Prague medical report最新文献_第2页

Unveiling a Silent Obstructor: Phytobezoar in the Third Duodenal Segment. 揭开无声障碍者的面纱：第三段十二指肠中的植物虫。

Prague medical report Pub Date : 2024-01-01 DOI: 10.14712/23362936.2024.13

Ana Fernanda Muñoz Durán, Juan Alberto Llanos Visbal, Leidy Vanessa Aguirre Carvajal, Juan Daniel Ayala Torres, Nicolás Álvarez Gärtner, Julián Andrés Muñoz Durán

引用次数: 0

Evidence for Therapeutic Drug Monitoring of Atypical Antipsychotics. 非典型抗精神病药物治疗药物监测的证据。

Prague medical report Pub Date : 2024-01-01 DOI: 10.14712/23362936.2024.10

Veronika Krejčí, Irena Murínová, Ondřej Slanař, Martin Šíma

{"title":"Evidence for Therapeutic Drug Monitoring of Atypical Antipsychotics.","authors":"Veronika Krejčí, Irena Murínová, Ondřej Slanař, Martin Šíma","doi":"10.14712/23362936.2024.10","DOIUrl":"https://doi.org/10.14712/23362936.2024.10","url":null,"abstract":"Second-generation antipsychotics (SGAs), also known as atypical antipsychotics, are a newer class of antipsychotic drugs used to treat schizophrenia, bipolar disorder, and related psychiatric conditions. The plasma concentration of antipsychotic drugs is a valid measure of the drug at its primary target structure in the brain, and therefore determines the efficacy and safety of these drugs. However, despite the well-known high variability in pharmacokinetics of these substances, psychiatric medication is usually administered in uniform dosage schedules. Therapeutic drug monitoring (TDM), as the specific method that can help personalised medicine in dose adjustment according to the characteristics of the individual patient, minimizing the risk of toxicity, monitoring adherence, and increasing cost-effectiveness in the treatment, thus seems to be an elegant tool to solve this problem. Non-response to therapeutic doses, uncertain adherence to medication, suboptimal tolerability, or pharmacokinetic drug-drug interactions are typical indications for TDM of SGAs. This review aims to summarize an overview of the current knowledge and evidence of the possibilities to tailor the dosage of selected SGAs using TDM, including the necessary pharmacokinetic parameters for personalised pharmacotherapy.","PeriodicalId":35490,"journal":{"name":"Prague medical report","volume":"125 2","pages":"101-129"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140959553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recurrent Stroke as a Presenting Feature of Takayasu Arteritis in an Adolescent: A Case Report and Literature Review. 作为青少年高安动脉炎表现特征的复发性中风：病例报告与文献综述

Prague medical report Pub Date : 2024-01-01 DOI: 10.14712/23362936.2024.6

Vasiliki Sgouropoulou, Efthymia Vargiami, Maria Kyriazi, Sofia Kafterani, Stella Stabouli, Georgios Tsigaras, Athanasia Anastasiou, Maria Trachana, Dimitrios Zafeiriou

引用次数: 0

An Unusual Etiology of Fluorodeoxyglucose Avid Intrathoracic Lymph Nodes. 胸腔内淋巴结荧光脱氧葡萄糖阳性的不寻常病因。

Prague medical report Pub Date : 2024-01-01 DOI: 10.14712/23362936.2024.8

Alyssa Bonnier, Santu Saha, Adam Austin, Biplab K Saha

引用次数: 0

Longitudinal Study Involving Obesity in Women and Bariatric Surgery: An Electromyographic Approach to the Masseter and Temporal Muscles. 涉及女性肥胖和减肥手术的纵向研究：咬肌和颞肌的肌电图方法。

Prague medical report Pub Date : 2024-01-01 DOI: 10.14712/23362936.2024.30

Carolina Hunger Malek-Zadeh, Marcelo Palinkas, Lígia Moriguchi Watanabe, Wilson Salgado, Paulo Batista de Vasconcelos, Isabela Hallak Regalo, Selma Siéssere, Simone Cecilio Hallak Regalo, Carla Barbosa Nonino

