Victor Sudário Takahashi, Thiago Ribeiro Dos Santos, Márcio Luís Duarte
{"title":"Pronator Teres Syndrome - Case Report with Imaging Tests Diagnosis.","authors":"Victor Sudário Takahashi, Thiago Ribeiro Dos Santos, Márcio Luís Duarte","doi":"10.14712/23362936.2025.8","DOIUrl":"10.14712/23362936.2025.8","url":null,"abstract":"<p><p>Pronator teres syndrome is characterized by compression of the median nerve, leading to dysfunction of the affected limb. Median nerve entrapment causes paresthesia, changes in sensitivity, and loss of strength in the fingers, in addition to causing loss of hand dexterity. The diagnosis of pronator teres syndrome is complicated, due to its similarity with other neuropathies of the median nerve. So, it is important to emphasize the need for a physical examination together with imaging tests, especially ultrasound, for its correct diagnosis. We report the case of a 28-year-old woman who complained of tingling for ten years in the proximal third of the left forearm at rest that worsens on exertion and weakness if not moving. On physical examination, she has no limitation of movement but refers to a feeling of weakness and numbness in his forearm. Ultrasonography demonstrates compression of the median nerve between the ulnar and humeral heads of the pronator teres muscle, a finding confirmed by magnetic resonance imaging and electroneuromyography. The patient was treated with physiotherapy presenting improvement of symptoms after 45 days.</p>","PeriodicalId":35490,"journal":{"name":"Prague medical report","volume":"126 1","pages":"42-45"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143538093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ivan Skliar, Maryna Kryvtsova, Yevhen Kostenko, Marianna Savenko
{"title":"Biofilm-forming Ability of Anaerobic Bacterial Strains Isolated from Patients Diagnosed with Periodontitis.","authors":"Ivan Skliar, Maryna Kryvtsova, Yevhen Kostenko, Marianna Savenko","doi":"10.14712/23362936.2025.22","DOIUrl":"https://doi.org/10.14712/23362936.2025.22","url":null,"abstract":"<p><p>Bacterial biofilms represent the primary causative agents of pathogenic processes within the oral cavity. Biofilm microorganisms exhibit heightened resistance to adverse environmental factors. The objective of this study was to ascertain the biofilm-forming potential of clinical strains of anaerobic microorganisms isolated from the periodontal pocket of patients diagnosed with periodontitis. The study of biofilm formation was carried out by the method (Djordjevic et al., 2002) using flat-bottomed 96-well polystyrene microtitration plates. Biofilm formation was determined by staining with 0.1% crystal violet. The study utilised clinical strains isolated from the periodontal pocket of 61 patients diagnosed with grade III chronic periodontitis. Of these, 30 strains belonging to three bacterial species were selected for further analysis: Porphyromonas asaccharolytica, Slackia exigua, and Schaalia odontolytica. Among the Porphyromonas asaccharolytica strains, 80% formed biofilm; the figure for Slackia exigua was 90%, and for Schaalia odontolytica - 80%. In total, 25 strains were capable of biofilm formation. The results indicate that the isolated strains of Porphyromonas asaccharolytica, Slackia exigua, and Schaalia odontolytica exhibited a significant capacity for biofilm formation (83.3% of the strains formed biofilm), particularly Slackia exigua strains, which exhibited the highest number of strains with high biofilm formation ability - 5 (16.6%). It is also noteworthy that these microorganisms exhibited a moderate persistence frequency (16.4% each), of the total sample of microbial biocenoses from inflammatory periodontal soft tissue areas.</p>","PeriodicalId":35490,"journal":{"name":"Prague medical report","volume":"126 3","pages":"144-150"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145087530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Dual Roots of Origin of Inferior Alveolar Nerve and \"Vagal Ansa\" Cervicalis: Surgical and Anaesthetic Implications.","authors":"Dibakar Borthakur, Arthi Ganapathy, Kamalesh Saravanan, Jayanta Biswas, Saroj Kaler Jhajhria","doi":"10.14712/23362936.2025.28","DOIUrl":"https://doi.org/10.14712/23362936.2025.28","url":null,"abstract":"<p><p>During routine cadaveric dissection for undergraduate medical teaching, we observed dual roots of origin of the inferior alveolar nerve (IAN) on the right infratemporal fossa in an elderly male cadaver. The IAN originated by two roots encircling the second part of the maxillary artery (MA). The superior root of the ansa cervicalis (AC) originated from the ipsilateral vagus nerve and two independent muscular branches of the right vagus provided additional innervations to the anterior neck muscles. Awareness about the dual roots of origin of IAN is imperative for anaesthesiologists and dentists, while administering local anaesthesia. A prior knowledge about the vagal origin of AC is essential to prevent iatrogenic damage during surgeries.