Bulletin of Pharmaceutical Sciences. Assiut最新文献_第9页

ESSENTIAL OIL COMPOSITION AND CYTOTOXICITY OF Decaspermum parviflorum (Lam.) A.J.Scott FROM MALAYSIA 小檗精油成分及细胞毒性研究a·j·斯科特，马来西亚

Bulletin of Pharmaceutical Sciences. Assiut Pub Date : 2022-12-01 DOI: 10.21608/bfsa.2022.271589

Wan Mohd Nuzul Hakimi Wan Salleh, N. Ghani, Abu-Baker bdel-Aal

引用次数: 0

EVALUATION OF RHEUM PALMATUM RHIZOMES AVAILABLE IN JORDANIAN MARKETS AND INVESTIGATION OF ITS POTENTIAL USE AS HAIR DYE COSMETICS 评估可在约旦市场的大黄掌根茎和调查其作为染发剂化妆品的潜在用途

Bulletin of Pharmaceutical Sciences. Assiut Pub Date : 2022-12-01 DOI: 10.21608/bfsa.2022.271541

L. Al-Halaseh, M. A. Abu Hajleh, A. Al-Samydai, Siba Majali, R. Issa, R. Said, Mai A. M. Ahmed

{"title":"EVALUATION OF RHEUM PALMATUM RHIZOMES AVAILABLE IN JORDANIAN MARKETS AND INVESTIGATION OF ITS POTENTIAL USE AS HAIR DYE COSMETICS","authors":"L. Al-Halaseh, M. A. Abu Hajleh, A. Al-Samydai, Siba Majali, R. Issa, R. Said, Mai A. M. Ahmed","doi":"10.21608/bfsa.2022.271541","DOIUrl":"https://doi.org/10.21608/bfsa.2022.271541","url":null,"abstract":"Context: Dyeing hair with natural components derived from plant material is a common practice since ancient time. Variable colour shadows obtained from different plant extracts. The folkloric practices need optimization to find alternatives for the chemical dyes, which carry loads of health hazards. For decades, people use Rhubarb roots extract in treating chronic constipation and other minor health disorders. The pharmacological effects refer to their active constituents; anthraquinone glycosides. Hair dyeing properties of Rhubarb roots extracts need further scientific investigations. Aims: To evaluate the hair-dyeing properties of rhubarb's aqueous extract as an eco-friendly alternative to the commercially available hair dyes and to measure the fastness of the produced colour in different conditions . Methods: Identification of the plant material was done according to international specifications. Wool pieces dyed by aqueous extracts of rhubarb's roots and rhizomes under different conditions. Variables that might be affecting the dyeing process such as concentration, pH, using colour mordant, swelling agent, and dyeing time were studied. Spectroscopic methods used to record colourfastness measurements. Results and Conclusion: The extract of rhubarb roots and rhizomes show good dyeing properties. The obtained colours were pale yellow, intense yellow and pink. Colour fastness is enhanced and optimized using 2 mg/ml concentration, 2 h dyeing time, acidic pH, adding mordant and pretreating the fibres with a swelling agent.","PeriodicalId":345040,"journal":{"name":"Bulletin of Pharmaceutical Sciences. Assiut","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116391865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

NANOSTRUCTURED LIPOSOMES FOR NOSE TO BRAIN DELIVERY OF CARMUSTINE: IN VIVO EVALUATION 纳米结构脂质体用于鼻到脑输送卡莫司汀:体内评价

Bulletin of Pharmaceutical Sciences. Assiut Pub Date : 2022-12-01 DOI: 10.21608/bfsa.2022.271485

