{"title":"[Aortoesophageal fistula 19 years post-chemoradiotherapy for advanced esophageal cancer:a case report].","authors":"Shinichiro Odo, Yuichi Masui, Shinya Ikeda, Taiyo Hirata, Masanori Matsuda, Asami Kawai, Shinya Endo, Takafumi Kurokami, Kazuyo Yasuda, Kazuya Ohno","doi":"10.11405/nisshoshi.123.362","DOIUrl":"10.11405/nisshoshi.123.362","url":null,"abstract":"<p><p>This case report describes an 84-year-old female who developed a fatal aortoesophageal fistula (AEF) 19 years post-chemoradiotherapy (CRT) for advanced esophageal cancer (cT4N2M1b (HEP), and cStage IVB). The patient was treated with fluorouracil, cisplatin, and 50-Gy radiation and achieved complete remission with no recurrence. She remained under long-term follow-up. Two years before the fatal event, an esophageal ulcer was noted in the irradiated area during routine endoscopy;however, the biopsy showed no malignancy. The ulcer was managed with a proton pump inhibitor, and follow-up endoscopy confirmed healing. One year later, she collapsed at home due to massive hematemesis and was transported to the emergency department in hemorrhagic shock. Emergency endoscopy revealed findings highly suggestive of AEF. Despite attempts at balloon tamponade for hemostasis, she went into cardiac arrest and could not be resuscitated. An autopsy confirmed a 3-mm fistula between the esophagus and aorta at the post-radiotherapy site. Histopathology revealed chronic radiation-induced ulceration, vascular wall thickening, and severe capillary narrowing in the outer esophageal membrane. Giemsa staining revealed bacterial infiltration at the fistula site, suggesting that secondary suppurative aortitis was the cause of fistula formation. Notably, no residual or recurrent tumor was detected. AEF is a rare but catastrophic late complication of CRT for esophageal cancer and is often fatal.</p>","PeriodicalId":35808,"journal":{"name":"Japanese Journal of Gastroenterology","volume":"123 5","pages":"362-368"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147934042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Gastroenterological work environment and ergonomics -physical burden and countermeasures from the perspective of endoscopic practice].","authors":"Yasuki Hori, Ippei Matsuzaki, Takeshi Ebara","doi":"10.11405/nisshoshi.123.89","DOIUrl":"https://doi.org/10.11405/nisshoshi.123.89","url":null,"abstract":"","PeriodicalId":35808,"journal":{"name":"Japanese Journal of Gastroenterology","volume":"123 2","pages":"89-99"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146167248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Current status and challenges of interventional radiology (IVR) in the portal hypertension disorders].","authors":"Hisashi Hidaka, Shuichirou Iwasaki, Chika Kusano","doi":"10.11405/nisshoshi.123.13","DOIUrl":"https://doi.org/10.11405/nisshoshi.123.13","url":null,"abstract":"","PeriodicalId":35808,"journal":{"name":"Japanese Journal of Gastroenterology","volume":"123 1","pages":"13-18"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145960501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Current diagnosis and treatment for biliary cancer].","authors":"Ichiro Yasuda","doi":"10.11405/nisshoshi.123.223","DOIUrl":"https://doi.org/10.11405/nisshoshi.123.223","url":null,"abstract":"","PeriodicalId":35808,"journal":{"name":"Japanese Journal of Gastroenterology","volume":"123 4","pages":"223-230"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147677362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Adult ileal duplication diagnosis using combined capsule endoscopy and computed tomography enterography with amidotrizoic acid meglumine solution: a case report].","authors":"Kaho Hamamoto, Shinichi Hashimoto, Yuko Yamaoka, Shunsuke Ito, Atsushi Goto, Koichi Hamabe, Jun Nishikawa, Hiroo Kawano, Taro Takami","doi":"10.11405/nisshoshi.123.49","DOIUrl":"10.11405/nisshoshi.123.49","url":null,"abstract":"<p><p>A 67-year-old man with complaints of dark red stools was admitted to the hospital. Capsule endoscopy, computed tomography enterography (CTE) with amidotrizoic acid meglumine solution (AM), and transanal double-balloon enteroscopy revealed a diverticulum in the ileum, which was accompanied by an ulcer in the vicinity. A partial ileal resection was performed laparoscopically, and the intraoperative and pathological findings indicated that the patient had a duplicated intestinal tract. Intriguingly, we identified a few reports on preoperative diagnosis of ileal duplication;however, we experienced such a case wherein the combination of capsule endoscopy and CTE using AM aided in its diagnosis.</p>","PeriodicalId":35808,"journal":{"name":"Japanese Journal of Gastroenterology","volume":"123 1","pages":"49-56"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145960403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Pneumatosis cystoides intestinalis with extensive intraperitoneal free air, retroperitoneal emphysema, and pneumomediastinum:a case report].","authors":"Aidehamu Aihemaiti, Fumihiko Nakamura, Kentaro Ishii, Yoshihiro Ota, Yukako Nemoto","doi":"10.11405/nisshoshi.123.191","DOIUrl":"10.11405/nisshoshi.123.191","url":null,"abstract":"<p><p>Pneumatosis cystoides intestinalis is characterized by the presence of several gas-filled cysts within the intestinal wall. Here, we report an exceptionally rare case, wherein pneumatosis cystoides intestinalis extended from the ileum through the right colon to the splenic flexure, accompanied by intraperitoneal free air, retroperitoneal emphysema, and mediastinal emphysema. The patient reported a complex medical history, including interstitial lung disease and bronchial asthma, and received steroid treatment alongside α-glucosidase inhibitors for diabetes mellitus. Conservative management was selected because of the absence of significant subjective symptoms and minimal abnormalities on abdominal examination despite striking radiological findings. The patient's condition improved rapidly after hospitalization.</p>","PeriodicalId":35808,"journal":{"name":"Japanese Journal of Gastroenterology","volume":"123 3","pages":"191-198"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147436518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Sustainable gastrointestinal surgery pioneered by gender studies].","authors":"Emiko Kono","doi":"10.11405/nisshoshi.123.111","DOIUrl":"https://doi.org/10.11405/nisshoshi.123.111","url":null,"abstract":"","PeriodicalId":35808,"journal":{"name":"Japanese Journal of Gastroenterology","volume":"123 2","pages":"111-116"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146167200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Advanced colorectal cancer in a 19-year-old male patient with Lynch syndrome:a case report].","authors":"Kanami Ota, Akira Harada, Yu Kajiya, Shiro Iwatake, Hiroshi Suekane, Junji Umeno","doi":"10.11405/nisshoshi.123.199","DOIUrl":"10.11405/nisshoshi.123.199","url":null,"abstract":"<p><p>A 19-year-old male patient with abdominal pain and diarrhea was presented to our hospital. He was diagnosed with advanced colorectal cancer based on imaging. Lynch syndrome was suspected, considering his family history. After a laparoscopic subtotal colectomy, genetic testing confirmed a pathogenic variant in the MLH1 gene, leading to a definitive diagnosis of Lynch syndrome. The onset of colorectal cancer is extremely rare in the teenage years. Herein, we discuss the potential involvement of genetic anticipation, emphasize the importance of early surveillance in individuals at risk, and consider the use of multidisciplinary collaboration in providing comprehensive physical and psychological support.</p>","PeriodicalId":35808,"journal":{"name":"Japanese Journal of Gastroenterology","volume":"123 3","pages":"199-206"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147436360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}