Stomatologiya最新文献

{"title":"[Melanoma of the maxillary sinus mucosa].","authors":"M Yu Beteeva, I A Zaderenko, K S Mkrtchyan, A A Muraev","doi":"10.17116/stomat202510402182","DOIUrl":"10.17116/stomat202510402182","url":null,"abstract":"<p><p>The article presents an overview of the intermediate results of treatment for maxillary sinus melanoma in a 66-year-old patient. The importance of timely diagnosis and active surgical tactics for achieving the best survival results up to 5 years is noted. After further examination, the diagnosis was confirmed, the patient underwent genomic sequencing of the tumor tissue biopsy, which revealed a BRAF mutation. In this regard, adjuvant therapy was prescribed according to the dabrafenib+trametinib regimen. It was noted that this rare pathology requires careful study, monitoring of clinical outcomes and features of surgical tactics, considering the multifocal nature of the tumor and its high aggressiveness in comparison with the cutaneous form. In the future, the possibility of surgical intervention is discussed, extensive resection is considered, the expected volume, which can reach the removal of both soft tissue and bone structures up to resection of a part of the lower wall of the orbit.</p>","PeriodicalId":35887,"journal":{"name":"Stomatologiya","volume":"104 2","pages":"82-85"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144188203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[3D-morphometric analysis of stomatognatic system in patients with class II malocclusion according to CBCT].","authors":"N Yu Oborotistov, Yu A Gioeva, Y I Afanaseva, E I Karamisheva","doi":"10.17116/stomat202510405137","DOIUrl":"https://doi.org/10.17116/stomat202510405137","url":null,"abstract":"<p><strong>Objective: </strong>To conduct a comparative analysis of the sizes and positions of maxillofacial structures in patients with distal occlusion (gnathic and dentoalveolar forms) using a new 3D analysis.</p><p><strong>Material and methods: </strong>The object of the study were 132 patients with the gnathic form of distal occlusion of both sexes aged 18 to 45 years, including 79 women and 53 men. All patients underwent cone-beam computed tomography of the skull using KavoExam equipment with subsequent automated 3D cephalometric calculation in ViSurgery 3Dstudio software. We assessed 3D parameters on the right and left sides, as well as their 2D projection onto the midsagittal plane constructed using landmarks - cephalometric points S, N, A. Linear and angular parameters of the position and relative position of the jaws were determined using the values of Witts, SNA, SNB, ANB, B-A-Pg, S-N-Pg, ML-R/NSL, ML-L/NSL, NL-R/ML-R, NL-L/ML-L, ML/OcP, GoR - PNS, GoL-PNS and their projection onto the midsagittal plane. The angular parameters determining the direction of facial skull growth on the right and left corresponded to N-S-ArR, N-S-ArL, ArR-GoR-Me, ArL-GoL-Me, CoR-GoR-Me, CoL-GoL-Me. The angles and sizes of the position of the upper (∠SNA, PNS-A'), lower (∠SNB, Go-Pg) jaw relative to the anterior base of the skull, and the intermaxillary angle (∠ANB) were determined.</p><p><strong>Results: </strong>In both males and females, the gnathic form of distal occlusion was caused by lower retro-, micrognathia with prevalence of the horizontal type of growth of the facial part of the skull. For males and females with the dentoalveolar form of distal occlusion, the vertical type of growth of the facial part of the skull was characteristic; at the same time, lower micrognathia was noted, as in individuals with the gnathic form of distal occlusion.</p><p><strong>Conclusion: </strong>The proposed cephalometric analysis in the ViSurgery software allows for an automated detailed study of the cranial-maxillary relationships in three-dimensional space and a complete picture of the severity and determinacy of the existing anomaly.</p>","PeriodicalId":35887,"journal":{"name":"Stomatologiya","volume":"104 5","pages":"37-42"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145423020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Evaluation of the effectiveness of adaptation of children with autism spectrum disorders to dental care].","authors":"E A Nagoeva, A M Kardangusheva","doi":"10.17116/stomat202510405143","DOIUrl":"https://doi.org/10.17116/stomat202510405143","url":null,"abstract":"<p><strong>Objective: </strong>The aim the studi is to evaluation of the effectiveness of the method of adaptation of children with autism spectrum disorders to a dental appointment using augmented reality technology.</p><p><strong>Materials and methods: </strong>76 children with autism spectrum disorders aged 3 to 16 years were examined and divided into 2 comparable groups. In group 1, standard adaptation of children to a dentist's appointment was carried out, in group 2, a method of adaptation of children developed using augmented reality (AR) technology was additionally used. To determine the degree of anxiety of children with autism, the Frankl behavioral scale was used before and after the application of the developed adaptation method.