Clinical Practice and Epidemiology in Mental Health最新文献

筛选
英文 中文
Managing Problematic Usage of the Internet and Related Disorders in an Era of Diagnostic Transition: An Updated Review. 在诊断转型时代管理有问题的互联网使用和相关障碍:最新综述。
Clinical Practice and Epidemiology in Mental Health Pub Date : 2021-07-14 eCollection Date: 2021-01-01 DOI: 10.2174/1745017902117010061
Bernardo Dell'Osso, Ilaria Di Bernardo, Matteo Vismara, Eleonora Piccoli, Federica Giorgetti, Laura Molteni, Naomi A Fineberg, Calogero Virzì, Henrietta Bowden-Jones, Roberto Truzoli, Caterina Viganò
{"title":"Managing Problematic Usage of the Internet and Related Disorders in an Era of Diagnostic Transition: An Updated Review.","authors":"Bernardo Dell'Osso, Ilaria Di Bernardo, Matteo Vismara, Eleonora Piccoli, Federica Giorgetti, Laura Molteni, Naomi A Fineberg, Calogero Virzì, Henrietta Bowden-Jones, Roberto Truzoli, Caterina Viganò","doi":"10.2174/1745017902117010061","DOIUrl":"10.2174/1745017902117010061","url":null,"abstract":"<p><strong>Introduction: </strong>Problematic Usage of the Internet (PUI) refers to a broad and likely heterogeneous group of Internet-related conditions associated with behavioural disturbances and functional impairment.</p><p><strong>Methods: </strong>Within PUI several conditions have been reported, including Gaming Disorder, Shopping Addiction, Cyberchondria, Gambling Disorder, Cyberpornography Addiction and Cyberbullying. While increasing reports in the field try to define the epidemiologic and clinical boundaries of these conditions, the rapid and continuous evolution of Internet related behaviours as well as their problematic/pathological expressions are often difficult to diagnose, assess, approach with treatment interventions and follow-up.</p><p><strong>Results: </strong>In addition, some of the PUI-related conditions show characteristics of addiction to the Internet as a preferential tool to engage in specific behaviours, while some others exclusively manifest on the Internet, making it necessary to find distinct assessment and treatment pathways.</p><p><strong>Conclusion: </strong>The inclusion of Internet Gaming Disorder in Section III by the DSM-5 and the recognition of Gaming Disorder by the ICD-11 opened the way for a systematic clinical investigation of this and other PUI-related conditions, particularly in terms of preventive and therapeutic strategies. The present article is aimed at offering an updated clinical overview on the main expressions of PUI, focussing on the latest acquisitions in this evolving field.</p>","PeriodicalId":35447,"journal":{"name":"Clinical Practice and Epidemiology in Mental Health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8386084/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39414750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impacts on and Care of Psychiatric Patients during the Outbreak of COVID-19. 新冠肺炎疫情对精神科患者的影响及护理
Clinical Practice and Epidemiology in Mental Health Pub Date : 2021-07-12 eCollection Date: 2021-01-01 DOI: 10.2174/1745017902117010052
Pavarud Puangsri, Vinn Jinanarong, Apichai Wattanapisit
{"title":"Impacts on and Care of Psychiatric Patients during the Outbreak of COVID-19.","authors":"Pavarud Puangsri,&nbsp;Vinn Jinanarong,&nbsp;Apichai Wattanapisit","doi":"10.2174/1745017902117010052","DOIUrl":"https://doi.org/10.2174/1745017902117010052","url":null,"abstract":"<p><p>The outbreak of coronavirus disease (COVID-19) in December 2019 has led to massive lifestyle, economic, and health changes. The COVID-19 pandemic has had broad impacts on psychiatric patients, exacerbating symptoms such as psychosis, depression, and suicidal ideation. Therefore, we aimed to review the psychological impacts of COVID-19 on psychiatric patients and mental healthcare staff and provide practical guidance for medical staff and authorities. The main findings of this review included the impacts of COVID-19 on psychiatric patients and mental health professionals as well as the transformation of