{"title":"[Squamous cell carcinoma of the gallbladder with direct invasion to adjacent organs:a case report].","authors":"Atsushi Toyofuku, Masaya Bando, Koichi Nakamura, Kohei Yoshida, Yoshinori Inamasu, Tatsuhiko Kurose, Masahiro Yamasaki, Shinji Yotsumoto, Ken-Ichi Sakita, Naoki Nagata","doi":"10.11405/nisshoshi.121.971","DOIUrl":"https://doi.org/10.11405/nisshoshi.121.971","url":null,"abstract":"<p><p>A 73-year-old woman was admitted with the chief complaint of abdominal pain. Computed tomography suggested malignant tumor of the gallbladder infiltrating the liver, duodenum, and transverse colon. Extended cholecystectomy with en bloc resection of the involved liver, transverse colon, and duodenum was performed to achieve curative resection. Pathologic evaluation led to the diagnosis of stage IVA squamous cell carcinoma (T4aN0M0), according to the biliary tract cancer classification established by the Japanese Society of Hepato-Biliary-Pancreatic Surgery. Hepatic hilar lymph node recurrence was identified 3 months later and heavy ion radiotherapy was performed. The patient was hospitalized after 8 months with acute cholangitis, which improved with conservative treatment;however, heart failure worsened during treatment and she died 9 months after surgery.</p>","PeriodicalId":35808,"journal":{"name":"Japanese Journal of Gastroenterology","volume":"121 12","pages":"971-980"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142814252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Treatment of hepatocellular carcinoma and risk of decompensation and liver failure].","authors":"Tatsuya Minami, Ryosuke Tateishi, Mitsuhiro Fujishiro","doi":"10.11405/nisshoshi.121.723","DOIUrl":"https://doi.org/10.11405/nisshoshi.121.723","url":null,"abstract":"","PeriodicalId":35808,"journal":{"name":"Japanese Journal of Gastroenterology","volume":"121 9","pages":"723-728"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142297253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Ulcerative colitis diagnosed with facial pyoderma gangrenosum: a case report].","authors":"Yudai Ogata, Atsuko Soeda, Isao Saura, Emi Nemoto, Yoshitaka Tange, Chiaki Enami, Daisuke Ochi, Yuichi Dai, Shintaro Akiyama, Kazuto Ikezawa","doi":"10.11405/nisshoshi.121.481","DOIUrl":"10.11405/nisshoshi.121.481","url":null,"abstract":"<p><p>Pyoderma gangrenosum (PG) is a sterile inflammatory skin condition that is frequently associated with immune-related diseases, including inflammatory bowel disease (IBD). PG causes noninfectious ulcers. Facial PG is uncommon while PG usually occurs on the trunk and lower limbs. Herein, we report a case of a male teenager with fever, pustules, ulcers, and necrosis on both cheeks. He was initially diagnosed with complicated acne with bacterial infection, but the condition progressed to subcutaneous ulcers despite treatment. Biopsy revealed inflammatory lesions in dermal and subcutaneous tissue with neutrophil infiltration, consistent with PG. Although lacking typical IBD symptoms, blood tests revealed anemia and positive fecal occult blood. Sigmoidoscopy revealed inflammation, ulcers, and pseudopolyps in the colon and rectum, thereby diagnosing ulcerative colitis (UC). After treating PG and UC with prednisolone and skin grafts, golimumab was prescribed. The patient is now in remission. Necrotic tissue buildup can complicate closure in PG cases;this emphasizes the need for effective IBD treatment to facilitate procedures such as skin grafts.