Michael Benzaquen MD , Simone Cazzaniga PhD , Franco Rongioletti MD , Elena Pezzolo MD , Giorgia Di Marco MD , Luigi Naldi MD , Luca Borradori MD
{"title":"Association of comorbidities and drug intake with generalized chronic pruritus: A multicenter case-control study in Switzerland and Italy","authors":"Michael Benzaquen MD , Simone Cazzaniga PhD , Franco Rongioletti MD , Elena Pezzolo MD , Giorgia Di Marco MD , Luigi Naldi MD , Luca Borradori MD","doi":"10.1016/j.jdin.2025.08.007","DOIUrl":"10.1016/j.jdin.2025.08.007","url":null,"abstract":"","PeriodicalId":34410,"journal":{"name":"JAAD International","volume":"23 ","pages":"Pages 61-63"},"PeriodicalIF":5.2,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145159134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ricardo da Silva Libório MD, Hélio Amante Miot MD, PhD, Paulo Müller Ramos MD, PhD
{"title":"Response to “Improvement of female pattern hair loss with bicalutamide: A time-dependent process”","authors":"Ricardo da Silva Libório MD, Hélio Amante Miot MD, PhD, Paulo Müller Ramos MD, PhD","doi":"10.1016/j.jdin.2025.08.006","DOIUrl":"10.1016/j.jdin.2025.08.006","url":null,"abstract":"","PeriodicalId":34410,"journal":{"name":"JAAD International","volume":"23 ","pages":"Page 45"},"PeriodicalIF":5.2,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145119543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yizhu Xiao PhD, Jingyi He PhD, Anwei Chen MD, Xiao Fang MD, Ping Tang MD, Juan Xiang PhD
{"title":"Management of childhood granulomatous periorificial dermatitis with clarithromycin: A retrospective cohort study","authors":"Yizhu Xiao PhD, Jingyi He PhD, Anwei Chen MD, Xiao Fang MD, Ping Tang MD, Juan Xiang PhD","doi":"10.1016/j.jdin.2025.08.005","DOIUrl":"10.1016/j.jdin.2025.08.005","url":null,"abstract":"<div><h3>Background</h3><div>Childhood granulomatous periorificial dermatitis incidence is increasing, yet topical therapies remain suboptimal with chronicity and scarring risks in severe cases. Systemic alternatives are urgently needed. Although oral clarithromycin shows promise, its efficacy/safety evidence in pediatric populations lacks robustness.</div></div><div><h3>Objective</h3><div>This study evaluated the effect of clarithromycin on a pediatric group with granulomatous periorificial dermatitis.</div></div><div><h3>Methods</h3><div>This retrospective study analyzed 43 patients treated with oral clarithromycin, with outcomes including treatment efficacy, adverse event incidence, and scar incidence.</div></div><div><h3>Results</h3><div>All patients completed clarithromycin therapy (median 10 weeks; 2-26). At 6 months, 95.4% (41/43) cleared, with 2.3% each recurrence and nonresponse. Treatment duration correlated with both baseline severity (<em>r</em> = 0.592, <em>P</em> < .01) and disease duration (<em>r</em> = 0.590, <em>P</em> < .01). Scarring (14.6%) occurred only in moderate-to-severe cases, which showed greater severity (<em>P</em> = .039) and longer courses (<em>P</em> = .028). No severe adverse events occurred.</div></div><div><h3>Limitations</h3><div>This is a retrospective study without case controls and is subject to interviewer and memory bias.</div></div><div><h3>Conclusion</h3><div>For moderate-to-severe or stubborn cases, timely evaluation and tailored systemic interventions are critical to mitigate scarring risks. Clarithromycin is an effective and tolerated therapy in children with moderate-to-severe and refractory granulomatous periorificial dermatitis.</div></div>","PeriodicalId":34410,"journal":{"name":"JAAD International","volume":"23 ","pages":"Pages 48-54"},"PeriodicalIF":5.2,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145159133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Knowledge and awareness about the harmful effects of sun exposure on the skin and sun safety methods used in the adult Kuwaiti population: A questionnaire-based study","authors":"Rawan Almutairi MD, Atlal Allafi MD","doi":"10.1016/j.jdin.2025.05.021","DOIUrl":"10.1016/j.jdin.2025.05.021","url":null,"abstract":"<div><h3>Background</h3><div>Sun exposure can have both positive and negative effects on human health.</div></div><div><h3>Objective</h3><div>This study aimed to evaluate the awareness level about sun harmful effects on the skin of adult Kuwaitis and to study their attitudes and practices of using sun-protective methods.</div></div><div><h3>Methods</h3><div>Observational multicentric questionnaire study was conducted on patients who visited primary health care centers in Kuwait. Data were collected from 2023 to 2024. The sample included only Kuwaiti adults aged 18 and older.</div></div><div><h3>Results</h3><div>723 individuals participated in this study. The mean age was 36 years. Two-thirds of the participants were females. Almost two-thirds of respondents were both mindful of the association between sun exposure and skin aging and pigmentation, while minority reported no side effects. Thirty-nine percent of respondents were aware of the association between skin cancer and solar exposure. Females and lighter skin type demonstrated a higher level of using sunscreens. Only 27% of the participants were using sunscreens regularly and almost half of those who did not use it stated that it is not important to apply sunscreen.</div></div><div><h3>Conclusion</h3><div>Kuwaiti adults possessed a satisfactory awareness level regarding sun adverse effects. The utilization of sunscreen was inadequate, regardless of their awareness and education.</div></div>","PeriodicalId":34410,"journal":{"name":"JAAD International","volume":"23 ","pages":"Pages 38-44"},"PeriodicalIF":5.2,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145097948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}