{"title":"[A case of recurrent liver metastasis from a rectal neuroendocrine tumor 9 years after endoscopic resection].","authors":"Shotaro Akiba, Takumi Hanatani, Hidekazu Horiuchi, Kazuo Okumoto, Shigemi Hachinohe","doi":"10.11405/nisshoshi.123.284","DOIUrl":"https://doi.org/10.11405/nisshoshi.123.284","url":null,"abstract":"<p><p>The patient was an 82-year-old woman who underwent endoscopic submucosal dissection for a 10mm neuroendocrine tumor (NET) in her rectum at 72 years of age. For the first 7 years, she remained free of recurrence;however, at a follow-up examination 9 years after the procedure, multiple liver tumors were detected. No recurrence was noted in the rectum. A liver biopsy revealed a dense proliferation of small cells, consistent with the findings of the original NET, leading to a diagnosis of recurrence. Currently, she is receiving treatment with lutetium-labeled octreotide. Although the guidelines regarding the optimal follow-up duration after treatment for rectal NET remain unclear, long-term surveillance is considered necessary.</p>","PeriodicalId":35808,"journal":{"name":"Japanese Journal of Gastroenterology","volume":"123 4","pages":"284-290"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147677369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Green Endoscopy:global and Japanese perspectives on sustainable development goals in gastrointestinal endoscopy].","authors":"Atsushi Imagawa, Hideki Kobara, Shintaro Fujihara","doi":"10.11405/nisshoshi.123.117","DOIUrl":"https://doi.org/10.11405/nisshoshi.123.117","url":null,"abstract":"","PeriodicalId":35808,"journal":{"name":"Japanese Journal of Gastroenterology","volume":"123 2","pages":"117-125"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146167181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[A case where phenobarbital was remarkably effective against drug-induced liver injury presenting with prolonged intrahepatic cholestasis caused by Ashwagandha].","authors":"Hideatsu Hashimoto, Tsunamasa Watanabe, Tatsuya Suzuki, Yuwa Ando, Takuya Ehira, Minoru Kanazawa, Hirotaka Koizumi, Junki Koike, Keisuke Tateishi","doi":"10.11405/nisshoshi.123.133","DOIUrl":"https://doi.org/10.11405/nisshoshi.123.133","url":null,"abstract":"<p><p>This case concerns a 39-year-old male with a history of adjustment disorder, and he had been using Ashwagandha-self-prescribed and self-imported online-for stress relief and vitality enhancement for the past 3 months. He visited the emergency department with symptoms of hyperventilation, and blood tests showed total bilirubin of 2.37mg/dL, ALT of 384U/L, and ALP of 92U/L, indicating hepatocellular-type liver dysfunction, thereby raising suspicion for drug-induced liver injury (DILI). Although ursodeoxycholic acid was initiated after referring to our hospital, his condition showed minimal improvement. A liver biopsy showed no infiltration of inflammatory cells, no dilation of the bile ducts, and no bile plugs, ruling out bile outflow obstruction. However, bilirubin deposition within hepatocytes and hepatocellular degeneration were noted. With a suspected defect in the hepatocellular bile transport, phenobarbital was started, resulting in rapid improvement of jaundice. Reports of DILI caused by Ashwagandha are rare, and this case exhibited clinical findings and test results different from those previously reported.</p>","PeriodicalId":35808,"journal":{"name":"Japanese Journal of Gastroenterology","volume":"123 2","pages":"133-140"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146167242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Frontiers of portal hypertension treatment:interpreting the Baveno VII consensus statement].","authors":"Masahito Shimizu, Takao Miwa, Yohei Shirakami","doi":"10.11405/nisshoshi.123.7","DOIUrl":"https://doi.org/10.11405/nisshoshi.123.7","url":null,"abstract":"","PeriodicalId":35808,"journal":{"name":"Japanese Journal of Gastroenterology","volume":"123 1","pages":"7-12"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145960423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Imaging diagnosis of bile duct cancer up to date].","authors":"Dai Inoue, Kazuto Kozaka","doi":"10.11405/nisshoshi.123.231","DOIUrl":"https://doi.org/10.11405/nisshoshi.123.231","url":null,"abstract":"","PeriodicalId":35808,"journal":{"name":"Japanese Journal of Gastroenterology","volume":"123 4","pages":"231-238"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147677360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Gastroenterology connected by organs].","authors":"Takanori Kanai","doi":"10.11405/nisshoshi.123.1","DOIUrl":"https://doi.org/10.11405/nisshoshi.123.1","url":null,"abstract":"","PeriodicalId":35808,"journal":{"name":"Japanese Journal of Gastroenterology","volume":"123 1","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145960466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}