H. Ahmed, Hamada Mohamed, M. Taha, Bahaa-Eldin Anwar, Ibrahim H. Mahmoud
{"title":"Analysis of bacterial community and its biodegradation ability of 17-β estradiol in wastewater plant in Assiut, Upper Egypt","authors":"H. Ahmed, Hamada Mohamed, M. Taha, Bahaa-Eldin Anwar, Ibrahim H. Mahmoud","doi":"10.21608/bfsa.2023.210589.1745","DOIUrl":"https://doi.org/10.21608/bfsa.2023.210589.1745","url":null,"abstract":"","PeriodicalId":345040,"journal":{"name":"Bulletin of Pharmaceutical Sciences. Assiut","volume":"117 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122623115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. Jebur, Baraa Abd Al-Kareem, Hasan Ikareim Idbeis, Juheb Akhter, Shekh Mohammad Afzal, Naushad Khan, Khloud Gamal Abdelsalam, Wassan Qasim Qadim, Ban Qaddorri, Ban Alaa Muhaisen
{"title":"Lung Histo-Pathological Changes and SODs Gene Expression in Wister Rats Exposed to Conventional and Electronic Cigarettes","authors":"H. Jebur, Baraa Abd Al-Kareem, Hasan Ikareim Idbeis, Juheb Akhter, Shekh Mohammad Afzal, Naushad Khan, Khloud Gamal Abdelsalam, Wassan Qasim Qadim, Ban Qaddorri, Ban Alaa Muhaisen","doi":"10.21608/bfsa.2023.215969.1765","DOIUrl":"https://doi.org/10.21608/bfsa.2023.215969.1765","url":null,"abstract":"","PeriodicalId":345040,"journal":{"name":"Bulletin of Pharmaceutical Sciences. Assiut","volume":"159 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123101660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. Mando, Ahmad Hassan, Ghassan Abo Chameh, Nathalie Moussa
{"title":"Quality Assessment of Herbal Medicinal Products in BPH: Chemical Markers and Fingerprint Analysis","authors":"H. Mando, Ahmad Hassan, Ghassan Abo Chameh, Nathalie Moussa","doi":"10.21608/bfsa.2023.207758.1733","DOIUrl":"https://doi.org/10.21608/bfsa.2023.207758.1733","url":null,"abstract":"","PeriodicalId":345040,"journal":{"name":"Bulletin of Pharmaceutical Sciences. Assiut","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130558522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of Colocasia esculenta (L.) Schott (Araceae) ethanol leaf extract on sperm concentration in male Wistar rats","authors":"T. Ajayi, G. Alade, J. Kemelayefa, K. Ajibesin","doi":"10.21608/bfsa.2023.197797.1685","DOIUrl":"https://doi.org/10.21608/bfsa.2023.197797.1685","url":null,"abstract":"Colocasia esculenta (L.) Schott (Araceae) is a staple food which supply needed nutrients in Africa and is therefore, employed in ethnomedicine. This study aimed to evaluate the effect of the leaf ethanol extract as well as its partitioned fractions (ethyl acetate, butanol and aqueous) on some male reproductive parameters such as sperm count, motility and morphology as well as the histology of testes in male Wistar rats after 15 days of administration of the extracts/fractions. The ethanol extract showed significant increases of 66 and 213% in sperm concentration at 500 and 1000 mg/kg respectively. This activity was largely retained in the ethylacetate with 200, 213 and 300% in sperm concentration at 50, 100 and 200 mg/kg, respectively and aqueous fractions with 274 and 657% increase at 50 and 100 mg/kg, respectively. Motility and morphology were not significantly altered. The histology of the tests revealed that spermatozoa cells were the positively affected cells.","PeriodicalId":345040,"journal":{"name":"Bulletin of Pharmaceutical Sciences. Assiut","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120990751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Imane Ould Amer, S. M. Selles, Hocine Laaredj, Abdelkader Dilmi Bouras, Yamina Kadari
{"title":"Chemical composition and biological activity of Allium sativum L. essential oil against MDR bacteria isolated from buccal cavity affected by caries","authors":"Imane Ould Amer, S. M. Selles, Hocine Laaredj, Abdelkader Dilmi Bouras, Yamina Kadari","doi":"10.21608/bfsa.2023.206515.1721","DOIUrl":"https://doi.org/10.21608/bfsa.2023.206515.1721","url":null,"abstract":"","PeriodicalId":345040,"journal":{"name":"Bulletin of Pharmaceutical Sciences. Assiut","volume":"147 5","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120897445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A validated RP-HPLC method for separation and determination of Etoricoxib and Paracetamol in bulk and pharmaceutical dosage form","authors":"Lama Ghazal, Mhd Almardini, I. Allous","doi":"10.21608/bfsa.2023.194316.1670","DOIUrl":"https://doi.org/10.21608/bfsa.2023.194316.1670","url":null,"abstract":"Etoricoxib is a non-steroidal, anti-inflammatory drug (NSAID) and a selective inhibitor of Cyclooxygenase 2 (COX2), which makes it safer on the gastrointestinal tract than the other NSAIDs. Given the importance of Etoricoxib’s, its combination with paracetamol offers higher efficacy and fewer side effects. In addition to the popularity of this combination in the pharmaceutical industry and the diversity of its manufacturing companies","PeriodicalId":345040,"journal":{"name":"Bulletin of Pharmaceutical Sciences. Assiut","volume":"67 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132571623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Mirza, Poonam Sharma, G. Kulkarni, Bhupesh Sharma