mental health care. Greater consideration should be given to the care of patients with psychosis and depression because of their lack of self-care ability, neurocognitive impairment, and impaired immune function. Depressive symptoms can be exacerbated due to several factors, such as economic crises, social isolation, and limited physical activity. Unemployment and financial problems can lead to an increased suicide rate. Consequently, mental healthcare workers' workload can increase, which could lead to burnout and psychological symptoms such as insomnia, depression, and anxiety. A transformation of psychiatric care is needed during the time of the pandemic. While emergency care should be maintained, outpatient care should be limited to decrease viral spread. Shifting care to telemedicine and community-based psychiatry can be helpful. Inpatient services should be adapted by tightening admission criteria, shortening the length of hospital stays, suspending some group activities, limiting visitors, and preparing for quarantine if necessary. Mental healthcare workers can be supported with telecommunication, appropriate work shifts, alternative accommodations, and good communication between the team leader and staff.</p>","PeriodicalId":35447,"journal":{"name":"Clinical Practice and Epidemiology in Mental Health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8386085/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39414749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 19
In Memory of Hagop Akiskal. 纪念Hagop Akiskal。
Clinical Practice and Epidemiology in Mental Health Pub Date : 2021-05-31 eCollection Date: 2021-01-01 DOI: 10.2174/1745017902117010048
Mauro G Carta, Francesc Colom, Andreas Erfurth, Michele Fornaro, Heinz Grunze, Elie Hantouche, Antonio E Nardi, Antonio Preti, Eduard Vieta, Elie Karam
{"title":"In Memory of Hagop Akiskal.","authors":"Mauro G Carta,&nbsp;Francesc Colom,&nbsp;Andreas Erfurth,&nbsp;Michele Fornaro,&nbsp;Heinz Grunze,&nbsp;Elie Hantouche,&nbsp;Antonio E Nardi,&nbsp;Antonio Preti,&nbsp;Eduard Vieta,&nbsp;Elie Karam","doi":"10.2174/1745017902117010048","DOIUrl":"https://doi.org/10.2174/1745017902117010048","url":null,"abstract":"Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy Hospital del Mar, Barcelona, Spain Department of Psychiatry and Psychotherapeutic Medicine, Klinik Hietzing, Vienna, Austria Laboratory of Molecular and Translational Psychiatry, Department of Neuroscience, School of Medicine, University \"Federico II\", Naples, Italy Center for Psychiatry Weinsberg, Klinikum am Weissenhof, Weinsberg, Germany Center for Anxiety and Mood Disorders, Anxiety & Mood Center, 117, Rue de Rennes, Paris 75006, France Institute of Psychiatry,Federal University of Rio de Janeiro,Rio de Janeiro, Brazil Department of Neurosciences, University of Turin, 10124 Turin, Italy Bipolar Disorders Unit, Hospital Clinic, Institute of Neurosciences, University of Barcelona, IDIBAPS, CIBERSAM, Barcelona, Catalonia, Spain Department of Psychiatry and Clinical Psychology, Faculty of Medicine, Balamand University, Beirut, Lebanon","PeriodicalId":35447,"journal":{"name":"Clinical Practice and Epidemiology in Mental Health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8227446/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39173941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
Catatonia Associated with Hyponatremia: Case Report and Brief Review of the Literature. 紧张症伴低钠血症:病例报告及文献综述。
Clinical Practice and Epidemiology in Mental Health Pub Date : 2021-05-24 eCollection Date: 2021-01-01 DOI: 10.2174/1745017902117010026
Vaios Peritogiannis, Dimitrios V Rizos
