Japanese Journal of Cancer and Chemotherapy最新文献_第7页

[Pancreaticoduodenectomy with Pancreaticogastric Anastomosis for Jehovah's Witness Patients].

Japanese Journal of Cancer and Chemotherapy Pub Date : 2025-04-01

Kenjiro Kitasato, Taku Akahoshi, Ippei Murata, Masanori Ikota, Rama Adikrisna, Tomoyuki Ohta, Sho Mineta, Yoshihiko Tsuruta

{"title":"[Pancreaticoduodenectomy with Pancreaticogastric Anastomosis for Jehovah's Witness Patients].","authors":"Kenjiro Kitasato, Taku Akahoshi, Ippei Murata, Masanori Ikota, Rama Adikrisna, Tomoyuki Ohta, Sho Mineta, Yoshihiko Tsuruta","doi":"","DOIUrl":"","url":null,"abstract":"Background: Jehovah's Witnesses followers may have limited treatment options because they do not accept blood transfusion therapy for religious reasons. In addition, pancreatoduodenectomy is known to carry a high risk of intra-abdominal bleeding due to postoperative pancreatic fistula. Our hospital has a policy of providing surgical treatment to Jehovah's Witnesses whenever possible, and we perform pancreaticoduodenectomy with pancreaticogastric anastomosis in the belief that it is less likely to cause fatal complications in the short term.Subject: Four pancreaticoduodenectomies were performed on Jehovah's Witness believers between November 2017 and May 2024. The diseases were IPMC, ampullary carcinoma, cholangiocarcinoma, and duodenal carcinoma in one case each. All patients underwent reconstruction with gastro-pancreatic anastomosis.Results: All patients completed the treatment without blood transfusion. Operation time: 514 minutes, blood loss: 290 mL. Postoperative hospital stay was 40 days. Intra-abdominal abscess was observed in one patient, but there were no hemorrhagic complications and no in-hospital death.Conclusion: Pancreaticoduodenectomy with pancreaticogastric anastomosis for Jehovah's Witnesses patient at our hospital was considered acceptable.","PeriodicalId":35588,"journal":{"name":"Japanese Journal of Cancer and Chemotherapy","volume":"52 4","pages":"351-353"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144004372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[A Case of Gastric Cancer with Mediastinal Lymph Node Recurrence Four Years after Surgery Despite Pathologically Complete Response to Preoperative Chemotherapy]. [1例胃癌纵隔淋巴结术后4年复发，术前化疗病理完全缓解]。

Japanese Journal of Cancer and Chemotherapy Pub Date : 2025-04-01

Shigeyoshi Higashi, Haruna Furukawa, Tomohiro Takahashi, Shogo Yanagi, Yoko Oga, Nobuo Takiguchi, Yoshitoshi Ichikawa, Ryo Tsunashima, Yoshiaki Omura, Masakazu Miyake, Masaki Kashiwazaki, Masahiro Tanemura

{"title":"[A Case of Gastric Cancer with Mediastinal Lymph Node Recurrence Four Years after Surgery Despite Pathologically Complete Response to Preoperative Chemotherapy].","authors":"Shigeyoshi Higashi, Haruna Furukawa, Tomohiro Takahashi, Shogo Yanagi, Yoko Oga, Nobuo Takiguchi, Yoshitoshi Ichikawa, Ryo Tsunashima, Yoshiaki Omura, Masakazu Miyake, Masaki Kashiwazaki, Masahiro Tanemura","doi":"","DOIUrl":"","url":null,"abstract":"A 71-year-old man was diagnosed with advanced gastric cancer of the upper body of the stomach by esophagogastroduodenoscopy. CT scan showed enlarged left supraclavicular fossa and mediastinal lymph nodes. U, type 4, cT4aN2M1 (LYM), Stage ⅣB was diagnosed and chemotherapy(SOX)was administered. After chemotherapy, the distant lymph nodes shrank and PET-CT scan showed no distant lymph node involvement. ycT1bN0M0, Stage Ⅰ was diagnosed. Laparoscopic total gastrectomy D2 dissection was performed as conversion surgery. Pathological findings were ypT0N0(0/34)M0 and histological response Grade 3. As postoperative adjuvant chemotherapy, S-1 was administered for about 1 year. The left supraclavicular fossa and mediastinal lymph nodes remained reduced and patients were followed up while imaging studies were performed. Four years post-operatively, the patient was diagnosed with recurrence due to elevated tumor markers and rapid enlargement of supraclavicular fossa and mediastinal lymph nodes. We experienced a case in which the patient had a pathological complete response but recurred 4 years after surgery.","PeriodicalId":35588,"journal":{"name":"Japanese Journal of Cancer and Chemotherapy","volume":"52 4","pages":"320-322"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143988139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Benefits of Laparoscopic Gastrectomy for Elderly Patients: Masato Mitsuda]. 腹腔镜胃切除术对老年患者的益处：Masato Mitsuda。

