Clinical Practice and Epidemiology in Mental Health最新文献

{"title":"Validity and Reliability of the Digital Functioning Assessment Short Test (D-FAST) in the Brazilian Sample.","authors":"Silvia Dubou Serafim,&nbsp;Jeferson Ferraz Goularte,&nbsp;Marco Antonio Caldieraro,&nbsp;Flavia Moreira Lima,&nbsp;Giovana Dalpiaz,&nbsp;Francisco Diego Rabelo-da-Ponte,&nbsp;Carla Torrent,&nbsp;Brisa Solé,&nbsp;Eduard Vieta,&nbsp;Adriane Ribeiro Rosa","doi":"10.2174/17450179-v18-e2210121","DOIUrl":"https://doi.org/10.2174/17450179-v18-e2210121","url":null,"abstract":"<p><strong>Background: </strong>The COVID-19 pandemic has caused major disruptions in all aspects of daily functioning, from school and work to interactions with friends and family. The Functioning Assessment Short Test (FAST) is an interviewer-administered scale validated in the psychiatric sample with no previous study assessing its validity and reliability in a digital format. Thus, we aimed to analyse the psychometric properties of the digital version of the FAST and understand the implications of COVID-19 and restrictive measures on functioning.</p><p><strong>Methods: </strong>Data were collected using an online survey. The psychometric properties of the digital FAST were assessed by confirmatory factor analysis, Cronbach's alpha, and discriminant functional by cluster analysis in a community sample.</p><p><strong>Results: </strong>Out of the total sample, 2,543 (84.1%) were female, and the mean (SD) age was 34.28 (12.46) years. The digital FAST retained the six factors structure observed in the original version, with Cronbach's alpha above 0.9. In addition, we showed evidence of discriminant validity by differentiating three clusters of psychosocial functioning. Clinical and demographic differences between groups explained, in part, the heterogeneity of functioning, thus providing support for the construct validity of the instrument.</p><p><strong>Conclusion: </strong>The digital FAST is a simple and easy-to-understand instrument that provides a multidimensional assessment of functioning without the need for an interviewer. Furthermore, our findings may help to better understand the psychosocial implications of the pandemic and the importance of planning specific interventions to rehabilitee the affected group.</p>","PeriodicalId":35447,"journal":{"name":"Clinical Practice and Epidemiology in Mental Health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10156048/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9637314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of Mood Disorders and Associated Factors at the Time of the COVID-19 Pandemic: Potocol for a Community Survey in La Manouba Governorate, Tunisia.","authors":"Uta Ouali,&nbsp;Amina Aissa,&nbsp;Salsabil Rjaibi,&nbsp;Nada Zoghlami,&nbsp;Yosra Zgueb,&nbsp;Amine Larnaout,&nbsp;Mejdi Zid,&nbsp;Imen Kacem,&nbsp;Fatma Charfi,&nbsp;Maria Francesca Moro,&nbsp;Nadia Touihri,&nbsp;Wahid Melki,&nbsp;Hajer Aounallah-Skhiri,&nbsp;Fethi Nacef,&nbsp;Riadh Gouider,&nbsp;Zouhaier El Hechmi,&nbsp;Mauro Giovanni Carta","doi":"10.2174/17450179-v18-e221026-2022-19","DOIUrl":"https://doi.org/10.2174/17450179-v18-e221026-2022-19","url":null,"abstract":"<p><strong>Aims: </strong>The present survey aims to assess the overall mood disorder prevalence and identify associated socio-demographic and clinical factors in a Tunisian community sample, with special attention to the COVID-19 pandemic.</p><p><strong>Background: </strong>Mood disorders are one of the leading causes of all non-fatal burdens of disease, with depression being at the top of the list. The COVID-19 pandemic may have increased the prevalence of mood disorders, especially in Low and Middle-income countries (LMICs) and in vulnerable populations.</p><p><strong>Objective: </strong>1/ Assess point and lifetime prevalence of depressive and bipolar disorders as well as subthreshold bipolarity in a representative population sample of La Manouba governorate and assess treatment patterns for these disorders; 2/Study socio-demographic and clinical correlates of mood disorders 3/ Assess the association between mood disorders and quality of life 4/ Study the impact of the COVID-pandemic on the prevalence of mood disorders 5/ Assess coping mechanisms to the COVID-pandemic and whether these mechanisms moderate the appearance of mood disorders or symptoms since the beginning of the pandemic.