Sudebno-Meditsinskaya Ekspertisa最新文献

[Review of «Mathematical modeling of ethanol kinetics» monograph by G.V. Nedugov]. [回顾«乙醇动力学的数学建模»由G.V. Nedugov专著]。

Sudebno-Meditsinskaya Ekspertisa Pub Date : 2025-01-01 DOI: 10.17116/sudmed20256802161

A P Ardashkin

引用次数: 0

[Towards understanding the fauna of buried corpses]. [了解埋葬尸体的动物群]。

Sudebno-Meditsinskaya Ekspertisa Pub Date : 2025-01-01 DOI: 10.17116/sudmed20256801130

V L Popov, S N Lyabzina, R V Isaev

引用次数: 0

[Adducted specific impulse as a new prognostic criterion of after-penetration local contusion trauma severity]. [内收比冲作为穿透后局部挫伤严重程度的新预后标准]。

Sudebno-Meditsinskaya Ekspertisa Pub Date : 2025-01-01 DOI: 10.17116/sudmed20256802114

A V Denisov, S M Logatkin, A P Bozhchenko, K P Golovko, I E Zhukov, I A Tolmachev

{"title":"[Adducted specific impulse as a new prognostic criterion of after-penetration local contusion trauma severity].","authors":"A V Denisov, S M Logatkin, A P Bozhchenko, K P Golovko, I E Zhukov, I A Tolmachev","doi":"10.17116/sudmed20256802114","DOIUrl":"https://doi.org/10.17116/sudmed20256802114","url":null,"abstract":"Prerequisite for a valid forensic medical assessment of gunshot wound is knowledge of the mechanisms of its formation under different conditions, in particular - under condition of the bullet's impact through the obstacle.Objective: To find the most accurate prognostic criterion of wound severity arising from high-energy local exposure to the tissues and organs of the human's chest and abdomen through such a special obstacle as body armour.Material and methods: Shooting of protective body compositions and experimental animals with ammunition and spherical firing mechanisms with varying impact load, video recording of the occurring high-speed processes, computational diagnosis were carried out.Results: The characteristics of the forming local rear deformation section without penetration of protective composition of ceramic armour panel have been established. It has been shown that this formation has a round shape, high speed of movement, limited height and large impact impulse. Simulation of impact action with spherical firing mechanisms with different mass showed the possibility of formation of similar damage at different values of kinetic, specific energy and impulse of local impact, as well as damage at similar energy and impulse values in experimental animals. The dependence of the after-penetration local contusion trauma severity is most accurately described by means of such a new criterion as the given specific impulse.Conclusion: It is advisable to use the new «specific impulse» criterion as the main prognostic criterion of after-penetration local contusion trauma severity.","PeriodicalId":35704,"journal":{"name":"Sudebno-Meditsinskaya Ekspertisa","volume":"68 2","pages":"14-20"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144062711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Determination of formation age of acute traumatic intracranial subdural hematomas using computed tomography]. 急性外伤性颅内硬膜下血肿形成年龄的计算机断层扫描研究。

Sudebno-Meditsinskaya Ekspertisa Pub Date : 2025-01-01 DOI: 10.17116/sudmed20256801117

E V Egorova, E M Kildyushov, D V Burenchev, U N Tumanova

引用次数: 0

[Evaluation of VEGF-A, SP-D and MUC-1 expression in poisoning with baclofen and its combination with ethanol]. [巴氯芬中毒及与乙醇联用后VEGF-A、SP-D和MUC-1表达的评价]。

Sudebno-Meditsinskaya Ekspertisa Pub Date : 2025-01-01 DOI: 10.17116/sudmed20256802145

O L Romanova, M L Blagonravov, P G Dzhuvalyakov, V I Torshin, E Kh Barinov, E A Lukyanova, M A Kislov

引用次数: 0

[Fatal non-thrombotic pulmonary embolism in penis enlargement with injections of hyaluronic acid-based drugs]. 【注射透明质酸类药物引起阴茎增大致死性非血栓性肺栓塞】。

Sudebno-Meditsinskaya Ekspertisa Pub Date : 2025-01-01 DOI: 10.17116/sudmed20256801159