Japanese Journal of Cancer and Chemotherapy Pub Date : 2025-04-01

Daiki Matsubara, Daiki Matsubara, Mizuki Tamai, Fumiaki Ochi, Tomoya Hatakeyama, Tatsuya Kumano, Yoshiki Itokawa

{"title":"[Benefits of Laparoscopic Gastrectomy for Elderly Patients: Masato Mitsuda].","authors":"Daiki Matsubara, Daiki Matsubara, Mizuki Tamai, Fumiaki Ochi, Tomoya Hatakeyama, Tatsuya Kumano, Yoshiki Itokawa","doi":"","DOIUrl":"","url":null,"abstract":"Objective: To evaluate the outcomes of laparoscopic gastrectomy for gastric cancer in elderly patients.Methods: We evaluated the short-term outcomes of open and laparoscopic gastrectomy procedures performed in 89 patients with gastric cancer(≥80 years: n=13, <80 years: n=76)between September 2013 and March 2023.Results: There were no significant differences in patient background, surgical technique, surgical approach, pathology, or short-term outcomes. Preoperative nutritional status(PNI and GNRI)was significantly lower in the elderly group. Laparoscopic surgery was associated with a longer operative time, lower blood loss, and shorter postoperative hospital stay than open surgery. There was no difference in the rates of CD Grade 3+ complications between open and laparoscopic surgery in patients aged <80 years, while laparoscopic surgery was associated with significantly lower complication rates in patients aged ≥80 years. Considering that patients in the open surgery group were more likely to have advanced cancer, we performed a risk factor analysis for CD Grade 3+ complications in patients >80 years of age, and demonstrated that the surgical approach and operative time were significantly associated with the risk of complications.Conclusion: The results suggest that laparoscopic surgery may reduce complication rates in elderly patients.","PeriodicalId":35588,"journal":{"name":"Japanese Journal of Cancer and Chemotherapy","volume":"52 4","pages":"369-371"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144022143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[A Case of Pancreaticoduodenectomy for a Patient with Ampullary Cancer Combined with Intracystic Papillary Neoplasm]. 【壶腹癌合并囊内乳头状瘤行胰十二指肠切除术1例】。

Japanese Journal of Cancer and Chemotherapy Pub Date : 2025-04-01

Koji Hayashi, Yoshiteru Katsura, Narumi Sawamura, Risa Kawamoto, Yo Akazawa, Ryuta Ueda, Masahiro Koh, Akio Hara, Hiroshi Takeyama, Natsumi Tanaka, Naomi Urano, Shu Okamura, Chikara Ebisui, Hideoki Yokouchi, Masahiko Yano

引用次数: 0

[A Case of Advanced Gastric Cancer with Cervical Lymph Node Metastasis Responding to SOX+Nivolumab and Treated with Conversion Surgery]. [1例晚期胃癌伴颈部淋巴结转移对SOX+尼武单抗有效并行转换手术治疗]。

Japanese Journal of Cancer and Chemotherapy Pub Date : 2025-04-01

Kohki Ishimaru, Yusuke Akamaru, Kentaro Nishida, Hiromichi Miyagaki, Soichiro Mori, Masatoshi Nomura, Yukihiro Yoshikawa, Koki Tamai, Daisuke Takiuchi, Takuya Hamakawa, Mitsuyoshi Tei, Masanori Tsujie

引用次数: 0

[A Case of Anal Canal Squamous Cell Carcinoma with Extensive Rectal Stricture after Chemoradiotherapy]. 放化疗后肛管鳞状细胞癌伴广泛直肠狭窄1例。

Japanese Journal of Cancer and Chemotherapy Pub Date : 2025-04-01

Akinobu Kondo, Shota Suzuki, Satoshi Tomeoku, Tomomi Tanigawa, Ken Ichikawa, Yoshihiro Okuda, Michio Kohno, Minoru Tanaka

引用次数: 0

[A Case of Complete Cured by Multidisciplinary Treatment for Repeated Recurrent of Primary Peritoneal Cancer]. 多学科综合治疗原发性腹膜癌反复复发1例。

Japanese Journal of Cancer and Chemotherapy Pub Date : 2025-04-01

Yoshimi Hirohashi, Kazuya Uchikawa, Chieko Hotta, Hirofumi Sato, Hiroshi Kubo, Masako Asai, Yusuke Kawashima, Tomonori Shimonishi, Yoshito Akagi