</p>","PeriodicalId":35490,"journal":{"name":"Prague medical report","volume":"126 3","pages":"171-174"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145087536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Unveiling the Enigma: Plasma Cell Leukaemia Presenting with Flower-like Cells, Mimicking Adult T-cell Leukaemia - A Rare Diagnostic Conundrum.","authors":"Anurag Singh, Gyanendra Singh","doi":"10.14712/23362936.2025.25","DOIUrl":"https://doi.org/10.14712/23362936.2025.25","url":null,"abstract":"<p><p>Peripheral plasma cell leukaemia (PCL) is a rare hematologic malignancy that can pose diagnostic challenges due to its resemblance to other conditions such as adult T-cell leukaemia/lymphoma (ATLL) or dissemination lymphoma in peripheral blood. We present a case report of a 40-year-old male with symptoms of fatigue, irregular heartbeat, weight loss, and bone pain, whose peripheral blood examination revealed hyperleukocytosis with atypical lymphoid cells exhibiting flower-shaped nuclei, reminiscent of adult T-cell leukaemia/lymphoma. Further investigations including bone marrow aspiration and biopsy confirmed the diagnosis of primary PCL. Immunophenotyping revealed expression of plasma cell antigens CD38 and CD138. This case underscores the importance of recognizing morphological variants and employing comprehensive immunophenotypic analysis for accurate diagnosis of PCL, especially when atypical nuclear features mimic other hematologic malignancies.</p>","PeriodicalId":35490,"journal":{"name":"Prague medical report","volume":"126 3","pages":"159-161"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145087542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Federica Masino, Laura Eusebi, Manuela Montatore, Giuseppe Maria Andrea D'Arma, Giuseppe Sortino, Lucia Pitoni, Alessandra Filosa, Giuseppe Guglielmi
{"title":"Imaging Features of Prostate Sarcoma: A Case Report.","authors":"Federica Masino, Laura Eusebi, Manuela Montatore, Giuseppe Maria Andrea D'Arma, Giuseppe Sortino, Lucia Pitoni, Alessandra Filosa, Giuseppe Guglielmi","doi":"10.14712/23362936.2025.16","DOIUrl":"https://doi.org/10.14712/23362936.2025.16","url":null,"abstract":"<p><p>A 54-year-old man presented to our clinic complaining of painful ejaculation. The patient underwent various imaging modalities, including ultrasound, transrectal ultrasound, prostate magnetic resonance imaging and positron emission tomography/computed tomography that detected a voluminous mass originating from the prostate. Histological examination diagnosed a prostate sarcoma, a rare mesenchymal tumour. This case offers an opportunity to evaluate a rare subtype of prostate cancer and to describe its main imaging features with an educational approach.</p>","PeriodicalId":35490,"journal":{"name":"Prague medical report","volume":"126 2","pages":"96-102"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144650775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ronaldo Celio Mariano, Geraldo Alves Villela Junior, Pedro Henrique Moraes de Menezes, Sabrina Ferreira
{"title":"Adequacy of the Zetaplasty Technique for Closing Extensive Oroantral Communication.","authors":"Ronaldo Celio Mariano, Geraldo Alves Villela Junior, Pedro Henrique Moraes de Menezes, Sabrina Ferreira","doi":"10.14712/23362936.2025.19","DOIUrl":"https://doi.org/10.14712/23362936.2025.19","url":null,"abstract":"<p><p>A buccosinusal fistula consists of a permanent communication between the oral cavity and the sinus. For the treatment of this complication, three modalities can be highlighted: sliding of the vestibular flap, palatal flap, or graft of cheek adipose tissue. Each of these treatment forms has disadvantages, which led to the development of the zetaplasty technique. Patient C.M., a 57-years-old male, sought the Surgery Clinic of the Federal University of Alfenas for the treatment of a broad buccosinusal communication. After anesthesia, a perilesional incision followed by an extended incision anteriorly to expose the alveolar ridge for regularization. Additional relief incisions were executed to mobilize the vestibular and palatal flaps. The proposed technique aims to obtain relief incisions in the vestibular and palatal areas from the freshened wound margins, allowing the sliding of the flaps in the zetaplasty technique. There has been no need for surgical re-intervention up to the present moment.