</p><p><strong>Methods: </strong>This is a household cross-sectional observational survey to be conducted in La Manouba Governorate in a sample of 4540 randomly selected individuals aged ≥ 15 years. Data collection will be carried out by trained interviewers with clinical experience, through face-to-face interviews and the use of the computer assisted personal interviewing approach (CAPI). The following assessment tools are administered.</p><p><strong>Results: </strong>Structured clinical Interview for DSM IV-TR (Mood disorder section and Screening questions on Anxiety), Mood Disorder Questionnaire (MDQ), Suicide Behaviors Questionnaire-Revised (SBQ), 12-item Short Form Survey (SF-12), the Brief-COPE, and a questionnaire about a headache. In addition, socio-demographic and clinical data will be collected.</p><p><strong>Conclusion: </strong>This will be one of the very few household surveys in a general population sample to assess mental health problems and COVID-19-related variables since the beginning of the pandemic. Through this research, we aim to obtain an epidemiological profile of mood disorders in Tunisia and an estimation of the impact of the COVID-19 pandemic on their prevalence. Results should contribute to improving mental health care in Tunisia.</p>","PeriodicalId":35447,"journal":{"name":"Clinical Practice and Epidemiology in Mental Health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10156032/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9939364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Depression among Older Adults in Indonesia: Prevalence, Role of Chronic Conditions and Other Associated Factors.","authors":"Yvonne Suzy Handajani,&nbsp;Elisabeth Schröder-Butterfill,&nbsp;Eef Hogervorst,&nbsp;Yuda Turana,&nbsp;Antoninus Hengky","doi":"10.2174/17450179-v18-e2207010","DOIUrl":"https://doi.org/10.2174/17450179-v18-e2207010","url":null,"abstract":"<p><strong>Background: </strong>Depression is one of the most common illnesses worldwide, with a prevalence of 5.7% among older adults aged over 60. Depression is a severe health condition that can significantly affect the quality of life.</p><p><strong>Objective: </strong>The objective of this study is to investigate the determinant factors of depression among older adults in Indonesia.</p><p><strong>Methods: </strong>Data of 4236 adults of 60 years old and over were taken from the fifth wave of the Indonesian Family Life Survey (IFLS-5). Sociodemographic and multiple health-related variables collected through interviews and measurements were analyzed. Multivariate logistic regression was used to evaluate depression and its associated factors.</p><p><strong>Results: </strong>The prevalence of depression assessed using ten questions from the Center for Epidemiologic Studies Depression Scale (CES-D 10) was 16.3%. Significant associated factors for depression were moderate and low subjective economic status, living in Java or other regions outside Sumatra and Java, no life satisfaction, self-perceived as having poor health, having dependency (IADL scores), and experienced falls and insomnia. Among chronic conditions, stroke, arthritis, and hearing impairment were also more common in depressed older adults.</p><p><strong>Conclusion: </strong>Predictors of depression identified in this study may be used to help prevent and improve depression in Indonesian older adults, especially those who live on Java. Improvement in healthcare, especially in the prevention and rehabilitation of stroke, arthritis, possible frailty (falls and dependency), hearing impairment, and insomnia, concurrent with early detection of depression in these chronic conditions, may help create a better quality of life among Indonesian older adults.