The Innovation最新文献_第2页

Thalamic burst and tonic firing selectively indicate patients' consciousness level and recovery. 丘脑爆发和强直性放电选择性地指示患者的意识水平和恢复情况。

IF 33.2 1区综合性期刊

The Innovation Pub Date : 2025-02-25 eCollection Date: 2025-05-05 DOI: 10.1016/j.xinn.2025.100846

Huan Wang, Yongxiang Hu, Qianqian Ge, Yuanyuan Dang, Yi Yang, Long Xu, Xiaoyu Xia, Peng Zhang, Sheng He, Steven Laureys, Yan Yang, Jianghong He

{"title":"Thalamic burst and tonic firing selectively indicate patients' consciousness level and recovery.","authors":"Huan Wang, Yongxiang Hu, Qianqian Ge, Yuanyuan Dang, Yi Yang, Long Xu, Xiaoyu Xia, Peng Zhang, Sheng He, Steven Laureys, Yan Yang, Jianghong He","doi":"10.1016/j.xinn.2025.100846","DOIUrl":"10.1016/j.xinn.2025.100846","url":null,"abstract":"Patients with disorders of consciousness suffer from severe impairments in arousal and awareness alongside anomalous brain connections and aberrant neuronal activities. The thalamus, a crucial hub in the brain connectome, has been empirically inferred to maintain consciousness and wakefulness. Here, we investigated thalamic spiking, brain connectivity, consciousness states, and recovery outcomes following deep brain stimulation in 29 patients. Our study reveals that thalamic neuronal activity serves as a marker of consciousness state. Patients diagnosed with vegetative state/unresponsive wakefulness syndrome exhibited less-active neurons, with longer and more variable burst discharges, than those in a minimally conscious state. Furthermore, neuronal profiles in the intralaminar thalamus, the direct stimulation site, predicted whether electrostimulation here improved recovery. Stronger tonic firing was correlated with enhanced thalamocortical connectivity and better recovery outcomes in patients. These findings suggest that thalamic spiking signatures, including single-neuron burst discharge and tonic firing, selectively indicate the representation and alteration of consciousness.","PeriodicalId":36121,"journal":{"name":"The Innovation","volume":"6 5","pages":"100846"},"PeriodicalIF":33.2,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12105493/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144162644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Spectroscopic solutions for generating new global soil information. 用于生成新的全球土壤信息的光谱解决方案。

IF 33.2 1区综合性期刊

The Innovation Pub Date : 2025-02-13 eCollection Date: 2025-05-05 DOI: 10.1016/j.xinn.2025.100839

Yi Peng, Eyal Ben-Dor, Asim Biswas, Sabine Chabrillat, José A M Demattê, Yufeng Ge, Asa Gholizadeh, Cecile Gomez, Cesar Guerrero, Jeffrey Herrick, Jonathan J Maynard, Abdul Mounem Mouazen, Yuxin Ma, Alex B McBratney, Budiman Minasny, Leonardo Ramirez-Lopez, A H Jean Robertson, Raphael A Viscarra Rossel, Zhou Shi, Bo Stenberg, Alexandre M J-C Wadoux, Leigh Ann Winowiecki, Ganlin Zhang

