Proceedings of the 19th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. 'Magnificent Milestones and Emerging Opportunities in Medical Engineering' (Cat. No.97CH36136)最新文献

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A microchip electrochemical immunosensor fabricated using micromachining techniques 一种微芯片电化学免疫传感器
Jin-Woo Choi, Ying Ding, C. Ahn, H. Halsall, W. Heineman
{"title":"A microchip electrochemical immunosensor fabricated using micromachining techniques","authors":"Jin-Woo Choi, Ying Ding, C. Ahn, H. Halsall, W. Heineman","doi":"10.1109/IEMBS.1997.758812","DOIUrl":"https://doi.org/10.1109/IEMBS.1997.758812","url":null,"abstract":"Using micromachining techniques, an electrochemical immunosensor has been designed, fabricated and tested on a Pyrex glass wafer. The sensor has an electrochemical cell that is composed of a reference, an auxiliary and two working electrodes on a spin-coated polyimide film, where the reference electrode is silver and the others are platinum. The polyimide film is used for antibody immobilization instead of a polystyrene sheet which is usually used in conventional immunosensors. A reaction chamber is fabricated separately on a silicon wafer using anisotropic etching techniques. The electrochemical cell on a glass wafer and the reaction chamber on a silicon wafer are then bonded together to construct the immunosensor using polymer bonding techniques. Fabricated immunosensors are tested by the method of cyclic voltammetry (CV) before analyzing the antigen-antibody reaction. Test antibodies are well attached to the polyimide substrate, and the results of the CV test shows that this immunosensor can be successfully applied for electrochemical immunoassay.","PeriodicalId":342750,"journal":{"name":"Proceedings of the 19th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. 'Magnificent Milestones and Emerging Opportunities in Medical Engineering' (Cat. No.97CH36136)","volume":"77 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1997-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117238707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
Subject specific EEG patterns during motor imaginary [sic.: for imaginary read imagery] 运动想象过程中受试者特定的脑电图模式[原文如此]。:用于虚构的阅读意象]
A. Schloegl, C. Neuper, G. Pfurtscheller
{"title":"Subject specific EEG patterns during motor imaginary [sic.: for imaginary read imagery]","authors":"A. Schloegl, C. Neuper, G. Pfurtscheller","doi":"10.1109/IEMBS.1997.757001","DOIUrl":"https://doi.org/10.1109/IEMBS.1997.757001","url":null,"abstract":"Left- and right-hand movement imagery is accompanied by an EEG event-related desynchronization (ERD) over the contralateral hand area. The time courses of the ERD from two brain-computer interface experiments were investigated by the calculation of instantaneous band power changes and by adaptive autoregressive model parameters combined with linear discriminant analysis. Subject-specific differences of the EEG reactivity patterns were observed.","PeriodicalId":342750,"journal":{"name":"Proceedings of the 19th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. 'Magnificent Milestones and Emerging Opportunities in Medical Engineering' (Cat. No.97CH36136)","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1997-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128308553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 15
Spatiotemporal QRST cancellation techniques for improved characterization of atrial fibrillation in the surface ECG 时空QRST对消技术用于改善体表心电图心房颤动的表征
M. Stridh, L. Sornmo
{"title":"Spatiotemporal QRST cancellation techniques for improved characterization of atrial fibrillation in the surface ECG","authors":"M. Stridh, L. Sornmo","doi":"10.1109/IEMBS.1997.754459","DOIUrl":"https://doi.org/10.1109/IEMBS.1997.754459","url":null,"abstract":"A new two-step approach to QRST complex cancellation in ECGs with atrial fibrillation is presented in which spatiotemporal properties of the ECG are considered. The method was found to produce QRS related residuals with a substantially lower amplitude and thereby the resulting residual ECG should be better suited for spectral analysis.","PeriodicalId":342750,"journal":{"name":"Proceedings of the 19th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. 'Magnificent Milestones and Emerging Opportunities in Medical Engineering' (Cat. No.97CH36136)","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1997-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128309616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 10
Fast Static Image Reconstruction using Adaptive Mesh Grouping Method in EIT 基于自适应网格分组方法的EIT快速静态图像重建
K. Cho, E. Woo, Sung Tack Ko
{"title":"Fast Static Image Reconstruction using Adaptive Mesh Grouping Method in EIT","authors":"K. Cho, E. Woo, Sung Tack Ko","doi":"10.1109/IEMBS.1997.754574","DOIUrl":"https://doi.org/10.1109/IEMBS.1997.754574","url":null,"abstract":"For the practical applications of the electrical impedance tomography (EIT) technology, it is essential to reconstruct static images with a higher spatial resolution in a reasonable amount of processing time. Using the conventional EIT static image reconstruction algorithms, however, the processing time increases rapidly with poor convergence characteristics as we try to get a higher spatial resolution. In order to overcome this problem, we propose an adaptive mesh grouping method based on a fuzzy-GA algorithm. Computer simulations using the improved Newton-Raphson method combined with the adaptive mesh grouping algorithm showed a promising result that we can significantly reduce the computation time without sacrificing the spatial resolution.","PeriodicalId":342750,"journal":{"name":"Proceedings of the 19th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. 'Magnificent Milestones and Emerging Opportunities in Medical Engineering' (Cat. No.97CH36136)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1997-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128692206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
