针刺研究最新文献

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[Application of transcutaneous electrical acupoint stimulation in preoperative analgesia for intertrochanteric fracture of femur in elderly patients]. [经皮穴位电刺激在老年股骨粗隆间骨折术前镇痛中的应用]。
针刺研究 Pub Date : 2025-06-25 DOI: 10.13702/j.1000-0607.20241048
Xin Zhou, Ming-Li Huang, Jin-Wei Zhao, Xiao-Ling Rong, Zhi-Yuan Han, Xiao-Tao Chen, Hong-Jiang Jiang, Chang-Jun Ju
{"title":"[Application of transcutaneous electrical acupoint stimulation in preoperative analgesia for intertrochanteric fracture of femur in elderly patients].","authors":"Xin Zhou, Ming-Li Huang, Jin-Wei Zhao, Xiao-Ling Rong, Zhi-Yuan Han, Xiao-Tao Chen, Hong-Jiang Jiang, Chang-Jun Ju","doi":"10.13702/j.1000-0607.20241048","DOIUrl":"10.13702/j.1000-0607.20241048","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate the clinical effect of transcutaneous electrical acupoint stimulation(TEAS) on preoperative analgesia for the elderly patients with intertrochanteric fracture of femur.</p><p><strong>Methods: </strong>A total of 126 elderly patients with intertrochanteric fracture of femur were randomized into an observation group(63 cases, one case dropped out) and a control group(63 cases, 2 cases dropped out ). In the observation group, TEAS was operated at Huantiao (GB30), Yanglingquan (GB34), Zusanli (ST36) and Kuanguxue (Extra) on the affected side. In the control group, the sham-TEAS was delivered with the electrode patches attached on the same points, without electric current exerted. The interventions of the two groups started in 1 h on the 1st day of hospital-stay, stimulated for 1 h, twice daily, for maximal 3 d. The numeric rating scale (NRS) was observed on the day of hospital administration (T0), at 1 h (T1), 12 h (T2), 24 h (T3) and 48 h (T4) after the 1<sup>st</sup> intervention of the two groups, separately. The amount of additional analgesic drugs, the incidence of complications, and patient satisfaction for analgesia were recorded.</p><p><strong>Results: </strong>The NRS scores either resting or passive movement from T1 to T4 were reduced compared with the score at T0 in the two groups (<i>P</i><0.05). Compared with the control group, the NRS scores of observation group were lower from T1 to T4 when resting and from T2 to T4 during passive movement (<i>P</i><0.05). The analgesia satisfaction score of the observation group was higher than that of the control group (<i>P</i><0.05). The incidence of nausea and vomiting was lower in the observation group compared with the control group (<i>P</i><0.05). The amount of additional analgesic drugs was reduced in the observation group in comparison with the control group (<i>P<</i>0.05).</p><p><strong>Conclusions: </strong>TEAS exhibits the favorable preoperative analgesic effects in the elderly patients with intertrochanteric fracture of femur, and it reduces the dosage of analgesic drugs, and the occurrence of complications.</p>","PeriodicalId":34919,"journal":{"name":"针刺研究","volume":"50 6","pages":"689-693"},"PeriodicalIF":0.0,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144477102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Analysis on acupoint compatibility regularity and application characteristics of moxibustion in the treatment of cognitive disorders]. [穴位配伍规律及艾灸治疗认知障碍的应用特点分析]。
针刺研究 Pub Date : 2025-06-25 DOI: 10.13702/j.1000-0607.20241054
Xiao-Xia Chen, Lu-Jun Tang, Di Ren, Li-Hua Zhao
{"title":"[Analysis on acupoint compatibility regularity and application characteristics of moxibustion in the treatment of cognitive disorders].","authors":"Xiao-Xia Chen, Lu-Jun Tang, Di Ren, Li-Hua Zhao","doi":"10.13702/j.1000-0607.20241054","DOIUrl":"https://doi.org/10.13702/j.1000-0607.20241054","url":null,"abstract":"<p><strong>Objectives: </strong>To summarize the acupoint compatibility regularity and application characteristics of moxibustion in the treatment of cognitive impairment disorders through data mining technology.