</p><p><strong>Results: </strong>In the second group, more children with autism spectrum disorders adapted to dental visits. Specifically, the percentage of children displaying absolutely negative behavior dropped significantly (from 26.3% to 2.6%, <i>p</i><0.05), as did those with negative behavior (from 23.7% to 2.6%, <i>p</i><0.05). Conversely, the number of children exhibiting absolutely positive behavior increased (from 26.3% to 50%, <i>p</i><0.05). Overall, the percentage of children with negative or absolutely negative behavior decreased dramatically, from 50% to 5.2% (<i>p</i><0.05). These findings demonstrate the effectiveness of the proposed methodology and support its recommendation for practical use.</p><p><strong>Conclusion: </strong>The use of the technique for adapting children with ASD to a dental appointment, developed using PAP and AR technology, helps to reduce the manifestation of undesirable behavior in children with ASD and can be used to prepare a child for a dental appointment and dental manipulations.</p>","PeriodicalId":35887,"journal":{"name":"Stomatologiya","volume":"104 5","pages":"43-47"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145423023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Molar-incisor hypomineralization and its association with dental caries among adolescents in the European North of Russia].","authors":"M A Gorbatova, E A Mitkina, T N Yushmanova, A A Simakova, A M Grjibovski","doi":"10.17116/stomat202510405148","DOIUrl":"https://doi.org/10.17116/stomat202510405148","url":null,"abstract":"<p><strong>Objective: </strong>The aim of the study to assess the prevalence of MIH among adolescents in the Nenets Autonomous Okrug (NAO), the Komi Republic (KR), and the Murmansk region (MR), as well as associations between MIH and caries experience.</p><p><strong>Material and methods: </strong>This cross-sectional study included 250, 189, and 126 adolescents aged 15-17 years, residing in NAO (Naryan-Mar and 3 rural settlements), KR (Syktyvkar), and MR (Murmansk), respectively. The Weerheijm criteria were used to diagnose MIH. Caries experience was assessed using the WHO methodology (2013) with the calculation of the DMFT index and its components. All indicators were calculated with 95% confidence intervals (CIs). Differences in categorical and numeric variables were analyzed using non-parametric Pearson's chi-squared and Mann-Whitney tests, respectively.</p><p><strong>Results: </strong>The prevalence of MIH in the studied regions was 5.20% in NAO, 3.70% in KR, and 4.76% in MR. The CPI index was significantly higher in adolescents with MRC of 7.62 than in those with normal enamel structure of 5.48 due to a greater number of carious teeth of 2.23 and 1.13, respectively. When assessing the prevalence of MIH by gender, it was determined that in the of Komi Republic, the frequency of MIH among girls was significantly higher - 6.00% versus 1.12% among boys, while statistical significance was not achieved.</p><p><strong>Conclusions: </strong>The prevalence of MIH among adolescents in the studied areas of the Russian North is significantly lower than in most other countries. However, adolescents with MIH exhibit a significantly higher intensity of carious lesions, warranting the development of preventive measures targeting MIH.</p>","PeriodicalId":35887,"journal":{"name":"Stomatologiya","volume":"104 5","pages":"48-52"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145423112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Osteoplastic materials based on three-dimensional PLGA matrices, adenoviral vectors with the BMP2 gene and platelet gel].","authors":"I A Nedorubova, V P Basina, A V Mironov, E M Dobler, T B Bukharova, A A Kulakov","doi":"10.17116/stomat202510406225","DOIUrl":"https://doi.org/10.17116/stomat202510406225","url":null,"abstract":"<p><strong>Objective: </strong>Investigate the effect of platelet gel addition on the biological properties of 3D PLGA-based matrices impregnated with adenoviral constructs carrying the <i>BMP2</i> gene.</p><p><strong>Materials and methods: </strong>The matrices were obtained using antisolvent 3D printing. The release kinetics of adenoviral vectors from matrices were studied by spectrophotometry for the presence of viral DNA. The cytocompatibility of the matrices was assessed using the MTT test and by staining cells with fluorescent dyes. To assess the osteogenic differentiation of multipotent mesenchymal stromal cells (MSCs), the expression of osteogenic marker genes analyzed using real-time PCR and the activity of alkaline phosphatase was determined spectrophotometrically.</p><p><strong>Results: </strong>The studied gene-activated matrices based on PLGA and platelet gel demonstrated high cytocompatibility when incubated with MSCs. Viral particles released from the matrices effectively transduced cells and promoted the induction of osteogenic differentiation of MSCs. The inclusion of platelet-rich plasma into the gene-activated matrices enabled prolonged release of adenoviral constructs and a significantly enhanced cell proliferation and osteogenic differentiation of MSCs.</p><p><strong>Conclusion: </strong>The use of gene-activated matrices based on PLGA, platelet gel, and adenoviral constructs with the <i>BMP2</i> gene will accelerate bone regeneration due to the synergistic action of the osteoinductor produced as a result of viral vectors transduction and the components of platelet-rich plasma.