</p>","PeriodicalId":35447,"journal":{"name":"Clinical Practice and Epidemiology in Mental Health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10156049/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9955619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Emotional Contagion Scale and Mental Health Status during the First Wave of COVID-19 Pandemic, National Assessment.","authors":"Samar A Amer,&nbsp;Eman Elsayed Abd-Ellatif,&nbsp;Peter Hughes,&nbsp;Hadi Mahdi Ghazai Al-Enazi,&nbsp;Ahmed AlHasan,&nbsp;Mostafa A Amer,&nbsp;Asma Faleh Alruhaimi,&nbsp;Mohamed Elsayed","doi":"10.2174/17450179-v18-e2208200","DOIUrl":"https://doi.org/10.2174/17450179-v18-e2208200","url":null,"abstract":"<p><strong>Background: </strong>This great pandemic of COVID-19 has been a unique stressor that affected all communities in 2020. This study aims to examine the prevalence of anxiety and depression due to the COVID-19 pandemic in Saudi Arabia and to study the emotional cognition scale in the Kingdom of Saudi Arabia (KSA) in relation to the COVID-19 pandemic.</p><p><strong>Methodology: </strong>A descriptive cross-sectional study was conducted on 857 inhabitants randomly selected from the 13 administrative regions of Saudi Arabia, using a validated self-administrated questionnaire comprising six sections. The collected data were summarized and analyzed.</p><p><strong>Results: </strong>Among the majority of the studied participants, 377 (44.0%) were aged from 35 to less than 50 y. There were 489 (57.1%) females and 368 (42.9%) males, 616 (71.9%) Saudi nationals, 715 (83.4%) university-educated or postgraduate, 619 (72.2%) unmarried and 238 (27.8%) married, and 663 (77.4%) living in areas under partial lockdown. The resultant elevated total depression score was statistically significant (p<0.05) for the following: participants younger than 35y, females, Saudis, those with lower education levels, those who were married, students, those with work suspension during the COVID-19 pandemic, and amongst those who experienced complete lockdown. Among the majority of the studied participants, 355 (41.2%) showed mild depression, and 281(32.6) showed moderate anxiety, and were in the growth zone. In addition, the elevated total anxiety score was statistically significant (p<0.05) amongst the following; younger participants, females, Saudi nationals, those with lower educational levels, those who were unmarried, students, those with telework, and those with no curfew.</p><p><strong>Conclusion: </strong>The adverse mental health effects were more prevalent among particular groups of the population, such as females, adults under 35 years old, students, those with lower educational attainments, and those suffering from chronic illnesses. Anxiety was significantly correlated with depression. The practice of preventive measures, e.g., wearing masks, and social distancing to prevent the spread of COVID-19, may have had psychological benefits during the pandemic.</p><p><strong>Summary: </strong>We assessed the mental health status in Saudi Arabia during the first wave of the COVID-19 pandemic. Mild depression and moderate anxiety were prevalent problems, with many determinants and interrelations. Fear was the most infectious emotion, while happiness was the highest.</p>","PeriodicalId":35447,"journal":{"name":"Clinical Practice and Epidemiology in Mental Health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10156037/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9939366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Depression Among the Caregivers of Breast Cancer Patients and its Association with the Quality of Life.","authors":"Suzie Y Rababa'h,&nbsp;Karem H Alzoubi,&nbsp;Laiali Alquraan,&nbsp;Reema Karasneh,&nbsp;Sayer I Al-Azzam,&nbsp;Nasr Alrabadi","doi":"10.2174/17450179-v18-e2208221","DOIUrl":"https://doi.org/10.2174/17450179-v18-e2208221","url":null,"abstract":"<p><strong>Introduction: </strong>This study investigated the prevalence of depression among the Jordanian caregivers of patients with breast cancer and its effect on their health-related quality of life (QOL).</p><p><strong>Methods: </strong>This was a cross-sectional study with a sample that consisted of 122 caregivers recruited from 2 hospitals in Jordan over 5 months. A validated questionnaire was used to assess the prevalence of depression symptoms and the aspects of QOL among the participants using Beck's Depression Inventory-II score and the 36-Item Survey Form (SF-36) score.