</p>","PeriodicalId":35808,"journal":{"name":"Japanese Journal of Gastroenterology","volume":"121 6","pages":"481-488"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141296839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Gallbladder carcinosarcoma associated with pancreaticobiliary maljunction with biliary dilation:a case report].","authors":"Moeka Watahiki, Junichi Kaneko, Ryota Kiuchi, Daijiro Suzuki, Toshikatsu Kosugi, Daisuke Kusama, Hiroki Tamakoshi, Tomoyuki Niwa, Masaki Takinami, Atsushi Tsuji, Masafumi Nishino, Yurimi Takahashi, Osamu Jindo, Atsuko Fukazawa, Yuzo Sasada, Takanori Yamada, Takanori Sakaguchi","doi":"10.11405/nisshoshi.121.505","DOIUrl":"10.11405/nisshoshi.121.505","url":null,"abstract":"<p><p>A 68-year-old female patient was referred to our hospital with acute cholangitis. Computed tomography revealed common bile duct dilatation, gallbladder fundal tumor, and gallbladder wall thickening attached to the tumor. Cholangiography revealed pancreaticobiliary maljunction with biliary dilation. The patient was diagnosed with pancreaticobiliary maljunction with biliary dilation and gallbladder cancer and underwent liver S4b+5 and bile duct resection and reconstruction. Pathological results revealed that the gallbladder fundal tumor included sarcoma, and the gallbladder wall thickening had adenocarcinoma;thus, the patient was diagnosed with gallbladder carcinosarcoma.</p>","PeriodicalId":35808,"journal":{"name":"Japanese Journal of Gastroenterology","volume":"121 6","pages":"505-513"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141296905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Pathological features of IBD-associated neoplasia].","authors":"Takashi Yao, Soh Okano, Makoto Kodama","doi":"10.11405/nisshoshi.121.875","DOIUrl":"https://doi.org/10.11405/nisshoshi.121.875","url":null,"abstract":"","PeriodicalId":35808,"journal":{"name":"Japanese Journal of Gastroenterology","volume":"121 11","pages":"875-881"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142629624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[A case of aortic thrombus during chemotherapy for esophageal cancer].","authors":"Yuichi Tahara, Akira Hashimoto, Hirono Owa, Takahiro Ono, Naoki Kuroda, Masatoshi Aoki, Hiroyuki Fuke, Hiroyuki Kawabata, Yoshihiro Wakita, Atsuya Shimizu","doi":"10.11405/nisshoshi.121.212","DOIUrl":"10.11405/nisshoshi.121.212","url":null,"abstract":"<p><p>A 59-year-old man presented to our hospital with a chief complaint of epigastric pain. Pertinent history included a distal gastrectomy for gastric cancer and alcohol dependence. He underwent contrast-enhanced computed tomography (CT) and esophagogastroduodenoscopy, which led to a diagnosis of esophageal cancer (cT2N2M1, stage IVb). Subsequently, he underwent chemotherapy using 5-fluorouracil and cis-diamminedichloroplatinum and radiotherapy. A total of 44 days after treatment initiation, the patient experienced nausea and hepatobiliary enzyme elevation. CT and abdominal ultrasonography were performed, and he was diagnosed with an abdominal aortic thrombus. Intravenous heparin was administered as an anticoagulant therapy. Twenty-two days after treatment initiation, the thrombus was no longer visible on abdominal ultrasonography. The patient was then treated with warfarin. It cannot be ruled out that the patient's hepatobiliary enzyme elevation was induced by the anticancer drugs. However, enzyme elevation improved with the disappearance of the abdominal aortic thrombus, suggesting that the aortic thrombus may have contributed to the hepatobiliary enzyme elevation. No thrombus recurrence was observed until the patient's death after an initial treatment with antithrombotic agents. This case indicates that malignant tumors and chemotherapy can cause aortic thrombi, and thus, care should be exercised in monitoring this potential complication.</p>","PeriodicalId":35808,"journal":{"name":"Japanese Journal of Gastroenterology","volume":"121 3","pages":"212-220"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140094755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Current status and issues of colorectal cancer screening - toward the introduction of colonoscopy into the population-based screening program].","authors":"Takahisa Matsuda, Masau Sekiguchi, Nozomu Kobayashi","doi":"10.11405/nisshoshi.121.177","DOIUrl":"10.11405/nisshoshi.121.177","url":null,"abstract":"","PeriodicalId":35808,"journal":{"name":"Japanese Journal of Gastroenterology","volume":"121 3","pages":"177-185"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140094760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}