</p>","PeriodicalId":35887,"journal":{"name":"Stomatologiya","volume":"104 6. Vyp. 2","pages":"25-31"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145726557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Clinical outcomes of patients following apical surgery with retrograde root-end filling using two different materials].","authors":"L A Nadzharyan, V A Badalyan, B V Sheplev","doi":"10.17116/stomat202510406251","DOIUrl":"10.17116/stomat202510406251","url":null,"abstract":"<p><p>In certain clinical cases where orthograde treatment of chronic apical periodontitis is either impossible or ineffective, apical surgery with retrograde filling is considered the preferred method. When selecting a retrograde filling material, key factors such as biocompatibility, ability to provide a reliable seal, ease of use, and availability are taken into account. Despite numerous studies investigating the influence of various retrograde filling materials on the outcomes of apical surgery, there is still no consensus on the most effective material. Therefore, further research in this area remains an important and relevant task. The aim of this study was to evaluate the effectiveness of mineral trioxide aggregate (MTA) and glass ionomer cement as retrograde filling materials. The study included 40 patients diagnosed with chronic apical periodontitis (ICD-10 code K04.5). Patients were randomly assigned to two groups: the first group (24 patients) received retrograde filling with the new material Dia-Root BioMTA, while the second group (16 patients) was treated with glass ionomer cement Ketac Cem. Healing dynamics were assessed using the periapical index (PAI) before surgery and at 3, 6, and 12 months postoperatively. The results demonstrated a significant and sustained reduction of inflammation in both groups, with no statistically significant differences between them, indicating comparable effectiveness of the materials used.</p>","PeriodicalId":35887,"journal":{"name":"Stomatologiya","volume":"104 6. Vyp. 2","pages":"51-55"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145726542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Clinical and functional justification of immediate loading of implants based on microhemodynamics and oxygenation data in the alveolar ridge mucosa].","authors":"F F Losev, T V Brailovskaya, E K Krechina, Z M Abaev, R V Kalinin","doi":"10.17116/stomat202510406131","DOIUrl":"https://doi.org/10.17116/stomat202510406131","url":null,"abstract":"<p><strong>Objective: </strong>Evaluation of the effectiveness of one-stage dental implantation and temporary prosthetics based on microhemodynamics and oxygenation data in the mucous membrane of the alveolar ridge.</p><p><strong>Material and methods: </strong>A clinical and functional study was conducted after simultaneous dental implantation and temporary prosthetics in 80 patients. Depending on the temporary orthopedic structure used (removable/non-removable), patients are divided into 2 groups of 40 people each. The microcirculation index (M, perfect units), characterizing the level of tissue blood flow, was determined; the parameter \"σ\" (perfect units), determining the intensity of blood flow; the bypass index (PS, standard units), the index of perfusion oxygen saturation (Sm, %) and the index of specific oxygen consumption (U, %).</p><p><strong>Results: </strong>The analysis of LDF results in group I showed that 3 days after the surgery, the blood flow level (M) and its intensity (σ) increased by 85% and 106%, respectively, and 104% and 88%, which indicated the development of hyperemia in the microcirculatory bed, which was stopped after 2 months in subgroup A and 3 months in subgroup B. In the second group, the dynamics of tissue blood flow 3 days after the surgery was similar, but microcirculation indicators were restored after 4 and 6 months. According to optical tissue oximetry (OTO) in the first group, 3 days after the surgery, the oxygenation indicator increased by 11% and 13% (subgroup A) and 6% and 18% (subgroup B), which indicated the development of tissue hyperemia, which was stopped after 2 months and 3 months after the surgery, respectively. In group 2 (subgroups A and B), oxygenation indicators were restored after 4 and 6 months, respectively.</p><p><strong>Conclusions: </strong>After one-stage dental implantation and temporary prosthetics, microhemodynamics and oxygenation in the mucous membrane of the alveolar ridge were restored after 2 and 3 months, in group I, in group II the recovery periods were 4 and 6 months.