ECMO治疗后凝血情况正常的COVID-19脑出血相关患者1例

IF 1.3 Q4 CLINICAL NEUROLOGY
Wael Osman Amer , Hussein Awad El gharieb , Hossam Ibrahim , Ahmed Alanazi , Mostafa Meshref
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引用次数: 4

摘要

目的2019冠状病毒病(coronavirus disease 2019,新冠肺炎)是一种新型冠状病毒引起的传染性急性呼吸道疾病,可发展为严重急性呼吸窘迫综合征(ARDS)。对于重症病例,体外膜肺氧合(ECMO)是一个很好的治疗选择。ECMO有许多副作用,包括出血。COVID患者可能发生脑出血,原因多种多样,包括新冠肺炎对ACE-2受体的影响,以及随后的高血压、凝血障碍、DIC或药物治疗,如抗凝药物的使用。病例介绍我们介绍一例53岁男性新冠肺炎患者,他在ECMO治疗后出现多发性、大量、严重的脑出血(ICH),尽管凝血情况正常。结论COVID-19可发展为严重急性呼吸窘迫综合征(ARDS),需要使用体外膜肺氧合(ECMO)。尽管ICH不是新冠肺炎疾病患者的常见并发症,但尚不清楚为什么该患者尽管具有正常的凝血特征,但ICH阈值较低。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Intracerebral hemorrhage associated COVID-19 patient with normal coagulation profile after ECMO treatment: A case report

Intracerebral hemorrhage associated COVID-19 patient with normal coagulation profile after ECMO treatment: A case report

Intracerebral hemorrhage associated COVID-19 patient with normal coagulation profile after ECMO treatment: A case report

Objective

Coronavirus disease 2019 (COVID-19) is a novel coronavirus-caused infectious acute respiratory disease that can progress to severe acute respiratory distress syndrome (ARDS). For severe cases, extracorporeal membrane oxygenation (ECMO) is an excellent treatment option. ECMO had a number of side effects, including bleeding. Intracerebral hemorrhage can occur in COVID patients due to a variety of mechanisms, including covid's effect on ACE-2 receptors and subsequent hypertension, coagulopathy, DIC, or medication, such as anticoagulant use.

Case presentation

We present a case of a 53-year-old male COVID-19 patient who developed multiple, massive, severe intracerebral hemorrhages (ICH) despite a normal coagulation profile after ECMO treatment.

Conclusion

COVID-19 can progress to severe acute respiratory distress syndrome (ARDS), necessitating the use of extracorporeal membrane oxygenation (ECMO). Although ICH is not a common complication in patients with COVID-19 disease, it is unknown why this patient had a lower threshold of ICH despite having a normal coagulation profile.

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来源期刊
Brain Hemorrhages
Brain Hemorrhages Medicine-Surgery
CiteScore
2.90
自引率
0.00%
发文量
52
审稿时长
22 days
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