Prague medical report最新文献_第2页

Coracoclavicular Joint Arthrosis - An Uncommon Cause of Shoulder Pain. 肩锁关节关节病--肩部疼痛的一个不常见原因。

Prague medical report Pub Date : 2024-01-01 DOI: 10.14712/23362936.2024.15

Natã Nascimento de Jesus Graça, Márcio Luís Duarte

引用次数: 0

Gorlin-Goltz Syndrome - A Rare Case Entity in Young Child. 戈林-戈尔茨综合征--幼儿中的罕见病例。

Prague medical report Pub Date : 2024-01-01 DOI: 10.14712/23362936.2024.7

Shovita Mondal, Nikil Kumar Jain, Abhishek Dutta, Nishant, Abhijit Dutta, Moushumi Shil, Suman Sen

引用次数: 0

A Curious Case of Clear Cell Morphology in a Patient with Lung Cancer: Diagnostic Challenges. 肺癌患者透明细胞形态的奇特病例：诊断难题。

Prague medical report Pub Date : 2024-01-01 DOI: 10.14712/23362936.2024.12

Alyssa Bonnier, Mufaddal Najmuddin, Michael D Curry, Anum Nida, Biplab K Saha

{"title":"A Curious Case of Clear Cell Morphology in a Patient with Lung Cancer: Diagnostic Challenges.","authors":"Alyssa Bonnier, Mufaddal Najmuddin, Michael D Curry, Anum Nida, Biplab K Saha","doi":"10.14712/23362936.2024.12","DOIUrl":"10.14712/23362936.2024.12","url":null,"abstract":"An 82-year-old woman with COPD presented to the emergency department with cough, increasing sputum production, wheezing, and worsening shortness of breath for two weeks. On imaging studies, the patient was found to have a right upper lobe spiculated nodule and an endobronchial lesion with near total occlusion of the right lower lobe bronchus with sub-segmental atelectasis. Bronchoscopy with EBUS-TBNA of subcarinal and right hilar lymph nodes revealed lung cancer with clear cell phenotype. Given the predominance of clear cell morphology, the diagnosis of metastatic renal or ovarian cancer was entertained. However, there was no evidence of renal or ovarian lesions on the PET-CT scan, ruling out the possibility. Salivary gland type lung cancer (STLC), which is responsible for less than 1% of all lung cancer cases in adults, was also considered. The two distinct STLCs that may have similar morphologic appearances are hyalinizing clear cell carcinoma (HCCC) and mucoepidermoid carcinoma (MEC). The other type of tumour in the lung that demonstrates a clear cell phenotype is perivascular epithelioid cell neoplasms or PEComa, which are mesenchymal in origin. Immunohistochemical staining was strongly positive for p63, CK5/6, CK7, CK-LMW, and negative for TTF-1, Napsin A, p16, and CK20. Additional staining, including HMB-45, S-100, and mucicarmine, were also negative. Next-generation sequencing for the salivary gland fusion panel, including EWSR1-ATF1 fusion and EWSR1 gene rearrangement for HCCC and MAML2 gene rearrangements for MEC, was negative. She was diagnosed with non-small cell lung cancer favouring squamous cell carcinoma with clear cell phenotype, a rare entity.","PeriodicalId":35490,"journal":{"name":"Prague medical report","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140959319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Weight-bearing Ultrasound to Diagnose Talar Dislocation Causing Tarsal Tunnel Syndrome. 负重超声波诊断引起跗骨隧道综合症的距骨脱位。

Prague medical report Pub Date : 2024-01-01 DOI: 10.14712/23362936.2024.17

Márcio Luís Duarte, Mayara Oliveira da Silva, Ocacir de Souza Reis Soares, Norma Sueli Albino Moreira, Eduardo Kenzo Arie

引用次数: 0

Accessory Flexor Carpi Ulnaris Muscle in Humans: A Rare Anatomical Case with Clinical Considerations. 人类的拇外侧肌：一个罕见的解剖病例及临床考虑因素。

