{"title":"A ZIF-82-based nanoreactor for tumor-specific nitric oxide release and enhanced photodynamic therapy under NIR-II imaging guidance.","authors":"Yumin Han, Yuda Wang, Wenxin Zheng, Zulpya Mahmut, Xinyao Zhang, Chunmei Zhang, Xianhong Zheng, Yuanyuan Zhao, Jiao Sun, Biao Dong","doi":"10.1016/j.jcis.2025.139265","DOIUrl":"https://doi.org/10.1016/j.jcis.2025.139265","url":null,"abstract":"<p><p>Cancer remains a critical global health challenge, with conventional treatments often limited by systemic toxicity, therapeutic resistance, and inadequate penetration into deep tumor tissues. To address these issues, we developed UC-ZIF/MC540-an integrated nanoplatform combining Ce<sup>3+</sup>-doped upconversion nanoparticles (UCNPs) with the photosensitizer Merocyanine 540 within a ZIF-82 metal-organic framework. Under 980 nm near-infrared irradiation, the UCNPs emit visible light at 540 nm, activating MC540 to generate reactive oxygen species for photodynamic therapy (PDT). Simultaneously, the ZIF-82 component responds to tumor microenvironmental cues, including acidity, hypoxia, and radiation, to release nitric oxide (NO), which suppresses HSP70 expression and synergistically enhances PDT efficacy. Furthermore, the Ce<sup>3+</sup> doping enhances emission in the NIR-IIb window (1525 nm), facilitating high-resolution deep-tissue imaging and precise tracking of nanoparticle distribution. This multifunctional system enables a combined therapeutic and diagnostic strategy for effective treatment of melanoma and other deep-seated tumors.</p>","PeriodicalId":351,"journal":{"name":"Journal of Colloid and Interface Science","volume":"703 Pt 2","pages":"139265"},"PeriodicalIF":9.7,"publicationDate":"2025-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145342428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Corrigendum to “Hydrodynamic instabilities and interface dynamics of two immiscible liquids driven by a rotating disk” [J. Colloid Interface Sci. 702(Part 2) (2026) 138998]","authors":"Sabrina Nouri , Mohamed Aksouh , Adel Lalaoua","doi":"10.1016/j.jcis.2025.139201","DOIUrl":"10.1016/j.jcis.2025.139201","url":null,"abstract":"","PeriodicalId":351,"journal":{"name":"Journal of Colloid and Interface Science","volume":"703 ","pages":"Article 139201"},"PeriodicalIF":9.7,"publicationDate":"2025-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145306606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
María Queralt-Martín, Laidy M Alvero-Gonzalez, Marcel Aguilella-Arzo, D Aurora Perini, Lucie A Bergdoll, Antonio Alcaraz
{"title":"Interfacial effects break the canonical permeability-selectivity trade-off in biological nanopores.","authors":"María Queralt-Martín, Laidy M Alvero-Gonzalez, Marcel Aguilella-Arzo, D Aurora Perini, Lucie A Bergdoll, Antonio Alcaraz","doi":"10.1016/j.jcis.2025.139266","DOIUrl":"https://doi.org/10.1016/j.jcis.2025.139266","url":null,"abstract":"<p><strong>Hypothesis: </strong>Transport in membrane systems involves a classic trade-off between permeability (how many particles can pass through) and selectivity (the ability to sort specific particles) ruled by the pore size and the inner channel charges. By using interfacial effects from charges on the outer surface of the pore, it is possible to change the channel's conductive properties without altering its physical pore size. This suggests a new way to overcome the permeability-selectivity compromise in unexpected ways.</p><p><strong>Experiments and theoretical analysis: </strong>We perform an exhaustive electrophysiological analysis of the conductive properties of two wide biological ion channels, the bacterial porin OmpF from E. coli and the mitochondrial Voltage Dependent Anion Channel (VDAC), paying attention to the role of membrane lipid charges in the interplay between permeability and selectivity. We examine this interplay using an equivalent circuit model based on the principle of ionic current independence and with numerical simulations derived from Poisson-Nernst-Planck equations based on 3D protein structures at atomic resolution.