Indian Pacing and Electrophysiology Journal最新文献

{"title":"Short coupled Ventricular Fibrillation in a patient with TRPM4 mutation","authors":"Sriram Easwaran ,&nbsp;Vedica Sethi ,&nbsp;Vijay Surampalli ,&nbsp;Yash Lokhandwala","doi":"10.1016/j.ipej.2025.03.003","DOIUrl":"10.1016/j.ipej.2025.03.003","url":null,"abstract":"<div><div>Inherited channelopathies are a cause of syncope in a structurally normal heart with subtle signs on baseline ECG, but sometimes these signs may be absent. The precipitant may either be a tachy or a bradyarrhythmia needing prompt diagnosis and treatment institution. One such cause is short coupled Ventricular fibrillation (VF) where the baseline ECG has a normal corrected QT interval (QTc) with multiple Ventricular Premature Complexes (VPCs) noted in the ECG especially around an event of syncope. The TRPM4 gene, encoding the Transient Receptor Potential Melastatin 4 ion channel, currently a variant of unknown significance is a calcium activated channel which is involved in regulation of the diastolic depolarization in the Sinoatrial (SA) node. Loss of function mutation of the gene may present as bradyarrhythmias or atrial arrhythmias due to conduction disturbances. We present a case of intractable short coupled VF with a coexistent tachy-brady syndrome, attributed to TRPM4 mutation. Due to persistent intractable VF despite antiarrhythmic therapy and implantable cardioverter-defibrillator (ICD), patient was given quinine instead of quinidine due to non-availability of the same, which led to significant alleviation of symptoms. This case underscores the complexity of managing ventricular arrhythmias and highlights the potential therapeutic role of quinine in select cases, in the scenario of unavailability of quinidine, offering insights into personalized treatment approaches for these challenging conditions.</div></div>","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":"25 2","pages":"Pages 108-111"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143606661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Conduction disease in cardiac amyloidosis patients: A case series suggesting a role for left bundle branch area pacing","authors":"Ojas H. Mehta ,&nbsp;Keyrian Louis Le Gratiet ,&nbsp;Markus Sikkel ,&nbsp;Laurence D. Sterns","doi":"10.1016/j.ipej.2025.01.001","DOIUrl":"10.1016/j.ipej.2025.01.001","url":null,"abstract":"<div><div>Transthyretin Cardiac amyloidosis (ATTR-CA) is an increasingly recognised cause of heart failure in our elderly patients with preserved ejection fraction. Patients with ATTR-CA who require permanent pacemaker implantation often have preserved ejection fraction and do not meet the clinical indication for cardiac resynchronization therapy (CRT). In these patients, left bundle branch area pacing (LBBAP) can be a reasonable option to maximise physiological activation of the left ventricle. We describe a series of three patients with cardiac amyloidosis who have undergone LBBAP with the use of lumenless leads and successful capture of the myocardium and left bundle branch region.</div></div>","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":"25 2","pages":"Pages 104-107"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142928331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Real-world single-center preliminary experience of radiofrequency balloon pulmonary vein ablation for atrial fibrillation","authors":"Andrea Dell’Aquila ,&nbsp;Carmelo La Greca ,&nbsp;Amedeo Prezioso ,&nbsp;Simone Zanchi ,&nbsp;Joseph Antoine Kheir ,&nbsp;Domenico Pecora","doi":"10.1016/j.ipej.2025.01.003","DOIUrl":"10.1016/j.ipej.2025.01.003","url":null,"abstract":"<div><div>Atrial fibrillation (AF) is the most common cardiac arrhythmia and pulmonary vein isolation (PVI) by percutaneous transcatheter ablation is its pivotal treatment. Nowadays, several techniques using different energy sources are used, such as radiofrequency (RF), cryoablation and laser ablation. A new technology that combines the strengths of different techniques has been developed, in particular having both the speed of one-shot techniques and the selectivity and precision of point-by-point RF: the RF balloon (RFB). Recent clinical studies^1–3 have demonstrated its efficacy and safety, with good results in terms of first pass isolation, procedural duration and fluoroscopy time. However, real-world data regarding RFB ablation is scarce, therefore with this study we aimed to describe the experience of our center with this technology (one of the first adopting it in our country). We prospectively enrolled in a single-center a total of 20 consecutive patients who underwent AF ablation with RFB. The primary endpoint, i.e. PVI defined as stable absence of any electrical conduction from and into the veins, was met by 18 patient (90 %). Mean procedural and fluoroscopy times were 79 ± 30.68 min and and 15.36 ± 6.57 min, respectively, dwelling time was 30.3 ± 8.09 min. The only complication reported was a single case mild pericardial effusion 24 h after the procedure, likely of inflammatory nature, which was treated conservatively and resolved before discharge. With this study we demonstrated that PVI with RFB appears to be an effective and safe technique in a real world setting, with many upsides and a reduced atrial dwelling time that theoretically could reduce the risk of thromboembolic complications. Further studies on larger number of patients are needed to confirm the results we obtained.