Yu-Chen Jeng MD, Julia Yu-Yun Lee MD, Wei-Ting Liu MD
{"title":"Peel-and-Swiss roll biopsy: A practical technique for tissue sampling in fragile blistering skin conditions","authors":"Yu-Chen Jeng MD, Julia Yu-Yun Lee MD, Wei-Ting Liu MD","doi":"10.1016/j.jdin.2025.08.001","DOIUrl":"10.1016/j.jdin.2025.08.001","url":null,"abstract":"","PeriodicalId":34410,"journal":{"name":"JAAD International","volume":"23 ","pages":"Pages 12-13"},"PeriodicalIF":5.2,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145044690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Debby Cheng BA , Nga Thi Thanh Nguyen MD, MPH , Christopher J. Thang BS , Olivia Marie Burke BS , Nicole R. LeBoeuf MD, MPH , Nicholas Theodosakis MD, PhD , Yevgeniy R. Semenov MD, MA
{"title":"Exposure to intravenous immunoglobulin is associated with increased mortality in patients on immune checkpoint inhibitors: A population-based cohort study","authors":"Debby Cheng BA , Nga Thi Thanh Nguyen MD, MPH , Christopher J. Thang BS , Olivia Marie Burke BS , Nicole R. LeBoeuf MD, MPH , Nicholas Theodosakis MD, PhD , Yevgeniy R. Semenov MD, MA","doi":"10.1016/j.jdin.2025.07.006","DOIUrl":"10.1016/j.jdin.2025.07.006","url":null,"abstract":"","PeriodicalId":34410,"journal":{"name":"JAAD International","volume":"23 ","pages":"Pages 17-19"},"PeriodicalIF":5.2,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145048642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Matthew J. Yan BS, BA , Peichi P. Chou BA , Alyssa M. Roberts BS , Charlotte Y. Jeong BS , Nicole Johnsen BS , Abigail Katz BA , Elaine J. Ma BA , Yvonne Nong MD , April W. Armstrong MD, MPH
{"title":"Variation in depression risk by race and ethnicity in vitiligo","authors":"Matthew J. Yan BS, BA , Peichi P. Chou BA , Alyssa M. Roberts BS , Charlotte Y. Jeong BS , Nicole Johnsen BS , Abigail Katz BA , Elaine J. Ma BA , Yvonne Nong MD , April W. Armstrong MD, MPH","doi":"10.1016/j.jdin.2025.07.005","DOIUrl":"10.1016/j.jdin.2025.07.005","url":null,"abstract":"","PeriodicalId":34410,"journal":{"name":"JAAD International","volume":"23 ","pages":"Pages 20-23"},"PeriodicalIF":5.2,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145097949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jamie L. Karch MD , Katherine E. Bradley BA , Angel M. Moore BSc , Mirjana Stevanovic BSc , Iman Salem MD , Brian J. Simmons MD
{"title":"A retrospective study on the demographics and epidemiology of pyoderma gangrenosum: Insights from a single-center analysis","authors":"Jamie L. Karch MD , Katherine E. Bradley BA , Angel M. Moore BSc , Mirjana Stevanovic BSc , Iman Salem MD , Brian J. Simmons MD","doi":"10.1016/j.jdin.2025.04.009","DOIUrl":"10.1016/j.jdin.2025.04.009","url":null,"abstract":"","PeriodicalId":34410,"journal":{"name":"JAAD International","volume":"21 ","pages":"Pages 58-60"},"PeriodicalIF":5.2,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144660523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sheyda Mesgarzadeh BS , Rosemond S. Amamoo MD, MPH , Geethika Ameneni BS , Amanda H. Gong BS , Oluwayemisi O. Ayoade MD, MPH , Delaney B. Stratton PhD, DNP , Emile Latour PhD, MPH , Wesley Yu MD , Clara Curiel-Lewandrowski MD , Ivo Abraham PhD , Mohammad Fazel MD, PharmD
{"title":"Validation of risk prediction models for sentinel lymph node metastasis in melanoma in a high UV index region","authors":"Sheyda Mesgarzadeh BS , Rosemond S. Amamoo MD, MPH , Geethika Ameneni BS , Amanda H. Gong BS , Oluwayemisi O. Ayoade MD, MPH , Delaney B. Stratton PhD, DNP , Emile Latour PhD, MPH , Wesley Yu MD , Clara Curiel-Lewandrowski MD , Ivo Abraham PhD , Mohammad Fazel MD, PharmD","doi":"10.1016/j.jdin.2025.04.012","DOIUrl":"10.1016/j.jdin.2025.04.012","url":null,"abstract":"<div><h3>Background</h3><div>Risk prediction models may refine individualized selection for sentinel lymph node biopsy (SLNB) in melanoma.</div></div><div><h3>Objective</h3><div>To evaluate the statistical accuracy and clinical utility of nomograms by the Melanoma Institute of Australia (MIA), Memorial Sloan Kettering Cancer Center (MSKCC), and University of Colorado in a Southern Arizona population.