Addiction and Health最新文献_第2页

Association of CREB1 (rs2253206) and BDNF (rs6265) Polymorphisms with Implementation Intentions Treatment Response in Smoking Reduction. CREB1 （rs2253206）和BDNF （rs6265）多态性与减少吸烟实施意向治疗反应的关系

Addiction and Health Pub Date : 2025-01-01 Epub Date: 2025-01-27 DOI: 10.34172/ahj.1502

Neda Yadegari, Mehdi Tehrani-Doost, Ali Yoonessi, Sareh Asadi, Reza Majdzadeh

{"title":"Association of CREB1 (rs2253206) and BDNF (rs6265) Polymorphisms with Implementation Intentions Treatment Response in Smoking Reduction.","authors":"Neda Yadegari, Mehdi Tehrani-Doost, Ali Yoonessi, Sareh Asadi, Reza Majdzadeh","doi":"10.34172/ahj.1502","DOIUrl":"10.34172/ahj.1502","url":null,"abstract":"Background: Previous studies have shown that implementation intentions are moderately effective in reducing smoking among smokers, but the factors determining its effectiveness are unclear. CREB1 (rs2253206) and BDNF (rs6265) polymorphisms have been proposed as the genes involved in addictive behaviors; therefore, we investigated their association with smokers' responses to implementation intentions psychotherapy.Methods: This clinical trial was conducted on smoking male students at Tehran University and Shahid Beheshti University. The research sample was 78 smoking students who smoked at least seven cigarettes weekly. All of the participants received an implementation intentions intervention session. Their smoking rates were measured before and after the intervention, and all of them were genotyped for CREB1 (rs2253206) and BDNF (rs6265) using PCR-RFLP. The prospective-retrospective memory questionnaire (PRMQ) was used to evaluate the prospective memory (PM). Analysis of covariance (ANCOVA) and simple linear regression were used to analyze the data using SPSS version 26 at a significance level of 0.05.Findings: The results showed that implementation intentions affect smoking reduction (t=4.44, P=0.001). Data analysis showed no relationship between these two SNPs and treatment response. Also, no association was observed between these SNPs and PM. However, regression analysis showed that PM could predict the response to treatment (R2=0.10, F=12.15, P=0.001).Conclusion: Implementation intentions can be suitable for reducing smoking. Studying the effect of genetic factors on psychotherapy in larger samples could be an effective way to individualize psychological treatments in reducing smoking, including implementation intentions.","PeriodicalId":33943,"journal":{"name":"Addiction and Health","volume":"17 ","pages":"1502"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12127981/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144209696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Transformation in the Psyche in the Congress 60: A Qualitative Study of Changes in Treatment Outcomes in Substance Use Disorders. 在大会上心理的转变60：物质使用障碍治疗结果变化的定性研究。

Addiction and Health Pub Date : 2025-01-01 Epub Date: 2025-06-28 DOI: 10.34172/ahj.1574

Ali Rashidian, Hamid Reza Khankeh, Ashraf Karbalaei Nouri, Omid Rezaei

{"title":"Transformation in the Psyche in the Congress 60: A Qualitative Study of Changes in Treatment Outcomes in Substance Use Disorders.","authors":"Ali Rashidian, Hamid Reza Khankeh, Ashraf Karbalaei Nouri, Omid Rezaei","doi":"10.34172/ahj.1574","DOIUrl":"10.34172/ahj.1574","url":null,"abstract":"Background: Congress 60, as an NGO, provides services to people with substance use disorders (SUDs). Despite offering services and evaluating their effectiveness in several studies, the underlying theory of interventions and the impact process of these interventions have not been investigated within this organization. The purpose of this study is to obtain the underlying theory of changes in treatment outcomes in this organization.Methods: To achieve this theory, the grounded theory methodology was used. The data for this study consisted of the results of in-depth individual interviews with 26 individuals treated at Congress 60 branches, as well as documents. The analysis of these data was conducted using continuous comparison analysis to extract concepts, involving open, axial, and selective coding. Trustworthiness was evaluated according to the grounded theory principles.Findings: The core concept derived from this study was the \"Theory of Transformations in the Psyche\" as presented in Congress 60. Subcategories of the core concept included the psyche, the addictive psyche, and the healthy psyche.Conclusion: In Congress 60, psyche is defined as the expression that a person shows, which is the interaction of physical structures and worldview. A person with SUD has an addictive psyche that is demonstrated in daily behavior and, therefore, experiences adverse outcomes. The person treated at Congress 60 achieves a healthy psyche, as shown in daily behavior, and thus experiences positive outcomes. The theory obtained in this study can explain the process of change in the outcomes in Congress 60.","PeriodicalId":33943,"journal":{"name":"Addiction and Health","volume":"17 ","pages":"1574"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12377689/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144972305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effectiveness of Digital Intervention for Tobacco Cessation Among Adults: A Systematic Review. 数字干预对成人戒烟的有效性：一项系统综述。

