A. Jadhav, R. Gupta, E. Levy, O. Zaidat, D. Yavagal, J. Saver
{"title":"P-021 Tiger study: shorter arterial puncture to revascularization times and first pass effect improves angiographic and clinical outcomes","authors":"A. Jadhav, R. Gupta, E. Levy, O. Zaidat, D. Yavagal, J. Saver","doi":"10.1136/NEURINTSURG-2021-SNIS.57","DOIUrl":"https://doi.org/10.1136/NEURINTSURG-2021-SNIS.57","url":null,"abstract":"P-021 Table 1 Group mTICI 2b-3 After first Tiger pass D NIHSS @ 24 hrs mRS 0-2 @ 90 days mRS 0-1@ 90 days sICH @ 24 hours Mortality@ 90 days ENT Arterial puncture to Revascularization £25 min, 52% (median 17) 87.5% -10.3 73.5% 66.2% 0 11.1% 1.4% >25 min, 48% (median 44) 34.8% -8.3 51.5% 33.3% 2.9% 19.7% 4.5% P value 0.00001 0.14 0.009 0.0001 0.13 0.16 0.28 LKW to Arterial puncture £178 min, 50% (median 125) 56.8% -9.9 57.1% 47.1% 1.3% 14.9% 1.4% >178min, 50% (median 291.5) 63.0% -7.7 63.0% 47.9% 2.7% 18.9% 4.1% P value 0.44 0.11 0.47 0.92 0.55 0.51 0.31 LKW to Revascularization £220 min, 50% (median 151.5) 64.3% -10.5 62.1% 50.0% 0 14.5% 1.4% >220 min, 50% (median 320) 60.3% -7.7 63.2% 50.0% 2.9% 15.9% 4.3% P value 0.63 0.09 0.90 1.00 0.15 0.81 0.31 Abstracts A36 J NeuroIntervent Surg 2021;13(Suppl 1):A1–A156 on S etem er 3, 2023 by gest. P rocted by coright. http/jnis.bm jcom / J N eurotervent S urg: frst pulished as 10.1136intsurg-2021-S N IS 57 on 26 July 221. D ow nladed fom faster (£220 min) compared with slower (>220 min) time from LKW to revascularization were not associated with statistically significant differences in outcome. There were no statistically differences in safety outcomes in faster compared to slower times. Conclusions Among patients with acute ischemic stroke due to large vessel occlusion, faster time from arterial puncture to revascularization is strongly associated with improved angiographic and 3 month clinical outcomes. These data emphasize the importance of rapid and efficient catheter navigation, device deployment, and clot retrieval for best patient outcomes. Disclosures A. Jadhav: None. R. Gupta: None. E. Levy: None. O. Zaidat: None. D. Yavagal: None. J. Saver: None. P-022 ENDOVASCULAR TREATMENT OF WIDE-NECK BIFURCATION ANEURYSMS: A SINGLE-CENTER EXPERIENCE AND PARADIGM SHIFT A Copelan*, J Delgado Almandoz, Y Kayan, J Scholz. Neurointerventional Radiology, Abbott Northwestern Hospital, Minneapolis, MN 10.1136/neurintsurg-2021-SNIS.58 Purpose To present our single center experience utilizing balloon-assisted coiling (BAC), stent-assisted coiling (SAC) and Woven Endo-Bridge (WEB) embolization for the treatment of both ruptured and unruptured wide-necked bifurcation aneurysms (WNBAs) with a focus on the safety and efficacy profiles of each technique. Methods We retrospectively reviewed all WNBAs treated at our institution with BAC, SAC, and WEB embolization between January 2012 and August 2020. Required aneurysm characteristics were in line with the pivotal WEB Intrasaccular Therapy (WEB-IT) study and included: ruptured or unruptured status; size of dome between 3mm and 10mm; wide-neck defined by neck size 4 mm or dome-to-neck ratio <2; and location limited to the basilar tip (BTA), internal carotid artery terminus (ICA-T), anterior communicating artery complex (ACOM), and middle cerebral artery (MCA) bifurcation. We collected patient demographic variables, aneurysm characteristics, intraprocedural technical difficulti","PeriodicalId":341680,"journal":{"name":"Oral poster abstracts","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130604762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Nguyen, G. Cortez, M. Baretta, A. Aghaebrahim, E. Sauvageau, R. Hanel