{"title":"Spectroscopic solutions for generating new global soil information.","authors":"Yi Peng, Eyal Ben-Dor, Asim Biswas, Sabine Chabrillat, José A M Demattê, Yufeng Ge, Asa Gholizadeh, Cecile Gomez, Cesar Guerrero, Jeffrey Herrick, Jonathan J Maynard, Abdul Mounem Mouazen, Yuxin Ma, Alex B McBratney, Budiman Minasny, Leonardo Ramirez-Lopez, A H Jean Robertson, Raphael A Viscarra Rossel, Zhou Shi, Bo Stenberg, Alexandre M J-C Wadoux, Leigh Ann Winowiecki, Ganlin Zhang","doi":"10.1016/j.xinn.2025.100839","DOIUrl":"https://doi.org/10.1016/j.xinn.2025.100839","url":null,"abstract":"While global efforts to operationalize soil spectroscopy are progressing, cooperation is needed to fully leverage its potential for generating digital soil information to support sustainable soil management worldwide. The Global Soil Laboratory Network's soil spectroscopy initiative (GLOSOLAN-Spec), led by the Food and Agriculture Organization of the United Nations (FAO) through its Global Soil Partnership (GSP), is dedicated to the further development and adoption of soil spectroscopy by fostering international collaboration via a scientific community of practice to produce accurate and reliable soil information for sustainable soil management and decision-making. To support this effort, we, a global consortium of soil scientists under the auspices of the International Union of Soil Sciences (IUSS) and GLOSOLAN-Spec, aim to address seven key challenges hindering the adoption of soil spectroscopy worldwide. Here, we offer perspectives on what is needed to advance soil spectroscopy as a routine soil analysis method, emphasizing its potential to generate new and reliable spatial and temporal soil data.","PeriodicalId":36121,"journal":{"name":"The Innovation","volume":"6 5","pages":"100839"},"PeriodicalIF":33.2,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12105478/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144162635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Stereoscopic remote sensing observation for mountains: Advancing monitoring, modeling, and management. 山地立体遥感观测：推进监测、建模与管理。

IF 33.2 1区综合性期刊

The Innovation Pub Date : 2025-02-11 eCollection Date: 2025-05-05 DOI: 10.1016/j.xinn.2025.100838

Jinhu Bian, Ainong Li, Xi Nan, Zhengjian Zhang, Guangbin Lei, Jinping Zhao, Yi Deng, Xiaohan Lin, Limin Chen, Amin Naboureh

引用次数: 0

The inadequacy of the ρ-T curve for phase transitions in the presence of magnetic fields. 在磁场存在下，ρ-T曲线的相变是不充分的。

IF 33.2 1区综合性期刊

The Innovation Pub Date : 2025-02-10 eCollection Date: 2025-05-05 DOI: 10.1016/j.xinn.2025.100837

Shengnan Zhang, Zhong Fang, Hongming Weng, Quansheng Wu

{"title":"The inadequacy of the ρ-T curve for phase transitions in the presence of magnetic fields.","authors":"Shengnan Zhang, Zhong Fang, Hongming Weng, Quansheng Wu","doi":"10.1016/j.xinn.2025.100837","DOIUrl":"10.1016/j.xinn.2025.100837","url":null,"abstract":"The resistivity-temperature (ρ(T)) curve is traditionally employed to distinguish metallic, semiconducting, and insulating behaviors in materials, with deviations often interpreted as evidence of phase transitions. However, such interpretations are valid only under specific conditions, including the presence of a magnetic field. This study critically reexamines the ρ(T) curve in magnetic environments. Our findings reveal that shifts between metallic and insulating states, as well as reentrant metallic behavior, may not necessarily indicate genuine phase transitions. Instead, these phenomena can be attributed to the scaling behavior of magnetoresistance, governed by a power law dependence on both the magnetic field and temperature. Employing first-principles calculations and the Boltzmann transport method, we analyzed the magnetoresistance of SiP2 and NbP across varying conditions. This approach not only explains the reentrant behavior observed experimentally but also reconciles discrepancies in magnetoresistance findings reported by different research groups. These findings challenge the conventional reliance on the ρ(T) curve as a straightforward indicator of phase transitions in magnetic fields. We underscore the importance of accounting for standard magnetoresistance effects caused by the Lorentz force before confirming the existence of such transitions. This novel perspective advances our understanding of material properties in magnetic fields and establishes a new framework for interpreting transport phenomena in condensed matter physics.","PeriodicalId":36121,"journal":{"name":"The Innovation","volume":"6 5","pages":"100837"},"PeriodicalIF":33.2,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12105513/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144162649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