</p><p><strong>Methods: </strong>Eligible clinical studies of moxibustion for treatment of cognitive disorders were searched from databases of PubMed, Embase, Cochrane Library, Web of Science, CNKI, Wanfang, VIP, and SinoMed from the inception of the databases to August 3<sup>rd</sup>, 2024 and according to our inclusion and exclusion criteria. Then, a new database for moxibustion treatment of cognitive impairment disorders was established to conduct the standardized processing and frequency analysis using Microsoft Excel 2019. The association rule analysis was performed using the Apriori algorithm of IBM SPSS Modeler 18.0 software. A complex network diagram of high-frequency co-occurring acupoints (stronger compatibility connection between acupoints) was drawn using Cytoscape 3.10.2 software, and the cluster analysis was performed using Origin Lab version 2021 software.</p><p><strong>Results: </strong>A total of 121 articles were included, containing 139 prescriptions and 66 acupoints, with a total frequency of acupoints being 633. The top six acupoints in order are Baihui(GV20), Zusanli (ST36), Shenting (GV24), Dazhui(GV14), Sanyinjiao(SP6) and Shenshu (BL23), and the main meridian selected is the Governer Vessel. The frequently used acupoints mostly distributed in head, face and the lower limbs. Among the specific acupoints, the intersection acupoints are the most frequently used. Among the association rules, GV20-GV24 and ST36-SP6 had the highest support degree. Cluster analysis showed that the acupoints can be divided into 4 groups. The simple moxibustion method is mostly used, and the mild moxibustion is the first one. The mostly used number of moxa-cones is 3, moxibustion duration is 30 min each time, a single course of treatment is 6 times a week, and the total course of treatment is 8 weeks.</p><p><strong>Conclusions: </strong>In the treatment of cognitive impairment disorders, the main acupoints frequently employed are GV20, GV24, GV14, ST36, SP6 and BL23. With an appropriate moxibustion dosage, a good clinical effect can be achieved.</p>","PeriodicalId":34919,"journal":{"name":"针刺研究","volume":"50 6","pages":"694-702"},"PeriodicalIF":0.0,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144477101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Effect of electroacupuncture on expression in blood-brain barrier in rats with cerebral ischemia-reperfusion injury by regulating HIF-1α/VEGF/MMP-9 signaling pathway]. [电针通过调节HIF-1α/VEGF/MMP-9信号通路对脑缺血再灌注损伤大鼠血脑屏障表达的影响]。
针刺研究 Pub Date : 2025-06-25 DOI: 10.13702/j.1000-0607.20241047
Teng-Wei Liao, Ying-Yan Wang, Shao-Wen Li, Xiao-Wen Xu, Yan-Zhen Zhu, Yu-Ting Tang, Lin Liu, Rui-Huan Pan, Hong-Xia Chen, Le-Chang Zhan
{"title":"[Effect of electroacupuncture on expression in blood-brain barrier in rats with cerebral ischemia-reperfusion injury by regulating HIF-1α/VEGF/MMP-9 signaling pathway].","authors":"Teng-Wei Liao, Ying-Yan Wang, Shao-Wen Li, Xiao-Wen Xu, Yan-Zhen Zhu, Yu-Ting Tang, Lin Liu, Rui-Huan Pan, Hong-Xia Chen, Le-Chang Zhan","doi":"10.13702/j.1000-0607.20241047","DOIUrl":"https://doi.org/10.13702/j.1000-0607.20241047","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objectives: &lt;/strong&gt;To observe the effect of electroacupuncture (EA) on the expression of hypoxia-inducible factor 1α (HIF-1α), vascular endothelial growth factor (VEGF), matrix metalloproteinases 9 (MMP-9) and tight junction proteins in rats with cerebral ischemia-reperfusion injury (CI/RI) , so as to explore its potential mechanism in alleviating injury of neurological function and blood-brain barrier (BBB).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;A total of 84 male SD rats were used in the present study. The CIRI model was established by occlusion of the middle cerebral artery and reperfusion (MCAO/R), followed by dividing the CIRI rats into model group, EA group, and edaravone group (&lt;i&gt;n&lt;/i&gt;=21 in each group). And another 21 normal rats were used as the sham operation group. For rats of the EA group, EA (2 Hz/15 Hz, 1 mA) was applied to \"Baihui\" (GV20) and \"Zusanli\" (ST36) on the affected limb for 20 min, once a day for 3 days. Rats of the edaravone group were intraperitoneally injected with edaravone injection (3 mg/kg), once a day for 3 days. The modified neurological severity score (mNSS) was used to evaluate the neurological behavior of rats. TTC staining was used to detect the percentage of cerebral infarction volume. HE staining was used to observe the pathological changes of cerebral cortex in ischemic area. Transmission electron microscopy was used to observe the changes of BBB ultrastructure in ischemic cortex. Evans blue (EB) staining was used to evaluate BBB permeability. Immunofluorescence was used to detect the expression of HIF-1α and VEGF protein in ischemic cortex. The protein and mRNA expressions of HIF-1α, VEGF, MMP-9, Zonula Occludens 1 (ZO-1), Occludin and Claudin-5 in the ischemic cortex were detected by Western blot or real-time PCR, respectively.