Luzheng Liu MD, PhD , Huy Tran MS , Ashley J. Mulford MS , Zhuqing Shi PhD , Jun Wei PhD , Annabelle Ashworth BA , S. Lilly Zheng MD , Jason B. Waldinger MD , Ross M. Levy MD , Alan R. Sanders MD , Jianfeng Xu MD, Dr PH
{"title":"Superior performance of two combined polygenic scores for predicting skin cancer risk and differentiating risk of melanoma from keratinocyte carcinomas in two cohorts","authors":"Luzheng Liu MD, PhD , Huy Tran MS , Ashley J. Mulford MS , Zhuqing Shi PhD , Jun Wei PhD , Annabelle Ashworth BA , S. Lilly Zheng MD , Jason B. Waldinger MD , Ross M. Levy MD , Alan R. Sanders MD , Jianfeng Xu MD, Dr PH","doi":"10.1016/j.jdin.2025.03.004","DOIUrl":"10.1016/j.jdin.2025.03.004","url":null,"abstract":"","PeriodicalId":34410,"journal":{"name":"JAAD International","volume":"21 ","pages":"Pages 70-72"},"PeriodicalIF":5.2,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144675951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Dermatoscopic markers of disease activity in vitiligo","authors":"Saâdia Boughaleb MD , Meryem Soughi MD , Ghita Sqalli MD , Aida Oulehri MD , Marwa El Baldi MD , Zakia Douhi MD , Sara Elloudi MD , Hanane Baybay MD , Karima El Rhazi MD , Fatima Zahra Mernissi MD","doi":"10.1016/j.jdin.2025.04.017","DOIUrl":"10.1016/j.jdin.2025.04.017","url":null,"abstract":"<div><h3>Background</h3><div>Determining vitiligo activity is essential for prognosis and treatment planning.</div></div><div><h3>Objectives</h3><div>To describe the dermoscopic findings and correlate them with the activity of the disease.</div></div><div><h3>Methods</h3><div>A single-center, descriptive, analytical study included 233 patients (330 lesions). Lesions were categorized as progressing, repigmenting, stable, or recent. Dermoscopic analysis was performed using a DermLite 4 dermatoscope, with statistical testing through Pearson’s chi-square.</div></div><div><h3>Results</h3><div>Progressing lesions were associated with trichrome pattern, reverse network, nacreous white globules, starburst, comet-tail pattern, micro-Koebner phenomenon, residual peripilar pigmentation with leukotrichia, perilesional polka dots, perifollicular depigmentation, and reverse network (<em>P</em> < .01). Stability was indicated by sharp borders (<em>P</em> < .01). Repigmenting lesions exhibited perifollicular or border hyperpigmentation, erythema, and telangiectasias (<em>P</em> < .01). Early vitiligo was suggested by hypopigmented lesions with attenuated network or perifollicular depigmentation (<em>P</em> < .01). Newly identified markers included distally pigmented bicolored hair for recent lesions and proximally pigmented bicolored hair for repigmentation.</div></div><div><h3>Limitations</h3><div>Most patients had prior treatment, potentially influencing dermoscopic patterns.</div></div><div><h3>Conclusion</h3><div>This study, based on a large sample size, identifies specific dermoscopic markers for vitiligo activity and introduces novel findings like bicolored hairs. These insights can refine clinical assessment and serve as a foundation for future research.</div></div>","PeriodicalId":34410,"journal":{"name":"JAAD International","volume":"23 ","pages":"Pages 29-37"},"PeriodicalIF":5.2,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145098024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lauren M. Ching BS , Christopher A. Guirguis DMD , Nicholas L. Iskandar , Joe K. Tung MD, MBA
{"title":"Decreased incidence of hidradenitis suppurativa and psoriasis in diabetic patients treated with GLP-1 receptor agonists: A retrospective cohort study","authors":"Lauren M. Ching BS , Christopher A. Guirguis DMD , Nicholas L. Iskandar , Joe K. Tung MD, MBA","doi":"10.1016/j.jdin.2025.07.003","DOIUrl":"10.1016/j.jdin.2025.07.003","url":null,"abstract":"","PeriodicalId":34410,"journal":{"name":"JAAD International","volume":"22 ","pages":"Pages 97-99"},"PeriodicalIF":5.2,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144879241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Youyou Jin MSc , Wei Hua MD , Qingfeng Liu MM , Zili Zheng EngD , Xinyi Yao MSc , Xiangling Zhang MSc , Mei Li MM , Xiaoyun Zhang BS , Ran Gao BS , Xiaoyu Wang BS , Yueyi Sun BS , Li Li MD , Wei Zhang MD , Chengchen Guo EngD , Yu Zhao MD , Haotian Liu MD