{"title":"P-032 Disparities in stroke: influence of socioeconomic status and race on timely access to mechanical thrombectomy","authors":"A. Nguyen, G. Cortez, M. Baretta, A. Aghaebrahim, E. Sauvageau, R. Hanel","doi":"10.1136/neurintsurg-2021-snis.68","DOIUrl":"https://doi.org/10.1136/neurintsurg-2021-snis.68","url":null,"abstract":"of State Health Services. Results The number of AIS cases dropped substantially from 10,745 per quarter in the pre-pandemic period to 9,277 in the pandemic period (-14%) in Texas. The percentage of patients aged younger than 65 (39.0% vs 40.4%, p=0.014) and LVO stroke (30.0% vs 32.7%, p<0.001) slightly increased. Percentages of admission to CSC (39.1% vs 39.5%, p=0.57) and admission through inter-hospital transfer (9.6% vs 9.3%, p=0.35) remained similar between pre-pandemic and pandemic periods. There was also no significant change in the use of IV-tPA (14.1% vs 13.6%, P=0.20) or EVT (5.4% VS 5.8%, P=0.12). In-hospital mortality slightly increased from 2.9% to 3.2% but it was not statistically significant (p=0.13). However, the percentage of death or hospice discharge increased from 7.6% to 8.4% (p=0.003) and age and LVO type adjusted odds ratio was 1.13 (95% CI 1.04-1.23). Conclusion In this population-level study, significant decreases in AIS volume were observed with slightly higher incidence in younger population and higher LVO strokes. Rates of thrombolysis and thrombectomy remained unchanged but patients appeared to have worse outcomes. Disclosures Y. Kim: None. S. Khose: None. S. Salazar-Marioni: None. R. Abdelkhaleq: None. S. Sheth: None.","PeriodicalId":341680,"journal":{"name":"Oral poster abstracts","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114381801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Spiotta, C. Schirmer, B. Bohnstedt, R. Bellon, H. Hawk
{"title":"P-048 Safety and performance of the penumbra smart coil system for patients with posterior aneurysms","authors":"A. Spiotta, C. Schirmer, B. Bohnstedt, R. Bellon, H. Hawk","doi":"10.1136/NEURINTSURG-2021-SNIS.84","DOIUrl":"https://doi.org/10.1136/NEURINTSURG-2021-SNIS.84","url":null,"abstract":"","PeriodicalId":341680,"journal":{"name":"Oral poster abstracts","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128056751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"P-038 Demographic disparities in proximity to certified stroke care in the United States","authors":"C. Yu, T. Blaine, P. Panagos, Akash P. Kansagra","doi":"10.1136/neurintsurg-2021-snis.74","DOIUrl":"https://doi.org/10.1136/neurintsurg-2021-snis.74","url":null,"abstract":"","PeriodicalId":341680,"journal":{"name":"Oral poster abstracts","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117236277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"P-046 Factors associated with incomplete occlusion of intracranial aneurysms at follow up after treatment with woven endobridge (WEB) device","authors":"K. Javed, A. Fortunel, N. Haranhalli, D. Altschul","doi":"10.1136/neurintsurg-2021-snis.82","DOIUrl":"https://doi.org/10.1136/neurintsurg-2021-snis.82","url":null,"abstract":"Purpose We present core-lab adjudicated immediate post-proce-dural angiographic outcomes following endovascular treatment of side wall and bifurcation wide-necked aneurysms using MICRUSFRAME and GALAXY coils and various adjunctive devices within the STERLING registry. Methods STERLING is an ongoing single-arm prospective post-market surveillance registry evaluating ruptured/unrup-tured aneurysms treated with MICRUSFRAME and GALAXY coils (Cerenovus, Irvine, CA). All cases of wide-neck aneurysm treatment (neck > 4 mm or dome-to-neck ratio < 2) were extracted from the registry. Subgroups were defined according to the adjunctive devices (if any) used during treatment. The primary outcome measures were core-lab adjudicated modified Raymond-Roy (mRR) occlusion at final procedural angiogram, and procedure-related adverse events.","PeriodicalId":341680,"journal":{"name":"Oral poster abstracts","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132531243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. Cortez, R. Turner, A. Monteiro, A. Puri, A. Siddiqui, J. Mocco, J. Vargas, A. Kühn, S. Majidi, M. Chaudry, A. Aghaebrahim, A. Turk, E. Sauvageau, R. Hanel