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Compared with the sham operation group, the neurological deficit score, the percentage of cerebral infarction volume, EB leakage, the positive expressions of HIF-1α and VEGF, the protein and mRNA expressions of HIF-1α, VEGF and MMP-9 of ischemic cortex were increased (&lt;i&gt;P&lt;/i&gt;&lt;0.01) in the model group , while the protein and mRNA expressions of ZO-1, Occludin and Claudin-5 were decreased (&lt;i&gt;P&lt;/i&gt;&lt;0.01). After the intervention and compared with the model group, the neurological deficit score, the percentage of cerebral infarction volume, EB leakage, the positive expressions of HIF-1α and VEGF, the protein and mRNA expressions of HIF-1α, VEGF and MMP-9 of ischemic cortex were decreased (&lt;i&gt;P&lt;/i&gt;&lt;0.01, &lt;i&gt;P&lt;/i&gt;&lt;0.05) in the EA and edaravone groups;the protein and mRNA expression of ZO-1, Occludin and Claudin-5 were increased (&lt;i&gt;P&lt;/i&gt;&lt;0.05, &lt;i&gt;P&lt;/i&gt;&lt;0.01) in the EA group;the protein and mRNA expression of Occludin were increased (&lt;i&gt;P&lt;/i&gt;&lt;0.01, &lt;i&gt;P&lt;/i&gt;&lt;0.05) and the mRNA expression of ZO-1 and Claudin-5 were increased (&lt;i&gt;P&lt;/i&gt;&lt;0.05, &lt;i&gt;P&lt;/i&gt;&lt;0.01) in the edaravone group. The ultrastructure of BBB was damaged in the model group, which were re","PeriodicalId":34919,"journal":{"name":"针刺研究","volume":"50 6","pages":"613-623"},"PeriodicalIF":0.0,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144477106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Research progress on the effect of α-synuclein in acupuncture treatment for Parkinson's disease]. [α-突触核蛋白针刺治疗帕金森病的研究进展]。
针刺研究 Pub Date : 2025-06-25 DOI: 10.13702/j.1000-0607.20240237
Yi-Wei Shen, Shun Wang, Yan Bai, Yu-Lin Wang, Cong He, Yu Zhang, Zheng-Nan Liu
{"title":"[Research progress on the effect of α-synuclein in acupuncture treatment for Parkinson's disease].","authors":"Yi-Wei Shen, Shun Wang, Yan Bai, Yu-Lin Wang, Cong He, Yu Zhang, Zheng-Nan Liu","doi":"10.13702/j.1000-0607.20240237","DOIUrl":"10.13702/j.1000-0607.20240237","url":null,"abstract":"<p><p>Parkinson's disease (PD) is a chronic progressive neurological degenerative disease caused by the degeneration of dopaminergic neurons in the substantia nigra. α-synuclein (α-Syn) misfolding and aggregation is the crucial pathogenesis of PD, and is closely related to the other pathogenesis, such as brain-gut axis dysfunction, mitochondrial dysfunction, oxidative stress, neuroinflammation, iron and lipid metabolic disorders, and autophagy lysosomal dysfunction. Acupuncture plays a neuroprotective role by attenuating neuroinflammation, regulating brain-gut axis, repairing ubiquitin-proteasome system and autophagy lysosomal system, and modulating signaling pathways, so as to inhibit α-Syn abnormal folding and aggregation. This article reviews the effect of α-Syn in the pathogenesis of PD and acupuncture treatment, so as to provide the valuable guidance for clinical treatment.</p>","PeriodicalId":34919,"journal":{"name":"针刺研究","volume":"50 6","pages":"714-720"},"PeriodicalIF":0.0,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144477122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Advances of researches on acupuncture treatment of Parkinson's disease by regulating mitochondrial function]. [针刺调节线粒体功能治疗帕金森病研究进展]。
针刺研究 Pub Date : 2025-06-25 DOI: 10.13702/j.1000-0607.20240406
Ru-Qi Zhang, Bing-Xu Zhu, Xiao-Jie Dong, Lin Chen, Sheng-Chun Wang
