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Subcutaneous fat necrosis (SCFN) secondary to therapeutic hypothermia with persistent leucocytosis in a neonate 新生儿皮下脂肪坏死(SCFN)继发于治疗性低温伴持续性白细胞增多症
International Journal of Computing and Corporate Research Pub Date : 2021-01-08 DOI: 10.31579/2690-4861/087
Sandhya Govindarajan
{"title":"Subcutaneous fat necrosis (SCFN) secondary to therapeutic hypothermia with persistent leucocytosis in a neonate","authors":"Sandhya Govindarajan","doi":"10.31579/2690-4861/087","DOIUrl":"https://doi.org/10.31579/2690-4861/087","url":null,"abstract":"We report a term male neonate, born to consanguineous parents through a difficult labour who needed resuscitation at birth, followed by ventilation for respiratory distress. In view of suspected Hypoxic Ischemic Injury, he was started on whole body cooling for 72 hours. He was treated as suspected sepsis with 5 days of intravenous antibiotics. On day 6, he was noted to have hard, painless skin nodules of his back and left arm which was clinically diagnosed as subcutaneous fat necrosis. His serum calcium and phosphate levels remained normal throughout hospital stay. His full blood counts and bone profile were monitored regularly. During follow-up at 6 weeks, his white cell counts continued to be high with 69% lymphocytes. To our knowledge, this is the first case of SCFN of a neonate associated with persistent leucocytosis. Haematological and metabolic complications should be closely monitored in a neonate with subcutaneous fat necrosis.","PeriodicalId":347161,"journal":{"name":"International Journal of Computing and Corporate Research","volume":"82 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126282015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acute Kidney Injury in a Case of Multiorgan Failure, Disseminated Intravascular Coagulation and Purpura Fulminans 多器官衰竭、弥散性血管内凝血和暴发性紫癜的急性肾损伤1例
International Journal of Computing and Corporate Research Pub Date : 2021-01-08 DOI: 10.31579/2690-4861/088
Gurwant Kaur
{"title":"Acute Kidney Injury in a Case of Multiorgan Failure, Disseminated Intravascular Coagulation and Purpura Fulminans","authors":"Gurwant Kaur","doi":"10.31579/2690-4861/088","DOIUrl":"https://doi.org/10.31579/2690-4861/088","url":null,"abstract":"Introduction: Purpura fulminans (PF) is a life-threatening syndrome consisting of Disseminated Intravascular Coagulation (DIC), thrombotic occlusion of smalland medium-sized blood vessels with skin necrosis. Although there are few studies in the literature, only a minority of them discuss renal manifestations. Case Report: We present a case of a 57-year-old Caucasian female with acute kidney injury (AKI) in the setting of multiorgan failure (MOF), DIC and PF. She presented with fever, exudative drainage from her port site, and skin changes concerning for bacteremia. Empiric antibiotics were started after blood, urine, and wound cultures were obtained. None of the cultures grew any organisms. Fever resolved after port removal. She exhibited thrombocytopenia, leukopenia, and neutropenia. Urinalysis showed hyaline casts and a fractional excretion of urea (FeUrea) ≤35% indicating a pre-renal state. Her hospital course was complicated by atrial fibrillation, acute hypoxic respiratory failure requiring mechanical ventilation, and hypovolemic shock requiring pressor support. Further, complicated by multiorgan failure including nonoliguric AKI and heart failure with reduced ejection fraction (HFrEF) of ≤65%. Acute skin findings included dusky, purple macules and patches involving all digits of both hands as well as gangrenous changes on the face and toes. It prompted further investigation by Hematology and Dermatology. Skin biopsy showed early leukocytoclastic vasculitis changes. Her laboratory markers were suggestive of DIC and Purpura Fulminans.","PeriodicalId":347161,"journal":{"name":"International Journal of Computing and Corporate Research","volume":"149 4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125882608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of biochemical parameters and hematological profile in the chronic renal failure of pre and post dialysis at Martyr Mohammed El-Najjar Hospital in Rafah, Gaza Strip, Palestine 巴勒斯坦加沙地带拉法穆罕默德·纳贾尔烈士医院透析前后慢性肾衰竭的生化参数和血液学特征评估
