FS ReportsPub Date : 2025-04-01DOI: 10.1016/j.xfre.2025.01.004
Mayako Fujihara Ph.D. , Pierre Comizzoli D.V.M., Ph.D.
{"title":"Human and wildlife biobanks of germplasms and reproductive tissues can contribute to a broader concept of One Health","authors":"Mayako Fujihara Ph.D. , Pierre Comizzoli D.V.M., Ph.D.","doi":"10.1016/j.xfre.2025.01.004","DOIUrl":"10.1016/j.xfre.2025.01.004","url":null,"abstract":"<div><div>Biobanks are large collections of frozen biological samples (including reproductive tissues, gametes, and embryos) and their associated metadata that are stored for the long term. In addition to fundamental research and medical or veterinary applications, both human and wildlife biobanks support efforts in the study of reproductive biology and the development of reproductive biotechnologies. The objective of this review is to highlight cross-disciplinary interests and strategies for more synergy between human and wildlife biobanks, starting from optimal storage of germplasms and reproductive tissues to the opportunity to create a broader and more impactful concept of One Health.</div></div>","PeriodicalId":34409,"journal":{"name":"FS Reports","volume":"6 ","pages":"Pages 63-66"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143829707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
FS ReportsPub Date : 2025-03-01DOI: 10.1016/j.xfre.2025.02.006
Alan S. Penzias M.D.
{"title":"Access to care requires access to the ovaries: When ultrasound is not enough","authors":"Alan S. Penzias M.D.","doi":"10.1016/j.xfre.2025.02.006","DOIUrl":"10.1016/j.xfre.2025.02.006","url":null,"abstract":"","PeriodicalId":34409,"journal":{"name":"FS Reports","volume":"6 1","pages":"Page 16"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143687143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
FS ReportsPub Date : 2025-03-01DOI: 10.1016/j.xfre.2025.02.005
Richard J. Paulson M.D., M.S.
{"title":"Natural versus programmed frozen embryo transfer cycles: does the real difference lie in the duration of progesterone exposure prior to embryo transfer?","authors":"Richard J. Paulson M.D., M.S.","doi":"10.1016/j.xfre.2025.02.005","DOIUrl":"10.1016/j.xfre.2025.02.005","url":null,"abstract":"","PeriodicalId":34409,"journal":{"name":"FS Reports","volume":"6 1","pages":"Pages 1-2"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143687136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
FS ReportsPub Date : 2025-03-01DOI: 10.1016/j.xfre.2025.01.002
Angela Li M.D. , Ariel L. Scalise M.P.H. , Emma Mayette , Nicolette McGeorge Ph.D. , Kaitlyn James Ph.D. , Shruthi Mahalingaiah M.D.
{"title":"Considerations on optimizing the patient experience during assisted reproductive technology treatment: a qualitative analysis","authors":"Angela Li M.D. , Ariel L. Scalise M.P.H. , Emma Mayette , Nicolette McGeorge Ph.D. , Kaitlyn James Ph.D. , Shruthi Mahalingaiah M.D.","doi":"10.1016/j.xfre.2025.01.002","DOIUrl":"10.1016/j.xfre.2025.01.002","url":null,"abstract":"<div><h3>Objective</h3><div>To study the structural and human factors that negatively and positively influence the patient experience during assisted reproductive technology (ART) treatment.</div></div><div><h3>Design</h3><div>Qualitative study involving 15 patients who had previously undergone ART, interviewed between August and October 2022. Consented participants underwent semistructured interviews. Transcripts were coded through the constant comparative method, and reflexive thematic analysis was performed to identify predominant themes.</div></div><div><h3>Subjects</h3><div>Individuals who underwent ART between January 2017 and April 2022.</div></div><div><h3>Exposure</h3><div>Assisted reproductive technology with transfer of at least one embryo.</div></div><div><h3>Main Outcome Measures</h3><div>Factors positively and negatively influencing the patient experience.</div></div><div><h3>Results</h3><div>Themes identified from factors that negatively influenced care were the high burden and complexity of financing fertility treatment, unsatisfactory provider-patient communication, self-administration of injectable medications, and the complex and unpredictable nature of fertility treatment. Themes in factors that positively influenced care were positive provider rapport and collaborative decision making, social support networks, and alternative health therapies including acupuncture.</div></div><div><h3>Conclusion</h3><div>Patients faced challenges with treatment financing, poor provider communication, and self-administration of injectable medications. However, positive provider relationships, social support, and complementary therapies such as acupuncture were identified as helpful factors.</div></div>","PeriodicalId":34409,"journal":{"name":"FS Reports","volume":"6 1","pages":"Pages 25-30"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143687082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
FS ReportsPub Date : 2025-03-01DOI: 10.1016/j.xfre.2024.11.008
Julia Häusler M.D. , Alexander M Quaas M.D., Ph.D. , Manuel Fischer Ph.D. , Andreas Schötzau M.Sc. , Fiona Pugin Ph.D. , Christian De Geyter M.D. , Ursula Gobrecht-Keller M.D. , Beatrice Mosimann M.D. , Gwendolin Manegold-Brauer M.D.