A high voltage stimulator for small electrode electrocutaneous stimulation 一种用于小电极皮肤电刺激的高压刺激器
C. Poletto, C. Van Doren
{"title":"A high voltage stimulator for small electrode electrocutaneous stimulation","authors":"C. Poletto, C. Van Doren","doi":"10.1109/IEMBS.1997.756809","DOIUrl":"https://doi.org/10.1109/IEMBS.1997.756809","url":null,"abstract":"A high voltage stimulator has been designed to allow transcutaneous stimulation of tactile fibers of the fingertip. The output stage is based upon an improved Howland current pump topology, modified to allow high load impedances and small currents. The current output accuracy is better than 15% for 1 to 10 mA for 30 /spl mu/sec pulses. The rise time for square pulses is less than 2 /spl mu/sec. Common mode latch-up power supply problems are discussed.","PeriodicalId":342750,"journal":{"name":"Proceedings of the 19th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. 'Magnificent Milestones and Emerging Opportunities in Medical Engineering' (Cat. No.97CH36136)","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1997-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128373464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 12
Slip detection using the power spectrum of sensory nerve recordings 利用感觉神经记录的功率谱进行滑动检测
A. Guzman, R. Riso, D. Durand
{"title":"Slip detection using the power spectrum of sensory nerve recordings","authors":"A. Guzman, R. Riso, D. Durand","doi":"10.1109/IEMBS.1997.758739","DOIUrl":"https://doi.org/10.1109/IEMBS.1997.758739","url":null,"abstract":"In cases of spinal cord injury primary sensory afferents below the injury remain fully functional and could be used as natural sensors to provide a feedback signal for FNS control. This paper presents a slip detection method using the power spectrum of spiral cuff ENG. The central toe pad of a cat is used as a model for human glabrous skin. Three modes of tactile stimuli (slip, stretch and pressure) are applied to the central toe pad in an anesthetized preparation while recording the electroneurogram (ENG) from the tibial nerve using a three band spiral cuff electrode. Discriminant analysis of the power spectra of 10 ms data segments was used to classify randomly selected segments as \"slip\" or \"non-slip\". The highest classification rate (81% correct) was achieved by normalizing the power spectra by the total power of the segment. Three window sizes (10 ms, 20 ms and 40 ms) were compared and found to have no effect on classification rate. The classification rate appeared to correlate well with the velocity of the slipping object, ranging from 55% to 90% for velocities of 2.5 mm/s to 15 mm/s. In conclusion, the power spectrum can be used to distinguish slip from other types of tactile stimulus and higher velocities are detected more reliably.","PeriodicalId":342750,"journal":{"name":"Proceedings of the 19th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. 'Magnificent Milestones and Emerging Opportunities in Medical Engineering' (Cat. No.97CH36136)","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1997-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128494597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Kinematic model relating complex 2D smooth pursuit eye movements and Purkinje cell firing rate in cerebellar flocculus and paraflocculus of the rhesus monkey 猕猴小脑小叶和小叶旁浦肯野细胞放电率与复杂二维平滑追踪眼运动的运动学模型
M. Suh, H. Leung, R. Kettner
{"title":"Kinematic model relating complex 2D smooth pursuit eye movements and Purkinje cell firing rate in cerebellar flocculus and paraflocculus of the rhesus monkey","authors":"M. Suh, H. Leung, R. Kettner","doi":"10.1109/IEMBS.1997.756990","DOIUrl":"https://doi.org/10.1109/IEMBS.1997.756990","url":null,"abstract":"Single-neuron responses from the flocculus and paraflocculus of the cerebellum were recorded from rhesus monkeys while they tracked targets moving along complex and simple 2D trajectories. Each neuron was analyzed using a multi-linear regression model that expressed the instantaneous firing rate of the neuron as a function of the instantaneous 2D position, velocity, and acceleration of the eye. In all cases, the model provided a good description of the data. In addition, the model explains why some neurons show relatively complex responses including a systematic preference for clockwise (CW) versus counterclockwise (CCW) circular target motions, while others low simpler responses. Most neurons had position and velocity preferred directions that were in alignment. These neurons had relatively simple response profiles with similar response amplitudes during CW versus CCW circular pursuit. Other neurons had position and velocity preferred directions that were not aligned and that differed by as much as 90/spl deg/. These neurons had more complex response properties including a preference for either CW or CCW circular pursuit. This suggests that neurons with simple responses receive inputs with similar spatial tuning properties, while complex responses result from inputs with different spatial tuning properties.","PeriodicalId":342750,"journal":{"name":"Proceedings of the 19th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. 'Magnificent Milestones and Emerging Opportunities in Medical Engineering' (Cat. No.97CH36136)","volume":"66 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1997-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128498838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Heating distribution of multipolar radiofrequency ablation catheters 多极射频消融导管的热分布