{"title":"[Advances of researches on acupuncture treatment of Parkinson's disease by regulating mitochondrial function].","authors":"Ru-Qi Zhang, Bing-Xu Zhu, Xiao-Jie Dong, Lin Chen, Sheng-Chun Wang","doi":"10.13702/j.1000-0607.20240406","DOIUrl":"https://doi.org/10.13702/j.1000-0607.20240406","url":null,"abstract":"<p><p>The pathological mechanism of Parkinson's disease (PD) is complex and affected by multi-system and multi-level factors including mitochondrial dysfunction (MD). It has been demonstrated that all patients with PD have a marked loss of dopaminergic neurons in the substantial nigra pars compacta, and MD is an important initial factor causing dopaminergic neuron degeneration. Clinical practice has shown that acupuncture has a positive role in the treatment of PD. In the present article, we summed up recent research results about the mechanisms of acupuncture underlying improvement of PD from the standpoint of mitochondrial function. Acupuncture has been shown to be able in improving mitochondrial function, and restoring mitochondrial homeostasis, and protecting the normal morphological structure of mitochondria. It can also regulate the expression of peroxisome proliferator-activated receptor-gamma coactivator-1alpha (PGC-1α), adenosine 5'-monophosphate (AMP)-activated protein kinase (AMPK), and Sirtuins (SIRT) to take part in mitochondrial biogenesis; decrease the levels of dynamin-related protein 1 (Drp1), mitochondrial fission factor (MFF), and mitochondrial fission protein 1 (Fis1) protein to preserve mitochondrial dynamic stability; and modulate the expression of PTEN-induced putative kinase 1 (PINK1), Parkin, P62, microtubule-associated protein light chain 3Ⅱ (LC3Ⅱ), and Beclin1 to promote autophagy. In addition, through controlling mitochondrial energy metabolism, preserving calcium homeostasis, reducing oxidative stress, and preventing neuronal apoptosis, acupuncture can also help improve mitochondrial dysfunction and prevent the onset and progression of PD. However, more researches are warranted to fully unravel the underlying mechanisms of acupuncture intervention before it can be popularized in clinical settings.</p>","PeriodicalId":34919,"journal":{"name":"针刺研究","volume":"50 6","pages":"721-727"},"PeriodicalIF":0.0,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144477100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Clinical observation of electroacupuncture at Erheliao (TE22) and Jianer (Extra) in treatment of subjective tinnitus in the acute phase]. [电针二合髎穴(TE22)、夹耳穴(Extra)治疗急性期主观性耳鸣的临床观察]。
针刺研究 Pub Date : 2025-05-25 DOI: 10.13702/j.1000-0607.20240191
Li-Wei Xu, Yu-Lan Liu, Yue Wang, Xing-Miao Quan, Ying Li, Yan-Hong Hao, Hong-Ling Bao
{"title":"[Clinical observation of electroacupuncture at Erheliao (TE22) and Jianer (Extra) in treatment of subjective tinnitus in the acute phase].","authors":"Li-Wei Xu, Yu-Lan Liu, Yue Wang, Xing-Miao Quan, Ying Li, Yan-Hong Hao, Hong-Ling Bao","doi":"10.13702/j.1000-0607.20240191","DOIUrl":"10.13702/j.1000-0607.20240191","url":null,"abstract":"<p><strong>Objectives: </strong>To analyze the clinical effect of electroacupuncture (EA) at Erheliao (TE22) and Jianer (Extra) on subjective tinnitus in the acute phase.</p><p><strong>Methods: </strong>A total of 68 patients with subjective tinnitus were randomly divided into an observation group (34 cases, 1 case dropped out) and a control group (34 cases, 1 case dropped out). In the control group, the routine acupuncture was administrated. In the observation group, besides the regimen as the control group, EA was applied to TE22 and Jianer (Extra). In the two groups, the needles were retained for 30 min in each intervention, and the intervention was delivered once daily and 1 course of treatment was composed of 15 days;and two courses of treatment were required. Before and after intervention completion, the scores of tinnitus evaluation questionnaire (TEQ), visual analogue scale (VAS) for tinnitus and insomnia severity index (ISI) were observed. Using SF-36 quality of life assessment scale, the scores for physical health and mental health were evaluated. The clinical effect was calculated.