G. Vani, M. Alagusundaram, K. B. Sekhar

{"title":"NANOSTRUCTURED LIPOSOMES FOR NOSE TO BRAIN DELIVERY OF CARMUSTINE: IN VIVO EVALUATION","authors":"G. Vani, M. Alagusundaram, K. B. Sekhar","doi":"10.21608/bfsa.2022.271485","DOIUrl":"https://doi.org/10.21608/bfsa.2022.271485","url":null,"abstract":"Nano sized particles are promising mediators for the administration of active compounds in the nasal and cerebral systems. However, the ability to achieve relevant therapeutic concentrations of exogenous molecules in the body is dependent mainly on the capability of nanoparticles to break down biological obstructions. In this work, nanoscale formulations conveying the minimally soluble model drug Carmustine (CS) were discussed. Box Behnken design (QbD tool) was applied to predict the interactions between the independent variable (drug-lipid ratio (X1), cholesterol (X2) and Critical Process Parameters (sonication time, X3) on the dependent variable (Entrapment efficiency (Y1), Particle size (Y2) and in vitro drug release (Y3)). The nano scale liposomal optimized Carmustine formulation (NSL-OCS) was investigated for their effect on the biopharmaceutical facets decisive for nose-to-brain delivery such as permeation across the nasal mucosa. An in vivo pharmacokinetic study was performed in Wistar albino rats via intravenous routes. Histopathologic studies support the absence of evidence of toxicity. In vitro drug dissemination studies show rapid drug release followed by extended release of CS for up to 24 hrs. The Pharmacokinetic parameters of NSLs in brain were higher in intranasal route compared to NSLs administered by intravenous route. The findings showed that the intranasal pathway can be an effective approach to administering the drug straight to the brain and improve the drug's efficacy in the brain to treat brain tumors and become a good substitute to oral medication.","PeriodicalId":345040,"journal":{"name":"Bulletin of Pharmaceutical Sciences. Assiut","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117283272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

ASTRAZENECA AND SINOPHARM VACCINES ADVERSE EFFECTS AT FIRST AND SECOND DOSES. CROSS SECTIONAL STUDY EGYPTIAN EXPERIENCE 阿斯利康和国药控股的疫苗在第一次和第二次注射时的不良反应。横断面研究埃及的经验

Bulletin of Pharmaceutical Sciences. Assiut Pub Date : 2022-12-01 DOI: 10.21608/bfsa.2022.271642

Noha A. El-Bassiouny, Amira B. Kassem, M. Abd-Alhaseeb, M. Tolba

{"title":"ASTRAZENECA AND SINOPHARM VACCINES ADVERSE EFFECTS AT FIRST AND SECOND DOSES. CROSS SECTIONAL STUDY EGYPTIAN EXPERIENCE","authors":"Noha A. El-Bassiouny, Amira B. Kassem, M. Abd-Alhaseeb, M. Tolba","doi":"10.21608/bfsa.2022.271642","DOIUrl":"https://doi.org/10.21608/bfsa.2022.271642","url":null,"abstract":"Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel coronavirus that causes severe acute respiratory syndrome (SARS). It was discovered in December 2019 in Wuhan, China., which subsequently led to a nationwide outbreak. The World Health Organization included the AstraZeneca and Sinopharm vaccines for the WHO Emergency Use List on February 16 and May 7, 2021, respectively. Egyptians have gotten 2,623,200 doses of AstraZeneca's COVID-19 vaccination plus 500,000 doses of Sinopharm vaccine. The trial would test the vaccinations' short-term side effects on Egyptian people aged 18 and older. Result(s): Most symptoms decreased significantly after the second dose when compared to symptoms seen at the first dose .In addition, both doses reduced symptoms significantly compared to the first dose.Interestingly, the desire to sleep appears to significantly increase the side effects again after both doses when compared to the second dose alone. The majority or nearly all of the participants (96.5%) had no infection after vaccination. Conclusion(s): Mild to moderate side effects are to be expected after the vaccination process because the body's immunomodulatory instructions can lead to negative symptoms. Symptoms include injection site soreness, fever, tiredness, headache, muscle aches, chills, and diarrhoea.. The majority or nearly all of the participants (96.5%) had no infection after vaccination. Training and continuing education are needed to improve universal vaccine acceptance and reduce frequency. Copyright © 2022 Assiut University. All rights reserved.","PeriodicalId":345040,"journal":{"name":"Bulletin of Pharmaceutical Sciences. Assiut","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125699214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

PHYTOCHEMICAL SCREENING AND PHARMAOCOLOGICAL EVALUATION OF TECOMA GAUDICHAUDI 毛茛的植物化学筛选及药理学评价

Bulletin of Pharmaceutical Sciences. Assiut Pub Date : 2022-12-01 DOI: 10.21608/bfsa.2022.271489