</p><p><strong>Findings: </strong>We demonstrate that membrane and pore charges do not compensate for each other. Rather, they function as complementary interaction sites giving rise to unique transport characteristics that can enhance simultaneously both permeability and selectivity beyond the predicted upper limit. Traditionally, efforts have concentrated on functionalizing inner channel surfaces; however, our findings highlight how separately modifying outer channel surfaces can enable nanofluidic devices to overcome the permeability-selectivity trade-off.</p>","PeriodicalId":351,"journal":{"name":"Journal of Colloid and Interface Science","volume":"703 Pt 2","pages":"139266"},"PeriodicalIF":9.7,"publicationDate":"2025-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145353170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ruke Sun, Haitao Man, Xiantuo Chen, Jiang Wu, Bin Chen, Zhou Shi, Le Chen, Danzhen Gu, Rui Zhang, Jinbin Zhao
{"title":"Bifunctional modulation of RuF modified CoP nanorod catalysts for efficient overall water splitting.","authors":"Ruke Sun, Haitao Man, Xiantuo Chen, Jiang Wu, Bin Chen, Zhou Shi, Le Chen, Danzhen Gu, Rui Zhang, Jinbin Zhao","doi":"10.1016/j.jcis.2025.139268","DOIUrl":"https://doi.org/10.1016/j.jcis.2025.139268","url":null,"abstract":"<p><p>Cobalt phosphide (CoP) is a promising non-noble metal electrocatalyst for overall water splitting, but its practical application is limited by intrinsically sluggish water dissociation kinetics and insufficient exposure of active sites. To address these challenges, this study proposes a Ru and F synergistic doping strategy to regulate the electronic structure of porous CoP by introducing lattice distortion. Density functional theory (DFT) calculations predict that such synergistic doping can establish an \"adsorption-diffusion-dissociation\" multi-element catalytic pathway during the reaction, where water molecules preferentially adsorb at Co sites and migrate to low-energy-barrier RuCo bridge sites for dissociation, with a water dissociation barrier as low as 0.23 eV. Based on this theoretical design, Ru-F-CoP was prepared in situ on a nickel foam substrate and systematically characterized. Structural analysis shows that Ru substitution for Co introduces positive chemical pressure and local lattice strain, leading to expansion of the unit cell parameters and reconstruction of the electronic environment. F doping further generates localized electric field effects, downshifts the Co d-band center, enhances Lewis acidity, and forms uniformly distributed mesoporous helical nanorod arrays, increasing the specific surface area from 93.9 m<sup>2</sup> g<sup>-1</sup> to 229.3 m<sup>2</sup> g<sup>-1</sup>. Electrochemical testing results validate the design strategy, demonstrating excellent bifunctional catalytic performance in alkaline electrolyte, with HER and OER overpotentials of only 57 mV and 211 mV at 10 mA cm<sup>-2</sup>, and an overall water-splitting voltage of just 1.521 V. This study provides new insights and theoretical guidance for the rational design of high-efficiency non-noble metal electrocatalysts.</p>","PeriodicalId":351,"journal":{"name":"Journal of Colloid and Interface Science","volume":"703 Pt 2","pages":"139268"},"PeriodicalIF":9.7,"publicationDate":"2025-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145342436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hui Kang , Chen-Ning Li , Lifei Yin , Jiabao Gui , Meng Wang , Yang Chen , Jinping Li , Libo Li
{"title":"Inverse selectivity for CO2 over C2H2 in an interdigitated coordination polymer","authors":"Hui Kang , Chen-Ning Li , Lifei Yin , Jiabao Gui , Meng Wang , Yang Chen , Jinping Li , Libo Li","doi":"10.1016/j.jcis.2025.139275","DOIUrl":"10.1016/j.jcis.2025.139275","url":null,"abstract":"<div><div>The separation of carbon dioxide (CO<sub>2</sub>) from acetylene (C<sub>2</sub>H<sub>2</sub>) is crucial but highly challenging due to their similar molecular dimensions and physicochemical properties. In contrast to C<sub>2</sub>H<sub>2</sub>-selective adsorbents, CO<sub>2</sub>-selective adsorption strategy substantially reduces energy consumption by eliminating the need for additional C<sub>2</sub>H<sub>2</sub> desorption steps. However, the development of CO<sub>2</sub>-selective adsorbents capable of reversing C<sub>2</sub>H<sub>2</sub>/CO<sub>2</sub> separation remains limited and requires further exploration. Herein, we report a porous coordination polymer, [Cu(5-NH<sub>2</sub>-ipa)(pia)], featuring an interdigitated structure with one-dimensional corrugated channels to directly purify