{"title":"Otitis externa due to allergic contact dermatitis to earphones and earplugs: A case control study","authors":"Youyou Jin MSc , Wei Hua MD , Qingfeng Liu MM , Zili Zheng EngD , Xinyi Yao MSc , Xiangling Zhang MSc , Mei Li MM , Xiaoyun Zhang BS , Ran Gao BS , Xiaoyu Wang BS , Yueyi Sun BS , Li Li MD , Wei Zhang MD , Chengchen Guo EngD , Yu Zhao MD , Haotian Liu MD","doi":"10.1016/j.jdin.2025.05.020","DOIUrl":"10.1016/j.jdin.2025.05.020","url":null,"abstract":"","PeriodicalId":34410,"journal":{"name":"JAAD International","volume":"23 ","pages":"Pages 1-3"},"PeriodicalIF":5.2,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145048511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"When topicals fall short, oral Janus kinase inhibitors offer a needed solution in chronic hand eczema","authors":"Christopher G. Bunick MD, PhD","doi":"10.1016/j.jdin.2025.06.007","DOIUrl":"10.1016/j.jdin.2025.06.007","url":null,"abstract":"","PeriodicalId":34410,"journal":{"name":"JAAD International","volume":"22 ","pages":"Pages 86-87"},"PeriodicalIF":5.2,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144809509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sera Sarsam MBBS, BMedSc , Ailin He , Dédée F. Murrell MA, BMBCh, MD (UNSW), DSc
{"title":"Ofatumumab for the management of refractory pemphigus vulgaris: A case series","authors":"Sera Sarsam MBBS, BMedSc , Ailin He , Dédée F. Murrell MA, BMBCh, MD (UNSW), DSc","doi":"10.1016/j.jdin.2025.05.018","DOIUrl":"10.1016/j.jdin.2025.05.018","url":null,"abstract":"","PeriodicalId":34410,"journal":{"name":"JAAD International","volume":"22 ","pages":"Pages 94-96"},"PeriodicalIF":5.2,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144879240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chico J. Collie MBBS, DM , Simone L. Jean-Marie MBBS , Rory K. Thompson MBBS, DM , Nadia P. Williams MBBS, DM , Jonathan D. Ho MBBS, D.Sc, Dip.Dermpath
{"title":"Acral lentiginous melanoma demonstrates more aggressive pathological features than non-acral melanoma in Jamaica: A 10-year multicenter study","authors":"Chico J. Collie MBBS, DM , Simone L. Jean-Marie MBBS , Rory K. Thompson MBBS, DM , Nadia P. Williams MBBS, DM , Jonathan D. Ho MBBS, D.Sc, Dip.Dermpath","doi":"10.1016/j.jdin.2025.06.005","DOIUrl":"10.1016/j.jdin.2025.06.005","url":null,"abstract":"","PeriodicalId":34410,"journal":{"name":"JAAD International","volume":"22 ","pages":"Pages 91-93"},"PeriodicalIF":5.2,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144810339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jalal Maghfour MD , John Meisenheimer MD , Jonathan Kantor MD, MSc, MSCE
{"title":"Cosmetic and functional outcomes of excisional surgical wounds healed by secondary intention: A systematic review","authors":"Jalal Maghfour MD , John Meisenheimer MD , Jonathan Kantor MD, MSc, MSCE","doi":"10.1016/j.jdin.2025.05.016","DOIUrl":"10.1016/j.jdin.2025.05.016","url":null,"abstract":"<div><h3>Background</h3><div>Data regarding short-term and long-term cosmesis and functional outcomes of excisional surgical wounds healed by secondary intention healing (SIH) are limited.</div></div><div><h3>Objective</h3><div>To conduct a systematic review and assess the cosmetic and functional acceptability of SIH for acute excisional surgical wounds.</div></div><div><h3>Methods</h3><div>Full-text articles queried from PubMed and Embase databases between January 1964 and April 2024 with cosmetic outcome data of human subjects with acute surgical wounds healed by SIH were included. Preferred Reporting Items for Systematic reviews and Meta-Analyses guidelines were followed.</div></div><div><h3>Results</h3><div>A total of 1655 surgical wounds, of which 1518 (91.7%) healed by SIH, from 35 studies, were included in this review. The most frequent indication for SIH was a defect resulting from excision of nonmelanoma skin cancer (keratinocyte carcinoma), which was identified in 1439 (86%) of patients. Common sites for SIH included the nose (23.3%), periocular region (15.46%), and forehead (13.5%). The majority of wounds on the forehead, medial canthus, lower eyelid, nasal ala, cheeks, lips, postauricular area, and feet resulted in good to excellent cosmetic results, whereas those on the scalp, nasal dorsum, nasal tip, nasal sidewall, and chin yielded less acceptable cosmetic results. Given the baseline variability in cosmesis of primarily closed wounds in some anatomic locations, however, these data suggest the need for future prospective studies.</div></div><div><h3>Summary</h3><div>SIH may produce an acceptable cosmetic and functional outcome for selected defects and may be of clinical benefit in the appropriate setting. This must be weighed against the potentially improved cosmesis and more rapid healing seen with primarily closed defects.</div></div>","PeriodicalId":34410,"journal":{"name":"JAAD International","volume":"22 ","pages":"Pages 100-110"},"PeriodicalIF":5.2,"publicationDate":"2025-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144916525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}