</p><p><strong>Results and discussion: </strong>Depression symptoms were revealed in 27.9% of caregivers. Regarding the QOL, the mental health (MH) subscale was considerably associated with caregivers' age (P=0.007). The marital status of caregivers was significantly associated with pain (Bodily Pain BP) (<i>P</i>=0.015), Beck's Depression Inventory (BDI; <i>P</i>=0.009), and social functioning (SF) (<i>P</i>=0.008). The number of caregivers' siblings was considerably associated with MH (<i>P</i>=0.040) subscale. The monthly income of caregivers was associated with BP (<i>P</i>=0.042). The residency of caregivers was considerably connected with role limitations because of emotional problems (RE) (P=0.027) and role limitations due to physical health (RF) (P=0.013) subscales. There was a significant correlation between the existing family history of depression with RF (<i>P</i>=0.009), RE (<i>P</i>=0.005), SF (<i>P</i>=0.003), and energy/fatigue (Vitality VT) (<i>P</i>=0.001) subscales. Furthermore, the physical activity of caregivers was connected with the RF (<i>P</i>=0.030), general health (GH) (<i>P</i>=0.018), RE (<i>P</i>=0.015), and MH (<i>P</i>=0.003) subscales.</p><p><strong>Conclusion: </strong>Around a third of the caregivers revealed depression symptoms. The QOL subscales for these caregivers were connected with various health and social factors, such as age, number of siblings, marital status, monthly income, residency, family history of depression, and physical activity. The evaluation of the mental and physical well-being of caregivers should always be considered and managed to help them to cope with their QOL.</p>","PeriodicalId":35447,"journal":{"name":"Clinical Practice and Epidemiology in Mental Health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10156030/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9575359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mixed Depression: A Survey on Psychopathological, Diagnostic, and Therapeutic Approaches among a Sample of Italian Psychiatrists","authors":"L. Mineo, A. Rodolico, C. Concerto, A. Natale, Manuela Pennisi, M. Tusconi, A. Aguglia, A. Amerio, G. Serafini, M. Amore, E. Aguglia","doi":"10.2174/1745017902117010331","DOIUrl":"https://doi.org/10.2174/1745017902117010331","url":null,"abstract":"\u0000 \u0000 The Diagnostic and Statistical Manual for Mental Disorders (5th edition) introduced the specifier “with Mixed Features” to the diagnosis of Major Depressive Episode to designate the presence of (hypo) manic symptoms as part of the clinical presentation. This change has led to renewed attention on the operational definition, diagnosis, and treatment of Mixed Depression.\u0000 \u0000 \u0000 \u0000 To investigate the diagnostic and therapeutic approaches towards Mixed Depression among a representative sample of Italian psychiatrists.\u0000 \u0000 \u0000 \u0000 Between March and April 2021, 342 psychiatrists working in Italian adult mental health services were invited to participate in an anonymous online survey comprising 32 questions designed to investigate clinical and psychopathological approaches regarding the management of mixed depression in daily psychiatric practice.\u0000 \u0000 \u0000 \u0000 83.74% of participants reported having performed a diagnosis of mixed depression in the last five years, with the majority of respondents affirming that they had not used any diagnostic tool. Only 7,5% of the surveyed psychiatrists considered the DSM-5 criteria to be fully adequate in the description of this clinical entity. The most used pharmacological approach was combined therapy, in particular antipsychotics plus mood stabilizers. For monotherapy, the preferred drugs were Valproate and Quetiapine. Regarding the conceptualization of mood disorders, 199 of the participants chose the Kraepelinian unitary spectrum view; meanwhile, 101 expressed their preference for the binary model.\u0000 \u0000 \u0000 \u0000 Our results suggest a prominent position of mixed depression in the context of mood disorders. Univocal operational criteria and additional research on pharmacological treatment are also needed to ensure the correct recognition and management of mixed depression.