Prague medical report Pub Date : 2024-01-01 DOI: 10.14712/23362936.2024.16

Dibakar Borthakur, Arthi Ganapathy, Mohammed Ahmed Ansari, Ritu Sehgal

{"title":"Accessory Flexor Carpi Ulnaris Muscle in Humans: A Rare Anatomical Case with Clinical Considerations.","authors":"Dibakar Borthakur, Arthi Ganapathy, Mohammed Ahmed Ansari, Ritu Sehgal","doi":"10.14712/23362936.2024.16","DOIUrl":"10.14712/23362936.2024.16","url":null,"abstract":"Anatomical variations of the forearm flexor muscles are occasionally encountered. Though usually observed incidentally during autopsies or imaging studies, they may at times cause concern due to associated clinical symptoms. This report presents a case of unilateral accessory flexor carpi ulnaris (AFCU) muscle observed in a human male cadaver aged 78 years. During routine cadaveric dissection, an anomalous AFCU muscle was observed in the left forearm of a human male cadaver aged 78 years. Standard institutional guidelines pertaining to the use of human cadaver for teaching and research were followed. A thorough literature review about the flexor carpi ulnaris (FCU) through the PubMed, Embase and Google scholar databases was undertaken, using the keywords - accessory flexor carpi ulnaris muscle, aberrant flexor carpi ulnaris muscle and anatomical variation of flexor carpi ulnaris muscle. Relevant gross anatomical findings were recorded and photographed. AFCU was identified on the medial aspect of the distal third of the left forearm. The AFCU was found originating from the ante-brachial fascia and the fascia covering the FCU on the left forearm, forming a small separate belly deep to the main muscle. It terminated as a thin tendon running alongside the hypothenar muscles and attached distally to the base of the proximal phalanx of the little finger. The AFCU was found to be innervated by a branch of the ulnar nerve. Awareness about the rare AFCU muscle is clinically important as a possible cause of ulnar nerve compression but also as a possible graft in reconstruction surgeries.","PeriodicalId":35490,"journal":{"name":"Prague medical report","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140959475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Severe and Fatal Type A Aortic Dissection in an Adult with a Repaired Tetralogy of Fallot. 一名法洛氏四联症修复成人的严重致命 A 型主动脉夹层。

Prague medical report Pub Date : 2024-01-01 DOI: 10.14712/23362936.2024.11

Manuela Montatore, Federica Masino, Vincenzo Signorile, Marina Balbino, Ruggiero Tupputi, Giuseppe Guglielmi

引用次数: 0

Raised First Trimester Thyroid Peroxidase Antibodies May Predict First Trimester Miscarriage: A Case Control Study. 怀孕头三个月甲状腺过氧化物酶抗体升高可预测怀孕头三个月流产：病例对照研究。

Prague medical report Pub Date : 2024-01-01 DOI: 10.14712/23362936.2024.3

Boniface Ago, Enya Okpani, Sylvester Abeshi, Lawson Ekpe

{"title":"Raised First Trimester Thyroid Peroxidase Antibodies May Predict First Trimester Miscarriage: A Case Control Study.","authors":"Boniface Ago, Enya Okpani, Sylvester Abeshi, Lawson Ekpe","doi":"10.14712/23362936.2024.3","DOIUrl":"10.14712/23362936.2024.3","url":null,"abstract":"Miscarriages constitute a significant aspect of failed pregnancies and a source of worry for the patient and caregiver. Some of the causes of miscarriages remain unknown. Immunological conditions such as thyroid autoimmunity could play significant roles. Our objective was to determine the relationship between raised thyroid peroxidase antibodies and first trimester miscarriages in a low resource setting. This was a case control study at the Gynaecological Clinic of the University of Calabar Teaching Hospital, Nigeria; from 14th February 2020 to 13th January 2021, involving 145 cases who had first trimester miscarriages, and their matched controls who had apparently normal pregnancies, at same gestational ages. Sera of venous blood from both participants and controls were analysed for thyroid peroxidase antibodies using enzyme-linked immunosorbent assay, and analysed using SPSS version 20, and GraphPad Prism 8.4.3 statistical software. Being a civil servant and low social status had significant odds for first trimester miscarriage. Raised thyroid peroxidase antibodies in the first trimester had 10-fold odds for miscarriage. Odds ratio 10.34, 95% CI: 3.22 to 32.98, P-value = 0.0001. The test had a sensitivity of 89.66% and specificity of 54.41%. The positive predictive value was 17.93%, while the negative predictive value was 97.93% and a likelihood ratio of 1.966. Rising thyroid peroxidase antibodies in early pregnancy could be a predictor for miscarriage. This is so because patients with raised thyroid peroxidase antibodies in the first trimester had a 10-fold risk of having a first trimester miscarriage.","PeriodicalId":35490,"journal":{"name":"Prague medical report","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139913592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Giant Scrotal Neurofibroma in a Child Masquerading as Filariasis: Uncommon Presentation of a Common Disease. 伪装成丝虫病的儿童巨大阴囊神经纤维瘤：一种常见疾病的罕见表现。