{"title":"Novel sonographic reference charts for early pregnancy based on known gestational age","authors":"Julia Häusler M.D. , Alexander M Quaas M.D., Ph.D. , Manuel Fischer Ph.D. , Andreas Schötzau M.Sc. , Fiona Pugin Ph.D. , Christian De Geyter M.D. , Ursula Gobrecht-Keller M.D. , Beatrice Mosimann M.D. , Gwendolin Manegold-Brauer M.D.","doi":"10.1016/j.xfre.2024.11.008","DOIUrl":"10.1016/j.xfre.2024.11.008","url":null,"abstract":"<div><h3>Objective</h3><div>To study pregnancy dating, we developed growth charts using data from pregnancies with known gestational age. The most widely used growth charts for ultrasonographic early pregnancy variables were developed decades ago and are based on dating by the last menstrual period. The aims of the study were to create growth charts for early pregnancy (including crown-rump length, gestational sac diameter, yolk sac diameter, and amniotic cavity diameter) for last menstrual period-dated spontaneous pregnancies and pregnancies conceived through assisted reproductive technology (ART) with known gestational age; and to compare crown-rump length measurements with two established traditional charts based on last menstrual period dating.</div></div><div><h3>Design</h3><div>Retrospective cohort study.</div></div><div><h3>Subjects</h3><div>Of 1,061 singletons, 2,803 crown-rump length measurements from 716 exactly dated ART gestations with 1,143 crown-rump length measurements from 345 spontaneous pregnancies, which were dated by the last menstrual period in women with regular cycles, were compared using nonlinear quantile regression.</div></div><div><h3>Exposure</h3><div>A total of 716 ART pregnancies and 345 spontaneous pregnancies underwent ultrasound examinations, with a median of four visits at various points during the first trimester.</div></div><div><h3>Main Outcome Measures</h3><div>Early pregnancy dating with growth charts based on crown-rump length, gestational sac-, yolk sac- and amniotic cavity diameter.</div></div><div><h3>Results</h3><div>Novel reference charts for ultrasound dating of gestational age based on crown-rump length from 4 + 6 to 10 + 6 gestational weeks were created. The difference of the 10th and 90th percentile was significantly higher in spontaneous compared with ART pregnancies (<em>P</em><.05). For the same crown-rump length, the gestational age of spontaneous pregnancies was estimated to be up to 4.08 days older than in ART pregnancies at the 90th percentile. Preexisting curves (Robinson/Fleming, Hadlock) aligned closely with the new reference curve mid-range but showed larger deviations at the extremes of assessed gestational ages.</div></div><div><h3>Conclusion</h3><div>Early pregnancy crown-rump length curves based on last menstrual period may overestimate gestational age. Using 2,803 crown-rump length measurements, we propose the current comprehensive charts for early pregnancy within a population with known gestational age for crown-rump length, gestational sac diameter, yolk sac diameter, and amniotic cavity diameter.</div></div>","PeriodicalId":34409,"journal":{"name":"FS Reports","volume":"6 1","pages":"Pages 52-59"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143687086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
FS ReportsPub Date : 2025-03-01DOI: 10.1016/j.xfre.2024.12.005
Kaitlin Doody M.D. , Catherine Gordon M.D. , Amanda Adeleye M.D. , Joseph Letourneau M.D. , Peter McGovern M.D. , Rhiana Saunders M.D. , Ryan Heitmann D.O. , Molly Quinn M.D.