\u0000","PeriodicalId":35447,"journal":{"name":"Clinical Practice and Epidemiology in Mental Health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83371278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PTSD and Depression in Healthcare Workers in the Italian Epicenter of the COVID-19 Outbreak.","authors":"Claudia Carmassi,&nbsp;Virginia Pedrinelli,&nbsp;Valerio Dell'Oste,&nbsp;Carlo Antonio Bertelloni,&nbsp;Chiara Grossi,&nbsp;Camilla Gesi,&nbsp;Giancarlo Cerveri,&nbsp;Liliana Dell'Osso","doi":"10.2174/1745017902117010242","DOIUrl":"https://doi.org/10.2174/1745017902117010242","url":null,"abstract":"<p><strong>Background: </strong>Increasing evidence highlights the susceptibility of Healthcare Workers to develop psychopathological sequelae, including Post-Traumatic Stress Disorder (PTSD) and depression, in the current COronaVIrus Disease-19 (COVID-19) pandemic, but little data have been reported in the acute phase of the pandemic.</p><p><strong>Objective: </strong>To explore Healthcare Workers' mental health reactions in the acute phase of the COVID-19 pandemic in the first European epicenter (Lodi/Codogno, Italy), with particular attention to post-traumatic stress and depressive symptoms and their interplay with other psychological outcomes.</p><p><strong>Methods: </strong>74 Healthcare Workers employed at the Azienda Socio Sanitaria Territoriale of Lodi (Lombardy, Italy) were recruited and assessed by means of the <i>Impact of Event Scale- Revised</i>, the <i>Professional Quality of Life Scale-5</i>, the <i>Patient Health Questionnaire-9</i>, the <i>Generalized Anxiety Disorder-7 item</i>, the <i>Resilience Scale</i> and the <i>Work and Social Adjustment Scale</i>. Socio-demographic and clinical variables were compared across three subgroups of the sample (No PTSD, PTSD only, PTSD and depression).</p><p><strong>Results: </strong>A total of 31% of subjects endorsed a diagnosis of PTSD and 28.4% reported PTSD comorbid with major depression. Females were more prone to develop post-traumatic stress and depressive symptoms. Subjects with PTSD and depression groups showed high levels of PTSD, depression, burnout and impairment in functioning. Anxiety symptoms were higher in both PTSD and depression and PTSD groups rather than in the No PTSD group.</p><p><strong>Conclusion: </strong>Our results showed high rates of PTSD and depression among Healthcare Workers and their comorbidity overall being associated with worse outcomes. Current findings suggest that interventions to prevent and treat psychological implications among Healthcare Workers facing infectious outbreaks are needed.</p>","PeriodicalId":35447,"journal":{"name":"Clinical Practice and Epidemiology in Mental Health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728562/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39929573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Screening of Depressive Symptoms in a Russian General Population Sample: A Web-based Cross-sectional Study.","authors":"Andrey Alexandrovich Kibitov,&nbsp;Alexander Sergeevich Rakitko,&nbsp;Evgeniy Dmitirevich Kasyanov,&nbsp;Grigoriy Viktorovich Rukavishnikov,&nbsp;Kira Alexandrovna Kozlova,&nbsp;Valeriy Vladimirovich Ilinsky,&nbsp;Nikolay Grigor'evich Neznanov,&nbsp;Galina Elevna Mazo,&nbsp;Alexander Olegovich Kibitov","doi":"10.2174/1745017902117010205","DOIUrl":"https://doi.org/10.2174/1745017902117010205","url":null,"abstract":"<p><strong>Background and objective: </strong>Web-based screening of depressive symptoms in general non-clinical population can provide better insights into actual prevalence of depressive symptoms and associated risk factors. To study the current prevalence of depressive symptoms in Russian non-clinical population we conducted screening using an online survey based on Depression subscale of Hospital Anxiety and Depression Scale (HADS-D).</p><p><strong>Methods: </strong>The online survey covered 2610 Russian-speaking respondents and included HADS-D, questions about sex, age and presence of cardiovascular diseases (CVD) diagnoses or symptoms in respondents.</p><p><strong>Results: </strong>The proportion of respondents with depressive symptoms, estimated by online HADS-D, was 14.4% (11.5% - at subclinical level, 2.9% - at clinical level). The overall HADS-D score was higher in women (p=0.003), in young individuals under 30 y.o <i>vs</i>. participants over 42 y.o. (p=0.004) and in individuals with self-reported CVD symptoms (p=0.00002). Linear regression analysis showed that self-reported CVD symptoms increase HADS-D score (p<0.001), but male sex (p=0.002) and older age (p<0.001) decrease it. Logistic regression showed that CVD symptoms increase the risk of depressive symptoms by HADS-D (p=0.033, OR=1.29), but older age (p=0.015, OR=0.87) and male sex (as a trend, p=0.052, OR=0.80) decrease this risk.