Prague medical report Pub Date : 2024-01-01 DOI: 10.14712/23362936.2024.5

Anurag Singh, Gyanendra Singh, Anuragani Verma, Yogendra Narayan Verma

引用次数: 0

Ruptured Liver Abscess Post Severe COVID-19 Infection: A Case Report. 严重 COVID-19 感染后的肝脓肿破裂：病例报告。

Prague medical report Pub Date : 2024-01-01 DOI: 10.14712/23362936.2024.25

Mohd Firdaus Mohd Isa, Faiz Najmuddin Ghazi, Siti Rahmah Hashim Isa Merican, Ahmad Zuraimi Zulkifli, Premjeet Singh

引用次数: 0

Genetic Variations of Angiotensinogen, Angiotensin Converting Enzyme, and Angiotensin Type 1 Receptor with the Risk of Pulmonary Tuberculosis. 血管紧张素原、血管紧张素转换酶和血管紧张素 1 型受体的基因变异与肺结核的风险。

Prague medical report Pub Date : 2024-01-01 DOI: 10.14712/23362936.2024.1

Hamidreza Kouhpayeh, Mohammad Naderi, Zahra Mohammadghasemipour, Gholamreza Bahari, Nastaran Elahian, Mohsen Taheri, Mohammad Hashemi

{"title":"Genetic Variations of Angiotensinogen, Angiotensin Converting Enzyme, and Angiotensin Type 1 Receptor with the Risk of Pulmonary Tuberculosis.","authors":"Hamidreza Kouhpayeh, Mohammad Naderi, Zahra Mohammadghasemipour, Gholamreza Bahari, Nastaran Elahian, Mohsen Taheri, Mohammad Hashemi","doi":"10.14712/23362936.2024.1","DOIUrl":"10.14712/23362936.2024.1","url":null,"abstract":"There is little data regarding the impact of renin-angiotensin system (RAS) gene polymorphisms on tuberculosis. The current study designed to survey the possible association between RAS polymorphisms and the risk of pulmonary tuberculosis (PTB) in a sample of the southeast Iranian population. This case-control study was done on 170 PTB patients and 170 healthy subjects. The AGT rs699 C>T, ACE rs4341 C>G and AT1R rs5186 C>A variants were genotyped using polymerase chain reaction restriction fragment length polymorphism (PCR-RFLP) and ACE rs4646994 (287bp I/D) variant by PCR method. Regarding AT1R rs5186 A>C polymorphism, the findings revealed that AC genotype and C allele significantly decreased the risk of PTB (OR=0.39, 95% CI=0.22-0.67, p=0.001, and OR=0.53, 95% CI=0.25-0.72, p=0.002, C vs. A, respectively). The TC genotype and C allele of AGT rs699 T>C significantly associated with decreased the risk of PTB (OR=0.45, 95% CI=0.28-0.74, p=0.002, TC vs. TT and OR=0.51, 95% CI=0.32-0.80, p=0.005, C vs. T, respectively). The ID genotype of ACE 287bp I/D significantly increased the risk of PTB (OR=1.88, 95% CI=1.12-3.17, p=0.017). Our finding did not support an association between ACE rs4341 C>G variant and the risk of PTB. In summary, the findings revealed an association between AT1R rs5186 A>C, AGT rs699 T>C and ACE 287bp I/D polymorphisms and the risk of PTB in a sample of the southeast Iranian population. Further investigation with higher sample sizes and diverse ethnicities are required to confirm our findings.","PeriodicalId":35490,"journal":{"name":"Prague medical report","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139913656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0