M. Mirotznik, D.T. Demazumder, J.R. Jones, D. Schwartzman
{"title":"Heating distribution of multipolar radiofrequency ablation catheters","authors":"M. Mirotznik, D.T. Demazumder, J.R. Jones, D. Schwartzman","doi":"10.1109/IEMBS.1997.754491","DOIUrl":"https://doi.org/10.1109/IEMBS.1997.754491","url":null,"abstract":"Radiofrequency (RF) catheter ablation therapy has been recognized as an effective treatment for a variety of cardiac arrhythmias. In fact, for several arrhythmias, including Wolf-Parkinson-White Syndrome, this technique is greater than 95% curative. However, when applied for the treatment of ventricular tachycardia or atrial fibrillation, RF catheter ablation has been far less successful. It is believed that the small lesions produced by current RF catheters are not sufficient to reliably treat these disorders. This study presents experimental measurements of heating patterns of commercially available multipolar RF ablation catheters. Three different electrode configurations were investigated. Results revealed significant differences in the catheter specific absorption rate pattern across the different configurations. Further in vitro and in vivo studies are underway to investigate these effects on actual lesion formation.","PeriodicalId":342750,"journal":{"name":"Proceedings of the 19th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. 'Magnificent Milestones and Emerging Opportunities in Medical Engineering' (Cat. No.97CH36136)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1997-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128976212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
ECG signal compression using adaptive prediction 基于自适应预测的心电信号压缩
S. Szilágyi, L. Szilágyi, L. Dávid
{"title":"ECG signal compression using adaptive prediction","authors":"S. Szilágyi, L. Szilágyi, L. Dávid","doi":"10.1109/IEMBS.1997.754475","DOIUrl":"https://doi.org/10.1109/IEMBS.1997.754475","url":null,"abstract":"A new ECG compression method is presented. First, a prefiltering is effected, followed by a QRS detection. After that the R peaks are localized and the signal is divided into R-R intervals, the original signal can be filtered with less characteristics distortion. This filter is based upon a pondered adaptive long term prediction method. The suggested real-time compression was performed for one of the channels of the MIT/BIH database samples, and can reduce the size of the signal at about 50 bits for one second, without exceeding 10 percent at root mean square reconstruction error (RMSRE). If it is necessary, the algorithm can be used for exact coding, but the size of the concentrated signal highly depends on the sampling rate and resolution. The used adaptive entropy coder introduces about 10 times less redundancy than an optimized Huffman coder.","PeriodicalId":342750,"journal":{"name":"Proceedings of the 19th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. 'Magnificent Milestones and Emerging Opportunities in Medical Engineering' (Cat. No.97CH36136)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1997-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129021157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 14
Effects of body axis on estimation of horizontal linear translation 体轴对水平直线平移估计的影响
M. Markmiller, L. Young
{"title":"Effects of body axis on estimation of horizontal linear translation","authors":"M. Markmiller, L. Young","doi":"10.1109/IEMBS.1997.756902","DOIUrl":"https://doi.org/10.1109/IEMBS.1997.756902","url":null,"abstract":"Extending the work of Israel et al [1993], this study investigated human path integration of linear horizontal motion and, in particular, the presence of different responses between body axes of motion. Six blindfolded subjects were passively accelerated along a horizontal track and instructed to signal when they perceived themselves passing a remembered target. We tested three orientations: upright Y-axis (lateral), and two supine Z-axes (starting acceleration headward or footward). The cart trajectory was specified by a square wave in acceleration. Two acceleration levels (1.0 and 0.2 m/s2) and two target distances (0.8 and 2.4 m) were used. The subjects each performed four repetitions of each set of parameters. We consistently found (501/554) anticipatory responses, with the only late responses occurring on the return path; this agrees with the findings of Israel et al. Footward acceleration produced the greatest anticipation, followed by Y-axis and headward accelerations. However, a striking asymmetry appeared when responses to headward and footward accelerations in the supine orientation were compared to one another. ANOVA on the latencies for both pooled and individual subjects showed orientation as significant (P<0.001). This asymmetry may reflect nonlinearities in the generation or processing of otolith information. Moreover, from a behavioral standpoint, the heightened anticipation during footward motions may be an expression of the human need to be particularly sensitive to downward accelerations, such as falls.","PeriodicalId":342750,"journal":{"name":"Proceedings of the 19th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. 'Magnificent Milestones and Emerging Opportunities in Medical Engineering' (Cat. No.97CH36136)","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1997-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124550009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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