Brain HemorrhagesPub Date : 2023-12-01DOI: 10.1016/j.hest.2023.02.002
Artur Eduardo Martio , Ana Luisa dos Santos Carregosa , Octávio Ruschel Karam , Wagner Lazaretto Padua , Paulo Moacir Mesquita Filho
{"title":"Spontaneous subdural effusion in a hospitalized Covid-19 patient: Case report","authors":"Artur Eduardo Martio , Ana Luisa dos Santos Carregosa , Octávio Ruschel Karam , Wagner Lazaretto Padua , Paulo Moacir Mesquita Filho","doi":"10.1016/j.hest.2023.02.002","DOIUrl":"10.1016/j.hest.2023.02.002","url":null,"abstract":"<div><p>Subdural effusions (SE) have already been associated with several viruses, but there are few associations with Covid-19 reported to date, and all of them had one thing in common: the presence of superimposed bacterial rhinosinusitis. Here we describe the case of a 76-year-old male patient that was transferred to our center due to severe SARS-CoV-2 infection and developed a SE during hospital stay. He presented sensory level impairment during hospitalization, but an initial Head CT scan showed no alterations. A new CT scan performed six days later evidentiated a bilateral SE. The patient had a cardiorespiratory arrest during the night of the same day, resulting in death. Covid-19 as a direct cause of subdural effusion (positive Covid-19 PCR in subdural fluid) has never before been reported in the literature, and, unfortunately, it was not possible to rule out or confirm this phenomenon in our case due to the rapid evolution of the clinical picture. However, our case clearly differs from the literature as the patient did not show any signs of sinus disease or intracranial hypotension, and the possible causes of the effusion boil down to spontaneity and the direct action of Covid-19 in the CNS and subdural space.</p></div>","PeriodicalId":33969,"journal":{"name":"Brain Hemorrhages","volume":"4 4","pages":"Pages 215-218"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9924043/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10766706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brain HemorrhagesPub Date : 2023-12-01DOI: 10.1016/j.hest.2023.11.003
Iris Tang
{"title":"Call for papers: Special issue on immune and peri-vascular cells in brain hemorrhage","authors":"Iris Tang","doi":"10.1016/j.hest.2023.11.003","DOIUrl":"10.1016/j.hest.2023.11.003","url":null,"abstract":"","PeriodicalId":33969,"journal":{"name":"Brain Hemorrhages","volume":"4 4","pages":"Page 221"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2589238X23000475/pdfft?md5=a206dbb872b2630d72232b8110cb330e&pid=1-s2.0-S2589238X23000475-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135514899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brain HemorrhagesPub Date : 2023-12-01DOI: 10.1016/j.hest.2023.09.001
Yeguang Xu , Ping Zhang , Chao Pan , Gang Chen
{"title":"Inauguration & 1st Annual Conference of Cerebral Hemorrhage Minimal Invasive Treatment Society of Chinese Stroke Association was successfully held","authors":"Yeguang Xu , Ping Zhang , Chao Pan , Gang Chen","doi":"10.1016/j.hest.2023.09.001","DOIUrl":"10.1016/j.hest.2023.09.001","url":null,"abstract":"<div><p>Inauguration & 1st Annual Conference of CSA Cerebral Hemorrhage Minimal Invasive Treatment Society was successfully held at China Optics Valley Convention & Exhibition Center in Wuhan, Hubei, Chian. During the conference, many well-known neurology experts in China conducted in-depth discussions on the research progress of minimal invasive treatment of cerebral hemorrhage, which benefited the participants a lot.</p></div>","PeriodicalId":33969,"journal":{"name":"Brain Hemorrhages","volume":"4 4","pages":"Pages 228-236"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2589238X23000359/pdfft?md5=893e267c3a0c06bee767c94fc2464070&pid=1-s2.0-S2589238X23000359-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73892035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Detection and successful endovascular treatment for a de novo intracranial pseudoaneurysm in early phase after traumatic brain injury","authors":"Sosho Kajiwara , Shuichi Tanoue , Masaru Hirohata , Yasuharu Takeuchi , Yu Hasegawa , Kimihiko Orito , Toshi Abe , Motohiro Morioka","doi":"10.1016/j.hest.2023.04.002","DOIUrl":"10.1016/j.hest.2023.04.002","url":null,"abstract":"<div><p>Traumatic intracranial pseudoaneurysm (TIP) after head trauma is rare, but it frequently ruptures in early phase. Although early detection and prompt treatment is important, the details are still unknown. Here, we report a case who was diagnosed with TIP in early phase after trauma and underwent endovascular treatment with parent artery occlusion (PAO), resulted in a good outcome.