{"title":"Spironolactone Alters the Levels of Neuronal Function Markers in Autistic Rats","authors":"R. Mirza, Poonam Sharma, G. Kulkarni, Bhupesh Sharma","doi":"10.21608/bfsa.2023.171519.1563","DOIUrl":"https://doi.org/10.21608/bfsa.2023.171519.1563","url":null,"abstract":"Autism spectrum disorder (ASD) is a neurodevelopmental disorder that is characterized by repetitive behavior and impairment in social behavior. ASD is a complex disorder with complex etiology that involves multiple genes, environmental factors","PeriodicalId":345040,"journal":{"name":"Bulletin of Pharmaceutical Sciences. Assiut","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127831604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Z. Lakache, Hamza Aliboudhar, Affaf Laassami, Hafitha Metidji, Hinda Hacib, Hassina Tounssi, Abdelkrim Kammeli
{"title":"EVALUATION OF ANTIOXIDANT, ANTIBACTERIAL, ANTALGIC AND ANTI-INFLAMMATORY PROPERTIES OF CRATAEGUS AZAROLUS.","authors":"Z. Lakache, Hamza Aliboudhar, Affaf Laassami, Hafitha Metidji, Hinda Hacib, Hassina Tounssi, Abdelkrim Kammeli","doi":"10.21608/bfsa.2023.201923.1697","DOIUrl":"https://doi.org/10.21608/bfsa.2023.201923.1697","url":null,"abstract":"The purpose of this study was to examine the potential effects of a Crataegus azarolus extract on antioxidant, antibacterial, analgesic, and anti-inflammatory activities. Additionally, a phytochemical analysis was conducted to identify the chemical constituents of the extract. The antioxidant potential was assessed using DPPH, FRAP, and β-carotene assays, while the antibacterial activity was evaluated against five different microorganisms by measuring the diameter of inhibition zones. The anti-inflammatory and analgesic effects were examined by inducing paw edema with carrageenan and intraperitoneal injection of acetic acid, respectively. The results indicated that the extract exhibited strong antioxidant activity, and the highest antibacterial activity was observed against Bacillus subtilis, with an inhibition zone diameter of 18 mm. Additionally, administering 400 mg/kg of the extract resulted in a strong inhibition of paw edema, showing a percentage reduction of 42.28% compared to the control group. Similarly, the methanolic extract (600 mg/kg) of Crataegus azarolus showed inhibition of pain caused by acetic acid in mice. The findings of the study propose that the extract has the potential to provide bioactive compounds, and that its individual constituents may act together in a synergistic manner. Therefore, Crataegus azarolus extract could be used as an alternative to synthetic anti-inflammatory and analgesic compounds in the pharmaceutical industries in the future.","PeriodicalId":345040,"journal":{"name":"Bulletin of Pharmaceutical Sciences. Assiut","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123304518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohamed taher Benmoussa, S. Nadji, A. Bounab, Y. Hadef
{"title":"Phytochemical variability in the essential oil of Matricaria pubescens from Algeria","authors":"Mohamed taher Benmoussa, S. Nadji, A. Bounab, Y. Hadef","doi":"10.21608/bfsa.2023.205144.1713","DOIUrl":"https://doi.org/10.21608/bfsa.2023.205144.1713","url":null,"abstract":"Matricaria pubescens is a plant belonging to the asteraceae family naturally found in Algeria, as well as throughout all of North Africa, commonly used as folk medicine to treat several diseases under several preparations, the essential oil obtained from the aerial parts of the plant contains chemical components, that were determined using GC-MS, the variability in the levels of these components was studied in nine samples collected on different dates from two sites in the northern Sahara of Algeria. 58 components were determined, with different levels, the constituents: Delta.3-Carene, Beta-Ocimene, Allo-Ocimene, (-)-Bornyl acetate, Aromadendrene 2, 4.10(14)-Muuroladien-8 beta-ol, Valencene 2 and Dihydronepetalactone II are shown to be the main chemical components of the essential oil, from the analytical obtained restults, the statistical analysis with HCA and PCA tests have revealed different chemical patterns. Aside from seasonality, chemotypes may be the most important source of variation, and the existence of several varieties featured by different chemical distribution patterns, this outcome should be confirmed by further studies with higher samples.","PeriodicalId":345040,"journal":{"name":"Bulletin of Pharmaceutical Sciences. Assiut","volume":"59 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124186217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hani A. Naseef, Nibal Ayyash, Mayar Almtour, Aseel Shrateeh, Abdallah Abu Khalil, Ni'meh Al-Shami, N. Jaradat, A. Rabba
{"title":"Exploring the role of community pharmacists in drug interactions: A cross-sectional study in Palestine","authors":"Hani A. Naseef, Nibal Ayyash, Mayar Almtour, Aseel Shrateeh, Abdallah Abu Khalil, Ni'meh Al-Shami, N. Jaradat, A. Rabba","doi":"10.21608/bfsa.2023.204364.1709","DOIUrl":"https://doi.org/10.21608/bfsa.2023.204364.1709","url":null,"abstract":"","PeriodicalId":345040,"journal":{"name":"Bulletin of Pharmaceutical Sciences. Assiut","volume":"196 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121314321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}