Zhou, Wei Zhao, Si-Bo Duan, Pei Leng, Wenqi Liu, Enyu Zhao, Bo-Hui Tang, Zhenong Jin","doi":"10.1016/j.xinn.2025.100875","DOIUrl":"10.1016/j.xinn.2025.100875","url":null,"abstract":"<p><p>Forest loss impacts local climate through biophysical processes. However, our understanding of this impact remains limited due to the neglect of its temporal dynamics. Using a space-and-time scheme that incorporates a change-detection method, we assess the dynamics of land surface temperature (LST) responses to various forest-loss types. Globally, LST increased by 0.12 K one year after forest loss, followed by a decreasing trend of -0.14 K per decade. Deforestation driven by commodity production and urbanization results in persistent warming, while forest disturbances such as shifting agriculture, forestry, and fire trigger diverse response dynamics with significant spatial variation due to differences in subsequent vegetation recovery. These disturbances cause attenuated warming in low and mid-latitudes, while, in the boreal zone, contrasting dynamics are observed: shifting agriculture causes attenuated cooling, whereas forestry and fire result in enhanced cooling. In addition to amplifying the amplitude of the LST seasonal cycle, forest loss also shifts the seasonal phase, which has not been previously reported. These findings demonstrate that climate feedback from forest loss is climate specific, loss-type dependent, and time varying, providing new insights for the development of local climate policies.</p>","PeriodicalId":36121,"journal":{"name":"The Innovation","volume":"6 6","pages":"100875"},"PeriodicalIF":33.2,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12169273/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144318187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The InnovationPub Date : 2025-03-11eCollection Date: 2025-07-07DOI: 10.1016/j.xinn.2025.100873
Jianxiao Wang, Xinjiang Chen, Minghao Zhuang, Yan Li, Ziwen Ruan, Yuhan Wang, Ning Zhang, Jie Song, Kebin He, Xi Lu
{"title":"Accelerating exploitation and integration of global renewable energy.","authors":"Jianxiao Wang, Xinjiang Chen, Minghao Zhuang, Yan Li, Ziwen Ruan, Yuhan Wang, Ning Zhang, Jie Song, Kebin He, Xi Lu","doi":"10.1016/j.xinn.2025.100873","DOIUrl":"https://doi.org/10.1016/j.xinn.2025.100873","url":null,"abstract":"","PeriodicalId":36121,"journal":{"name":"The Innovation","volume":"6 7","pages":"100873"},"PeriodicalIF":33.2,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12277708/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144691824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The InnovationPub Date : 2025-03-07eCollection Date: 2025-05-05DOI: 10.1016/j.xinn.2025.100870
Tingting Ye, Rongbin Xu, Wenzhong Huang, Zhengyu Yang, Pei Yu, Wenhua Yu, Yanming Liu, Yao Wu, Bo Wen, Yiwen Zhang, Jaime E Hart, Mark Nieuwenhuijsen, Michael J Abramson, Yuming Guo, Shanshan Li
{"title":"Billions of people exposed to increasing heat but decreasing greenness from 2000 to 2022.","authors":"Tingting Ye, Rongbin Xu, Wenzhong Huang, Zhengyu Yang, Pei Yu, Wenhua Yu, Yanming Liu, Yao Wu, Bo Wen, Yiwen Zhang, Jaime E Hart, Mark Nieuwenhuijsen, Michael J Abramson, Yuming Guo, Shanshan Li","doi":"10.1016/j.xinn.2025.100870","DOIUrl":"10.1016/j.xinn.2025.100870","url":null,"abstract":"<p><p>Rising heat stress due to climate warming poses a significant threat to human health, and greenness offers a nature-based solution to mitigate heat-related health impacts and enhance resilience. Although global greenness has increased, it remains unclear whether these trends align with the population's heat mitigation needs. In this study, we integrated spatially resolved demographic data with satellite-derived greenness metric and reanalysis-based heat stress data to construct a global profile of joint exposure at 1 × 1 km resolution from 2000 to 2022. We found that 69.3% of global populated areas and 41.3% of the global population (∼2.9 billion people) were exposed to increasing heat stress but decreasing greenness (IHDG), representing the most concerning situation for heat mitigation. Urban populations were disproportionately affected, with 50.8% exposed compared to 27.1% in rural areas. Low- and middle-income countries exhibited more pronounced trends of increasing heat stress and bore the greatest burden from IHDG, accounting for 85% of total exposed populations. Moreover, there was a notable demographic shift in IHDG-exposed populations toward older groups, exacerbating the heat mitigation crisis. This study advances the understanding of the joint dynamics of heat stress and greenness and provides a profile of population exposure at a fine grid level. By highlighting the scale of IHDG conditions, our findings emphasize the urgent need to address this environmental challenge and a significant opportunity for improving greenness to mitigate increasing heat globally. The spatially detailed assessment maps offer essential data for informed decision-making.</p>","PeriodicalId":36121,"journal":{"name":"The Innovation","volume":"6 5","pages":"100870"},"PeriodicalIF":33.2,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12105507/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144162558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The InnovationPub Date : 2025-03-07eCollection Date: 2025-06-02DOI: 10.1016/j.xinn.2025.100871
Lijuan Liu, Fan Wang, Lei Wang, Xinglin Jiang, Haibo Zhang
{"title":"Addressing challenges in microbial manufacturing: Systematic microbial biotechnology.","authors":"Lijuan Liu, Fan Wang, Lei Wang, Xinglin Jiang, Haibo Zhang","doi":"10.1016/j.xinn.2025.100871","DOIUrl":"10.1016/j.xinn.2025.100871","url":null,"abstract":"<p><p>Microbial manufacturing offers an alternative approach to producing chemicals and materials in a sustainable and environmentally friendly manner. Despite its significance and widespread attention, various challenges persist in its industrial application. We propose a systematic approach to microbial biotechnology-a comprehensive framework for developing customized technologies tailored to the unique characteristics of the entire process for specific products. It utilizes approaches such as simplifying the process, sequential rearrangement, and coupling steps to systematically and holistically address the bottlenecks of the entire process in microbial manufacturing, aiming to achieve optimal economic and environmental benefits. This method involves the integration of multiple disciplines, including enzymology, synthetic biology, metabolic engineering, fermentation, separation engineering, and artificial intelligence (AI) technology. Here, we present several cases involving various stages of product bioproduction, developed under the concept of systematic microbial biotechnology, to demonstrate its effectiveness and advantages. The development and application of these technological concepts hold significant potential to shape the future of a sustainable circular bioeconomy driven by microbial manufacturing.</p>","PeriodicalId":36121,"journal":{"name":"The Innovation","volume":"6 6","pages":"100871"},"PeriodicalIF":33.2,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12169249/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144318185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}