</p><p>A 17-year-old boy hospitalized for severe head trauma. Computed tomography (CT) revealed an acute epidural hematoma (AEDH) in the right middle fossa along with the fracture from the right lateral optic canal to the right superior orbital fissure, and CT angiography showed no obvious aneurysm at that time. CT angiography on 5 days showed an irregular shaped aneurysm at a C2-C3 posterior wall in the right internal carotid artery (ICA). As balloon occlusion test revealed complete ischemic tolerance, endovascular PAO was performed without any bypass. Postoperative imaging showed no hypoperfusion area.</p><p>Prompt diagnosis for TIP is important and the patients with skull fracture around ICA area are considered to provide cerebral angiography in early phase. In addition, TIP in early phase has a risk of rupture, suitable treatment strategy using BOT is important for the favorable outcome in those patients.</p></div>","PeriodicalId":33969,"journal":{"name":"Brain Hemorrhages","volume":"4 4","pages":"Pages 210-214"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2589238X2300013X/pdfft?md5=c2db712b1d6b41f1f4871389db362776&pid=1-s2.0-S2589238X2300013X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73209630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brain HemorrhagesPub Date : 2023-12-01DOI: 10.1016/j.hest.2023.05.001
Kenyu Hayashi , Prativa Sherchan , John H. Zhang , Yu Hasegawa
{"title":"Intranasal administration of collagenase develops cerebral microbleeds and vascular dementia in mice: In vivo pilot study","authors":"Kenyu Hayashi , Prativa Sherchan , John H. Zhang , Yu Hasegawa","doi":"10.1016/j.hest.2023.05.001","DOIUrl":"10.1016/j.hest.2023.05.001","url":null,"abstract":"<div><h3>Objective</h3><p>To establish a new animal model of lobar cerebral microbleeds (CMBs), we examined whether intranasal administration of collagenase induced CMBs in young mice which did not have hypertensive pathologic features.</p></div><div><h3>Methods</h3><p>We used thirty-two male CD1 mice (8–10 weeks old), which were received either phosphate-buffered saline (PBS) or collagenase by intranasal administration twice a day for 5 days. A dose response study was conducted, and motor function and number of CMBs was evaluated at one day after completing the intranasal administration. Temporal profile of cognitive impairment and number of CMBs through 7 days was evaluated after completing intranasal administration of 3.6U collagenase.</p></div><div><h3>Results</h3><p>The number of CMBs showed an increasing trend in a dose-dependent manner and higher number of CMBs were observed with 3.6U collagenase. Cognitive impairment and CMBs was observed in 3.6U collagenase groups up to 7 days after administration. In addition, successful brain delivery via intranasal route was comfirmed by administering fluorescein isothiocyanate-labeled bovine serum albumin.</p></div><div><h3>Conclusions</h3><p>Intranasal collagenase administration is a feasible and minimally invasive method to produce CMBs and cognitive impairment in mice. This model has potential for producing CMBs in animals with cerebral amyloid angiopathy such as transgenic mice models of Alzheimer’s disease.</p></div>","PeriodicalId":33969,"journal":{"name":"Brain Hemorrhages","volume":"4 4","pages":"Pages 183-188"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2589238X23000219/pdfft?md5=4a230da9cc5623989a30f27da0250028&pid=1-s2.0-S2589238X23000219-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87335657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Middle meningeal artery embolization may be an effective treatment for patients with chronic subdural hematoma resistant to atorvastatin","authors":"Yin Niu , Zhouyang Jiang , Yujie Chen, Gang Zhu, Hua Feng, Zhi Chen","doi":"10.1016/j.hest.2023.08.001","DOIUrl":"10.1016/j.hest.2023.08.001","url":null,"abstract":"<div><h3>Objective</h3><p>To investigate the efficacy and safety of MMA embolization in patients with CSDH who failed atorvastatin treatment.</p></div><div><h3>Methods</h3><p>Seventeen CSDH patients who failed atorvastatin treatment from Jan 1, 2021 to Dec 31, 2021 were included in the study. All patients were treated with MMA embolization using polyvinyl alcohol (PVA) particles.</p></div><div><h3>Results</h3><p>Twenty-six MMAs (unilateral embolization in 8 patients and bilateral embolization in 9 patients) were successfully embolized in all patients. Hematoma re-accumulated in only one patient (5.9%) after MMA embolization and was surgically evacuated. Procedural adverse events, mortality, or complications were not observed. At the last follow-up of an average of 51.5 days post MMA embolization, maximum hematoma thickness improved in 95.2% of CSDHs with a mean reduction of 52.1%, while mRS score improved in 94.1% of patients. In addition, 5 (29.4%) patients with unilateral hematoma underwent bilateral MMA embolization and hematoma absorbed completely in all 5 cases.</p></div><div><h3>Conclusions</h3><p>MMA embolization may be a minimally invasive alternative to surgical evacuation for CSDH patients resistant to atorvastatin. In unilateral CSDH, bilateral superselective angiography and bilateral MMA embolization could be a useful and effective treatment strategy.</p></div>","PeriodicalId":33969,"journal":{"name":"Brain Hemorrhages","volume":"4 4","pages":"Pages 195-200"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2589238X23000256/pdfft?md5=86fe51f29ccdedf16c784becaaddf3c6&pid=1-s2.0-S2589238X23000256-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75430274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brain HemorrhagesPub Date : 2023-12-01DOI: 10.1016/j.hest.2023.11.002