Addiction and Health Pub Date : 2025-01-01 Epub Date: 2025-03-29 DOI: 10.34172/ahj.1566

Milind Wasnik, Bhavna Dave, Virendra Vadher

{"title":"Effectiveness of Digital Intervention for Tobacco Cessation Among Adults: A Systematic Review.","authors":"Milind Wasnik, Bhavna Dave, Virendra Vadher","doi":"10.34172/ahj.1566","DOIUrl":"10.34172/ahj.1566","url":null,"abstract":"Background: The use of tobacco continues to pose a major public health issue worldwide, requiring effective cessation programs. Digital interventions present advantageous opportunities owing to their accessibility and scalability. This systematic review seeks to consolidate current research on the efficacy of digital interventions for tobacco cessation in adults.Methods: We performed a search utilizing pertinent keywords and databases. The search approach encompassed terms including \"digital interventions,\" \"smoking cessation,\" \"adults,\" and their permutations. Our primary focus was on academic databases including PubMed, EBSCO, Cochrane, and specialized journals pertaining to public health and smoking cessation. Search terms were limited to the English language exclusively. Databases from 2013 to 2023 were covered. Two writers independently collected data on cessation results and evaluated the likelihood of bias. A random effects meta-analysis was performed.Findings: Following the search, 305 articles were identified. After omitting 151 duplicates, 198 unique papers were analyzed. Of the 47 publications that underwent full-text examination, 8 were finally incorporated into this analysis. Subgroup analysis examined differences in intervention efficacy according to length, intervention type, and participant attributes.Conclusion: Digital treatments demonstrate the potential to facilitate smoke cessation in adults. Nonetheless, disparities in intervention design and participant attributes affect their efficacy. Additional studies are necessary to clarify effective intervention tactics and fill literature gaps, especially for long-term results and the scalability of digital therapies across varied populations.","PeriodicalId":33943,"journal":{"name":"Addiction and Health","volume":"17 ","pages":"1566"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12127979/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144209673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Effect of Opioid Use on Esophageal Cancer: A Systematic Review and Meta-analysis. 阿片类药物使用对食管癌的影响：系统回顾和荟萃分析。

Addiction and Health Pub Date : 2025-01-01 Epub Date: 2025-03-10 DOI: 10.34172/ahj.1533

Zahra Cheraghi, Nazanin Azmi-Naei, Mohadase Ameri, Bita Azmi-Naei

{"title":"The Effect of Opioid Use on Esophageal Cancer: A Systematic Review and Meta-analysis.","authors":"Zahra Cheraghi, Nazanin Azmi-Naei, Mohadase Ameri, Bita Azmi-Naei","doi":"10.34172/ahj.1533","DOIUrl":"10.34172/ahj.1533","url":null,"abstract":"Background: There is limited research available on the direct effect of opioid use on esophageal cancer. The objective of this systematic review and meta-analysis is to consolidate the results of previous studies and provide an estimate of the pooled relative risk or odds ratio associated with opioid use in relation to the occurrence of esophageal cancer.Methods: The PRISMA guidelines were utilized to establish a framework for conducting this systematic review and meta-analysis. A systematic search was conducted in international and national databases. PubMed, Web of Science, Scopus, and national electronic databases were searched up to February, 2024. The random-effects model was used to report the results at a 95% confidence interval (CI). Stata 11 was used for data analysis.Findings: Out of the 648 retrieved articles, 11 studies remained in the final analysis (one cohort study and ten case-control studies). In all subgroups analyzed based on the type of odds ratios, no significant heterogeneity was observed. The pooled adjusted odds ratio of opium on esophageal cancer was 1.8 (95% CI: 1.24-2.61), and the pooled crude odds ratio of opium on esophageal was 1.82 (95% CI: 1.55-2.14).Conclusion: The results of this systematic review and meta-analysis showed that there is a significant relationship between opium use and esophageal cancer, and opium can be a serious risk factor for esophageal cancer.","PeriodicalId":33943,"journal":{"name":"Addiction and Health","volume":"17 ","pages":"1533"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12127985/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144209676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Investigation of the Psychometric Properties of the Persian Version of the Functioning Assessment Short Test (FAST) in Bipolar Patients. 双相情感障碍患者波斯语版功能评估短测验（FAST）的心理测量特性研究。