From primary forests to rubber plantations: A huge ecological loss. 从原始森林到橡胶种植园：巨大的生态损失。

IF 33.2 1区综合性期刊

The Innovation Pub Date : 2025-02-07 eCollection Date: 2025-05-05 DOI: 10.1016/j.xinn.2025.100836

Yuxi Wang, Lin Zhang

引用次数: 0

Erratum: Fast reconstruction and optical-sectioning three-dimensional structured illumination microscopy. 勘误：快速重建和光学切片三维结构照明显微镜。

IF 33.2 1区综合性期刊

The Innovation Pub Date : 2025-02-06 eCollection Date: 2025-03-03 DOI: 10.1016/j.xinn.2025.100812

Ruijie Cao, Yaning Li, Wenyi Wang, Yunzhe Fu, Xiaoyu Bu, Dilizhatai Saimi, Jing Sun, Xichuan Ge, Shan Jiang, Yuru Pei, Baoxiang Gao, Zhixing Chen, Meiqi Li, Peng Xi

引用次数: 0

The rising threats of wildland-urban interface fires in the era of climate change: The Los Angeles 2025 fires. 气候变化时代，荒地-城市交界面火灾的威胁日益增加：洛杉矶2025年火灾。

IF 33.2 1区综合性期刊

The Innovation Pub Date : 2025-02-04 eCollection Date: 2025-05-05 DOI: 10.1016/j.xinn.2025.100835

Minghao Qiu, Deyang Chen, Makoto Kelp, Jing Li, Guanyu Huang, Mahdieh Danesh Yazdi

引用次数: 0

Manipulation of a strigolactone transporter in tomato confers resistance to the parasitic weed broomrape. 操纵番茄中独角孤内酯转运体赋予对寄生杂草扫帚花的抗性。

IF 33.2 1区综合性期刊

The Innovation Pub Date : 2025-01-29 eCollection Date: 2025-03-03 DOI: 10.1016/j.xinn.2025.100815

Xinwei Ban, Li Qin, Jijun Yan, Jianxin Wu, Qianjin Li, Xiao Su, Yanrong Hao, Qingliang Hu, Liquan Kou, Zongyun Yan, Peiyong Xin, Yuqin Zhang, Lemeng Dong, Harro Bouwmeester, Hong Yu, Qinghui Yu, Sanwen Huang, Tao Lin, Qi Xie, Yuhang Chen, Jinfang Chu, Xia Cui, Jiayang Li, Bing Wang

{"title":"Manipulation of a strigolactone transporter in tomato confers resistance to the parasitic weed broomrape.","authors":"Xinwei Ban, Li Qin, Jijun Yan, Jianxin Wu, Qianjin Li, Xiao Su, Yanrong Hao, Qingliang Hu, Liquan Kou, Zongyun Yan, Peiyong Xin, Yuqin Zhang, Lemeng Dong, Harro Bouwmeester, Hong Yu, Qinghui Yu, Sanwen Huang, Tao Lin, Qi Xie, Yuhang Chen, Jinfang Chu, Xia Cui, Jiayang Li, Bing Wang","doi":"10.1016/j.xinn.2025.100815","DOIUrl":"10.1016/j.xinn.2025.100815","url":null,"abstract":"Parasitic weeds of the Orobanchaceae family cause substantial economic losses and pose significant threats to global agriculture. However, management of such parasitism is challenging, and very few resistance genes have been cloned and characterized in depth. Here, we performed a genome-wide association study using 152 tomato accessions and identified SlABCG45 as a key gene that mediates host resistance to Phelipanche aegyptiaca by affecting the level of strigolactones (SLs) in root exudates. SLs are synthesized and released by host plants and act as germination stimulants for parasitic weeds. We found that SlABCG45 and its close homolog SlABCG44 were membrane-localized SL transporters with essential roles in exudation of SLs to the rhizosphere, resistance to Phelipanche and Orobanche, and upward transport of SLs from roots to shoots. As a predominant environmental stimulant exacerbates parasitism, phosphorus deficiency dramatically induced SlABCG45 expression and weakly induced SlABCG44 expression via the transcription factors SlNSP1 and SlNSP2. Knockout of SlABCG45 in tomato had little effect on yield traits in a broomrape-free field, but conferred increased resistance to different Phelipanche and Orobanche species, resulting in an ∼30% yield increase in a Phelipanche-infested field. Our findings reveal that targeting a single gene by genome editing can confer broad-spectrum parasite resistance in tomato, providing an effective strategy for the sustainable control of parasitic plants in agriculture.","PeriodicalId":36121,"journal":{"name":"The Innovation","volume":"6 3","pages":"100815"},"PeriodicalIF":33.2,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11910882/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143651109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Self-calibrating multiplexed microneedle electrode array for continuous mapping of subcutaneous multi-analytes in diabetes. 用于糖尿病皮下多种分析物连续测绘的自校准多路微针电极阵列。

