{"title":"[Image-enhanced endoscopy and AI in upper gastrointestinal screening].","authors":"Toshiaki Hirasawa, Sho Suzuki, Tomohiro Tada","doi":"10.11405/nisshoshi.122.112","DOIUrl":"https://doi.org/10.11405/nisshoshi.122.112","url":null,"abstract":"","PeriodicalId":35808,"journal":{"name":"Japanese Journal of Gastroenterology","volume":"122 2","pages":"112-120"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143383503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Efforts to reduce parenteral support in short bowel syndrome].","authors":"Toshiyuki Sato, Yuki Horio, Shinichiro Shinzaki","doi":"10.11405/nisshoshi.122.178","DOIUrl":"https://doi.org/10.11405/nisshoshi.122.178","url":null,"abstract":"","PeriodicalId":35808,"journal":{"name":"Japanese Journal of Gastroenterology","volume":"122 3","pages":"178-188"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143587549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Efficacy and safety of ferric carboxymaltose in patients with inflammatory bowel disease].","authors":"Yusuke Ozeki, Jun Kato, Yuki Ohta, Takashi Taida, Ryosuke Horio, Michiko Sonoda, Tatsuya Kaneko, Kenichiro Okimoto, Keiko Saito, Tomoaki Matsumura, Naoya Kato","doi":"10.11405/nisshoshi.122.196","DOIUrl":"10.11405/nisshoshi.122.196","url":null,"abstract":"<p><p>Iron deficiency anemia (IDA) is a prevalent complication in patients with inflammatory bowel disease (IBD). Ferric carboxymaltose (FCM) is a new intravenous iron formation that has been available for IDA in Japan since 2020. The present study aimed to investigate the efficacy and safety of FCM in patients with IBD and IDA. This single-center retrospective study included 41 patients with IBD treated with FCM at our hospital from September 2020 to June 2023. The FCM administered dose was 500mg in 28 patients, 1000mg in 7 patients, and >1500mg in 6 patients. The median hemoglobin level improved from 9.8g/dL to 11.8g/dL at 16 weeks after the first FCM administration during the study period. Median change in hemoglobin levels 16 weeks after the first FCM dose did not significantly differ between patients with low C-reactive protein (CRP) levels (CRP ≤0.5mg/dL;n=31) and those with high CRP levels (CRP >0.5mg/dL;n=10) (2.2g/dL vs. 1.7g/dL, p=0.94). Adverse events were observed in 6 patients, including hypophosphatemia in 2 (4.9%) and osteomalacia in 1 (2.4%). FCM administration in patients with IBD is expected to improve anemia even with fewer administrations.</p>","PeriodicalId":35808,"journal":{"name":"Japanese Journal of Gastroenterology","volume":"122 3","pages":"196-205"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143587548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Hemosuccus pancreaticus caused by pancreatic cancer treated with radiation therapy for hemostasis].","authors":"Hirofumi Harima, Harumi Suehiro, Michitaka Kawano, Tadasuke Hanazono, Kenji Mori, Yasuyo Chochi, Taro Takami","doi":"10.11405/nisshoshi.122.130","DOIUrl":"10.11405/nisshoshi.122.130","url":null,"abstract":"<p><p>A 67-year-old female patient, with a chief complaint of melena, was referred to our hospital because of a pancreatic tumor. A blood assessment revealed anemia with a hemoglobin (Hb) level of 7.7g/dL. Contrast-enhanced computed tomography (CT) detected a large pancreatic tail tumor and liver metastasis. Upper endoscopy demonstrated bile juice containing a blood-like red in the duodenum. We confirmed the pancreatic cancer diagnosis via endoscopic ultrasound-guided fine needle aspiration (EUS-FNA). CT after the procedure indicated a hematoma in the pancreatic tumor. The patient required frequent blood transfusions due to severe anemia. The second upper endoscopy demonstrated bleeding from the papilla of Vater. We diagnosed the patient with hemosuccus pancreaticus (HP). Pancreatic cancer, not hematoma, was considered to cause HP because we detected blood, such as red bile juice, before EUS-FNA. Her Hb levels decreased although she underwent coil embolization of the left gastric artery and splenic artery branches. We considered surgical treatment to stop the bleeding, but we abandoned surgery because of the pancreatic cancer invasion of the surrounding organs. We then attempted radiation therapy. Her Hb level stopped decreasing following treatment. She did not need frequent blood transfusions until she received radiation therapy and died 3 months later. The autopsy revealed a final diagnosis of anaplastic carcinoma. HP is an uncommon disease caused by bleeding from the papilla of Vater. HP is frequently caused by chronic pancreatitis, but it is also induced by a pancreatic tumor. Most HP cases received interventional radiology and surgical treatment. Here, we describe a case of HP caused by pancreatic cancer in which radiation therapy was effective for hemostasis.</p>","PeriodicalId":35808,"journal":{"name":"Japanese Journal of Gastroenterology","volume":"122 2","pages":"130-137"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143383500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Pathogenesis and treatment of primary sclerosing cholangitis -Role of the gut microbiota].","authors":"Haruka Okada, Takanori Kanai, Nobuhiro Nakamoto","doi":"10.11405/nisshoshi.122.235","DOIUrl":"https://doi.org/10.11405/nisshoshi.122.235","url":null,"abstract":"","PeriodicalId":35808,"journal":{"name":"Japanese Journal of Gastroenterology","volume":"122 4","pages":"235-247"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144044154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Drug-induced liver injury due to asymptomatically discovered Saire-to: a case report].","authors":"Soshi Oyama, Kazuo Okumoto, Shotaro Akiba, Hidekazu Horiuchi, Shigemi Hachinohe","doi":"10.11405/nisshoshi.122.216","DOIUrl":"10.11405/nisshoshi.122.216","url":null,"abstract":"<p><p>A 59-year-old female patient was prescribed Saire-to for dizziness. She demonstrated no symptoms, but a blood test conducted after 5 months revealed liver dysfunction, and thus she was referred to and admitted to our hospital. Her condition rapidly improved after drug discontinuation, and a liver biopsy test confirmed drug-induced liver injury, with a positive drug-induced lymphocyte stimulation test. Herbal medicine-induced liver damage has been increasing in recent years, many of which contain Ougon. Herbal medicines that contain Ougon pose a risk of liver damage;thus, regular blood tests are required even in the absence of symptoms.</p>","PeriodicalId":35808,"journal":{"name":"Japanese Journal of Gastroenterology","volume":"122 3","pages":"216-220"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143587546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Liver transplantation for primary sclerosing cholangitis:current status and challenges].","authors":"Shintaro Yagi, Hironori Haga, Hiroyuki Isayama","doi":"10.11405/nisshoshi.122.269","DOIUrl":"https://doi.org/10.11405/nisshoshi.122.269","url":null,"abstract":"","PeriodicalId":35808,"journal":{"name":"Japanese Journal of Gastroenterology","volume":"122 4","pages":"269-277"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144022546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}