</p>","PeriodicalId":35490,"journal":{"name":"Prague medical report","volume":"126 2","pages":"111-116"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144650760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Modern Trends in Cancer Diagnosis and Treatment: Innovative Aspects.","authors":"Altin Goxharaj, Kushtrim Salihu, Chinara Zhylkichieva, Aigul Matkeeva, Maral Turdumatova","doi":"10.14712/23362936.2025.11","DOIUrl":"https://doi.org/10.14712/23362936.2025.11","url":null,"abstract":"<p><p>The study aims to analyse new methods in the treatment and diagnosis of cancer, as the prevalence of cancer has been growing rapidly over the past 10 years. This study examined and investigated the implementation of novel approaches in molecular diagnostics, precision medicine (focusing on the genetic and molecular characteristics of cancer), immunotherapy (including immune checkpoint inhibitors), radiation therapy (such as intensity-modulated radiation therapy, CyberKnife, brachytherapy, and proton therapy), nanotechnology, tissue engineering, and the application of artificial intelligence. According to the results of the study, it is worth noting that the use of these diagnostic and treatment methods has significant potential in the field of oncology. For example, molecular diagnostics can detect mutations in the cancer process and optimise treatment. Kosovo is actively considering the use of molecular biomarkers to inhibit cell growth, and Albania has introduced a new molecular classification that helps to predict the occurrence of complications. Genetic research in Kyrgyz Republic is studying the impact on the immune system of the tumour, apoptosis and treatment prognosis. Albania is also making parallels in the immune system of pregnancy and endometrial cancer to predict abnormal pregnancy and find new methods of cancer diagnosis and treatment. The problem of this study is the lack of empirical, clinical research and testing, and the toxicity of some diagnostic and treatment methods. Further research should focus on developing new methods of cancer treatment and diagnosis, as well as optimising and improving existing methods through empirical and clinical trials.</p>","PeriodicalId":35490,"journal":{"name":"Prague medical report","volume":"126 2","pages":"63-74"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144650776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hüseyin Döngelli, Baver Kızartıcı, Mustafa Oktay Tarhan, Ebru Özpelit, Osman Nejat Sarıosmanoğlu, Hatice Kübra Taşçı
{"title":"An Infective Endocarditis Case Report Involving Both Native Aortic and Mitral Valves Due to Streptococcus Vestibularis.","authors":"Hüseyin Döngelli, Baver Kızartıcı, Mustafa Oktay Tarhan, Ebru Özpelit, Osman Nejat Sarıosmanoğlu, Hatice Kübra Taşçı","doi":"10.14712/23362936.2025.4","DOIUrl":"10.14712/23362936.2025.4","url":null,"abstract":"<p><p>Infective endocarditis (IE) is a life-threatening disease, with its mortality rate varying depending on the infectious agent. Streptococci are among the most common causes of infective endocarditis. However, Streptococcus vestibularis has rarely been associated with human infections, typically affecting patients with underlying conditions such as immunosuppressive diseases, valve replacement, rheumatic heart disease, and hemodialysis. We present the case of a 26-year-old man who presented with fever, unanticipated weight loss, and fatigue. Although no typical risk factors for infective endocarditis were identified at admission, transesophageal echocardiography revealed a bicuspid aortic valve with calcification, paravalvular aortic abscess formation, and vegetations on the anterior leaflet of the mitral valve. Blood cultures grew S. vestibularis, which was initially sensitive to benzylpenicillin but developed emergent resistance on the third day of the antibiotic treatment. Subsequently, ceftriaxone therapy was initiated, and blood cultures became sterile on day 10. The patient eventually underwent aortic valve replacement. We report the first known case of native aortic and mitral valve endocarditis caused by S. vestibularis, accompanied by a paravalvular abscess around the native aortic valve, in a patient who had no typical risk factors for infective endocarditis, except for a bicuspid aortic valve.</p>","PeriodicalId":35490,"journal":{"name":"Prague medical report","volume":"126 1","pages":"26-29"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143538064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ariff Aizzat Abdul Razak, Wan Mohd Saifuhisam Wan Zain, Wan Azman Wan Norlina