{"title":"Catatonia Associated with Hyponatremia: Case Report and Brief Review of the Literature.","authors":"Vaios Peritogiannis,&nbsp;Dimitrios V Rizos","doi":"10.2174/1745017902117010026","DOIUrl":"https://doi.org/10.2174/1745017902117010026","url":null,"abstract":"Background: Catatonia is a syndrome of altered motor behavior that is mostly associated with general medical, neurologic, mood and schizophrenia-spectrum disorders. The association of newly onset catatonic symptoms with hyponatremia has been rarely reported in the literature. Case Presentation: We present a rare case of a young female patient with schizophrenia, who presented with catatonic symptoms in the context of hyponatremia due to water intoxication. The symptoms were eliminated with the correction of hyponatremia. There are only a few reports of hyponatremia-associated catatonia in psychiatric and non-psychiatric patients. Sometimes, catatonic symptoms may co-occur with newly onset psychotic symptoms and confusion, suggesting delirium. In several cases, the catatonic symptoms responded to specific treatment with benzodiazepines or electroconvulsive therapy. Conclusion: Hyponatremia may induce catatonic symptoms in patients, regardless of underlying mental illness, but this phenomenon is even more relevant in patients with a psychotic or mood disorder, which may itself cause catatonic symptoms. It is important for clinicians not to attribute newly-onset catatonic symptoms to the underlying psychotic or mood disorder without measuring sodium serum levels. The measurement of sodium serum levels may guide treating psychiatrists to refer the patient for further investigation and appropriate treatment.","PeriodicalId":35447,"journal":{"name":"Clinical Practice and Epidemiology in Mental Health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8227445/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39173939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Strategies for Psychiatric Rehabilitation and their Cognitive Outcomes in Schizophrenia: Review of Last Five-year Studies. 精神分裂症患者的精神康复策略及其认知结果:近五年研究综述。
Clinical Practice and Epidemiology in Mental Health Pub Date : 2021-05-24 eCollection Date: 2021-01-01 DOI: 10.2174/1745017902117010031
Antonio Rampino, Rosa M Falcone, Arianna Giannuzzi, Rita Masellis, Linda A Antonucci, Silvia Torretta
{"title":"Strategies for Psychiatric Rehabilitation and their Cognitive Outcomes in Schizophrenia: Review of Last Five-year Studies.","authors":"Antonio Rampino,&nbsp;Rosa M Falcone,&nbsp;Arianna Giannuzzi,&nbsp;Rita Masellis,&nbsp;Linda A Antonucci,&nbsp;Silvia Torretta","doi":"10.2174/1745017902117010031","DOIUrl":"10.2174/1745017902117010031","url":null,"abstract":"<p><strong>Background: </strong>Cognitive deficits are core features of Schizophrenia, showing poor response to antipsychotic treatment, therefore non-pharmacological rehabilitative approaches to such a symptom domain need to be identified. However, since not all patients with Schizophrenia exhibit the same cognitive impairment profile, individualized rehabilitative approaches should be set up.</p><p><strong>Objectives: </strong>We explored the last five-year literature addressing the issue of cognitive dysfunction response to rehabilitative methodologies in Schizophrenia to identify possible predictors of response and individualized strategies to treat such a dysfunction.</p><p><strong>Conclusion: </strong>A total of 76 studies were reviewed. Possible predictors of cognitive rehabilitation outcome were identified among patient-specific and approach-specific variables and a general overview of rehabilitative strategies used in the last five years has been depicted. Studies suggest the existence of multifaced and multi-domain variables that could significantly predict pro-cognitive effects of cognitive rehabilitation, which could also be useful for identifying individual-specific rehabilitation trajectories over time.An individualized rehabilitative approach to cognitive impairment in Schizophrenia is possible if taking into account both patient and approach specific predictors of outcomes.</p>","PeriodicalId":35447,"journal":{"name":"Clinical Practice and Epidemiology in Mental Health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8227533/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39173940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Fear of COVID-19 among Peruvian People Living in Disadvantaged Communities: A Cross-Sectional Study. 秘鲁贫困社区居民对 COVID-19 的恐惧:一项横断面研究。
