JAAD International最新文献

{"title":"Comparative outcomes across rituximab induction doses in pemphigus: A real-world single-center study","authors":"Yujia Wang MS, Liangchun Wang MD, Yanyun Jiang MD","doi":"10.1016/j.jdin.2025.11.007","DOIUrl":"10.1016/j.jdin.2025.11.007","url":null,"abstract":"","PeriodicalId":34410,"journal":{"name":"JAAD International","volume":"24 ","pages":"Pages 268-270"},"PeriodicalIF":5.2,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145732992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Burden of acne vulgaris, psoriasis, atopic dermatitis, and urticaria in individuals under 20 years of age in China and globally, 1990-2021: A systematic analysis with 10-year forecast","authors":"Jiawen Wu PhD , Yuanqin Wang MB , Yuxin Qing MD , Bingyang Xu MD , Yan Yang MD , Hong Sun PhD , Na Wu MD","doi":"10.1016/j.jdin.2025.11.018","DOIUrl":"10.1016/j.jdin.2025.11.018","url":null,"abstract":"","PeriodicalId":34410,"journal":{"name":"JAAD International","volume":"24 ","pages":"Pages 323-325"},"PeriodicalIF":5.2,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145924174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A cross-sectional analysis of dermatology resident research productivity in the United States","authors":"Matthew Tao BS , Sean O’Hare BS , Manvinder Suden BS, MS , Mary Grace Hash BS, MS , Frances Case BS , Alex Nguyen , Harris Bolus BS , Garrett Dyess BA , Melodi Javid Whitley MD, PhD","doi":"10.1016/j.jdin.2025.09.013","DOIUrl":"10.1016/j.jdin.2025.09.013","url":null,"abstract":"","PeriodicalId":34410,"journal":{"name":"JAAD International","volume":"24 ","pages":"Pages 199-201"},"PeriodicalIF":5.2,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145615067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Originator versus biosimilar adalimumab in hidradenitis suppurativa: A multicenter real-world analysis of clinical response, maintenance of response, and switching","authors":"Marra Aghajani MBBS, PhD ,&nbsp;James Pham MD ,&nbsp;Tara Sholji MBBS ,&nbsp;Kate Burrell BSc ,&nbsp;Cindy Kok MD, PhD ,&nbsp;John W. Frew MBBS (Hons), MMed, MS, PhD","doi":"10.1016/j.jdin.2025.05.023","DOIUrl":"10.1016/j.jdin.2025.05.023","url":null,"abstract":"<div><h3>Background</h3><div>Adalimumab is a mainstay treatment for hidradenitis suppurativa (HS); however, high-costs limit accessibility. While biosimilars offer an affordable alternative, concerns remain regarding clinical equivalence and the impact of switching.</div></div><div><h3>Objective</h3><div>To evaluate the clinical response of originator versus biosimilar adalimumab in HS and assess outcomes following nonmedical switching.</div></div><div><h3>Methods</h3><div>This multicenter, real-world study included treatment naïve HS patients initiated on originator or biosimilar adalimumab between April 2021 and December 2024. Outcomes were compared between patients remaining on originator and those switched to biosimilar after 16 weeks. Clinical responses were assessed using Hidradenitis Suppurativa Clinical Response 50, Hidradenitis Suppurativa Clinical Response 75, and International Hidradenitis Suppurativa Severity Scoring System 55, with time-to-event analyses evaluating loss of clinical response.</div></div><div><h3>Results</h3><div>Patients on originator adalimumab (<em>n</em> = 186) demonstrated greater proportions of clinical response than biosimilars (<em>n</em> = 127), with time-to-event analysis showing a significant difference between curves (100 vs 52 weeks; hazard ratio = 2.73; <em>P</em> &lt; .0001). Patients switched to biosimilars (<em>n</em> = 71) and experienced higher rates of loss of response than those maintained on originator (<em>n</em> = 71) (50 vs 87 weeks; hazard ratio = 2.42; <em>P</em> = .0003).</div></div><div><h3>Limitations</h3><div>Limitations include its retrospective design and variable biosimilar formulations.