</div></div><div><h3>Methods</h3><div>In this prognostic validation, statistical accuracy was assessed through discrimination, measured with receiver operating characteristic curves and calibration plots. Clinical utility was evaluated via decision curve analysis to determine the net benefit and number of net avoidable interventions achieved with nomogram use.</div></div><div><h3>Results</h3><div>Among 712 melanoma cases included, model discrimination was highest for the MIA nomogram (C-statistic = 0.753; 95% confidence interval = 0.694-0.812), followed by MSKCC (0.729[0.671-0.787]), and University of Colorado (0.601[0.405-0.793]). The MIA and MSKCC nomograms were well-calibrated across clinically relevant risk thresholds. All nomograms achieved a net benefit and net reduction in avoidable SLNBs for risk thresholds ≥5%. There was minimal to no reduction in unnecessary interventions at age extremes (<50 and ≥ 80 years old) for specific risk strata and nomograms.</div></div><div><h3>Limitations</h3><div>This a 5-year retrospective study.</div></div><div><h3>Conclusions</h3><div>These nomograms can be used to support SLNB decision-making in this population but necessitate caution in patients at age extremes when used to reduce avoidable interventions.</div></div>","PeriodicalId":34410,"journal":{"name":"JAAD International","volume":"21 ","pages":"Pages 61-69"},"PeriodicalIF":5.2,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144660525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mehdi Boostani MD , Giovanni Pellacani MD, PhD , Ximena Wortsman MD , Mariano Suppa MD, PhD , Mohamad Goldust MD , Carmen Cantisani MD, PhD , Paweł Pietkiewicz MD, PhD , Kende Lőrincz MD, PhD , András Bánvölgyi MD, PhD , Norbert M. Wikonkál MD, PhD , Wendy J. Huss PhD , Kamran Avanaki MS, PhD , Gyorgy Paragh MD, PhD , Norbert Kiss MD, PhD
{"title":"FDA and EMA-approved noninvasive imaging techniques for basal cell carcinoma subtyping: A systematic review","authors":"Mehdi Boostani MD , Giovanni Pellacani MD, PhD , Ximena Wortsman MD , Mariano Suppa MD, PhD , Mohamad Goldust MD , Carmen Cantisani MD, PhD , Paweł Pietkiewicz MD, PhD , Kende Lőrincz MD, PhD , András Bánvölgyi MD, PhD , Norbert M. Wikonkál MD, PhD , Wendy J. Huss PhD , Kamran Avanaki MS, PhD , Gyorgy Paragh MD, PhD , Norbert Kiss MD, PhD","doi":"10.1016/j.jdin.2025.05.006","DOIUrl":"10.1016/j.jdin.2025.05.006","url":null,"abstract":"<div><h3>Background</h3><div>Basal cell carcinoma (BCC), the most common skin cancer, requires accurate subtyping for optimal treatment. While histopathology is the gold standard, noninvasive imaging offers a biopsy-free alternative, though its accuracy remains unclear.</div></div><div><h3>Objective</h3><div>To assess the diagnostic accuracy of Food and Drug Administration- and European Medicines Agency-approved noninvasive imaging techniques for BCC subtyping.</div></div><div><h3>Methods</h3><div>A systematic review included 19 studies (2650 lesions) from EMBASE, Scopus, PubMed, and Cochrane Library (published up to November 30, 2024). Evaluated modalities included dermoscopy, high-frequency ultrasound (HFUS), dermoscopy-guided HFUS (DG-HFUS), optical coherence tomography (OCT), high-definition OCT (HD-OCT), dynamic OCT (D-OCT), line-field confocal OCT (LC-OCT), and reflectance confocal microscopy.</div></div><div><h3>Results</h3><div>Dermoscopy showed moderate accuracy (81.9% sensitivity, 81.8% specificity for superficial BCC [sBCC]). DG-HFUS outperformed HFUS (82.4% sensitivity, 91.3% specificity). LC-OCT had the highest accuracy, achieving 100% sensitivity for infiltrative BCC. D-OCT distinguished subtypes at 150 μm depth; branching vessels at 300 μm increased nBCC risk (relative risk = 1.53, <em>P</em> = .016). HD-OCT had 100% sensitivity for sBCC but lower accuracy for other subtypes. Reflectance confocal microscopy had 88.9% sensitivity for non-sBCC but only 33.3% for aggressive subtypes.</div></div><div><h3>Limitations</h3><div>Study heterogeneity and inconsistent protocols limit comparability.</div></div><div><h3>Conclusion</h3><div>LC-OCT and HD-OCT offer the highest accuracy, while DG-HFUS outperforms dermoscopy and HFUS, making them strong noninvasive alternatives.</div></div>","PeriodicalId":34410,"journal":{"name":"JAAD International","volume":"21 ","pages":"Pages 73-86"},"PeriodicalIF":5.2,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144675950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}