</p><p><strong>Results: </strong>After treatment, the scores of TEQ, VAS and ISI were decreased in the two groups compared with those before treatment (<i>P<</i>0.05). The scores of TEQ, VAS and ISI in the observation group were lower than those in the control group (<i>P<</i>0.05). When compared with the scores before treatment, the scores of physical health and mental health were increased after treatment in both groups (<i>P<</i>0.05), and there was no significant difference in the score of physical health between the two groups, but the score of mental health in the observation group was higher than that in the control group (<i>P<</i>0.05). The total effective rate was 87.9% (29/33) in the observation group and 72.7% (24/33) in the control group. The total effective rate in the observation group was superior to that of the control group (<i>P<</i>0.05).</p><p><strong>Conclusions: </strong>EA at TE22 and Jianer (Extra) combined with routine acupuncure can better promote the recovery of tinnitus and improve the quality of lift and psychological health in the patients, presenting a satisfactory clinical effect.</p>","PeriodicalId":34919,"journal":{"name":"针刺研究","volume":"50 5","pages":"599-604"},"PeriodicalIF":0.0,"publicationDate":"2025-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144102559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Effect of auricular acupuncture combined with intermittent catheterization on urethral sphincter overactivity in the patients with neurogenic bladder after spinal cord injury]. [耳针联合间歇导尿对脊髓损伤后神经源性膀胱患者尿道括约肌过度活动的影响]。
针刺研究 Pub Date : 2025-05-25 DOI: 10.13702/j.1000-0607.20240245
Zhi-Lan Zhang, Ya-Feng Ren, Xiao-Meng Huang, Hui-Lin Wei, Wen-Ya Shang, Jing Huang, Bing Li
{"title":"[Effect of auricular acupuncture combined with intermittent catheterization on urethral sphincter overactivity in the patients with neurogenic bladder after spinal cord injury].","authors":"Zhi-Lan Zhang, Ya-Feng Ren, Xiao-Meng Huang, Hui-Lin Wei, Wen-Ya Shang, Jing Huang, Bing Li","doi":"10.13702/j.1000-0607.20240245","DOIUrl":"10.13702/j.1000-0607.20240245","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objectives: &lt;/strong&gt;To observe the clinical efficacy of auricular acupuncture combined with intermittent catheterization on urethral sphincter overactivity in patients with neurogenic bladder (NB) after spinal cord injury (SCI).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;A total of 90 patients with SCI were randomly divided into an auricular acupuncture group, an intermittent catheterization group and a combined treatment group, 30 cases in each group. All the patients in the three groups received the basic rehabilitation nursing and normal rehabilitation training. Additionally, in the auricular acupuncture group, auricular acupuncture was applied to \"Spleen\" (CO13), \"Kidney\" (CO10), \"Bladder\" (CO9) and \"Subcortex\" (AT4). In the intermittent catheterization group, the intermittent catheterization was operated. In the combined treatment group, the auricular acupuncture and the intermittent catheterization were delivered in combination. In the auricular acupuncture and the combined treatment group, the needles were retained for 1 h, once daily. One course of treatment was composed of 6 d and 4 courses were required. At the baseline and after interventions, the maximum urethral pressure (MUP), the residual urine volume (RU), the case number of urethral sphincter opening, the case number of vesicoureteral reflux, the number of white blood cells in urine, the case number of bladder function balance and traditional Chinese medicine (TCM) syndrome score were compared, with clinical efficacy evaluated.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Compared with the baseline, MUP, RU, the case number of urethral sphincter opening, the case number of vesicoureteral reflux, the number of white blood cells in urine, the case number of bladder function balance, and TCM symptom score were improved in the combined treatment group after 4 weeks of treatment (&lt;i&gt;P&lt;/i&gt;&lt;0.05);and the therapeutic effects of the above indicators except the number of white blood cells in urine and TCM symptom score were improved more significantly when compared with the auricular acupuncture group and the intermittent catheterization group (&lt;i&gt;P&lt;/i&gt;&lt;0.05). In the auricular acupuncture group, MUP, RU, the case number of urethral sphincter opening, the case number of vesicoureteral reflux, the case number of bladder function balance and TCM symptom score were ameliorated in comparison with the baseline (&lt;i&gt;P&lt;/i&gt;&lt;0.05);while in the intermittent catheterization group, the improvements were obtained in the RU, the case number of urethral sphincter opening, the case number of vesicoureteral reflux, the case number of bladder function balance and the number of white blood cells in urine (&lt;i&gt;P&lt;/i&gt;&lt;0.05). The total effective rate in combined treatment group was significantly higher than that in auricular acupuncture group and intermittent catheterization group (&lt;i&gt;P&lt;/i&gt;&lt;0.05).