Addiction and Health Pub Date : 2025-01-01 Epub Date: 2025-05-06 DOI: 10.34172/ahj.1663

Kiomars Najafi, Robabeh Soleimani, Mohammad Hasan Novin, Mohammad Abolghasemi Moghadam, Samin Khoshnoud Speily

{"title":"Investigation of the Psychometric Properties of the Persian Version of the Functioning Assessment Short Test (FAST) in Bipolar Patients.","authors":"Kiomars Najafi, Robabeh Soleimani, Mohammad Hasan Novin, Mohammad Abolghasemi Moghadam, Samin Khoshnoud Speily","doi":"10.34172/ahj.1663","DOIUrl":"10.34172/ahj.1663","url":null,"abstract":"Background: This study assessed the Persian version of the Functioning Assessment Short Test (FAST) in bipolar disorder patients to determine its reliability and validity, as currently no specialized tools are available to evaluate functional impairment in this population.Methods: A cross-sectional study was conducted with 240 bipolar disorder patients at Shafa Hospital in Rasht in 2023. The Persian version of the FAST was translated and reviewed for content validity, reliability, and factor analysis. Data analysis was done using IBM SPSS version 26, and confirmatory factor analysis (CFA) was performed with LISREL version 8.8.Findings: The results indicated a content validity ratio (CVR) above 0.62. To assess convergent validity, the Short Form Health Survey (SF-36) was used, yielding a direct and significant correlation (P<0.001, r=0.675). The FAST exhibited a Cronbach's alpha of 0.953, indicating robust internal consistency. The intraclass correlation coefficient (ICC) ranged from 0.74 to 0.98, signifying excellent reliability. The correlation coefficient between scores from repeated tests demonstrated strong reliability. CFA was employed to confirm the dimensions of the FAST, and the construct validity was considered satisfactory.Conclusion: The Persian version of the FAST demonstrated strong psychometric properties in the study, making it useful for evaluating rehabilitation interventions, assessing medication effects, and supporting research efforts.","PeriodicalId":33943,"journal":{"name":"Addiction and Health","volume":"17 ","pages":"1663"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12260922/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144643760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Methadone and the Kidney: Dissecting Gender Differences in Inflammation and Oxidative Stress Responses. 美沙酮和肾脏：在炎症和氧化应激反应中剖析性别差异。

Addiction and Health Pub Date : 2025-01-01 Epub Date: 2025-05-14 DOI: 10.34172/ahj.1625

Katayoon Kosari, Shadan Saberi, Hamid Najafipour, Zoya Tahergorabi, Elham Jafari, Saeideh Jafarinejad Farsangi

{"title":"Methadone and the Kidney: Dissecting Gender Differences in Inflammation and Oxidative Stress Responses.","authors":"Katayoon Kosari, Shadan Saberi, Hamid Najafipour, Zoya Tahergorabi, Elham Jafari, Saeideh Jafarinejad Farsangi","doi":"10.34172/ahj.1625","DOIUrl":"10.34172/ahj.1625","url":null,"abstract":"Background: This study explored the gender-specific effects of methadone, a synthetic opioid receptor agonist commonly used in opioid addiction treatment, on renal tissue and function. We aimed to elucidate the underlying mechanisms involving inflammatory pathways and redox system activity.Methods: Forty-two Wistar rats (200-250 g) were allocated into six groups: three males and three females, each comprised of control, and methadone-treated 5 mg/kg and 20 mg/kg. Over eight weeks, animals received either saline or methadone syrup orally. Blood urea nitrogen (BUN) and serum creatinine (sCr) were measured in serum. The inflammatory cytokines and antioxidant enzyme activity were assessed in left kidneys, which were preserved at -80 °C, while histopathological analysis via H&E staining was done on the formalin-fixed right kidneys.Findings: Methadone administration resulted in renal tissue injury characterized by enhanced glomerular and interstitial inflammation. Notable increases in malondialdehyde (MDA), BUN, sCr, transforming growth factor beta (TGF-β), tumor necrosis factor alpha (TNF-α), and interleukin 17 (IL-17) were observed in methadone-treated groups, indicating impaired renal function associated with oxidative stress and inflammation, with male rats exhibiting more severe alterations. Conversely, methadone treatment elevated glutathione peroxidase (GPx), and catalase (Cat) activities, predominantly in females.Conclusion: Prolonged methadone therapy exerts a nephrotoxic effect through the activation of oxidative stress and inflammatory pathways, with male rats displaying greater renal pathology and dysfunction, potentially attributed to diminished antioxidant defenses.","PeriodicalId":33943,"journal":{"name":"Addiction and Health","volume":"17 ","pages":"1625"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12260921/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144643761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Relationship Between Smokeless Tobacco and the Incidence of Oral Cancer: A Systematic Review Study. 无烟烟草与口腔癌发病率的关系：一项系统回顾研究。