</div></div>","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":"25 2","pages":"Pages 68-73"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143047332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"EHRA 2025- A voyage into the future!","authors":"Bharatraj Banavalikar","doi":"10.1016/j.ipej.2025.04.006","DOIUrl":"10.1016/j.ipej.2025.04.006","url":null,"abstract":"","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":"25 2","pages":"Page 57"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143934836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Loss of Cardiac Resynchronization with change in Posture. What is the mechanism?","authors":"Raghav Bansal,&nbsp;Kowsalya Madhu,&nbsp;Kartikeya Bhargava","doi":"10.1016/j.ipej.2025.04.005","DOIUrl":"10.1016/j.ipej.2025.04.005","url":null,"abstract":"","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":"25 2","pages":"Pages 126-128"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143934834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lead fracture in stylet driven left bundle area pacing following exercise: Coincidence!","authors":"Jyotika Gupta ,&nbsp;Pooja Shah ,&nbsp;Anoop K. Gupta","doi":"10.1016/j.ipej.2025.02.002","DOIUrl":"10.1016/j.ipej.2025.02.002","url":null,"abstract":"<div><div>Lumen less leads (LLLs) and stylet-driven leads (SDL) are widely used for left bundle branch area pacing (LBBAP) and has become standard practice. The incidence of lead fracture is very rare with both leads. We report a case of delayed fracture in stylet driven lead producing syncope following exercise.</div></div>","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":"25 2","pages":"Pages 122-125"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143524750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transvenous lead extraction: Experience from a Northern State of India - The Srinagar extraction registry","authors":"Ajaz A. Lone ,&nbsp;Mohd Iqbal Dar ,&nbsp;Jan Mohd Sheikh ,&nbsp;Sheikh Mohamad Tahir ,&nbsp;Waseem Rashid ,&nbsp;Imran Hafeez ,&nbsp;Hilal A. Rather ,&nbsp;Syed Bilal","doi":"10.1016/j.ipej.2025.03.002","DOIUrl":"10.1016/j.ipej.2025.03.002","url":null,"abstract":"","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":"25 2","pages":"Pages 58-66"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143587557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The radiofrequency balloon catheter for pulmonary vein isolation: Current state of play","authors":"Mark T. Mills MBChB MSc ,&nbsp;Dhiraj Gupta MD","doi":"10.1016/j.ipej.2025.04.002","DOIUrl":"10.1016/j.ipej.2025.04.002","url":null,"abstract":"","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":"25 2","pages":"Pages 74-75"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143934838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expect the unexpected. Lead extraction – A perfect example?","authors":"Brigitte Osswald","doi":"10.1016/j.ipej.2025.04.003","DOIUrl":"10.1016/j.ipej.2025.04.003","url":null,"abstract":"","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":"25 2","pages":"Page 67"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143934837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Catheter ablation versus medical therapy for ventricular tachycardia in patients with ischemic heart disease: A systematic review and meta-analysis of randomized controlled trials","authors":"Ubaid Khan ,&nbsp;Yehya Khlidj ,&nbsp;Ahmed A. Ibrahim ,&nbsp;Ahmed Mazen Amin ,&nbsp;Mohamed Saad Rakab ,&nbsp;Majd M. AlBarakat ,&nbsp;Muhammad Haris Khan ,&nbsp;Zuhair Majeed ,&nbsp;Muhammad Imran ,&nbsp;Junaid Ali ,&nbsp;Chet RanaBhat ,&nbsp;Wajeeh Ur Rehman ,&nbsp;Justin Brilliant ,&nbsp;Kashif Chaudhry","doi":"10.1016/j.ipej.2025.03.004","DOIUrl":"10.1016/j.ipej.2025.03.004","url":null,"abstract":"<div><h3>Background</h3><div>Ventricular tachycardia (VT) is a common chronic complication of ischemic heart disease (IHD), even in the era of contemporary coronary intervention. The use of implantable cardioverter-defibrillators (ICDs) has reduced mortality, but ICD shocks can be painful and traumatizing. Catheter ablation has been posited to reduce VT incidence and is commonly used in IHD patients when antiarrhythmic drugs do not suppress VT.</div></div><div><h3>Purpose</h3><div>We aim to review the clinical efficacy and safety of catheter ablation vs medical therapy in patients with IHD.</div></div><div><h3>Methods</h3><div>We conducted comprehensive searches across PubMed, CENTRAL, Web of Science, Scopus, and Embase until May 2024. Pooled data were reported using risk ratio (RR) for dichotomous outcomes and mean difference (MD) for continuous outcomes. This systematic review and meta-analysis was registered with PROSPERO ID: CRD42024551760.</div></div><div><h3>Results</h3><div>We included eight RCTs with a total of 1252 patients. Patients who underwent catheter ablation had a lower risk of VT storms compared to those who received medical therapy alone [RR: 0.74 with 95 % CI: (0.60, 0.91), P = 0.005), Compared to medical therapy, the catheter ablation group also required less appropriate ICD therapy [RR: 0.72 with 95 % CI: (0.57, 0.90), P = 0.005), and fewer appropriate ICD shocks [RR: 0.75 with 95 % CI: (0.57, 0.99), P = 0.04). However, there was no significant difference in Ventricular tachycardia/Ventricular fibrillation (VT/VF) recurrence [RR: 0.94 with 95 % CI: (0.83, 1.06), P = 0.33) and all-cause mortality [RR: 0.87 with 95 % CI: (0.70, 1.09), P = 0.22).</div></div><div><h3>Conclusion</h3><div>Catheter ablation is associated with a significant reduction in ventricular storms, appropriate ICD therapy, and appropriate ICD shocks while demonstrating similar safety in managing VT in IHD patients compared to medical therapy alone.</div></div>","PeriodicalId":35900,"journal":{"name":"Indian Pacing and Electrophysiology Journal","volume":"25 2","pages":"Pages 91-103"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143587558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}