{"title":"P-013 Navigating the walrus: a large bore balloon guide catheter for acute ischemic stroke thrombectomy","authors":"G. Cortez, R. Turner, A. Monteiro, A. Puri, A. Siddiqui, J. Mocco, J. Vargas, A. Kühn, S. Majidi, M. Chaudry, A. Aghaebrahim, A. Turk, E. Sauvageau, R. Hanel","doi":"10.1136/neurintsurg-2021-snis.49","DOIUrl":"https://doi.org/10.1136/neurintsurg-2021-snis.49","url":null,"abstract":"rates as other commercially available catheters with no safety concerns. More prospective clinical data is needed to fully assess the Q Aspiration Catheter. Abbreviations AIS (acute ischemic stroke), MT (mechanical thrombectomy), ASPECTs (Alberta Stroke Program Early CT Score), mTICI (modified TICI score), NIHSS (National Insti-tute of Health Stroke Scale), mRS (modified Rankin Scale), ENT (embolization to a new territory), sICH (symptomatic intracranial hemorrhage)","PeriodicalId":341680,"journal":{"name":"Oral poster abstracts","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116041542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T. Lázaro, P. Cotton, C. English, K. Katlowitz, O. Tanweer, D. Raper
{"title":"P-019 Clinical significance of contrast staining after mechanical thrombectomy for acute ischemic stroke","authors":"T. Lázaro, P. Cotton, C. English, K. Katlowitz, O. Tanweer, D. Raper","doi":"10.1136/neurintsurg-2021-snis.55","DOIUrl":"https://doi.org/10.1136/neurintsurg-2021-snis.55","url":null,"abstract":"gadolinium. Enhancement data variables from the MRI that were recorded included pattern (circumferential versus eccen-tric) and amount of maximal contrast enhancement based on region of interest differences in the region of highest T1 sig-nal between post and pre-contrast T1 sequences. Following thrombectomy, the type and number of passes with each device was recorded. Results 10 adult patients (6 F, Mean age of 65.7 years) were included in this study. Two received stent retriever with aspiration catheter, 7 received stent retriever only, and 1 received aspiration only. All 10 patients demonstrated circumferential enhancement in the region of retrieved clot, including the one patient who received aspiration only. Of the 9 patients that received the stent retriever, recanalization was achieved in 1 pass in 4, while in the other 5 patients, recanalization was achieved after multiple passes (range 2-4 passes). Dichot-omizing the data between 1 and multiple passes, there was a difference in the amount of mean maximal enhancement of the involved vessel wall (single pass: 75, Std Dev 28.39 vs multiple passes: 110.6, Std Dev 51.75), although this did not reach statistical significance due to a small number of patients. All patients showed circumferential wall enhancement despite type of thrombectomy technique, suggesting that all techniques may be associated with a similar mechanism of endothelial wall injury. Moreover, those patients who required multiple passes of the stent retriever for recanalization demonstrated a higher mean maximal enhancement when compared to those patients who required just one pass. Further explora-tion an increased number of patients is warranted.","PeriodicalId":341680,"journal":{"name":"Oral poster abstracts","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130681395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Koester, A. Yengo-Kahn, M. Feldman, M. Lan, P. Patel, A. Churchwell, R. Chitale
{"title":"P-059 Race as a social determinant of poor outcomes following unruptured aneurysm surgery","authors":"S. Koester, A. Yengo-Kahn, M. Feldman, M. Lan, P. Patel, A. Churchwell, R. Chitale","doi":"10.1136/neurintsurg-2021-snis.95","DOIUrl":"https://doi.org/10.1136/neurintsurg-2021-snis.95","url":null,"abstract":"Methods The ULTRA Registry is a prospective database of patients with small (< 5 mm) intracranial aneurysms treated exclusively with Target ® Ultrasoft and Nano coils. The primary endpoints are target aneurysm re-intervention or target aneurysm rupture during follow up, and secondary endpoints include residual aneurysm rates and device related or procedural adverse events.","PeriodicalId":341680,"journal":{"name":"Oral poster abstracts","volume":"19 40","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132747553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Hitomi, M. Jumaa, S. Zaidi, J. Shawver, Andrea Korsnack, A. Castonguay, Richard R. Burgess, Vieh M Kung, H. Salahuddin