Alekhya Veeramaneni, T. Deepan, S. Ganapaty

引用次数: 0

CHROMATOGRAPHIC ISOLATION, IDENTIFICATION AND CHARACTERIZATION OF SOME CHEMICAL CONSTITUENTS OF PETROSELINUM CRISPUM LEAVES AND EVALUATING AS HEPATOPROTECTIVE AGENTS 石竹叶部分化学成分的色谱分离、鉴定、表征及保肝作用评价

Bulletin of Pharmaceutical Sciences. Assiut Pub Date : 2022-12-01 DOI: 10.21608/bfsa.2022.271594

N. Metwally, M. El-Sayed, E. Morsi, Tarek Abou-Shousha, Bassant Abdel-Wahab, H. Abdel-Hady

{"title":"CHROMATOGRAPHIC ISOLATION, IDENTIFICATION AND CHARACTERIZATION OF SOME CHEMICAL CONSTITUENTS OF PETROSELINUM CRISPUM LEAVES AND EVALUATING AS HEPATOPROTECTIVE AGENTS","authors":"N. Metwally, M. El-Sayed, E. Morsi, Tarek Abou-Shousha, Bassant Abdel-Wahab, H. Abdel-Hady","doi":"10.21608/bfsa.2022.271594","DOIUrl":"https://doi.org/10.21608/bfsa.2022.271594","url":null,"abstract":"Petroselinum crispum Mill. (family Apiaceae) is widely used as an essential spice due to its health benefits. This study aimed to investigate the constituents of P . crispum aerial parts and evaluate its hepatoprotective activity. Ethyl acetate and n-butanol fractions of P. crispum subjected to different chromatographic separation techniques. The compounds were identified on the basis of spectral data and compared with previously reported data. Also, the methanolic extract and n-butanol fraction were evaluated for in-vivo hepatoprotective activity against carbon tetrachloride (CCl 4 ) induced hepatotoxicity in mice (10 groups; 8 mice/group). All groups intraperitonially injected by CCl 4 (0.5mg/kg b.w., i.p.) in single dose at 11th day, the treated groups received (100, 200, 300, 400 mg/kg b.w.) of MeOH extract and BuOH fraction separately for 14 days. The results revealed that seven compounds were isolated from EtOAc and n-BuOH fractions which were identified as β-sitosterol (1), quercetin (2), isorhmentin (3), apigenin (4), apigenin-7-O-β-D-glucopyranoside (cosmosiin) (5), diosmetin-7-O-β-D-glucopyranoside (6), apigenin 7-O-β- D- apiofuranosyl (1→2)-β- D glucopyranoside (apiin) (7). On other hand, CCl 4 – induced hepatotoxicity cleared in severe liver damage, showed elevation of liver enzymes. The MeOH extract and n-BuOH fraction exhibited significant hepatoprotection in improvement liver enzymes, with a propensity to return to near-normal levels. So, P. crispum extracts are promising in-vivo hepatoprotective activity.","PeriodicalId":345040,"journal":{"name":"Bulletin of Pharmaceutical Sciences. Assiut","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128506810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

IN SILICO DESIGN AND VALIDATION OF A NOVEL PCR-RFLP ASSAY FOR GPRC6A RS2247911 POLYMORPHISM INVOLVED IN MALE INFERTILITY gprc6a rs2247911多态性与男性不育相关的新型pcr-rflp检测方法的设计和验证

Bulletin of Pharmaceutical Sciences. Assiut Pub Date : 2022-12-01 DOI: 10.21608/bfsa.2022.271821

K. Jawich, M. Alhalabi, S. Al Fahoum

{"title":"IN SILICO DESIGN AND VALIDATION OF A NOVEL PCR-RFLP ASSAY FOR GPRC6A RS2247911 POLYMORPHISM INVOLVED IN MALE INFERTILITY","authors":"K. Jawich, M. Alhalabi, S. Al Fahoum","doi":"10.21608/bfsa.2022.271821","DOIUrl":"https://doi.org/10.21608/bfsa.2022.271821","url":null,"abstract":"Male infertility is a prevalent disorder affecting approximately 7% of the male population, at least 2,000 genes are involved in spermatogenesis, availability of genetic investigations is a challenge in developing countries, GPRC6A, G-protein coupled receptor, activated by Osteocalcin (OCN)an osteoblast secreted hormone, is a master regulator of a complex metabolic and reproductive networks. rs2247911 in GPRC6A plays a role in male fertility and glucose metabolism, Although DNA sequencing is regarded the golden standard tool for genotyping, it is less affordable in developing world laboratories, polymerase chain reaction– restriction fragment length polymorphism (PCR-RFLP) assay is an inexpensive and highly valuable tool for genotyping, this study aimed to develop (PCR-RFLP) method for assessment of rs2247911 polymorphism.10% of male subjects genotyped previously by sequencing were genotyped the by PCR-RFLP method based on Geneious® bioinformatics tool suggested restriction enzyme (ScrFI), PCR-RFLP 100% correctly identified genotypes. we present for the first time an accurate and inexpensive method for genotyping rs2247911.","PeriodicalId":345040,"journal":{"name":"Bulletin of Pharmaceutical Sciences. Assiut","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129836655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

