JAAD International最新文献

{"title":"Set targets, assess response, intervene early to achieve minimal disease activity in atopic dermatitis (STRIVE AD): A modified Delphi consensus project to optimize management of atopic dermatitis in the United Kingdom","authors":"Maria Angeliki Gkini MD, MSc, PhD ,&nbsp;Helen Alexander MD ,&nbsp;Maria Barfoot MSc ,&nbsp;Alberto Barea RN, BSc, MSc ,&nbsp;Paula E. Beattie MBBCh, BaO, BSc, MRCP, MD ,&nbsp;Firas C. Kreeshan MBBS, MSc, MRCP ,&nbsp;Deborah Moffitt BSc, MBBS, MRCP ,&nbsp;Padma Mohandas MRCP, MRCGP, MSc ,&nbsp;Andrew E. Pink BMed Sci (Hons), BMBS, PhD, MRCP ,&nbsp;Andrew Proctor BSc (Hons) ,&nbsp;Ann Sergeant MBChB ,&nbsp;Laura J. Savage PhD","doi":"10.1016/j.jdin.2025.11.028","DOIUrl":"10.1016/j.jdin.2025.11.028","url":null,"abstract":"<div><h3>Background</h3><div>Guidelines for the management and treatment of atopic dermatitis have been extensively published in Europe and globally, however these are not always relevant to the United Kingdom (UK) clinical setting.</div></div><div><h3>Objectives</h3><div>To develop consensus statements for the optimized management of adults and children with atopic dermatitis in the UK.</div></div><div><h3>Method</h3><div>Consensus statements were developed by an expert advisory panel following a targeted literature review, based on 5 topics (patient centric approach, assessing severity consistently, setting treatment targets, early intervention, and optimizing treatment). Consensus statements were voted on using a 5-point Likert scale in a Delphi over 3 rounds by 12 multidisciplinary, geographically spread participants. Consensus was reached if ≥75% of the voting participants rated the statement as 4 or 5.</div></div><div><h3>Results</h3><div>Strong consensus (≥90%) was achieved for 24 out of 27 statements. The level of consensus by topic was: Patient centric approach (92%-100%); Assessing severity consistently (75%-100%); Setting treatment targets (83%-100%); Intervening early (92%-100%); Optimizing treatment (92%).</div></div><div><h3>Limitations</h3><div>Due to the design and objectives of the study only a small number of participants were invited to take part.</div></div><div><h3>Conclusions</h3><div>The following recommendations have been developed to be practical and easy to implement within everyday clinical practice.</div></div>","PeriodicalId":34410,"journal":{"name":"JAAD International","volume":"25 ","pages":"Pages 56-68"},"PeriodicalIF":5.2,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146080314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"GLP-1 receptor agonist use in patients with psoriasis or hidradenitis suppurativa","authors":"Rachel Granovsky MSc, BA ,&nbsp;Allison Bai BA ,&nbsp;Ilona Ponyatyshyn BA ,&nbsp;Zhuoqing Suzy Gellatly MS, BA ,&nbsp;Jatin Narang MS, MD ,&nbsp;Gabriela Cobos MD","doi":"10.1016/j.jdin.2025.12.008","DOIUrl":"10.1016/j.jdin.2025.12.008","url":null,"abstract":"","PeriodicalId":34410,"journal":{"name":"JAAD International","volume":"25 ","pages":"Pages 8-10"},"PeriodicalIF":5.2,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146039513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adults with a history of melanoma have higher odds of laryngeal cancer in the United States","authors":"Aya Youssef BS ,&nbsp;Yeon Joo Kim MD, PhD ,&nbsp;Brandon Smith MD ,&nbsp;Joe K. Tung MD, MBA","doi":"10.1016/j.jdin.2025.12.006","DOIUrl":"10.1016/j.jdin.2025.12.006","url":null,"abstract":"","PeriodicalId":34410,"journal":{"name":"JAAD International","volume":"25 ","pages":"Pages 11-13"},"PeriodicalIF":5.2,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146039514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Deucravacitinib, an oral, selective, allosteric tyrosine kinase 2 (TYK2) inhibitor, in patients with moderate to severe scalp psoriasis: Efficacy and safety results through week 16 in a phase 3b/4, multicenter, randomized, double-blinded, placebo-controlled trial (PSORIATYK SCALP)","authors":"Kristina Callis Duffin MD, MS ,&nbsp;Christopher E.M. Griffiths MD, FMedSci ,&nbsp;Matthias Hoffmann MD ,&nbsp;Andrew Blauvelt MD, MBA ,&nbsp;Yevgeniy Balagula MD ,&nbsp;Andrew Napoli PhD ,&nbsp;Brandon Becker PhD, MPH ,&nbsp;Ying-Ming Jou PhD ,&nbsp;Rachel Dyme MD ,&nbsp;Virginia Hala BS ,&nbsp;Andreas Pinter MD ,&nbsp;Diamant Thaçi MD ,&nbsp;Linda Stein Gold MD ,&nbsp;Mark Lebwohl MD","doi":"10.1016/j.jdin.2025.09.022","DOIUrl":"10.1016/j.jdin.2025.09.022","url":null,"abstract":"<div><h3>Background</h3><div>Deucravacitinib, an oral, selective, allosteric tyrosine kinase 2 inhibitor, is approved in multiple countries for adults with moderate to severe plaque psoriasis who are candidates for systemic therapy.</div></div><div><h3>Objective</h3><div>The 52-week, phase 3b/4 PSORIATYK SCALP (NCT05478499) trial evaluated deucravacitinib efficacy and safety in scalp psoriasis, including patients with more limited overall psoriasis. Here, we report week 16 results.