JAAD International最新文献_第10页

Evaluating the psychosocial burden and unmet needs for health care access among older adults with inflammatory skin disease 评估老年炎症性皮肤病患者的心理社会负担和未满足的卫生保健需求。

JAAD International Pub Date : 2025-02-01 DOI: 10.1016/j.jdin.2024.11.006

Alyssa M. Roberts BS , Danielle West BS , Benjamin Stroebel MPH , Katrina Abuabara MD, MA, MSCE

引用次数: 0

Skin manifestations and related clinical characteristics of multisystem inflammatory syndrome in children: A descriptive retrospective cohort study at Texas Children’s Hospital 儿童多系统炎症综合征的皮肤表现和相关临床特征：德克萨斯儿童医院的一项描述性回顾性队列研究

JAAD International Pub Date : 2025-02-01 DOI: 10.1016/j.jdin.2024.09.009

Matthew Penna MD, PhD , Lauren Pupa MD , Grace Lee MD , Soo Jung Kim MD, PhD

{"title":"Skin manifestations and related clinical characteristics of multisystem inflammatory syndrome in children: A descriptive retrospective cohort study at Texas Children’s Hospital","authors":"Matthew Penna MD, PhD , Lauren Pupa MD , Grace Lee MD , Soo Jung Kim MD, PhD","doi":"10.1016/j.jdin.2024.09.009","DOIUrl":"10.1016/j.jdin.2024.09.009","url":null,"abstract":"<div><h3>Background</h3><div>Little is known about the dermatologic manifestations of multisystem inflammatory syndrome in children (MIS-C) in children and adolescents.</div></div><div><h3>Objective</h3><div>We sought to describe the demographic background, key clinical features, and the clinical consequences of developing rash manifestations in MIS-C patients at Texas Children’s Hospital.</div></div><div><h3>Methods</h3><div>Descriptive retrospective cohort study of 290 hospitalized eligible patients between May 2020 and April 2022.</div></div><div><h3>Results</h3><div>Among MIS-C patients, 51% exhibited a rash. We found that younger children (8.62 vs 9.49 years of age, <em>P</em> = .006) and White children (<em>P</em> = .002) had a higher likelihood of developing a rash in association with MIS-C. Additionally, patients without a rash had increased maximum troponin levels (0.11 ng/mL vs 0.07 ng/mL, <em>P</em> = .02) and a higher incidence of cardiac involvement (83.1% vs 72.3%, <em>P</em> = .03) compared to those with a rash but did not significantly affect the length of hospital stay or clinical course. The most commonly observed rash was an erythematous and maculopapular rash on the trunk and/or extremities.</div></div><div><h3>Limitations</h3><div>Rash characteristics were initially described by a variety of physicians in the pediatric primary care services.</div></div><div><h3>Conclusion</h3><div>Rash manifestations in MIS-C patients are associated with lower cardiac involvement and decreased troponin levels.</div></div>","PeriodicalId":34410,"journal":{"name":"JAAD International","volume":"18 ","pages":"Pages 122-127"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11667042/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142885390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Atopic dermatitis increases the risk of infective endocarditis in prosthetic heart valve patients – A retrospective study 特应性皮炎增加人工心脏瓣膜患者感染性心内膜炎的风险-一项回顾性研究。

JAAD International Pub Date : 2025-02-01 DOI: 10.1016/j.jdin.2024.09.016

Chapman Wei MD , Ahmad Mustafa MD , Radu Grovu MD , Angela Rosenberg DO , Alaukika Agarwal MD , Alanna Davis MD , Nawal Mustafa MD , Stefan Bradu MD , Suzanne El-Sayegh MD

引用次数: 0

Heterogeneity among melanoma databases and challenges in sustainability: A survey of the Melanoma Prevention Working Group 黑色素瘤数据库的异质性和可持续性挑战：黑色素瘤预防工作组调查

JAAD International Pub Date : 2025-02-01 DOI: 10.1016/j.jdin.2024.02.001

Sheyda Mesgarzadeh BS , Caitlyn N. Myrdal MD , Amanda H. Gong BS , Delaney B. Stratton PhD, DNP, FNP-BC , Brenna G. Kelly MD , Clara Curiel-Lewandrowski MD

引用次数: 0

Comorbidities in hidradenitis suppurativa: Role of metabolic syndrome and sexual dysfunction disorders in postoperative healing 化脓性汗腺炎的合并症：代谢综合征和性功能障碍在术后愈合中的作用。

JAAD International Pub Date : 2025-02-01 DOI: 10.1016/j.jdin.2024.09.006

Sowmya Ravi MPH , Tatjana Mortell BS , Dylan Wolff MD , Amy Stein PhD , Emily Coleman MD , Abigail Chaffin MD, CWSP, MAPWCA

引用次数: 0

The impact of academic stress on acne: An observational cohort study among medical students in Morocco 学业压力对痤疮的影响：摩洛哥医学生的观察性队列研究。

JAAD International Pub Date : 2025-02-01 DOI: 10.1016/j.jdin.2024.09.019

Oumaima Bouraqqadi MD , Meryem Soughi MD , Moncef Maiouak MD , Zakia Douhi MD , Sara Elloudi MD , Hanane BayBay MD , Fatima Zahra Mernissi MD

引用次数: 0

Impact of disease cyclicity on quality-of-life impairment—A mixed method explanatory study 疾病循环对生活质量损害的影响——一项混合方法解释性研究。

JAAD International Pub Date : 2025-02-01 DOI: 10.1016/j.jdin.2024.09.007

Ying Shan Cheung MD , Winston Tham Zhi Wen , Ashvin R. Chundayil , Phillip Phan PhD , Ellie Choi Ci-En MBBS, MRCP