C<sub>2</sub>H<sub>2</sub>. Adsorption results indicate that at 298 K and 1.0 bar, [Cu(5-NH<sub>2</sub>-ipa)(pia)] exhibits a CO<sub>2</sub>/C<sub>2</sub>H<sub>2</sub> uptake ratio of 2.09 and IAST (Ideal adsorbed solution theory) selectivity of 10.9. It possesses optimally sized pores with an electrostatic potential that is highly complementary to the electrostatic properties of CO<sub>2</sub>, enabling preferential CO<sub>2</sub> adsorption through strong electrostatic interactions and hydrogen bonding. This result is well supported by molecular simulation and theoretical calculations. Furthermore, experimental breakthrough tests demonstrate that high-purity CO<sub>2</sub> can be directly obtained from CO<sub>2</sub> and C<sub>2</sub>H<sub>2</sub> mixtures. This work paves the way for the future development of advanced porous materials and inspires their use for CO<sub>2</sub>-selective capture from C<sub>2</sub>H<sub>2</sub>.</div></div>","PeriodicalId":351,"journal":{"name":"Journal of Colloid and Interface Science","volume":"703 ","pages":"Article 139275"},"PeriodicalIF":9.7,"publicationDate":"2025-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145318069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Dynamic surface reconstruction of pentlandite catalyst for enhanced water oxidation reaction.","authors":"Qiqi Li, Yongqiang Ni, Jinyue Pan, Wenli Xu, Qiulin Xu, Qing Shang, Wei Zhao, Yongting Chen, Qin Zhang","doi":"10.1016/j.jcis.2025.139263","DOIUrl":"https://doi.org/10.1016/j.jcis.2025.139263","url":null,"abstract":"<p><p>The development of oxygen evolution reaction (OER) electrocatalysts with high performance and cost-effectiveness are essential for several energy conversion and storage applications. Herein, we present a promising pentlandite OER electrocatalyst (Fe, Ni)<sub>9</sub>S<sub>8</sub>/Fe-Ni<sub>3</sub>S<sub>2</sub>, thereinto the (Fe, Ni)<sub>9</sub>S<sub>8</sub> readily triggers the dynamic surface reconstruction. In-situ characterizations show that the (Fe, Ni)<sub>9</sub>S<sub>8</sub>/Fe-Ni<sub>3</sub>S<sub>2</sub> self-reconstructed to form FeOOH/NiOOH/Ni<sub>3</sub>S<sub>2</sub> during the OER process. Accordingly, the theoretical calculations demonstrate that charge redistribution reduces NiO covalency at the multiphase interface, effectively tuning charge distribution between Ni and O and optimizing the adsorption energy of the <sup>⁎</sup>O intermediate. As expected, the reconstructed FeOOH/NiOOH/Ni<sub>3</sub>S<sub>2</sub> catalyst exhibits outstanding OER performance, with an overpotential of 246 mV and excellent stability for 100 h at 100 mA cm<sup>-2</sup>. This study elucidates the correlation between the dynamic surface reconstruction and enhanced OER activity in the pentlandite electrocatalyst, thus providing a new material for its practical application in alkaline conditions.</p>","PeriodicalId":351,"journal":{"name":"Journal of Colloid and Interface Science","volume":"703 Pt 2","pages":"139263"},"PeriodicalIF":9.7,"publicationDate":"2025-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145342437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jinpeng Wang , Yuqing Cao , Xiaoyong Wu , Hefa Cheng , Dejin Wang
{"title":"High-efficiency periodate activation by CeO2 under solar light via coordination environment modulation: Synergy between facets and cu species modification","authors":"Jinpeng Wang , Yuqing Cao , Xiaoyong Wu , Hefa Cheng , Dejin Wang","doi":"10.1016/j.jcis.2025.139253","DOIUrl":"10.1016/j.jcis.2025.139253","url":null,"abstract":"<div><div>Cerium oxide (CeO<sub>2</sub>) is a rare earth metal oxide that shows potential for wastewater treatment in sunlight-mediated periodate (PI) activation, although its application of CeO<sub>2</sub> is restricted by limited active sites and light absorption. In this work, facet engineering and heterometallic atom substitution were used to manipulate the coordination environment of CeO<sub>2</sub> to boost its catalytic activity. Cu species-modified CeO<sub>2</sub> with dominant exposed {100}, {110}, and {111} facets were prepared, respectively. The modification of facets by Cu species improved the degradation efficiency of CeO<sub>2</sub> for antibiotic wastewater, and the degradation efficiency was Cu-{110} (99.28 %) > Cu-{100} (95.80 %) > Cu-{111} (89.24 %). In the sunlight-mediated PI activation, Cu-{110} exhibits