Iris Tang
{"title":"Call for papers: Special issue on brain aneurysms and subarachnoid hemorrhage","authors":"Iris Tang","doi":"10.1016/j.hest.2023.11.002","DOIUrl":"10.1016/j.hest.2023.11.002","url":null,"abstract":"","PeriodicalId":33969,"journal":{"name":"Brain Hemorrhages","volume":"4 4","pages":"Page 222"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2589238X23000463/pdfft?md5=3e72ca3405efb16ea0b98b74ca07fe45&pid=1-s2.0-S2589238X23000463-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135456548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brain HemorrhagesPub Date : 2023-12-01DOI: 10.1016/j.hest.2023.11.004
Iris Tang
{"title":"Special issue trailer: Clazosentan, first approval in Japan: Has perioperative management of subarachnoid hemorrhage changed?","authors":"Iris Tang","doi":"10.1016/j.hest.2023.11.004","DOIUrl":"10.1016/j.hest.2023.11.004","url":null,"abstract":"","PeriodicalId":33969,"journal":{"name":"Brain Hemorrhages","volume":"4 4","pages":"Pages 219-220"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2589238X23000487/pdfft?md5=d743a4519c27e0e9904c04b113a7769b&pid=1-s2.0-S2589238X23000487-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135564803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brain HemorrhagesPub Date : 2023-09-01DOI: 10.1016/j.hest.2023.03.001
Danyang Chen , Jinhua Yang , Robert P. Ostrowski , Yunjie Li , Yuxiong Wang , Zeyu Li , Yong Yang , Shiquan Li , Jieming Li , Simin Li , Yonghui Xiong , Shuisheng Rong , Chao Pan , Zhouping Tang
{"title":"Clinical study of CT-assisted positioning and bone marking-oriented transcerebellar aspiration of brainstem hemorrhage","authors":"Danyang Chen , Jinhua Yang , Robert P. Ostrowski , Yunjie Li , Yuxiong Wang , Zeyu Li , Yong Yang , Shiquan Li , Jieming Li , Simin Li , Yonghui Xiong , Shuisheng Rong , Chao Pan , Zhouping Tang","doi":"10.1016/j.hest.2023.03.001","DOIUrl":"https://doi.org/10.1016/j.hest.2023.03.001","url":null,"abstract":"<div><p>Sixty-three patients admitted to 5 hospitals in 2014–2020 for the treatment of severe hypertensive brainstem hemorrhage by CT-guided and bone marker-oriented transcerebellar aspiration were enrolled in this study. The puncture accuracy, duration of hematoma removal, tracheal decannulation, postoperative complications, postoperative consciousness recovery time, Glasgow Outcome Scale (GOS) score, and prognosis outcome at follow-up were retrospectively analyzed. Additionally, the relationship between admission Glasgow Coma Scale (GCS) score and GOS score, and between hematoma volume and prognosis of patients was analyzed at follow-up. Results showed that CT localization–based and bone marker oriented transcerebellar hematoma aspiration in the treatment of severe hypertensive brainstem hemorrhage ensures high puncture accuracy, relatively low surgery risk, and good prognosis. The prognosis relates to the state of consciousness and hematoma volume.</p></div>","PeriodicalId":33969,"journal":{"name":"Brain Hemorrhages","volume":"4 3","pages":"Pages 116-121"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49746185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Off-label use of Woven EndoBridge device in vertebro-basilar junction aneurysm and a review of the literature","authors":"Shail Thanki , Hannah Goldman-Daleo , Kunal Vakharia","doi":"10.1016/j.hest.2022.10.007","DOIUrl":"https://doi.org/10.1016/j.hest.2022.10.007","url":null,"abstract":"<div><p>An intrasaccular flow diverter, the Woven EndoBridge device has emerged as an alternate intervention for complex aneurysms of the ACA, MCA, ICA, and basilar artery. However, few studies report the use of the WEB device in off-label locations. This case report aims to contribute to this limited collection of data. We present a case of a 53-year-old male presenting with occipital headaches, found to have vertebrobasilar junction aneurysm. The WEB device was successfully used to embolize a large aneurysm of the vertebrobasilar junction, a current off-label location. This represents a new use of the WEB device, as well as an approach that addresses the limitations of other techniques used for vertebrobasilar junction aneurysms.</p></div>","PeriodicalId":33969,"journal":{"name":"Brain Hemorrhages","volume":"4 3","pages":"Pages 129-131"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49746187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}