{"title":"Longitudinal Study Involving Obesity in Women and Bariatric Surgery: An Electromyographic Approach to the Masseter and Temporal Muscles.","authors":"Carolina Hunger Malek-Zadeh, Marcelo Palinkas, Lígia Moriguchi Watanabe, Wilson Salgado, Paulo Batista de Vasconcelos, Isabela Hallak Regalo, Selma Siéssere, Simone Cecilio Hallak Regalo, Carla Barbosa Nonino","doi":"10.14712/23362936.2024.30","DOIUrl":"https://doi.org/10.14712/23362936.2024.30","url":null,"abstract":"This longitudinal study was aimed to evaluate the electromyographic activity (EMG) of the masticatory muscles during mandibular tasks in women with grade II and III obesity, who were eligible for bariatric surgery. Twenty-one patients were followed up for 3 and 6 months after the Roux-en-Y gastric bypass. The EMG included analyses of the masseter and temporalis muscles during rest, right and left laterality, protrusion, and dental clenching at maximal voluntary contraction with and without parafilm. Data were tabulated and submitted for statistical analysis using the repeated measures test (P<0.05) with the Bonferroni post-test. Significant differences were observed between the right temporal muscle during maximal voluntary contraction (P=0.003) and maximal voluntary contraction with Parafilm M for the right masseter (P=0.01), left masseter (P=0.03), right temporal (P=0.002), and left temporal (P=0.03) muscles. There was gradual decrease in the resting EMG of the masticatory muscles 6 months after surgery. There was an increase in the EMG of the muscles that are the most active in the neuroanatomical movements of laterality and protrusion 6 months after surgery. There was an increase in EMG in maximal voluntary contraction with and without parafilm, 3 and 6 months after surgery. This study suggests that women with severe obesity who underwent bariatric surgery had better functional results of the masticatory muscles 3 and 6 months after the procedure, which is an important parameter in surgical planning, functional recovery, and nutritional status.","PeriodicalId":35490,"journal":{"name":"Prague medical report","volume":"125 4","pages":"339-349"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142751881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cerebral Arterial and Venous Air Embolism Following Removal of Percutaneous Sheath Introducer. 移除经皮鞘导入器后的脑动脉和静脉空气栓塞。

Prague medical report Pub Date : 2024-01-01 DOI: 10.14712/23362936.2024.24

Sana Ghalib, Biplab K Saha, Hau Chieng, Scott H Beegle

引用次数: 0

Laryngotracheoesophageal Cleft Type IV in a Preterm Neonate. A Case Report and Literature Review. 早产新生儿喉气管食管裂孔 IV 型。病例报告与文献综述。

Prague medical report Pub Date : 2024-01-01 DOI: 10.14712/23362936.2024.4

Rozeta Sokou, Anastasia Batsiou, Aikaterini Konstantinidi, Paschalia Kopanou-Taliaka, Marina Tsaousi, Maria Lampridou, Evangelia-Filothei Tavoulari, Konstantinos Mitropoulos, Paraskevi Liakou, Stamatina Willadara-Gamage, Petros V Vlastarakos, Zoi Iliodromiti, Theodora Boutsikou, Nicoletta Iacovidou

{"title":"Laryngotracheoesophageal Cleft Type IV in a Preterm Neonate. A Case Report and Literature Review.","authors":"Rozeta Sokou, Anastasia Batsiou, Aikaterini Konstantinidi, Paschalia Kopanou-Taliaka, Marina Tsaousi, Maria Lampridou, Evangelia-Filothei Tavoulari, Konstantinos Mitropoulos, Paraskevi Liakou, Stamatina Willadara-Gamage, Petros V Vlastarakos, Zoi Iliodromiti, Theodora Boutsikou, Nicoletta Iacovidou","doi":"10.14712/23362936.2024.4","DOIUrl":"10.14712/23362936.2024.4","url":null,"abstract":"We present a case of a preterm neonate with a type IV laryngo-tracheo-oesophageal cleft, an uncommon congenital malformation, resulting from the failure of separation of the trachea and the oesophagus during fetal development, often associated with other deformities as well. Data in the literature shows that the long-term morbidity from the entity has declined over the last decades, even though prognosis remains unfavourable for types III and IV. This report emphasizes the complex issues neonatologists are faced with, when treating neonates with this rare disorder in the first days of life, what will raise suspicion of this rare medical entity, and that direct laryngoscopy/bronchoscopy finally depicts the exact extension of the medical condition. At the same time extensive evaluation for coexisting congenital anomalies should be performed. For all the above reasons, these neonates should be treated in specialized tertiary pediatric centers for multidisciplinary prompt management, which may improve, the outcome.","PeriodicalId":35490,"journal":{"name":"Prague medical report","volume":"125 1","pages":"47-55"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139913658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rheumatoid Arthritis and Osteoarthritis in Adult Women: A Functional Approach to the Stomatognathic System. 成年女性的类风湿关节炎和骨关节炎：从功能角度看口颌系统。