International Journal of Computing and Corporate Research Pub Date : 2021-01-04 DOI: 10.31579/2690-4861/097
A. Mustafa
{"title":"Assessment of biochemical parameters and hematological profile in the chronic renal failure of pre and post dialysis at Martyr Mohammed El-Najjar Hospital in Rafah, Gaza Strip, Palestine","authors":"A. Mustafa","doi":"10.31579/2690-4861/097","DOIUrl":"https://doi.org/10.31579/2690-4861/097","url":null,"abstract":"Background: There are limited data on the assessment biochemical and hematological profile in the chronic renal failure of pre and post dialysis in the Gaza Strip. Objective: To evaluating some biochemical parameters and hematological profile in the chronic renal failure of pre and post dialysis at Martyr Mohammed El-Najjar Hospital in Rafah, Gaza Strip, Palestine. Methods: Forty-three (end-stage renal disease) ESRD patients, aged 20-70 years old who were referred to Martyr Mohammed Youssef Al-Najjar Hospital in Rafah for the dialysis department. 43 apparently healthy individuals matched for ages were used as a control group for comparisons. Results: The results showed that post-dialysis higher statistically significant in Hb, RBC, HCT, PLT, AST, ALT, ALP and Ca level than pre-dialysis. While Ph, WBC, RDW, creatinine, Urea was lower statistically significant in post-dialysis than pre-dialysis (P < 0.05). Conclusion: chronic kidney disease shows abnormal hematological parameters, precisely reduced levels of RBC count, hemoglobin, hematocrit, and platelet count, in addition, pre-dialysis patients are more anemic and thrombocytopenic than post-dialysis patients and this is may indicate of lack of blood pressure and diabetic control in these patients. AST& ALT activities vary in concentration before and after dialysis and make the post-dialysis patients are higher than pre-dialysis.","PeriodicalId":347161,"journal":{"name":"International Journal of Computing and Corporate Research","volume":"536 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124943769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cerebral abscess caused by Streptococcus agalactiae, an unusual presentation 无乳链球菌引起的脑脓肿，一种不寻常的表现
International Journal of Computing and Corporate Research Pub Date : 2021-01-04 DOI: 10.31579/2690-4861/085
A. Fuentes
{"title":"Cerebral abscess caused by Streptococcus agalactiae, an unusual presentation","authors":"A. Fuentes","doi":"10.31579/2690-4861/085","DOIUrl":"https://doi.org/10.31579/2690-4861/085","url":null,"abstract":"During the first three months of life, Group B streptococcus or Agalactiae (GBS) can cause meningitis and be associated with cerebrovascular accidents resulting from sepsis and infection of the central nervous system. This article presents the unusual case of a female infant who was afflicted with GBS, meningitis, sepsis complicated by septic shock, ischemic lesions secondary to inflammatory vasculitis and a cerebral abscess accompanied by epileptic seizures with a hypsarrythmia electroencephalographic pattern. A long-term NICU stay with antibiotic management, inotropic support and antiepileptic treatment succeeded in resolving the acute stage of the illness. Out-patient follow-up revealed increased muscle-tone, but delayed neurological development. While this improved significantly with integral rehabilitative therapy, a slight delay still remained. Neuroimaging follow-up at 18 months found malacia-area and core retractions in the left caudate nucleus.","PeriodicalId":347161,"journal":{"name":"International Journal of Computing and Corporate Research","volume":"141 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115016964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quantitative Methods for Alkaline Protease Determination and its Applications: A Comprehensive Review 碱性蛋白酶的定量测定方法及其应用综述
International Journal of Computing and Corporate Research Pub Date : 2021-01-04 DOI: 10.31579/2690-4861/072
H HomadyM.