Clinical Practice and Epidemiology in Mental Health Pub Date : 2021-04-16 eCollection Date: 2021-01-01 DOI: 10.2174/1745017902117010019
Carlos Sotomayor-Beltran, Hernan Matta-Solis, Rosa Perez-Siguas, Eduardo Matta-Solis, Lourdes Matta-Zamudio
{"title":"Fear of COVID-19 among Peruvian People Living in Disadvantaged Communities: A Cross-Sectional Study.","authors":"Carlos Sotomayor-Beltran, Hernan Matta-Solis, Rosa Perez-Siguas, Eduardo Matta-Solis, Lourdes Matta-Zamudio","doi":"10.2174/1745017902117010019","DOIUrl":"10.2174/1745017902117010019","url":null,"abstract":"<p><strong>Background: </strong>The COVID-19 crisis is fuelling a state of fear among the human population at global level. Especially, those living in informal settlements and slums worldwide have been profoundly impacted by this pandemic. Individuals living in these places are already leading underprivileged lives. Thus, the economic and mental health problems caused by the COVID-19 crisis have further exacerbated their living standards, which has resulted, for instance, in tragedies such as suicides.</p><p><strong>Objective: </strong>In this study, we have sought to identify those individuals most at risk of displaying high levels of fear of COVID-19 in an informal settlement located in the capital city of Peru.</p><p><strong>Methods: </strong>A questionnaire was administered to 449 inhabitants living in the Carmen Alto informal settlement. The questionnaire was made up of two parts: the first one inquired about demographic data and the second part consisted of the Fear of COVID-19 Scale.</p><p><strong>Results: </strong>The demographic variables of age, gender, marital status, educational level, occupation, whether a relative from the household was infected with COVID-19, and whether one of them died of this showed significant differences. It could be observed as well that the groups of females, stable workers, unemployed and those having completed a workforce education are at higher odds of displaying high levels of fear of COVID-19. As expected, the groups that had either a relative infected with COVID-19 or a relative death by this had the highest levels of fear towards the virus.</p><p><strong>Conclusion: </strong>The female participants are more likely to display higher levels of fear of COVID-19 due to the terrible effect that unfavorable events have on them. In the cases of the unemployed and stable workers, their proneness to show high levels of fear towards the virus is because they have lost their incomes, due to the loss of their jobs, and because of fear of infection, respectively. Hence, we hope that this work serves Peruvian (and other) health authorities to develop strategies that help individuals living in informal settlements and are in urgent need of mitigating mental health problems.</p>","PeriodicalId":35447,"journal":{"name":"Clinical Practice and Epidemiology in Mental Health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/bc/40/CPEMH-17-19.PMC8097400.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39036429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Malaysian Women's Experience of Care and Management of Postnatal Depression. 马来西亚妇女产后抑郁症的护理和管理经验。
Clinical Practice and Epidemiology in Mental Health Pub Date : 2021-04-13 eCollection Date: 2021-01-01 DOI: 10.2174/1745017902117010010
Siti R B M Arifin, Helen Cheyne, Margaret Maxwell, Abdilahi Yousuf