S V Shigeev, Yu E Morozov, D V Gornostaev, O A Uspekhova

{"title":"[Fatal non-thrombotic pulmonary embolism in penis enlargement with injections of hyaluronic acid-based drugs].","authors":"S V Shigeev, Yu E Morozov, D V Gornostaev, O A Uspekhova","doi":"10.17116/sudmed20256801159","DOIUrl":"10.17116/sudmed20256801159","url":null,"abstract":"Hyaluronic acid is widely used as an injectable dermal filler in medicine, especially in plastic surgery and cosmetology, due to its biocompatibility and non-immunogenicity. However, these manipulations can cause complications, the most threatening of which is non-thrombotic pulmonary embolism. The article presents a not previously described case of this complication development in a 56-year-old man who underwent penis enlargement with unknown hyaluronic acid-based drug. He complained of general health problems, shortness of breath, sweating, weakness, nausea, tremor in the limbs, and had to seek medical attention on the day of intervention. The patient died next morning. A post-injection damage on the glans penis has been revealed in forensic autopsy, a large accumulation of foreign substance with jelly-like consistency has been found in the area of the root of penis, that was confirmed by histological study. The gel has been also found in the lumina of numerous vessels of the lung of different diameter. Spectrographic analysis established the uniformity of foreign substance from the soft tissues of the root of penis and lung vessels, and also allowed to identify it as hyaluronic acid or hyaluronic acid sodium salt. The objective of this article is to inform a wide forensic audience about the possibility of developing fatal non-thrombotic pulmonary embolism associated with hyaluronic acid injections.","PeriodicalId":35704,"journal":{"name":"Sudebno-Meditsinskaya Ekspertisa","volume":"68 1","pages":"59-62"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143524749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Sudden infant death syndrome: diagnostic problems, study algorithm]. [婴儿猝死综合征：诊断问题，研究算法]

Sudebno-Meditsinskaya Ekspertisa Pub Date : 2025-01-01 DOI: 10.17116/sudmed2025680215

S N Moskovsky, E K Emelyanova, D V Listkova

{"title":"[Sudden infant death syndrome: diagnostic problems, study algorithm].","authors":"S N Moskovsky, E K Emelyanova, D V Listkova","doi":"10.17116/sudmed2025680215","DOIUrl":"https://doi.org/10.17116/sudmed2025680215","url":null,"abstract":"«Sudden infant death syndrome» (SIDS) term unifies cases of non-violent, unexpectedly occurred death of a child under one year of age in the absence of objective data explaining the causes of death, history of disease and postmortem examination.Objective: To identify the diagnostic criteria allowing to determine the immediate cause of death in SIDS.Material and methods: We analyzed data on 64 cases of sudden deaths of infants under 1 year of age between 2016 and 2023. All cases of sudden death) were subjected to forensic medical examination arbitrarily for the purpose of excluding violent cause of death (trauma, poisoning). Judicial committee workers requested and preliminarily studied in detail the medical records. Standards of forensic medical examination, established by regulatory order (federal laws and orders) were applied in the corpse's examination. Exclusion group included cases with confirmed chronic or congenital diseases, as well as cases of violent deaths.Results: The use of an established postmortem examination algorithm and an international standardized autopsy protocol significantly increases the number of identified causes of death, while reducing the frequency of SIDS diagnoses, that in turn allows to improve the quality of health care system work worldwide.Conclusion: It is necessary to develop and implement analogue of used abroad algorithm in the practice of domestic forensic medical experts and pathologists, that will allow to reveal the most frequent causes of death of children, draw attention of medical staff to them and, as a consequence, improve the quality of life-time diagnosis and contribute to the reduction of infant mortality.","PeriodicalId":35704,"journal":{"name":"Sudebno-Meditsinskaya Ekspertisa","volume":"68 2","pages":"5-8"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144019157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Determination of tissular and species membership of hyaline cartilage microparticles by forensic cytology and enzyme-linked immunosorbent assay methods]. [用法医细胞学和酶联免疫吸附测定法测定透明软骨微粒的组织和种类]。

Sudebno-Meditsinskaya Ekspertisa Pub Date : 2025-01-01 DOI: 10.17116/sudmed20256802121

A A Gusarov, V L Sidorov, N E Surikova, O D Yagmurov

引用次数: 0

[Method of linear calibration function control according to GOST R ISO 11095-2007 for measuring the mass concentration of ethanol]. [根据 GOST R ISO 11095-2007 测量乙醇质量浓度的线性校准函数控制方法]。