{"title":"Quantitative Methods for Alkaline Protease Determination and its Applications: A Comprehensive Review","authors":"H HomadyM.","doi":"10.31579/2690-4861/072","DOIUrl":"https://doi.org/10.31579/2690-4861/072","url":null,"abstract":"Proteases break peptide bonds. It is often necessary to measure and/or compare the activity of alkaline proteases using different procedures in the lab. Many studies with keen interest on alkaline proteases mostly use quantitative and/or qualitative assay methods to assay the enzyme activity of proteases. There is need to select a suitable assay method from the reported ones which will be ideal for any proposed study. There could be challenges when choosing the right assay method from the existing ones, thereby prompting the need for a review of the various methods for the quantitative assay of alkaline protease, the quantitative methods and protocols used from 1938 until now and their industrial applications were chronologically reviewed.","PeriodicalId":347161,"journal":{"name":"International Journal of Computing and Corporate Research","volume":"89 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123531136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pakistani youth population is prone to SARS-CoV-2 (nCoVID-19) Infection 巴基斯坦青年人群易感染新冠肺炎
International Journal of Computing and Corporate Research Pub Date : 2020-12-29 DOI: 10.31579/2690-4861/083
S. Afridi
{"title":"Pakistani youth population is prone to SARS-CoV-2 (nCoVID-19) Infection","authors":"S. Afridi","doi":"10.31579/2690-4861/083","DOIUrl":"https://doi.org/10.31579/2690-4861/083","url":null,"abstract":"Saifullah Afridiand Daniel C. Hoessli Department of Pediatric Intensive Care Unit, Guangzhou Institute of Pediatrics, Guangzhou Women and Children's Medical Center, Joint Center for Infection and Immunity,Guangzhou, Medical University, 510623, Guangzhou, China. The Center for Microbes, Development and Health, Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai, China. Department of Biological Sciences (DBS), National University of Medical Sciences (NUMS),Secretariat c/o Military Hospital, Adjacent to Armed Force Institute of Cardiology, Rawalpindi, Pakistan. Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi-75270, Pakistan. *Correspondence Author: Saifullah Afridi, Ph.D. Department of Biological Sciences (DBS), National University of Medical Sciences (NUMS), Secretariat c/o Military Hospital, Adjacent to Armed Force Institute of Cardiology, Rawalpindi, Pakistan. Received date: September 23, 2020; Accepted date: December 23, 2020; Published date: December 30, 2020 Citation: S Afridi and Daniel C. Hoessli. (2020) Pakistani youth population is prone to SARS-CoV-2 (nCoVID-19) Infection. International Journal of Clinical Case Reports and Reviews. 5(1); DOI:10.31579/2690-4861/083 Copyright: © 2020 Saifullah Afridi, This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.","PeriodicalId":347161,"journal":{"name":"International Journal of Computing and Corporate Research","volume":"43 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117307550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Post typhoid retinitis and neurosensory detachment 伤寒后视网膜炎与神经感觉脱离
International Journal of Computing and Corporate Research Pub Date : 2020-12-29 DOI: 10.31579/2690-4861/080
Prarthana Gokarn
{"title":"Post typhoid retinitis and neurosensory detachment","authors":"Prarthana Gokarn","doi":"10.31579/2690-4861/080","DOIUrl":"https://doi.org/10.31579/2690-4861/080","url":null,"abstract":"Typhoid fever is an acute infectious disease capable of rarely producing ocular complications. These complications are usually seen after the third week, and is notoriously called, as the \"Week of complications\" by direct invasion or by allergic immune mediated reactions. It can present as uveitis, vasculitis, choroiditis, endophthalmitis or panophthalmitis. We here present an 18 year old boy presenting as retinitis with severe exudation and neurosensory detachment and which was managed successfully with steroids.","PeriodicalId":347161,"journal":{"name":"International Journal of Computing and Corporate Research","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132770764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Left Ventricular Aneurysm: The Cardiologist Prevent, the Surgical Team Treats 左心室动脉瘤:心脏病专家预防，外科团队治疗
International Journal of Computing and Corporate Research Pub Date : 2020-12-07 DOI: 10.31579/2690-4861/084
M. Elharras