EVALUATION OF THE SAFETY AND RESISTANCE ASSOCIATED VARIANTS OF SOFOSBUVIR/DACLATASVIR AMONG EGYPTIAN PATIENTS WITH HEPATITIS C VIRUS: A PROSPECTIVE STUDY 评估索非布韦/ daclatasvir在埃及丙型肝炎病毒患者中的安全性和耐药性:一项前瞻性研究

Bulletin of Pharmaceutical Sciences. Assiut Pub Date : 2022-12-01 DOI: 10.21608/bfsa.2022.271826

H. Ramadan, Soha Saoud Abdel-Monem, A. Ahmed, Rasha, Maree Omar, H. R. Ahmed, H. Hetta

{"title":"EVALUATION OF THE SAFETY AND RESISTANCE ASSOCIATED VARIANTS OF SOFOSBUVIR/DACLATASVIR AMONG EGYPTIAN PATIENTS WITH HEPATITIS C VIRUS: A PROSPECTIVE STUDY","authors":"H. Ramadan, Soha Saoud Abdel-Monem, A. Ahmed, Rasha, Maree Omar, H. R. Ahmed, H. Hetta","doi":"10.21608/bfsa.2022.271826","DOIUrl":"https://doi.org/10.21608/bfsa.2022.271826","url":null,"abstract":"Background : Hepatitis C virus (HCV) is a major health problem. Current treatment by direct-acting antivirals achieved high sustained virological response (SVR). However, drug intolerance or relapse may occur. We aimed to demonstrate the safety of sofosbuvir (SOF) plus daclatasvir (DCV) regimen in Egyptian patients with hepatitis C infection and the assessment of resistance associated variants (RAVs) in non-responders. Methods: In this prospective study, 850 HCV patients eligible to SOF + DCV ± ribavirin (RBV) were recruited. They were divided into two groups; patients with chronic hepatitis C (CHC) and patients with liver cirrhosis. Baseline data included clinical history, examination, routine laboratory tests and HCV viral load. Safety evaluation was assessed during treatment up to 12 weeks after the end of treatment. RAVs assessment was considered at baseline and in cases of relapse. Results : CHC group included 548 patients while 302 had liver cirrhosis. The most frequent adverse events were headache 20%, fatigue 14%, myalgia 5.2%. Diarrhea occurred in 4.6% with significantly higher frequency among liver cirrhosis group; 7.3% vs. 3.1% (P= 0.04). No patients had to stop treatment because of adverse events. SVR was achieved in 91.2% while 75 (8.8%) had relapse. At baseline, RAVs were found in 10%. After therapy, RAVs (E237D) were detected in 1 non-responder. Conclusion: Treatment with SOF/DCV was effective and well tolerated in patients with HCV. RAVs testing is not routinely recommended before treatment as resistant variants could occur naturally in HCV.","PeriodicalId":345040,"journal":{"name":"Bulletin of Pharmaceutical Sciences. Assiut","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122331128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

EVALUATION OF CURRENT PRACTICE OF STRESS ULCER PROPHYLAXIS IN PATIENTS ADMITTED TO INTENSIVE CARE UNITS IN THE GAZA STRIP- PALESTINE 评估加沙地带-巴勒斯坦重症监护病房收治的病人目前预防应激性溃疡的做法

Bulletin of Pharmaceutical Sciences. Assiut Pub Date : 2022-12-01 DOI: 10.21608/bfsa.2022.271660