a wide pH adaptability range for pollutant degradation, excellent anti-inhibition to anions and water matrices, and long-term catalytic stability. The biological toxicity of TC wastewater treated with Cu-{110} was completely removed and deeply purified. Characterization and theoretical calculations revealed that the facet engineering and Cu species modification coupling strategy regulated the coordination environment of the CeO<sub>2</sub> surface, induced the adsorption and complexation of PI in the low-coordinated state ≡Ce(III) atoms adjacent to oxygen defects, and thus accelerated the generation of radicals <sup><strong>•</strong></sup>OH, IO<sub>4</sub><sup><strong>•</strong>−</sup> and non-radical <sup>1</sup>O<sub>2</sub>, as well as the electron transfer process. Besides, the regulation of the coordination environment expanded the absorption range of CeO<sub>2</sub> for sunlight and elevated the separation of photogenerated carriers, achieving continuous regeneration of active sites. This work develops an efficient catalyst for sunlight-mediated PI activation and provides new insights into modulation of the coordination environment of metal oxide catalysts to boost their activity in wastewater purification.</div></div>","PeriodicalId":351,"journal":{"name":"Journal of Colloid and Interface Science","volume":"703 ","pages":"Article 139253"},"PeriodicalIF":9.7,"publicationDate":"2025-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145312037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pami Yang , Yuancheng Liu , Qin Zeng , Shuang Zhao , Yi Zhang , Junhong Yang , Ke Yin , Wuming Wu , Chunyan Deng
{"title":"Near-infrared and pH dual-responsive chitosan/epigallocatechin gallate/hollow CuS hydrogel reprograms ROS dynamics for infected wound healing","authors":"Pami Yang , Yuancheng Liu , Qin Zeng , Shuang Zhao , Yi Zhang , Junhong Yang , Ke Yin , Wuming Wu , Chunyan Deng","doi":"10.1016/j.jcis.2025.139250","DOIUrl":"10.1016/j.jcis.2025.139250","url":null,"abstract":"<div><div>Bacterial-infected wounds pose a clinical challenge requiring innovative strategies integrating precise antibacterial action and microenvironment reprogramming. To address this, a multifunctional H-CuS NPs@epigallocatechin gallate (EGCG)/chitosan (CS)/3-formylphenylboronic acid (3-FPBA) hydrogel (H-CuS@EGCG HY) was engineered. This hydrogel exhibits injectability, self-healing, tissue adhesion, and pH-responsive behavior. During the initial phase of wound infection (weakly acidic microenvironment), this network undergoes controlled dissociation, enabling on-demand localized release of EGCG and Cu<sup>1+/2+</sup>. Under near-infrared (NIR) irradiation, the photothermal effect of H-CuS NPs promotes mild heating, which enhances EGCG/Cu<sup>1+/2+</sup> release and penetration. The released Cu<sup>1+/2+</sup> further catalyzes •OH generation from H<sub>2</sub>O<sub>2</sub> via Fenton reaction, synergizing with EGCG and photothermal therapy to improve antibacterial efficacy. Additionally, EGCG scavenges excess radicals, reducing oxidative stress and inflammation, while Cu<sup>1+/2+</sup> supports angiogenesis via VEGF regulation-collectively reprogramming the wound microenvironment. In vitro tests showed broad-spectrum antimicrobial activity with a 99 % eradication rate. In <em>S. aureus</em>-infected mouse models, compared to the control group, the H-CuS@EGCG HY + NIR group significantly reduced the levels of inflammatory cytokines (TNF-α), promoted the expression of CD31 and CD206, and effectively modulated the wound microenvironment, ultimately resulting in complete wound closure (100 %) by day 13, accompanied by full epidermal regeneration and minimal scarring. This study provides a promising strategy for the treatment of clinical wounds.</div></div>","PeriodicalId":351,"journal":{"name":"Journal of Colloid and Interface Science","volume":"703 ","pages":"Article 139250"},"PeriodicalIF":9.7,"publicationDate":"2025-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145321388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yong Li , Kai Huang , Wenhui Liu , Kang Wang , Shuai Fu , Huazhang Guo , Jiye Zhang , Cheng Lian , Liang Wang
