P-019 Clinical significance of contrast staining after mechanical thrombectomy for acute ischemic stroke

T. Lázaro, P. Cotton, C. English, K. Katlowitz, O. Tanweer, D. Raper
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Abstract

gadolinium. Enhancement data variables from the MRI that were recorded included pattern (circumferential versus eccen-tric) and amount of maximal contrast enhancement based on region of interest differences in the region of highest T1 sig-nal between post and pre-contrast T1 sequences. Following thrombectomy, the type and number of passes with each device was recorded. Results 10 adult patients (6 F, Mean age of 65.7 years) were included in this study. Two received stent retriever with aspiration catheter, 7 received stent retriever only, and 1 received aspiration only. All 10 patients demonstrated circumferential enhancement in the region of retrieved clot, including the one patient who received aspiration only. Of the 9 patients that received the stent retriever, recanalization was achieved in 1 pass in 4, while in the other 5 patients, recanalization was achieved after multiple passes (range 2-4 passes). Dichot-omizing the data between 1 and multiple passes, there was a difference in the amount of mean maximal enhancement of the involved vessel wall (single pass: 75, Std Dev 28.39 vs multiple passes: 110.6, Std Dev 51.75), although this did not reach statistical significance due to a small number of patients. All patients showed circumferential wall enhancement despite type of thrombectomy technique, suggesting that all techniques may be associated with a similar mechanism of endothelial wall injury. Moreover, those patients who required multiple passes of the stent retriever for recanalization demonstrated a higher mean maximal enhancement when compared to those patients who required just one pass. Further explora-tion an increased number of patients is warranted.
P-019急性缺血性脑卒中机械取栓后对比染色的临床意义
钆。记录的MRI增强数据变量包括模式(周向与偏心)和基于对比前后T1序列之间最高T1信号区域的感兴趣区域差异的最大对比度增强量。取栓后,记录每个装置的通道类型和次数。结果本组共纳入10例成人患者,年龄65.7岁。2例接受支架置换器伴抽吸导管,7例仅接受支架置换器,1例仅接受抽吸。所有10例患者均表现出回收血块区域的周向增强,包括仅接受抽吸的1例患者。在9例接受支架取出器的患者中,4例患者1次通道即可实现再通,而另外5例患者多次通道即可实现再通(范围2-4次)。对1次和多次检查之间的数据进行二分类,受病灶血管壁的平均最大增强量存在差异(单次检查:75,Std / Dev 28.39 vs多次检查:110.6,Std / Dev 51.75),尽管由于患者数量少,这没有达到统计学意义。尽管采用了不同类型的取栓技术,但所有患者均表现出环壁增强,这表明所有技术都可能与内皮壁损伤的相似机制有关。此外,与那些只需要一次通道的患者相比,那些需要多次支架回收器进行再通的患者表现出更高的平均最大增强。进一步的探索,增加患者的数量是有必要的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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