IF 33.2 1区综合性期刊

The Innovation Pub Date : 2025-01-25 eCollection Date: 2025-02-03 DOI: 10.1016/j.xinn.2024.100781

Xiangling Li, Shantao Zheng, Mengyi He, Xinshuo Huang, Cheng Yang, Jingshan Mo, Jingbo Yang, Chengduan Yang, Huijiuan Chen, Xi Xie

{"title":"Self-calibrating multiplexed microneedle electrode array for continuous mapping of subcutaneous multi-analytes in diabetes.","authors":"Xiangling Li, Shantao Zheng, Mengyi He, Xinshuo Huang, Cheng Yang, Jingshan Mo, Jingbo Yang, Chengduan Yang, Huijiuan Chen, Xi Xie","doi":"10.1016/j.xinn.2024.100781","DOIUrl":"10.1016/j.xinn.2024.100781","url":null,"abstract":"Monitoring multiplexed biochemical markers is beneficial for the comprehensive evaluation of diabetes-associated complications. Techniques for multiplexed analyses in interstitial fluids have often been restricted by the difficulties of electrode materials in accurately detecting chemicals in complex subcutaneous spaces. In particular, the signal stability of enzyme-based sensing electrodes often inevitably decreases due to enzyme degradation or interference in vivo. In this study, we developed a self-calibrating multiplexed microneedle (MN) electrode array (SC-MMNEA) capable of continuous, real-time monitoring of multiple types of bioanalytes (glucose, cholesterol, uric acid, lactate, reactive oxygen species [ROSs], Na+, K+, Ca2+, and pH) in the subcutaneous space. Each type of analyte was detected by a discrete MN electrode assembled in an integrated array with single-MN resolution. Moreover, this device utilized an MN-delivery-mediated self-calibration technique to address the inherent problem of decreased accuracy of implantable electrodes caused by long-term tissue variation and enzyme degradation, and this technique might increase the reliability of the MN sensors. Our results indicated that SC-MMNEA could provide real-time monitoring of multiplexed analyte concentrations in a rat model with good accuracy, especially after self-calibration. SC-MMNEA has the advantages of in situ and minimally invasive monitoring of physiological states and the potential to promote wearable devices for long-term monitoring of chemical species in vivo.","PeriodicalId":36121,"journal":{"name":"The Innovation","volume":"6 2","pages":"100781"},"PeriodicalIF":33.2,"publicationDate":"2025-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11846035/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143484485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The rise of single-atom catalysts in hematite photoanodes for photoelectrochemical water splitting. 赤铁矿光阳极中单原子催化剂在光电化学水分解中的应用。

IF 33.2 1区综合性期刊

The Innovation Pub Date : 2025-01-23 eCollection Date: 2025-05-05 DOI: 10.1016/j.xinn.2025.100810

Peng-Yi Tang, Jordi Arbiol

引用次数: 0