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;The combination of auricular acupuncture and intermittent catheterization is clearly effective ","PeriodicalId":34919,"journal":{"name":"针刺研究","volume":"50 5","pages":"584-591"},"PeriodicalIF":0.0,"publicationDate":"2025-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144102628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Acupuncture effects and neuro-immune regulation: a breakthrough in "treating diseases at the root"]. 【针刺效应与神经免疫调节:“治本”的突破】。
针刺研究 Pub Date : 2025-05-25 DOI: 10.13702/j.1000-0607.20250346
Jia-He Tian, Hong-Ye Wan, Shen-Bin Liu
{"title":"[Acupuncture effects and neuro-immune regulation: a breakthrough in \"treating diseases at the root\"].","authors":"Jia-He Tian, Hong-Ye Wan, Shen-Bin Liu","doi":"10.13702/j.1000-0607.20250346","DOIUrl":"10.13702/j.1000-0607.20250346","url":null,"abstract":"<p><p>The holistic philosophy of traditional Chinese medicine (TCM) embodied in acupuncture therapy has gained novel insights within the neuroimmune regulatory framework. Its mechanistic framework encompasses 3 pivotal dimensions: 1) Acupuncture stimulation at acupoints transduces mechanical signals into neuroelectrical and biochemical signals, initiating localized immunomodulatory microenvironment remodeling; 2) The autonomic nervous system orchestrates systemic and organ-specific immune homeostasis through vagus nerve-mediated anti-inflammatory effects and sympathetic nerve-mediated bidirectional regulatory dynamics; 3) The enteric nervous system facilitates barrier restoration via neuropeptide-microbiota crosstalk, establishing bidirectional gut-brain axis immune communication. Emerging bioelectronic devices based on somatosensory-autonomic reflex circuits are driving the evolution of acupuncture from empirical practice to precision neuromodulation. Future research should integrate multi-omics profiling and artificial intelligence algorithms to construct a comprehensive \"mechanical stimulation-neural coding-immune response\" mapping paradigm. This will operationalize TCM's core principle of \"treating the root of disease\" into targeted neuromodulation strategies against inflammatory and immune-related disorders through defined neural circuit interventions.</p>","PeriodicalId":34919,"journal":{"name":"针刺研究","volume":"50 5","pages":"538-552"},"PeriodicalIF":0.0,"publicationDate":"2025-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144102454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[New technologies serve as accelerators for breakthroughs in modern acupuncture research]. 【新技术是现代针灸研究突破的加速器】
针刺研究 Pub Date : 2025-05-25 DOI: 10.13702/j.1000-0607.20250380
Hai-Fa Qiao
{"title":"[New technologies serve as accelerators for breakthroughs in modern acupuncture research].","authors":"Hai-Fa Qiao","doi":"10.13702/j.1000-0607.20250380","DOIUrl":"10.13702/j.1000-0607.20250380","url":null,"abstract":"<p><p>As one of China's most internationally influential original disciplines, acupuncture-moxibustion has a development history of over 2 000 years. The formation of its early theoretical framework was shaped by contemporaneous technological advancements. This article provided a systematic review of the history of modern acupuncture research, highlighting how early electrophysiological and biochemical techniques validated the objective effects of acupuncture-moxibustion, and, since the 1950s, how studies have elucidated acupuncture's analgesic mechanisms, meridian phenomena, acupoint-visceral organ correlations, and patterns of acupoint efficacy. It emphasized the role of contemporaneous technologies-ranging from systemic, organic approaches down to cellular, molecular, and genetic methods in advancing modern acupuncture-moxibustion research. The article also prospected that the application of emerging technologies such as single-cell sequencing, spatial transcriptomics, neuroimaging, artificial intelligence, and interdisciplinary medicine-engineering integration would play an important role in future acupuncture-moxibustion studies, and stresseed that technology should be applied in a scientifically driven, problem-oriented manner rather than through mere technical accumulation.