{"title":"P-036 Sensitivity of the RACW score in the detection of large vessel occlusions during working and non-working hours","authors":"E. Hitomi, M. Jumaa, S. Zaidi, J. Shawver, Andrea Korsnack, A. Castonguay, Richard R. Burgess, Vieh M Kung, H. Salahuddin","doi":"10.1136/neurintsurg-2021-snis.72","DOIUrl":"https://doi.org/10.1136/neurintsurg-2021-snis.72","url":null,"abstract":"","PeriodicalId":341680,"journal":{"name":"Oral poster abstracts","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131246741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Schwartz, B. Fennell, C. Settanni, N. Norris, T. Becker
{"title":"P-030 Voxel-based calculations of intrasaccular aneurysm and device volume fill","authors":"S. Schwartz, B. Fennell, C. Settanni, N. Norris, T. Becker","doi":"10.1136/neurintsurg-2021-snis.66","DOIUrl":"https://doi.org/10.1136/neurintsurg-2021-snis.66","url":null,"abstract":"Introduction Various embolization techniques are available for intracranial aneurysms. The precise volume measurement of an aneurysm sac can help improve embolization techniques, such as: coils, liquid embolics, flow disruptors, and flow diverters. Aneurysm sizing and volumetric information help interventionalists assess flow and stability pre-treatment and potential remnant or recanalization risks post-treatment. Materials and Methods This research project applies voxelbased volume calculations, from CT or MRI medical imaging data, to determine accurate 3-D aneurysm volume calculations. Additionally, the application can display clinically relevant parameters, such as aneurysm neck diameter, dome height and midline-dome width (for dome:neck (D:N) ratio calculations). To develop the measurement techniques, wide-neck canine aneurysm models (n=10) were scanned with a Siemens Inveon Micro-CT scanner (University of Arizona TBIR, Tucson, AZ) and analyzed with InVesalius 3.0 software (Ministry of Health, Brazil). The software loads the imaging data, discretizes the intrasaccular aneurysm, separating the device volume from the aneurysm sac. This data was compared to physical measurements of excised aneurysms and calibrated 2-D angiographic images. Results Invesalius image processing techniques helped determine the domain of aneurysms with less than 5% volumetric error, when compared to measurements recorded during the aneurysm creation surgery. Current measurement techniques in 2-D planes have errors as high as 30%. This technique helps determine the macroscopic properties of aneurysms, as well as the volumes of abnormal aneurysm shapes. The software was also used to measure% fill of a liquid embolic (NeuroCURE) delivered to the 10 canine aneurysms. In all 10 cases the precise delivery of NeuroCURE resulted in 90100% aneurysm sac filling, versus < 30% for traditional coiling techniques. Conclusion As new aneurysm treatment devices are developed and greater% fill of the aneurysm sac is attempted, the need for precise aneurysm volume calculations will be of high priority. This project brings together clinical and engineering expertise to translate medical imaging data directly into volumetric measurements with highly precise calculations that are currently not available from 2-D angiographic images. Measuring the size and dimensional properties of aneurysms with voxel-based volume calculations provides a fast, reliable and repeatable resource for aneurysm assessment. This technique will help interventionalists appropriately assess risk and treatment options for a broad range of aneurysm morphologies. Disclosures S. Schwartz: 1; C; 5R42NS097069-03 (NIH Grant#)). B. Fennell: 1; C; 5R42NS097069-03 (NIH Grant #). C. Settanni: 1; C; 5R42NS097069-03 (NIH Grant #). N. Norris: 1; C; 5R42NS097069-03 (NIH Grant #). T. Becker: 1; C; 5R42NS097069-03 (NIH Grant #).","PeriodicalId":341680,"journal":{"name":"Oral poster abstracts","volume":"72 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114951864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}