</p>","PeriodicalId":35887,"journal":{"name":"Stomatologiya","volume":"104 6","pages":"31-37"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145769303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Analysis of additional methods for improving the accuracy of intraoral scanning in edentulous patients for fixed dental prosthesis].","authors":"F F Losev, L B Borovsky","doi":"10.17116/stomat202510406149","DOIUrl":"https://doi.org/10.17116/stomat202510406149","url":null,"abstract":"<p><p>The implementation of the intraoral scanner has simplified the workflow of dentists in today's dentistry greatly, offering a fast and accurate alternative to traditional impression-taking methods and significantly streamlining the logistics process between the clinic and the dental laboratory. However, when working with edentulous patients with dental implants, intraoral scanners encounter a number of technical difficulties related to their optical-based capture and post-process algorithms, which can affect the accuracy of the data obtained. Despite progress, full digital workflow still lacks the analog silicone and stone accuracy and trueness in terms of linear and axial positioning of dental implants in casts. Nevertheless, the use of additional data sources during scanning, such as modified scan markers and auxiliary optical landmarks, can improve scan quality.</p>","PeriodicalId":35887,"journal":{"name":"Stomatologiya","volume":"104 6","pages":"49-54"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145769319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Modern approach in management of patients with lower third face lacerated wounds].","authors":"V S Zaharyan, O V Tsymbalov, A A Martirosyan, S A Vartanyan, A K Nazarova","doi":"10.17116/stomat202510406116","DOIUrl":"https://doi.org/10.17116/stomat202510406116","url":null,"abstract":"<p><strong>Background: </strong>The use of a full-thickness donor flap for lip defect closure requires a fundamental reconsideration.</p><p><strong>Objective: </strong>The aim of the study was to develop and demonstrate the effectiveness of an original bioengineering construct using a combination of a free connective tissue graft, a free periauricular skin flap, and the patient's own platelet-rich plasma, rich in fibrin, for lip defect reconstruction.</p><p><strong>Materials and methods: </strong>The study included 50 patients with lacerated lip wounds with soft tissue defects. PRF in the APRF modification was obtained from the patient's venous blood. The free connective tissue graft (CTG) was obtained traditionally from the patient's palate according to defect dimensions. The free skin flap (FSF) was harvested from the posterior surface of the earlobe, the wound edges were mobilized and sutured. In order to achieve prolonged stabilization of the defect edges and prevent conformational postoperative changes, circular muscle mobilization of the mouth was performed and fixed with an intramuscular guiding suture, along with the administration of Botulinum toxin type A (Microgen Relatox). Postoperatively, the patient underwent daily dressings, monitoring, and prevention of secondary infection. Broad-spectrum antibiotics were prescribed, as well as rabies and tetanus vaccinations.</p><p><strong>Results: </strong>A bioengineering complex was developed for lip defect reconstruction, the novelty and effectiveness of which are confirmed by invention patents. There were no cases of necrosis or rejection of the transplanted material. The surgery and subsequent monitoring were conducted on an outpatient basis. Stitches were removed after 14 days from the main defect area, after 7 days from the earlobe, and after 5 days from the hard palate. Sensitivity of the reconstructed tissues appeared on average after 3-4 months. The structure and color of the red border were optimized after 4-5 months. Recovery of blood supply in the created bioconstruct in the middle area was observed after 2 weeks. Basic voluntary lip movements were possible after 1-2 months.</p>","PeriodicalId":35887,"journal":{"name":"Stomatologiya","volume":"104 6","pages":"16-21"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145769407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Short and long-term results of bone grafting of the maxillary alveolar process in patients with alveolar ridge cleft].","authors":"V A Pavlovich, L V Ageeva, M M Afanaseva, I A Potapova, K F Mirzonazarov","doi":"10.17116/stomat202510402124","DOIUrl":"https://doi.org/10.17116/stomat202510402124","url":null,"abstract":"<p><strong>The purpose of this study: </strong>Was to evaluate alveolar bone grafting success using the autograft from the mandibular body, own bone fragments and xenogeneic material.</p><p><strong>Material and methods: </strong>This study was conducted by Central Research Institute of Dentistry and Maxillofacial Surgery (Moscow, Russia) from 2013 through 2023. Consecutive 128 patients with cleft lip/palate who underwent alveolar bone grafting by one surgeon were included. The median age at alveolar bone graft was 12.7 years (range 7-23 years). Inclusion criteria were unilateral and bilateral cleft lip and alveolus and a computed tomography (CT) scan obtained >8 months (128 patients) and 2-10 years (range 3.2 years, 52 patients) after alveolar bone grafting.</p><p><strong>Results: </strong>The success rate of surgical intervention was 92.6%. Alveolar bone graft undergoes remodeling but not lysis long-term.</p><p><strong>Conclusion: </strong>Alveolar bone grafting with mandibular bone proved to be effective and has demonstrated good long-term results. The bone level in the grafted area was satisfactory with no signs of resorption.</p>","PeriodicalId":35887,"journal":{"name":"Stomatologiya","volume":"104 2","pages":"24-29"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144188205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}