{"title":"The obstetrics and gynecology resident experience in reproductive endocrinology and infertility: a survey of residency program directors","authors":"Kaitlin Doody M.D. , Catherine Gordon M.D. , Amanda Adeleye M.D. , Joseph Letourneau M.D. , Peter McGovern M.D. , Rhiana Saunders M.D. , Ryan Heitmann D.O. , Molly Quinn M.D.","doi":"10.1016/j.xfre.2024.12.005","DOIUrl":"10.1016/j.xfre.2024.12.005","url":null,"abstract":"<div><h3>Objective</h3><div>To provide an updated appraisal of resident reproductive endocrinology and infertility (REI) education in obstetrics and gynecology (OBGYN) residency training.</div></div><div><h3>Design</h3><div>An anonymous survey was distributed to all program directors of Accreditation Council for Graduate Medical Education–accredited OBGYN residency programs (n = 282) in 2022. The survey queried program directors regarding program demographics, time residents spent on the REI rotation, vacation policy, off-service responsibilities, related resident research, and overall resident interest in pursuing REI fellowship training.</div></div><div><h3>Subjects</h3><div>OBGYN residency program directors.</div></div><div><h3>Exposure</h3><div>Not applicable.</div></div><div><h3>Main Outcome Measures</h3><div>The primary outcomes of interest were program characteristics associated with REI-related research and resident interest in pursuing REI fellowship training.</div></div><div><h3>Results</h3><div>Eighty-seven program directors responded for a response rate of 31%. Thirty-eight programs (43.7%) reported that residents rotate in an academic practice, and 24 programs (27.6%) reported an affiliated REI fellowship program. Over one third of program directors reported that it is “common” or “very common” for residents to be pulled from the REI rotation to other services. Programs that had residents rotate earlier in their training were more likely to have residents apply to REI fellowship and have peer-reviewed REI publications.</div></div><div><h3>Conclusion</h3><div>There are varied experiences among OBGYN residencies regarding the REI resident rotation. Resident interest in applying for REI fellowships and publishing REI-related research is associated with rotating early in training, exposure to an academic practice, and having an affiliated REI fellowship program.</div></div>","PeriodicalId":34409,"journal":{"name":"FS Reports","volume":"6 1","pages":"Pages 73-78"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143687179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
FS ReportsPub Date : 2025-03-01DOI: 10.1016/j.xfre.2025.02.007
Rachel S. Mandelbaum M.D.
{"title":"Glucagon-Like Peptide-1 Receptor agonists: A magic bullet or a double-edged sword?","authors":"Rachel S. Mandelbaum M.D.","doi":"10.1016/j.xfre.2025.02.007","DOIUrl":"10.1016/j.xfre.2025.02.007","url":null,"abstract":"","PeriodicalId":34409,"journal":{"name":"FS Reports","volume":"6 1","pages":"Page 10"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143687139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Counseling couples with male factor infertility on their chances with testicular sperm in in vitro fertilization/intracytoplasmic sperm injection cycles: What tools do we have?","authors":"Rachel Passarelli M.D., Danielle Velez Leitner M.D.","doi":"10.1016/j.xfre.2025.01.012","DOIUrl":"10.1016/j.xfre.2025.01.012","url":null,"abstract":"","PeriodicalId":34409,"journal":{"name":"FS Reports","volume":"6 1","pages":"Page 15"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143687142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
FS ReportsPub Date : 2025-03-01DOI: 10.1016/j.xfre.2024.11.004
Lucille G. Cheng B.A. , Kathleen Hwang M.D.
{"title":"Reply of the authors: “Isolated teratospermia in fertile men: a call for reassessment”","authors":"Lucille G. Cheng B.A. , Kathleen Hwang M.D.","doi":"10.1016/j.xfre.2024.11.004","DOIUrl":"10.1016/j.xfre.2024.11.004","url":null,"abstract":"","PeriodicalId":34409,"journal":{"name":"FS Reports","volume":"6 1","pages":"Page 96"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143687134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}