Sudebno-Meditsinskaya Ekspertisa Pub Date : 2025-01-01 DOI: 10.17116/sudmed20256801143

M S Zatyamina, L A Smirnova, O V Ostrovskij, D V Kuznetsov

{"title":"[Method of linear calibration function control according to GOST R ISO 11095-2007 for measuring the mass concentration of ethanol].","authors":"M S Zatyamina, L A Smirnova, O V Ostrovskij, D V Kuznetsov","doi":"10.17116/sudmed20256801143","DOIUrl":"10.17116/sudmed20256801143","url":null,"abstract":"Objective: Implementation of the control method to validate previously obtained calibration functions according to GOST R ISO 11095-2007 using Reference Materials (RM): standard RMs - aqueous solutions of ethanol, produced and certified by the organization, and internal RMs - aqueous solutions of ethanol in different concentrations, developed by the user for internal use.Material and methods: We applied the control method in accordance with the National Standard of the Russian Federation GOST R ISO 11095-2007 using the standard and internal RMs - aqueous ethanol solutions in different concentrations. Measurements were performed for two subranges of ethanol concentrations on standard and internal RMs in accordance with the certified method.Results and conclusion: Control charts based on experimental data confirmed that the system was in a controlled state, and the calibration function required no updates on Day 7. No studied values fell outside the upper and lower control limits on the control charts. The uncertainty of the transformed values was assessed during the calibration function validation.","PeriodicalId":35704,"journal":{"name":"Sudebno-Meditsinskaya Ekspertisa","volume":"68 1","pages":"43-49"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143524683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Features of chemical and toxicological study of 1,4-dihydropyridine derivatives]. [1,4-二氢吡啶衍生物的化学特征和毒理学研究]。

Sudebno-Meditsinskaya Ekspertisa Pub Date : 2025-01-01 DOI: 10.17116/sudmed20256802137

L L Kvachakhiya, V K Shormanov, V V Karnaukhova

{"title":"[Features of chemical and toxicological study of 1,4-dihydropyridine derivatives].","authors":"L L Kvachakhiya, V K Shormanov, V V Karnaukhova","doi":"10.17116/sudmed20256802137","DOIUrl":"https://doi.org/10.17116/sudmed20256802137","url":null,"abstract":"Objective: To investigate the features of 1.4-dihydropyridine derivatives' determination in biological material in chemical and toxicological studies.Material and methods: Liquid-liquid extraction, semi-preparative column chromatography, thin-layer chromatography (TLC) and gas chromatography with mass spectrometric detection (GC-MS) were used as analysis methods.Results: It has been established that extraction of 1.4-dihydropyridine derivatives from biomaterial is most appropriate to be carried out by consecutive (by 30 min) infusion with two portions of acetone-acetonitrile (7.5:2.5) mixture at a mass ratio of the extracting liquid and bioactive matrix equal 2:1. The optimum regimen of 1.4-dihydropyridine derivatives chromatography in C-18 «Silasorb» sorbent column using acetonitrile-aqua (7:3) eluant was determined, that was realized in combined purification including the extraction with ethyl acetate from aqua-acetonitrile medium and column chromatography of analytes. Butanol-acetone (5:5) eluant may be used to identify analytes by TLC method («Sorbfil» plates). Additionally, the identification of 1.4-dihydropyridine derivatives can be performed using GC-MS (HP-5 ms Ultra inert (30 000×0.25 mm) column, immobilized phase is 5% phenyl-95% dimethylpolysiloxane, mobile phase is helium by characteristic retention time and ion sets in the analytes' mass-spectra. The same method was used for quantitative determination of studied compounds. Methods for the determination of amlodipine, nifedipine, nimodipine and felodipine were developed by GC-MS method in biomatrix model (liver tissue), that showed suitability to validation requirements by a number of key criteria. The maximum detectable and quantitatively determinable content levels of studied substances in biomatrix did not exceed 0.04-0.14 and 0.08-0.24 mg/g, respectively.","PeriodicalId":35704,"journal":{"name":"Sudebno-Meditsinskaya Ekspertisa","volume":"68 2","pages":"37-44"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144054101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0