</div></div><div><h3>Conclusion</h3><div>Significant differences in clinical response, loss of response, and time-to-event analysis between originator and biosimilar adalimumab in HS underscore the need for consistent treatment and robust monitoring to optimize management.</div></div>","PeriodicalId":34410,"journal":{"name":"JAAD International","volume":"24 ","pages":"Pages 9-15"},"PeriodicalIF":5.2,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145398513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hematologic disease and chronic alcohol use independently predict poor prognosis in pyoderma gangrenosum","authors":"Yang Yang MD,&nbsp;Zhongrui Xu MD,&nbsp;Wenyao Chen MD,&nbsp;Jiao Ning MD,&nbsp;Xiaolei Su MD,&nbsp;Guangquan Xu MD,&nbsp;Mengjiao Li MD,&nbsp;Jiaqi Wang MD,&nbsp;Gang Wang MD, PhD,&nbsp;Shuai Shao MD, PhD","doi":"10.1016/j.jdin.2025.10.006","DOIUrl":"10.1016/j.jdin.2025.10.006","url":null,"abstract":"","PeriodicalId":34410,"journal":{"name":"JAAD International","volume":"24 ","pages":"Pages 169-171"},"PeriodicalIF":5.2,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145614352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neoadjuvant cemiplimab to facilitate Mohs micrographic surgery tumor extirpation and reduce surgical morbidity","authors":"Marianne Cortes DO ,&nbsp;Jorge O. Santana BA ,&nbsp;John Strasswimmer MD, PhD","doi":"10.1016/j.jdin.2025.09.014","DOIUrl":"10.1016/j.jdin.2025.09.014","url":null,"abstract":"","PeriodicalId":34410,"journal":{"name":"JAAD International","volume":"24 ","pages":"Pages 90-91"},"PeriodicalIF":5.2,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145520946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A network-based cross-sectional study of geographic access disparities to Medicare-participating dermatologists in the United States","authors":"Clayton Frazier MS ,&nbsp;Congcong Miao MS ,&nbsp;Sara Shalin MD, PhD ,&nbsp;Hanna Jensen MD, PhD ,&nbsp;Emily Frazier PhD","doi":"10.1016/j.jdin.2025.09.016","DOIUrl":"10.1016/j.jdin.2025.09.016","url":null,"abstract":"","PeriodicalId":34410,"journal":{"name":"JAAD International","volume":"24 ","pages":"Pages 70-72"},"PeriodicalIF":5.2,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145468582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Utilization and predictors of use of immunomodulators for atopic dermatitis: A cohort study","authors":"Priyanka Anand MD, MPH ,&nbsp;Arash Mostaghimi MD, MPA, MPH ,&nbsp;Robert Glynn PhD, ScD ,&nbsp;Yinzhu Jin MPH ,&nbsp;Joseph F. Merola MD, MMSc ,&nbsp;Jonathan I. Silverberg MD, PhD, MPH ,&nbsp;David M. Rosmarin MA, MD ,&nbsp;Robert Sidbury MD, MPH ,&nbsp;Joan Landon MPH ,&nbsp;Maria C. Schneeweiss MD","doi":"10.1016/j.jdin.2025.10.016","DOIUrl":"10.1016/j.jdin.2025.10.016","url":null,"abstract":"","PeriodicalId":34410,"journal":{"name":"JAAD International","volume":"24 ","pages":"Pages 259-262"},"PeriodicalIF":5.2,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145732993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High prevalence of orocutaneous features in Yemeni patients with tuberous sclerosis complex","authors":"Mohammad Ali Alshami MD ,&nbsp;Ahlam Mohamed Al-shami MSc ,&nbsp;Mona Jameel Mohana MD ,&nbsp;Amat Alkhaliq Mohammed Al-Sayaghi MSc ,&nbsp;Hadeel Mohammad Alshami MD","doi":"10.1016/j.jdin.2025.11.013","DOIUrl":"10.1016/j.jdin.2025.11.013","url":null,"abstract":"","PeriodicalId":34410,"journal":{"name":"JAAD International","volume":"24 ","pages":"Pages 294-295"},"PeriodicalIF":5.2,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145924382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dupilumab for bullous pemphigoid: Umbrella review of systematic reviews and meta-analyses","authors":"Mishek Thapa BS,&nbsp;Brianna Green BS,&nbsp;Michael Kasperkiewicz MD","doi":"10.1016/j.jdin.2025.10.004","DOIUrl":"10.1016/j.jdin.2025.10.004","url":null,"abstract":"","PeriodicalId":34410,"journal":{"name":"JAAD International","volume":"24 ","pages":"Pages 172-176"},"PeriodicalIF":5.2,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145615069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}