{"title":"The Malaysian Women's Experience of Care and Management of Postnatal Depression.","authors":"Siti R B M Arifin,&nbsp;Helen Cheyne,&nbsp;Margaret Maxwell,&nbsp;Abdilahi Yousuf","doi":"10.2174/1745017902117010010","DOIUrl":"https://doi.org/10.2174/1745017902117010010","url":null,"abstract":"<p><strong>Objectives: </strong>Early detection and intervention for Maternal Postnatal Depression (PND) are imperative to prevent devastating consequences for mothers, babies, and families. However, there are no guidelines that explicitly focus on the management of PND in Malaysia. Consequently, it is unclear whether women with PND are receiving proper care and treatment. Therefore, this study aimed to explore Malaysian Women's experience in managing PND symptoms.</p><p><strong>Methods: </strong>A qualitative study was conducted among 33 women attending Maternal and Child Health (MCH) clinics in Kuala Lumpur. Data were obtained through a face-to-face semi-structured interview and analysed using framework analysis.</p><p><strong>Results: </strong>The women considered PND as a personal and temporary issue. Therefore, professional care was deemed unnecessary for them. Additionally, all Malay women considered religious approach as their primary coping strategy for PND. However, this was not the case for most Indian and Chinese women.</p><p><strong>Conclusion: </strong>The findings of this study indicated that women did not acknowledge the roles of Healthcare Practitioners (HCPs) in alleviating their emotional distress.Also, they perceived PND as a personal problem and less serious emotional condition. It is due to this perception that the women adopted self-help care as their primary coping strategy for PND. However, the coping strategy varied between different cultures. These findings underscore the importance of HCPs' proactive action to detect and alleviate PND symptoms as their attitude towards PND may influence Women's help-seeking behaviour.</p>","PeriodicalId":35447,"journal":{"name":"Clinical Practice and Epidemiology in Mental Health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/29/20/CPEMH-17-10.PMC8097402.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39036428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Erratum: Mediterranean Diet and its Benefits on Health and Mental Health: A Literature Review. 勘误:地中海饮食及其对健康和心理健康的益处:文献综述。
Clinical Practice and Epidemiology in Mental Health Pub Date : 2021-03-26 eCollection Date: 2021-01-01 DOI: 10.2174/1745017902117010009
Antonio Ventriglio, Federica Sancassiani, Maria Paola Contu, Mariateresa Latorre, Melanie Di Salvatore, Michele Fornaro, Dinesh Bhugra
{"title":"Erratum: Mediterranean Diet and its Benefits on Health and Mental Health: A Literature Review.","authors":"Antonio Ventriglio, Federica Sancassiani, Maria Paola Contu, Mariateresa Latorre, Melanie Di Salvatore, Michele Fornaro, Dinesh Bhugra","doi":"10.2174/1745017902117010009","DOIUrl":"10.2174/1745017902117010009","url":null,"abstract":"<p><p>[This corrects the article on p. 156 in vol. 16, PMCID: 7536728.].</p>","PeriodicalId":35447,"journal":{"name":"Clinical Practice and Epidemiology in Mental Health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/40/97/CPEMH-17-9.PMC8097401.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39022814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Implementing WHO-Quality Rights Project in Tunisia: Results of an Intervention at Razi Hospital. 在突尼斯实施世卫组织质量权利项目:在Razi医院进行干预的结果。
Clinical Practice and Epidemiology in Mental Health Pub Date : 2021-02-19 eCollection Date: 2021-01-01 DOI: 10.2174/1745017902117010008
Mauro Giovanni Carta, Rym Ghacem, Myriam Milka, Olfa Moula, Nidhal Staali, Uta Uali, Ghassene Boukhari, Monica Mannu, Rym Refrafi, Souha Yaakoubi, Maria Francesca Moro, Marie Baudel, Simon Vasseur-Bacle, Natalie Drew, Michelle Funk
{"title":"Implementing WHO-Quality Rights Project in Tunisia: Results of an Intervention at Razi Hospital.","authors":"Mauro Giovanni Carta,&nbsp;Rym Ghacem,&nbsp;Myriam Milka,&nbsp;Olfa Moula,&nbsp;Nidhal Staali,&nbsp;Uta Uali,&nbsp;Ghassene Boukhari,&nbsp;Monica Mannu,&nbsp;Rym Refrafi,&nbsp;Souha Yaakoubi,&nbsp;Maria Francesca Moro,&nbsp;Marie Baudel,&nbsp;Simon Vasseur-Bacle,&nbsp;Natalie Drew,&nbsp;Michelle Funk","doi":"10.2174/1745017902117010008","DOIUrl":"https://doi.org/10.2174/1745017902117010008","url":null,"abstract":"","PeriodicalId":35447,"journal":{"name":"Clinical Practice and Epidemiology in Mental Health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/5f/06/CPEMH-17-8.PMC7931145.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25478597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of Extrapyramidal Symptoms Associated with Psychotropics Pharmacological Treatments, and Associated Risk Factors. 评估与精神药物治疗相关的锥体外系症状及相关危险因素。