Prague medical report Pub Date : 2024-01-01 DOI: 10.14712/23362936.2024.20

Danilo Stefani Esposto, Marcelo Palinkas, Mariah Acioli Righetti, Oswaldo Luiz Stamato Taube, Anna Luísa Alves Fernandes, Jéssica Chiaratto, Vitória Ricardo, Fernanda Cristina Toloi Fiori Rufato, Simone Cecilio Hallak Regalo, Selma Siéssere

{"title":"Rheumatoid Arthritis and Osteoarthritis in Adult Women: A Functional Approach to the Stomatognathic System.","authors":"Danilo Stefani Esposto, Marcelo Palinkas, Mariah Acioli Righetti, Oswaldo Luiz Stamato Taube, Anna Luísa Alves Fernandes, Jéssica Chiaratto, Vitória Ricardo, Fernanda Cristina Toloi Fiori Rufato, Simone Cecilio Hallak Regalo, Selma Siéssere","doi":"10.14712/23362936.2024.20","DOIUrl":"10.14712/23362936.2024.20","url":null,"abstract":"Rheumatoid arthritis and osteoarthritis both affect the articular cartilage, and are characterized by signs and symptoms that can affect the functions of the human body. This cross-sectional observational study evaluated electromyographic activity in the masseter and temporalis muscles, molar bite force, and mandibular mobility in adult women with rheumatoid arthritis or osteoarthritis. A total of 42 women were distributed into 3 groups: rheumatoid arthritis group (ARG, n=14); osteoarthritis group (OAG, n=14); and a healthy control group (CG, n=14). Electromyography was used to evaluate mandibular tasks at rest, right and left laterality, protrusion, and dental clenching during maximum voluntary contraction, with and without parafilm, and a dynamometer was used to analyse the right and left molar bite forces. A digital caliper was used to measure the range of mandibular movement for maximum mouth opening, right and left laterality, and protrusion. Statistical analyses were performed, including analysis of variance and Tukey's test (P<0.05). Electromyography showed no significant differences between the groups when evaluating the masticatory muscles during the mandibular tasks. Significant difference was observed between the ARG and CG, however, in the maximum right (P=0.007) and left (P=0.02) molar bite forces. Significant difference was observed in the maximum mouth opening of the ARG and OAG groups compared with that of the CG (P=0.009), suggesting that adult women with rheumatoid arthritis or osteoarthritis experience functional alterations in the stomatognathic system, particularly in molar bite force and maximum mouth opening.","PeriodicalId":35490,"journal":{"name":"Prague medical report","volume":"125 3","pages":"220-231"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142018958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of Hematological Markers between Right Ureteral Stone and Acute Appendicitis. 右输尿管结石与急性阑尾炎血液学指标的比较。

Prague medical report Pub Date : 2024-01-01 DOI: 10.14712/23362936.2024.27

Ersin Gökmen, Murat Kars, Selahattin Çalışkan, Yunus Emre Genç, Faruk Arslan, Şakir Karpuz