{"title":"[A Case of Complete Cured by Multidisciplinary Treatment for Repeated Recurrent of Primary Peritoneal Cancer].","authors":"Yoshimi Hirohashi, Kazuya Uchikawa, Chieko Hotta, Hirofumi Sato, Hiroshi Kubo, Masako Asai, Yusuke Kawashima, Tomonori Shimonishi, Yoshito Akagi","doi":"","DOIUrl":"","url":null,"abstract":"A 56-year-old female received the low anterior resection for RS rectal cancer(T4aN1M0)in June 2010. In February 2011, abdominal CT showed paraaortic lymph node swelling, we resected it, because of lymphatic metastasis from rectal cancer suspected. The resected specimen showed the histological feature similar with ovarian cancer rather than rectal cancer. But uterus and adnexa were not unremarkable on gynecologic examination. She received FOLFOX therapy. In December 2012, abdominal CT revealed a growing mass lesion at posterior to the rectosigmoidal anastomosis. We suspected local recurrence of rectal cancer, chemoradiotherapy(S-1+39 Gy)was administrated, a recurrent lesion was reduced and was followed up. In September 2014, abdominal CT showed the local recurrent lesion enlarged, then we started FOLFIRI+cetuximab. However, tumor progressed with no effect of chemotherapy. In May 2015, we performed the low anterior resection with excision of the local recurrent lesion. Histopathological evaluation of the resected specimen revealed a serous adenocarcinoma, like an origin of ovarium on immunohistochemical examination, highly suspected primary peritoneal cancer. Systemic chemotherapy with 4 courses of carboplatin and docetaxel(DC)therapy was administrated as adjuvant chemotherapy. In December 2016, CA125 level increased, PET-CT showed FDG accumulation in the local recurrent lesion, so we started DC therapy again. The recurrent lesion was disappeared rapidly, followed by 9 courses. She is still alive without recurrence 7 years after DC therapy.","PeriodicalId":35588,"journal":{"name":"Japanese Journal of Cancer and Chemotherapy","volume":"52 4","pages":"345-347"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143999775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[A Case of Laparoscopic Total Gastrectomy and Enterostomy with R Anastomosis for Advanced Gastric Cancer in an Older Patient]. [腹腔镜全胃切除术+ R吻合术治疗老年晚期胃癌1例]。

Japanese Journal of Cancer and Chemotherapy Pub Date : 2025-04-01

Shinsuke Katsuyama, Toru Masuzawa, Keijiro Sugimura, Kiminori Yanagisawa, Go Shinke, Mitsuru Kinoshita, Ryo Ikeshima, Masayuki Hiraki, Yoshiaki Ohmura, Taishi Hata, Yutaka Takeda, Kohei Murata

{"title":"[A Case of Laparoscopic Total Gastrectomy and Enterostomy with R Anastomosis for Advanced Gastric Cancer in an Older Patient].","authors":"Shinsuke Katsuyama, Toru Masuzawa, Keijiro Sugimura, Kiminori Yanagisawa, Go Shinke, Mitsuru Kinoshita, Ryo Ikeshima, Masayuki Hiraki, Yoshiaki Ohmura, Taishi Hata, Yutaka Takeda, Kohei Murata","doi":"","DOIUrl":"","url":null,"abstract":"An 85-year-old female underwent an upper gastrointestinal endoscopy revealed a type 4 tumor extending from the lesser curvature to the antecubital area, and stenosis of the pyloric lesion. Histology of the biopsy sample showed adenocarcinoma (tub2). CT revealed thickening of the stomach wall and numerous enlarged lymph nodes. Laparoscopic total gastrectomy, D2 dissection, Roux-en-Y reconstruction, and enterostomy were performed. After resection, the jejunum was removed from the abdominal cavity and transected 25 cm from the ligament of Treitz. An R anastomosis was created 10 cm from the anal side to the esophagojejunostomy anastomosis, and an enterocutaneous fistula tube was inserted from the blind end 10 cm from the R anastomosis. Laparoscopic esophagojejunostomy was performed using the overlap method. The enterocutaneous fistula was guided laparoscopically from the left costal region. Postoperatively, the patient was maintained on a diet with nutritional management via an enterostomy. No postoperative or enterostomy-related complications were observed. The postoperative course was uneventful and the patient was discharged from the hospital on the postoperative day 22. There was no deterioration in the nutritional status after discharge. Pathology results showed Stage Ⅳ, pT4aN3bM1. The patient did not receive chemotherapy per her request.","PeriodicalId":35588,"journal":{"name":"Japanese Journal of Cancer and Chemotherapy","volume":"52 4","pages":"323-325"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143989231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[A Young Male Case of Rectosigmoid Adenocarcinoma with Diffuse Peritoneal Metastasis Managed with Palliative Care and Cell-Free and Concentrated Ascites Reinfusion Therapy to Initiate and Transit to Outpatient Systemic Chemotherapy]. [1例年轻男性直肠乙状结肠腺癌伴弥漫性腹膜转移，姑息治疗和无细胞和浓缩腹水回输治疗开始并过渡到门诊全身化疗]。