{"title":"Impact of disease cyclicity on quality-of-life impairment—A mixed method explanatory study","authors":"Ying Shan Cheung MD , Winston Tham Zhi Wen , Ashvin R. Chundayil , Phillip Phan PhD , Ellie Choi Ci-En MBBS, MRCP","doi":"10.1016/j.jdin.2024.09.007","DOIUrl":"10.1016/j.jdin.2024.09.007","url":null,"abstract":"<div><h3>Background</h3><div>Disease cyclicity, a composite measure of unpredictable and daily fluctuations of symptoms, strongly predicts quality-of-life (QoL) impairment.</div></div><div><h3>Objective</h3><div>To explore the mechanisms by which cyclicity impacts QoL.</div></div><div><h3>Methods</h3><div>1:1 semi-structured interviews were conducted and qualitatively analyzed using grounded theory. Common themes were identified and used to derive a theoretical framework.</div></div><div><h3>Results</h3><div>Twenty-three adults, (median age 28.5, range 20-72) with a range of chronic inflammatory diseases including eczema, psoriasis, and inflammatory arthritis were prospectively recruited. Cyclicity, characterized by unpredictability, uncontrollability, and lability, contributed to a varying productivity and inconsistent ability in performing daily activities. Challenges intensified if external expectations of the patient were inconsistent with their fluctuating ability. Coping abilities, shaped by internal and external factors, moderated the relationship between cyclicity and QoL impairment.</div></div><div><h3>Limitations</h3><div>Qualitative interviews assume patients have accurate insights into their own behaviors. The generalizability of findings may be limited in other populations.</div></div><div><h3>Conclusion</h3><div>Disease cyclicity defines many inflammatory diseases. This study provides a theoretical framework for understanding and managing the challenges patients with a cyclical condition face.</div></div>","PeriodicalId":34410,"journal":{"name":"JAAD International","volume":"18 ","pages":"Pages 180-187"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11751501/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143025021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Risk of infections during treatment with oral Janus kinase inhibitors in randomized placebo-controlled trials: A systematic review and meta-analysis 随机安慰剂对照试验中口服Janus激酶抑制剂治疗期间感染的风险：系统回顾和荟萃分析。

JAAD International Pub Date : 2025-02-01 DOI: 10.1016/j.jdin.2024.09.012

Daniel Isufi BSc(Med) , Mikkel Bak Jensen MD , Nikolai Loft MD, PhD , Lone Skov MD, PhD, DMSc , Jesper Elberling MD, PhD , Farzad Alinaghi MD, PhD

{"title":"Risk of infections during treatment with oral Janus kinase inhibitors in randomized placebo-controlled trials: A systematic review and meta-analysis","authors":"Daniel Isufi BSc(Med) , Mikkel Bak Jensen MD , Nikolai Loft MD, PhD , Lone Skov MD, PhD, DMSc , Jesper Elberling MD, PhD , Farzad Alinaghi MD, PhD","doi":"10.1016/j.jdin.2024.09.012","DOIUrl":"10.1016/j.jdin.2024.09.012","url":null,"abstract":"<div><div>Janus kinase (JAK) inhibitors block pathways involved in inflammation and immune response, making JAK inhibitors useful in the treatment of various diseases. While the efficacy of these drugs has been proven in several studies, their safety profile needs to be further investigated. In this systematic review and meta-analysis, we examined the risk of infections during treatment with oral JAK inhibitors with no concomitant treatment compared to placebo in phase 2 and 3 randomized, placebo-controlled trials. The medical databases PubMed, Web of Science, and EMBASE were searched from inception through February 2024, yielding 13,567 nonduplicate articles, of which 69 were included in the final quantitative analysis. Overall, we found that treatment with oral JAK inhibitors was associated with an increased risk of infections compared to placebo across all indications (relative risk: 1.39 [95% CI: 1.096-1.76, <em>P</em> = .0067]) and in dermatologic indications (relative risk: 1.46 [95% CI, 1.10-1.93, <em>P</em> = .0097]). Remarkably, an increased risk of herpes zoster infections was found in dermatologic indications but not in nondermatologic indications. In conclusion, we identified a significantly increased risk of developing infections during treatment with oral JAK inhibitors compared to placebo across indications. In sub-analyses, we additionally found an increased risk of herpes zoster in dermatologic indications.</div></div>","PeriodicalId":34410,"journal":{"name":"JAAD International","volume":"18 ","pages":"Pages 106-116"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11664075/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142883106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluating the appropriateness of skin cancer prevention recommendations obtained from an online chat-based artificial intelligence model 评估从基于在线聊天的人工智能模型获得的皮肤癌预防建议的适当性。

JAAD International Pub Date : 2025-02-01 DOI: 10.1016/j.jdin.2024.07.028

Elise M. Cai BS, Pirunthan Pathmarajah MD, Roxana Daneshjou MD, PhD, Justin M. Ko MD, MBA, Albert S. Chiou MD, MBA

引用次数: 0

NRAS tumor mutations are associated with reduced odds of dermatologic adverse events in patients with metastatic melanoma receiving immune checkpoint inhibitors 在接受免疫检查点抑制剂治疗的转移性黑色素瘤患者中，NRAS肿瘤突变与皮肤不良事件发生率降低相关。

JAAD International Pub Date : 2025-02-01 DOI: 10.1016/j.jdin.2024.11.004

Michael S. Chang MD , Jordan T. Said MD , Elliot H. Akama-Garren PhD , Nicole Trepanowski MD , Ai-Tram N. Bui MD , Anita Giobbie-Hurder MS , Nicole R. LeBoeuf MD, MPH , Rebecca I. Hartman MD, MPH

引用次数: 0