Clinical Practice and Epidemiology in Mental Health Pub Date : 2021-02-16 eCollection Date: 2021-01-01 DOI: 10.2174/1745017902117010001
Dania Abu-Naser, Sara Gharaibeh, Ahmad Z Al Meslamani, Qais Alefan, Renad Abunaser
{"title":"Assessment of Extrapyramidal Symptoms Associated with Psychotropics Pharmacological Treatments, and Associated Risk Factors.","authors":"Dania Abu-Naser, Sara Gharaibeh, Ahmad Z Al Meslamani, Qais Alefan, Renad Abunaser","doi":"10.2174/1745017902117010001","DOIUrl":"10.2174/1745017902117010001","url":null,"abstract":"<p><strong>Background: </strong>Extrapyramidal Symptoms (EPS) are unwanted symptoms commonly originating from the use of certain medications. The symptoms can range from minimal discomfort to permanent involuntary muscular movements. The aims of the study were to examine the incidence of drug-induced extrapyramidal symptoms (di-EPS), associated risk factors, and clinical characteristics.</p><p><strong>Methods: </strong>This is a retrospective, observational study of di-EPS conducted in outpatient clinics of Jordan using the longitudinal health database (Hakeem<sup>®</sup>) for data collection. Patients who received drugs with the risk of EPS during the period 2010-2020 were included and followed. Patients with any of the known underlying conditions that may cause EPS or were currently taking drugs that may mask the symptoms were excluded. Gender and age-matched control subjects were included in the study. The Statistical Package for Social Science (SPSS<sup>®</sup>) version 26 was used for data analysis.</p><p><strong>Results: </strong>The final dataset included 34898 exposed patients and 69796 matched controls. The incidence of di-EPS ranged from 9.8% [Amitriptyline 25mg] to 28.9% (Imipramine 25mg). Baseline factors associated with a significantly higher risk of developing di-EPS were age {HR: 1.1 [95%CI: 0.8-1.2, p=0.003], smoking {HR: 1.7 (95%CI: 1.3-2.2), p=0.02}, tremor history {HR: 7.4 (95%CI: 5.9-8.3), p=.002} and history of taking antipsychotics {HR: 3.9, (95% CI: 2.5-4.6), p=0.001}. Patients taking paroxetine {HR: 8.6 [95%CI: 7.4-9.8], p=.0002},imipramine {HR: 8.3, [7.1-10.5], p=0.01}, or fluoxetine {HR: 8.2 (95%CI: 6.8-9.3), p=.006} had a significantly higher risk of developing di-EPS compared to patients taking citalopram. Myoclonus, blepharospasm, symptoms of the basal ganglia dysfunction, and organic writers' cramp were reported among participants.</p><p><strong>Conclusion: </strong>Patients treated with paroxetine, imipramine, fluoxetine, or clomipramine had a higher risk of developing di-EPS than patients treated with citalopram. The difference in gender was not significantly related to di-EPS development. Whereas age, smoking, and history of taking antipsychotics were significantly associated with di-EPS development.</p><p><strong>Key findings: </strong>• High incidence of drug-induced extrapyramidal symptoms (di-EPS) was reported• Age, smoking, tremor history, and history of taking antipsychotics were risk factors of drug-induced extrapyramidal symptoms.• Patients taking paroxetine, imipramine or fluoxetine had a significantly higher risk of developing di-EPS compared to patients taking citalopram.</p>","PeriodicalId":35447,"journal":{"name":"Clinical Practice and Epidemiology in Mental Health","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/cc/21/CPEMH-17-1.PMC7931155.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25478596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 12
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信