{"title":"Interfacial engineering of carbon quantum dot/metal-organic framework heterostructures for boosted urea electrosynthesis from carbon dioxide and nitrate","authors":"Yong Li , Kai Huang , Wenhui Liu , Kang Wang , Shuai Fu , Huazhang Guo , Jiye Zhang , Cheng Lian , Liang Wang","doi":"10.1016/j.jcis.2025.139264","DOIUrl":"10.1016/j.jcis.2025.139264","url":null,"abstract":"<div><div>Electrocatalytic urea synthesis from CO<sub>2</sub> and NO<sub>3</sub><sup>−</sup> offers a sustainable alternative to conventional energy-intensive industrial processes. However, it remains hindered by sluggish C<img>N coupling kinetics and mismatched CO<sub>2</sub>/NO<sub>3</sub><sup>−</sup> reduction rates. Herein, a carbon quantum dots (CQDs)/metal-organic framework (MOF) heterostructure (Cu-MOF-CQD) was constructed by integrating amino-rich CQDs into the porous Cu-BTC framework (BTC = 1,3,5-benzenetricarboxylic acid) via a one-step ultrasonic-static strategy. The integration of CQDs markedly enhances the electrical conductivity of Cu-MOF and modulates the interfacial electronic structure through interactions between CQDs surface groups and unsaturated Cu sites within Cu-MOF, thereby enriching high-valence Cu species and facilitating charge transfer. Operando spectroscopic characterizations combined with density functional theory calculations unveil that the interface effect of Cu-MOF-CQD provides a stronger driving force for *COOH to *CO conversion and accelerates the coupling of *CO and *NH<sub>2</sub> intermediates, thus promoting efficient C<img>N bond formation. Benefiting from this synergistic interface, in a flow cell, Cu-MOF-CQD achieves a maximum urea Faradaic efficiency of 18.5 ± 0.7 % at −0.5 V vs. RHE and the corresponding urea yield rate of 260.2 ± 10.1 μg h<sup>−1</sup> mg<sub>cat</sub><sup>−1</sup>, surpassing the performance of pristine Cu-MOF. This work establishes a generalizable strategy of zero-dimensional carbon/MOF heterostructures for boosting C<img>N coupling performance, offering new design principles for next-generation electrocatalysts in sustainable C<img>N coupling reactions.</div></div>","PeriodicalId":351,"journal":{"name":"Journal of Colloid and Interface Science","volume":"703 ","pages":"Article 139264"},"PeriodicalIF":9.7,"publicationDate":"2025-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145318079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Li Liu , Buyuan Tan , Xiaohui Yang , Rong Wang , Yi Wang , Wensheng Fu
{"title":"Electron trapping agent triggers high valence active sites driving electrochemical urea-assisted hydrogen production","authors":"Li Liu , Buyuan Tan , Xiaohui Yang , Rong Wang , Yi Wang , Wensheng Fu","doi":"10.1016/j.jcis.2025.139231","DOIUrl":"10.1016/j.jcis.2025.139231","url":null,"abstract":"<div><div>Urea oxidation reaction (UOR) is an ideal alternative to the traditional oxygen evolution reaction for hydrogen production in energy-saving water electrolysers. Ni<sup>3+</sup> has been considered as the most active site in the UOR. However, due to the high oxidation energy barrier and strong oxidizability, it is difficult to obtain sufficient Ni<sup>3+</sup> efficiently and steadily. Regarding this issue, we have synthesized a self-supporting electrode of V-doped Ni, Fe-based layered double hydroxides on a nickel foam substrate (V-NiFe-LDHs@NF), where the high-valence Ni<sup>3+</sup> active species are formed and stabilized from the V-induced lattice distortion and electronic rearrangement. V-NiFe-LDHs@NF exhibits excellent UOR catalytic performances with only 1.253/1.372 V vs. RHE at the current density of 10/100 mA cm<sup>−2</sup>, respectively. Structure-activity relationship studies demonstrate that the V as electron trapping agents can change the bond relationship between the key intermediate *CONH<sub>2</sub>N and the active site by regulating the electron cloud density of the active center, thus avoiding the inactivation of the high valence active species due to migration, covering or reduction in complex environments. When it is directly used in urea-assisted hydrogen production, the cell voltage is only 1.432 V at 100 mA cm<sup>−2</sup>, lower 308 mV than that of the traditional water electrolysis.</div></div>","PeriodicalId":351,"journal":{"name":"Journal of Colloid and Interface Science","volume":"703 ","pages":"Article 139231"},"PeriodicalIF":9.7,"publicationDate":"2025-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145311956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}