Hala Alagha, Nasaem Mohammed Al Mabhouh

{"title":"EVALUATION OF CURRENT PRACTICE OF STRESS ULCER PROPHYLAXIS IN PATIENTS ADMITTED TO INTENSIVE CARE UNITS IN THE GAZA STRIP- PALESTINE","authors":"Hala Alagha, Nasaem Mohammed Al Mabhouh","doi":"10.21608/bfsa.2022.271660","DOIUrl":"https://doi.org/10.21608/bfsa.2022.271660","url":null,"abstract":"This study aimed at assessing the degree of adherence of Stress ulcer prophylaxis (SUP) practice to the American Society of Health-System Pharmacists (ASHP) guidelines in intensive care units (ICUs) at three hospitals in the Gaza Strip, Palestine. This was a prospective study that utilized chart review methodology for data collection. Four aspects of SUP practice were assessed: indication, dose, route of administration and duration. The study enrolled 442 ICU patients with a median (Interquartile range, IQR) age of 49.0 (36.6) years. More than half the patients (55.7%) were males. Coagulopathy was the most common major risk factor for stress ulcer, presented in 73 (16.5%) patients, while the use of corticosteroid therapy was the most common minor risk factor presented in 93 (21%) patients. SUP was administered to 426 (96.4%) patients, of which 86.9% received ranitidine and 13.1% received PPIs. Overall adherence and indication adherence rates to guidelines were 16.7% and 36.4%, respectively. Appropriate dose, route and duration of SUP were found in 63.6%, 68.2%, and 88.1% of the evaluated doses, respectively. Of the 426 patients prescribed SUP, 48 (11.3%) developed adverse effects. This study revealed suboptimal SUP practice in the investigated hospitals and the need to apply strategies to improve SUP use patterns.","PeriodicalId":345040,"journal":{"name":"Bulletin of Pharmaceutical Sciences. Assiut","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125456122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

ANTI-INFLAMATORY AND ANTI-LIPID PEROXODATION POTENTIALS OF SALVIA CHUDAEI BATT. et TRAB. AND LAVANDULA ANTINEAE MAIRE: ENDEMIC PLANTS FROM ALGERIAN SAHARA 丹参的抗炎和抗脂质过氧化作用。et TRAB。还有薰衣草:阿尔及利亚撒哈拉沙漠的特有植物

Bulletin of Pharmaceutical Sciences. Assiut Pub Date : 2022-12-01 DOI: 10.21608/bfsa.2022.271588

S. Krimat, Ahmed Nouasri, Aicha Ksouri, H. Metidji, Chafia Tigrine, T. Dob

{"title":"ANTI-INFLAMATORY AND ANTI-LIPID PEROXODATION POTENTIALS OF SALVIA CHUDAEI BATT. et TRAB. AND LAVANDULA ANTINEAE MAIRE: ENDEMIC PLANTS FROM ALGERIAN SAHARA","authors":"S. Krimat, Ahmed Nouasri, Aicha Ksouri, H. Metidji, Chafia Tigrine, T. Dob","doi":"10.21608/bfsa.2022.271588","DOIUrl":"https://doi.org/10.21608/bfsa.2022.271588","url":null,"abstract":"The present study was undertaken to investigate the anti-inflammatory and anti-lipid peroxidation activities of two endemic plants of the central Sahara; Salvia chudaei Batt. et Trab and Lavandula antineae Maire (Lamiaceae), as well as their chemical composition of hydromethanolic extracts. In the test of carrageenan-induced oedema in mice, L. antineae extract, at the dose of 200 mg/kg, revealed good anti-inflammatory activity (P˂0.05) showing 80.74% reduction in the paw thickness comparable to that produced by the standard drug aspirin an83.44% at 4h, while S. chudaei extract was found to have moderate activity (50.74%). When the plant extracts were applied topically at a dosage of 1 and 2 mg per ear, the reduction of ear oedema inflammation was very remarkable compared to the mice of the control group. The plant extracts also showed anti-lipid peroxidation activity with no significant difference compared to ascorbic acid (77.63 ± 1.58%). In addition, the chemical characterization of two extracts by HPLC-DAD revealed the presence of various phenolic acids and flavonoids. These findings showed that Lavandula antineae and Salvia chudaei displays remarkable anti-inflammatory and anti-lipid peroxidation activities and hence can be potential natural sources in health and medicine.","PeriodicalId":345040,"journal":{"name":"Bulletin of Pharmaceutical Sciences. Assiut","volume":"131 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126862645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0