Japanese Journal of Cancer and Chemotherapy Pub Date : 2025-04-01

Yozo Suzuki, Masakazu Ikenaga, Kiyotaka Hagihara, Katsunori Matsushita, Toshiki Noma, Yasufumi Sato, Yoshitomo Yanagimoto, Masafumi Yamashita, Junzo Shimizu, Tomono Kawase, Kenzo Akagi, Yujiro Kashiwagi, Naohiro Tomita, Hiroshi Imamura

{"title":"[A Young Male Case of Rectosigmoid Adenocarcinoma with Diffuse Peritoneal Metastasis Managed with Palliative Care and Cell-Free and Concentrated Ascites Reinfusion Therapy to Initiate and Transit to Outpatient Systemic Chemotherapy].","authors":"Yozo Suzuki, Masakazu Ikenaga, Kiyotaka Hagihara, Katsunori Matsushita, Toshiki Noma, Yasufumi Sato, Yoshitomo Yanagimoto, Masafumi Yamashita, Junzo Shimizu, Tomono Kawase, Kenzo Akagi, Yujiro Kashiwagi, Naohiro Tomita, Hiroshi Imamura","doi":"","DOIUrl":"","url":null,"abstract":"A 30s-year-old male complaining of abdominal distension and pain was referred to our hospital. The support by palliative care team was initiated soon after emergency admission. Colonoscopic examination revealed a circumferential ulcerated tumor of rectosigmoid and the tumor was diagnosed as an adenocarcinoma. Contrast-enhanced CT revealed multiple enlarged lymph nodes, diffuse peritoneal nodules and massive ascites, which led us to the diagnosis of advanced rectosigmoid cancer. Because bowel obstruction was not observed, early initiation of systemic therapy was planned. Although abdominal pain was alleviated with analgesics including opioids, discomfort from abdominal distension remained. So, we decided to perform cell-free and concentrated ascites reinfusion therapy(CART). To avoid the delay in the initiation of systemic chemotherapy due the adverse effects of CART, the first systemic chemotherapy was followed by CART. After single CART, the abdominal distention resolved without relapse, and seamless transition to outpatient treatment was made. Although the prognosis of colorectal cancer with diffuse peritoneal dissemination is poor, aggressive adoption of palliative therapy including CART may enable the introduction of systemic chemotherapy and the following alleviation of cancer-related symptoms.","PeriodicalId":35588,"journal":{"name":"Japanese Journal of Cancer and Chemotherapy","volume":"52 4","pages":"348-350"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143989233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[A Case of Thyroid Cancer Discovered Incidentally after Breast Cancer Surgery]. 【乳腺癌手术后偶然发现甲状腺癌一例】。

Japanese Journal of Cancer and Chemotherapy Pub Date : 2025-04-01

Kenichi Sakurai, Shuhei Suzuki, Keita Adachi, Tomohiro Hirano, Hitomi Kubota, Ayaka Sakamoto, Akiko Osakaya, Shigeru Fujisaki, Toshiko Ono, Taiki Tsuji

{"title":"[A Case of Thyroid Cancer Discovered Incidentally after Breast Cancer Surgery].","authors":"Kenichi Sakurai, Shuhei Suzuki, Keita Adachi, Tomohiro Hirano, Hitomi Kubota, Ayaka Sakamoto, Akiko Osakaya, Shigeru Fujisaki, Toshiko Ono, Taiki Tsuji","doi":"","DOIUrl":"","url":null,"abstract":"The patient was a 51-year-old woman. A left breast tumor was detected during a health checkup and the patient was referred to our hospital. Upon arrival, a mobile mass measuring 17 mm in diameter was palpable in the CD region of the left breast. The mammogram showed a sawtooth mass. Ultrasonography revealed a hypoechoic mass with abundant blood flow. Needle biopsy revealed invasive ductal carcinoma. Systemic examination revealed masses in both thyroid lobes, and a fine-needle aspiration cytology diagnosis showed it to be benign. A left circular mastectomy and sentinel lymph node biopsy were performed. Pathological examination revealed a resection margin negative, ER negative, PgR negative, HER2 negative invasive ductal carcinoma, with a tumor diameter of 20 mm and 17.2% Ki-67 positivity. Thirty months after surgery, the left thyroid tumor showed a tendency to grow, and fine-needle aspiration cytology was performed again, which revealed a papillary carcinoma. A left thyroid lobectomy and lymph node dissection were performed. Pathological examination revealed that the patient had papillary thyroid cancer, T1aN0M0=Stage Ⅰ(<55y). Currently, 3 years after surgery, there is no evidence of metastasis or recurrence of either cancer.","PeriodicalId":35588,"journal":{"name":"Japanese Journal of Cancer and Chemotherapy","volume":"52 4","pages":"339-341"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144022445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0