</div></div><div><h3>Methods</h3><div>Adults with moderate to severe scalp psoriasis and body surface area involvement ≥ 3% were randomized 1:2 to placebo (<em>n</em> = 51) or deucravacitinib 6 mg once daily (<em>n</em> = 103) through week 16. The primary efficacy endpoint was scalp-specific Physician Global Assessment score of 0/1; key secondary endpoints were Psoriasis Scalp Severity Index 90, scalp-specific numeric rating scale itch score, and static Physician Global Assessment (sPGA) 0/1.</div></div><div><h3>Results</h3><div>In the overall population, scalp-specific Physician Global Assessment score of 0/1 (48.5% vs 13.7%; <em>P</em> &lt; .0001), Psoriasis Scalp Severity Index 90 (38.8% vs 2.0%; <em>P</em> &lt; .0001), and mean change from baseline in scalp-specific numeric rating scale itch (−3.2 vs −0.7; <em>P</em> &lt; .0001) were superior with deucravacitinib versus placebo. In the sPGA ≥ 3 subpopulation, sPGA 0/1 was superior with deucravacitinib (51.0% vs 4.3%; <em>P</em> &lt; .0001). Adverse events were comparable between groups.</div></div><div><h3>Limitations</h3><div>16-week analysis.</div></div><div><h3>Conclusion</h3><div>Deucravacitinib was efficacious and well tolerated in patients with moderate to severe scalp psoriasis.</div></div>","PeriodicalId":34410,"journal":{"name":"JAAD International","volume":"25 ","pages":"Pages 28-40"},"PeriodicalIF":5.2,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146039515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Maternal vitiligo is associated with increased autoimmune and atopic disease in offspring: A nationwide birth cohort study","authors":"Hyun Jung Kim MPH, PhD ,&nbsp;Hei Sung Kim MD, PhD","doi":"10.1016/j.jdin.2025.12.011","DOIUrl":"10.1016/j.jdin.2025.12.011","url":null,"abstract":"","PeriodicalId":34410,"journal":{"name":"JAAD International","volume":"25 ","pages":"Pages 41-43"},"PeriodicalIF":5.2,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146039509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Infection and risk of psoriasis and atopic dermatitis: A systematic review and meta-analysis","authors":"Zhiru Zhou MD ,&nbsp;Xu Yao MD ,&nbsp;Juan Su MD ,&nbsp;Minxue Shen PhD ,&nbsp;Hervé Bachelez MD ,&nbsp;Xiang Chen MD ,&nbsp;Yi Xiao PhD","doi":"10.1016/j.jdin.2025.12.007","DOIUrl":"10.1016/j.jdin.2025.12.007","url":null,"abstract":"","PeriodicalId":34410,"journal":{"name":"JAAD International","volume":"25 ","pages":"Pages 14-15"},"PeriodicalIF":5.2,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146039504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interpreting the global burden of disease 2023 dermatology estimates: Best practices, caveats, and limitations for researchers and clinicians","authors":"Jonathan Yongwei Boey MRCP, MMED, MBBS ,&nbsp;Jonathan Kantor MD, MSc, MSCE ,&nbsp;Ellie Choi MRCP, MMED, MBBS","doi":"10.1016/j.jdin.2025.12.002","DOIUrl":"10.1016/j.jdin.2025.12.002","url":null,"abstract":"","PeriodicalId":34410,"journal":{"name":"JAAD International","volume":"25 ","pages":"Pages 78-80"},"PeriodicalIF":5.2,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146189829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Broad laboratory testing does not show utility for telogen effluvium: A retrospective analysis of 22-million laboratory results using TriNetX","authors":"Zachary J.K. Neubauer BS ,&nbsp;Shari R. Lipner MD, PhD","doi":"10.1016/j.jdin.2025.12.013","DOIUrl":"10.1016/j.jdin.2025.12.013","url":null,"abstract":"","PeriodicalId":34410,"journal":{"name":"JAAD International","volume":"25 ","pages":"Pages 81-83"},"PeriodicalIF":5.2,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146189830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Eye involvement in a series of 94 young patients with congenital ichthyosis: Importance of early ophthalmological referral","authors":"Natalia Blanco-Calvo MD ,&nbsp;Antonio Núñez-Reiz MD ,&nbsp;Isabel Vals-Ferrán MD ,&nbsp;Raman Malhotra MD ,&nbsp;Angela Hernández-Martín MD","doi":"10.1016/j.jdin.2025.12.004","DOIUrl":"10.1016/j.jdin.2025.12.004","url":null,"abstract":"","PeriodicalId":34410,"journal":{"name":"JAAD International","volume":"25 ","pages":"Pages 25-27"},"PeriodicalIF":5.2,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146039507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of scratches and mat hygiene in wrestling-associated skin infections","authors":"Talia Thomas BS ,&nbsp;Luke Moore BS, MBTS ,&nbsp;Angela Moore MD","doi":"10.1016/j.jdin.2025.11.030","DOIUrl":"10.1016/j.jdin.2025.11.030","url":null,"abstract":"","PeriodicalId":34410,"journal":{"name":"JAAD International","volume":"25 ","pages":"Pages 20-21"},"PeriodicalIF":5.2,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146039503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}