{"title":"Factitiously Low Total Creatine Kinase Activity in Severe Rhabdomyolysis: A Case Series.","authors":"Ariff Aizzat Abdul Razak, Wan Mohd Saifuhisam Wan Zain, Wan Azman Wan Norlina","doi":"10.14712/23362936.2025.26","DOIUrl":"https://doi.org/10.14712/23362936.2025.26","url":null,"abstract":"<p><p>Factitiously low total creatine kinase (CK) activity can occur in severe rhabdomyolysis, potentially causing misdiagnosis and inappropriate patient management. We hereby describe 2 cases of severe rhabdomyolysis with falsely low total CK activity. Case 1 was a 61-year-old lady with underlying diabetes mellitus diagnosed with severe rhabdomyolysis secondary to severe pneumonia. Case 2 was a 77-year-old man with underlying diabetes mellitus diagnosed with severe rhabdomyolysis secondary to recurrent pyogenic spondylodiscitis. Both cases showed unexpectedly low total CK activity (<7 U/l N: 26-192 U/l). Post-dilution procedures showed markedly elevated total CK activity for case 1 (18,364 U/l [1:11]) and case 2 (15,217 U/l [1:11]). Unfortunately, both patients succumbed despite optimized medical treatment due to multi-organ failures. Measurement of CK in blood is considered as a diagnostic marker for rhabdomyolysis and its severity. Most of the laboratory nowadays measures total CK activity using enzymatic coupled with spectrophotometry method. However, substrate depletion can occur in severe rhabdomyolysis in which creatine phosphate is consumed by high concentration of CK in sample before the kinetic measurement is initiated, leading to factitiously low total CK activity. Sample dilution can be done to obtain the accurate total CK activity, avoiding result reporting error and possibility misdiagnosis of rhabdomyolysis. Good communication between clinical and laboratory personnel is vital to prevent the error and safeguard patient management.</p>","PeriodicalId":35490,"journal":{"name":"Prague medical report","volume":"126 3","pages":"162-166"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145087565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pedro Henrique Moraes de Menezes, Maria Clara Corrêa de Almeida Teixeira, Cleone de Fátima Oliveira Neder Fernandes, Marden Oliveira Bastos, Marina Reis Oliveira, Ronaldo Celio Mariano
{"title":"Use of Marsupialization as a Definitive Treatment for Large-sized Dentigerous Cysts in a Patient with Mucopolysaccharidosis Type I.","authors":"Pedro Henrique Moraes de Menezes, Maria Clara Corrêa de Almeida Teixeira, Cleone de Fátima Oliveira Neder Fernandes, Marden Oliveira Bastos, Marina Reis Oliveira, Ronaldo Celio Mariano","doi":"10.14712/23362936.2024.22","DOIUrl":"10.14712/23362936.2024.22","url":null,"abstract":"<p><p>The correct diagnosis is fundamental for the appropriate treatment to be employed in a particular pathology. The best treatment is not the one that solves only local problems, fragmenting the patient, and therefore, it is necessary to integrate the entire systemic condition of the individual before initiating any local treatment. This context inevitably requires dentistry to participate in a multidisciplinary approach, where the role of the dentist is expanded in concepts that encompass ethics, human dignity, and professional valorization. This article describes a clinical case of a patient with mucopolysaccharidosis type I, whose treatment of cystic lesions present in the mandible was exclusively performed through marsupialisation. The objective of this study is to demonstrate, within the complexity of this rare syndrome, the difficulties of diagnosis and the need for evaluation of the patient beyond the limits of the oral cavity, as well as to report two cases of large dentigerous cysts, surgically treated conservatively through marsupialisation, without the need for re-approach for enucleation and without recurrences over a 20-year period.</p>","PeriodicalId":35490,"journal":{"name":"Prague medical report","volume":"125 3","pages":"239-255"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142018960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}