{"title":"The Left Ventricular Aneurysm: The Cardiologist Prevent, the Surgical Team Treats","authors":"M. Elharras","doi":"10.31579/2690-4861/084","DOIUrl":"https://doi.org/10.31579/2690-4861/084","url":null,"abstract":"Left ventricular aneurysms, both true and pseudo aneurysm, are a consequence of coronary heart disease. Trans thoracic echography is the gold standard in the assessment of the left ventricular aneurysm; the most frequent complication is the development of blood stasis and left ventricular thrombi with the risk of systemic embolization, the use of long-term oral anticoagulant therapy is controversal , Left ventricular aneurysm surgery , often with myocardial revascularization, is indicated in well-defined cases, with several surgical technique, depending on the type of aneurysm, the anatomical caractehristics and the team skill’s, we report in this article tow cases of the left ventricular aneurysm . Key word: left ventricular aneurysms; pseudo aneurysm; coronary artery disease; ventricular thrombi; systemic embolization","PeriodicalId":347161,"journal":{"name":"International Journal of Computing and Corporate Research","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115910251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cerebral Infarction Caused by Thrombolytic Therapy for Acute Myocardial Infarction a Case Report and Literature Review 急性心肌梗死溶栓治疗致脑梗死1例报告并文献复习
International Journal of Computing and Corporate Research Pub Date : 2020-11-23 DOI: 10.31579/2690-4861/091
Wei Liu
{"title":"Cerebral Infarction Caused by Thrombolytic Therapy for Acute Myocardial Infarction a Case Report and Literature Review","authors":"Wei Liu","doi":"10.31579/2690-4861/091","DOIUrl":"https://doi.org/10.31579/2690-4861/091","url":null,"abstract":"Background: Thrombolytic therapy is one of the effective treatments for ST-segment elevation myocardial infarction. The most common complication of thrombolytic therapy is hemorrhage. Thromboembolism caused by thrombolytic therapy is exceedingly rare in clinical practice. However, we report a case of cerebral infarction caused by thrombolytic therapy for acute myocardial infarction. Case Report: A 70-year-old man complained of burning sensation under the xiphoid process for 7 years and sudden chest pain for 3 hours. He was diagnosed with acute anterior ST-segment elevation myocardial infarction. Thrombolytic therapy was carried out immediately, but the patient developed cerebral infarction 3 hours after thrombolysis. CONCLUSION: The common complication of thrombolytic therapy is cerebral hemorrhage or gastrointestinal hemorrhage, but the possibility of cerebral infarction should also be taken into account when patients have neurological symptoms.","PeriodicalId":347161,"journal":{"name":"International Journal of Computing and Corporate Research","volume":"59 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130998280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acute antibody mediated rejection associated with acute herpetic gingiva-stomatitis in kidney transplant patient: A case report 肾移植患者急性疱疹性龈口炎与急性抗体介导排斥反应相关1例报告
International Journal of Computing and Corporate Research Pub Date : 2020-11-23 DOI: 10.31579/2690-4861/070
U. Din
{"title":"Acute antibody mediated rejection associated with acute herpetic gingiva-stomatitis in kidney transplant patient: A case report","authors":"U. Din","doi":"10.31579/2690-4861/070","DOIUrl":"https://doi.org/10.31579/2690-4861/070","url":null,"abstract":"Introduction: Antibody-mediated rejection (AMR) is the most serious cause of renal allograft loss. Most of the acute AMR attacks occur within the first week post-transplant. Subject: In this case report, we present a case of AMR that occurred five months post-transplant in association with acute oral viral infection. This patient had history of bone marrow hypoplasia two months following onset of hemodialysis and was maintained on cyclosporine and prednisolone beside switch to hirudin as anticoagulant. During that period, she also received 6 units of whole blood till she underwent kidney transplant after 2 years on dialysis. The post-transplant course was uneventful till the patient developed severe acute herpetic gingivastomatitis 5 months posttransplant that was associated with abrupt rise of renal chemistry. Biopsy proven AMR showed resistance to treatment with plasma exchange [PE] and Intravenous immunoglobulins. The patient was readmitted to regular hemodialysis unit for 2 months together with minimization of immunosuppressive treatment. Outcome: During routine follow-up investigations, kidney function tests became near to the pre-rejection levels. We discontinued dialysis and re-administered the initial immunosuppressive regimen. Conclusion: This is the first reported case of AMR in association with acute Herpes simplex infection that shows delayed spontaneous recovery.","PeriodicalId":347161,"journal":{"name":"International Journal of Computing and Corporate Research","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122224753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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