{"title":"Comparison of Hematological Markers between Right Ureteral Stone and Acute Appendicitis.","authors":"Ersin Gökmen, Murat Kars, Selahattin Çalışkan, Yunus Emre Genç, Faruk Arslan, Şakir Karpuz","doi":"10.14712/23362936.2024.27","DOIUrl":"https://doi.org/10.14712/23362936.2024.27","url":null,"abstract":"Referrals to emergency services are frequently made for acute appendicitis and renal colic. This conundrum of patients with acute appendicitis and right ureteral stones frequently presents itself to emergency physicians. The hematological parameters of patients suffering from acute appendicitis and right ureteral stones were compared in this study. From May 2022 to April 2023 the patients who applied to emergency department were reviewed retrospectively. Of these patients, age, sex, complete blood test results including white blood cell, procalcitonin and C-reactive protein were recorded. The platelet to lymphocyte ratio and the neutrophil to lymphocyte ratio were calculated by dividing the platelet count by the lymphocyte, and the neutrophil count by the lymphocyte count, respectively. We used the receiver operating characteristic curves to assess the diagnostic efficacy of hematological markers. There were 106 patients in the study. The mean age of the patients was 43.83 ± 15.82 years. The significant difference was found for age, white blood cell, neutrophil, lymphocyte, neutrophil to lymphocyte ratio, platelet to lymphocyte ratio and monocyte between groups. The white blood cell and neutrophil to lymphocyte ratio have the biggest area than the other parameters in the receiver operating characteristic curves. Patients with acute appendicitis have a high level of neutrophil to lymphocyte ratio, platelet to lymphocyte ratio than ureteral stones. Further studies are needed to define the diagnostic efficacy of hematological markers for acute appendicitis and ureteral stones.","PeriodicalId":35490,"journal":{"name":"Prague medical report","volume":"125 4","pages":"302-308"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142751880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Outcome after Neuro-interventional Treatment of Intracranial Aneurysm (as a First Treatment Modality). 颅内动脉瘤神经介入治疗（作为第一种治疗方式）后的效果。

Prague medical report Pub Date : 2024-01-01 DOI: 10.14712/23362936.2024.2

Hossein Ghanaati, Aryoobarzan Rahmatian, Mohammad Reza Amiri-Nikpour, Davar Altafi, Morteza Taheri, Seyed Bahaadin Siroos, Madjid Shakiba, Reza Elahi, Mahsa Alborzi Avanaki

{"title":"Outcome after Neuro-interventional Treatment of Intracranial Aneurysm (as a First Treatment Modality).","authors":"Hossein Ghanaati, Aryoobarzan Rahmatian, Mohammad Reza Amiri-Nikpour, Davar Altafi, Morteza Taheri, Seyed Bahaadin Siroos, Madjid Shakiba, Reza Elahi, Mahsa Alborzi Avanaki","doi":"10.14712/23362936.2024.2","DOIUrl":"10.14712/23362936.2024.2","url":null,"abstract":"Endovascular treatment is widely applied as the first-line treatment for intracranial aneurysms and includes simple coiling (SC), stent-assisted coiling (SAC), flow diversion stent, and flow disruption stent. The present study is a retrospective cohort study performed in Imam Khomeini Hospital, Department of Neurovascular Intervention, between March 2016 and March 2021. A total number of 229 patients with intracranial aneurysms who underwent therapeutic intravascular interventions were enrolled, of which 89 were treated with SC, 111 with SAC, 25 with flow diversion stent, and 4 with flow disruption stent. The mean age of the subjects was 51.8±12.6 years, and 51.1% were male. Modified Raymond-Roy classification (MRRC) was used to define the occlusion outcome. The success rate, considered as Class I and Class II of MRRC at treatment time was 89% (94.4% in SC, and 84.7% in SAC), which was increased to 90.9% (94% in SC, 93% in SAC, 69.6% in flow diversion stenting, 100% in flow disruption) at 6-month follow-up, and 84.6% (80.8% in SC, 87.8% in SAC, 78.3% in flow diversion stenting, and 100% in flow disruption) at 12-month follow-up. The mean modified Rankin Scale (mRS) before the procedure was 0.05±0.26 which was increased to 0.22±0.76 after the procedure, 0.22±0.76 at 6 months, and 0.30±0.95 at 12 months (P<0.001). Similar to previous studies, the present study demonstrates that neurovascular intervention can treat ruptured aneurysms as the first therapeutic modality with favourable outcomes. A double-blind, randomized clinical trial is needed to eliminate the confounding factors and better demonstrate the outcome.","PeriodicalId":35490,"journal":{"name":"Prague medical report","volume":"125 1","pages":"15-33"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139913659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0