</p><p><strong>Conclusion: </strong>Online survey based on HADS-D showed new patterns of depressive symptoms prevalence in Russian non-clinical population. Depressive symptoms prevalence did not differ between men and women and was higher among young people. The reported association between depressive symptoms and CVD was confirmed.</p>","PeriodicalId":35447,"journal":{"name":"Clinical Practice and Epidemiology in Mental Health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728561/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39627053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Autism and Visual impairment: A First Approach to a Complex Relationship.","authors":"Roberto Pili, Bachisio Zolo, Pericle Farris, Valentina Penna, Simona Valinotti, Gian Pietro Carrogu, Luca Gaviano, Roberta Berti, Lorenzo Pili, Donatella Rita Petretto","doi":"10.2174/1745017902117010212","DOIUrl":"10.2174/1745017902117010212","url":null,"abstract":"<p><p>Since the first half of the 20th century there has been an interest in the study of the relationship between autism and autistic-like clinical features and with visual impairments. Autism Spectrum disorders are one of the more worldwide-studied neurodevelopmental disorder with an increasing prevalence in the last ten years. Visual impairment is a condition which derives from several causes (genetic, constitutional, injuries, nutritional and environmental ones). Again, it is a kind of spectrum and an overarching category, because visual impairments range from refractive errors (myopia, hyperopia, astigmatism), to amblyopia, strabismus, and to partial and total blindness. Since the first study of Keeler (1956) which described autistic-like patterns in five preschool children who were totally blind due to retinopathy of prematurity (ROP), a growing number of researchers addressed the relationship between autism and visual impairment. In this paper we focused on it, aiming to discuss on some lessons learned in this field and to discuss some open questions since the first research in this field.</p>","PeriodicalId":35447,"journal":{"name":"Clinical Practice and Epidemiology in Mental Health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728560/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39627054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Can an Investigation of a Single Gene be Effective in Differentiating Certain Features of the Bipolar Disorder Profile?","authors":"Martina Piras,&nbsp;Alessandra Scano,&nbsp;Germano Orrù,&nbsp;Antonio Preti,&nbsp;Cinzia Marchese,&nbsp;Goce Kalcev","doi":"10.2174/1745017902117010187","DOIUrl":"https://doi.org/10.2174/1745017902117010187","url":null,"abstract":"<p><p>Bipolar disorder (BD) is amongst the most common heritable mental disorders, but the clarification of its genetic roots has proven to be very challenging. Many single nucleotide polymorphisms (SNPs) have been identified to be associated with BD. SNPs in the CACNA1C gene have emerged as the most significantly associated with the disease. The aim of the present study is to provide a concise description of SNP 1006737 variants identified by Real Time PCR and confirm sequencing analysis with the Sanger method in order to estimate the association with BD. The molecular method was tested on 47 Sardinian subjects of whom 23 were found to not be mutated, 1 was found to be a carrier of the homozygous A allele and 23 were found to be carriers of the heterozygous G allele. Moreover, the positive results of the preliminary application suggest that the development of the screener could be extended to the other 5 genetic variables identified as associated with BD.</p>","PeriodicalId":35447,"journal":{"name":"Clinical Practice and Epidemiology in Mental Health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8728559/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39627050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}