</p>","PeriodicalId":34919,"journal":{"name":"针刺研究","volume":"50 5","pages":"526-530"},"PeriodicalIF":0.0,"publicationDate":"2025-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144102688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Effects of electroacupuncture at Juliao (GB29) on the gluteus medius and lower limb motor function in patients with stroke-related hemiplegia]. [电针朱利奥穴(GB29)对脑卒中相关性偏瘫患者臀中肌及下肢运动功能的影响]。
针刺研究 Pub Date : 2025-05-25 DOI: 10.13702/j.1000-0607.20240180
Wei-Kun Wu, Dong-Lan Yang, Zi-Han Lin, Jia-Ming Chen, Li-Ping Huang, Wen-Qiang Zhou
{"title":"[Effects of electroacupuncture at Juliao (GB29) on the gluteus medius and lower limb motor function in patients with stroke-related hemiplegia].","authors":"Wei-Kun Wu, Dong-Lan Yang, Zi-Han Lin, Jia-Ming Chen, Li-Ping Huang, Wen-Qiang Zhou","doi":"10.13702/j.1000-0607.20240180","DOIUrl":"10.13702/j.1000-0607.20240180","url":null,"abstract":"<p><strong>Objectives: </strong>To investigate the effects of electroacupuncture (EA) at Juliao (GB29) on lower limb motor function, balance function, and the gluteus medius contraction ratio and thickness in patients with stroke-related hemiplegia, as well as the correlation between the gluteus medius and lower limb motor function and balance function in these patients.</p><p><strong>Methods: </strong>A total of 68 patients with stroke-related hemiplegia were randomly divided into an observation group (34 cases, with 1 dropped out and 1 withdrawal) and a control group (34 cases, with 2 dropped out). The control group received conventional acupuncture in addition to standard medical treatment for their underlying conditions, along with rehabilitation training. The observation group received EA at GB29 on the hemiplegic side for 30 min per session, once daily, 5 times a week, over a total treatment duration of 4 weeks, based on the control group's treatment. Before treatment, the correlation between the contraction ratio of the gluteus medius and the scores of the lower limb Fugl-Meyer Assessment (FMA) and the Berg Balance Scale (BBS) was analyzed. The thickness of the gluteus medius was measured, and the contraction ratio was calculated before treatment and 4 weeks after treatment. Assessments of the lower limb FMA and BBS scores were conducted before treatment, and 2 and 4 weeks after treatment.</p><p><strong>Results: </strong>Before treatment, the contraction ratio and thickness of the gluteus medius on the hemiplegic side were lower than those on the non-hemiplegic side in both groups (<i>P</i><0.05). The gluteus medius contraction ratio before treatment demonstrated a positive correlation with the lower limb FMA and BBS scores (<i>P</i><0.05). The gluteus medius contraction ratio and thickness on the hemiplegic side 4 weeks after treatment, as well as the lower limb FMA and BBS scores 2 and 4 weeks after treatment, were significantly higher than those before treatment in both groups (<i>P</i><0.05). Furthermore, the observation group showed a greater contraction ratio of the gluteus medius, as well as higher FMA and BBS scores 4 weeks after treatment when compared with the control group (<i>P</i><0.05).</p><p><strong>Conclusions: </strong>The level of gluteus medius activation is positively correlated with lower limb motor function and balance function in patients with stroke-related hemiplegia. EA at the GB29 effectively activates the gluteus medius on the hemiplegic side, providing a stability mechanism for the lumbopelvic-hip complex, thereby improving lower limb motor function and balance in patients with stroke.</p>","PeriodicalId":34919,"journal":{"name":"针刺研究","volume":"50 5","pages":"592-598"},"PeriodicalIF":0.0,"publicationDate":"2025-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144102619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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