Addiction and Health Pub Date : 2025-01-01 Epub Date: 2025-05-10 DOI: 10.34172/ahj.1522

Zohreh Dalirsani, Ala Ghazi, Atessa Pakfetrat, Jamshid Jamali, Zeinab Foroughi, Mohammad Mirzaei

{"title":"The Relationship Between Smokeless Tobacco and the Incidence of Oral Cancer: A Systematic Review Study.","authors":"Zohreh Dalirsani, Ala Ghazi, Atessa Pakfetrat, Jamshid Jamali, Zeinab Foroughi, Mohammad Mirzaei","doi":"10.34172/ahj.1522","DOIUrl":"10.34172/ahj.1522","url":null,"abstract":"Background: Many studies have examined the association between smokeless tobacco and the risk of oral cancer. In South and Southeastern Asia, the use of smokeless tobacco, which increases the risk of oral cancer, is very common. The aim of this study is to provide a comprehensive review of studies conducted and published in a period of ten years to provide a more accurate assessment of the association between smokeless tobacco and oral cancer.Methods: An electronic search in six databases (PubMed, Scopus, Embase, Web of Science, ProQuest, and Cochrane Library) was conducted using keywords equivalent to oral cancer and smokeless tobacco. After selecting the articles according to the inclusion and exclusion criteria, a total of 30 prospective cohort and case-control studies from 2010 to 2020, which investigated the association of smokeless tobacco with oral cancer, were examined. The articles were qualitatively assessed using the Newcastle Ottawa Quality Assessment scale checklist. Then, study design (study type, setting, and duration of data collection), sample population (number, gender, and age), cancer type, smokeless tobacco type, effect size, and confounder adjustment were extracted from the studies.Findings: Five studies examined smokeless tobacco and chewing tobacco, and 25 studies reported and evaluated the type of smokeless tobacco, most of which were related to betel quid and supari. While the results of 21 studies revealed a positive and significant relationship between oral cancer and smokeless tobacco use (OR: 0.67-149.5), seven studies did not find a significant correlation.Conclusion: This systematic review confirms the positive and significant association between non-smoking tobacco use and the risk of oral cancer.","PeriodicalId":33943,"journal":{"name":"Addiction and Health","volume":"17 ","pages":"1522"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12260923/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144643697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Seizures as an Adverse Effect of Pregabalin Consumption: A Systematic Review. 服用普瑞巴林对癫痫发作的不良影响：一项系统综述。

Addiction and Health Pub Date : 2025-01-01 Epub Date: 2025-02-08 DOI: 10.34172/ahj.1527

Zahra Oskouei, Mohammad Moshiri, Amene Raouf-Rahmati, Ahmad Nemati, Mehri Bemani Naeini, Hamid Jomehpour, Ali Roohbakhsh, Zahra Salmasi, Leila Etemad

{"title":"Seizures as an Adverse Effect of Pregabalin Consumption: A Systematic Review.","authors":"Zahra Oskouei, Mohammad Moshiri, Amene Raouf-Rahmati, Ahmad Nemati, Mehri Bemani Naeini, Hamid Jomehpour, Ali Roohbakhsh, Zahra Salmasi, Leila Etemad","doi":"10.34172/ahj.1527","DOIUrl":"10.34172/ahj.1527","url":null,"abstract":"Background: Pregabalin (PGB), a gabapantinoid drug, which is commonly prescribed by physicians and some patients abuse it, can lead to seizure. Pregabalin-induced seizures (PGBIS) and their risk factors were systematically reviewed.Methods: The databases were searched from January 1, 2011, to August 1, 2022. Studies that reported PGBIS were included. The records were assessed according to the PRISMA-P protocol.Findings: From a total of 224 records, 11 studies were included, comprising four cross-sectional studies and seven case reports. The data from the cross-sectional studies were notably limited. Seven studies documented nine cases (five females and four males), with a median age of 51 years (ranging from 16 to 65). PGB was used for therapeutic purposes, abuse, and suicide attempts. One case had kidney dysfunction. A significant number of cases used PGB with other drugs. There was no difference between the ingested dose of PGB in men (2700 and 4200 mg) and women (3000, 1200, 3825, and 1200 mg). All cases had normal renal function, except for one case.Conclusion: PGBIS is not common. However, it was reported for all purposes of PGB consumption. No specific risk factor for PGBIS was found. It was more commonly reported in females, patients who consumed high doses of PGB (>1200 mg), patients who ingested multiple drugs, and patients with renal insufficiency. The dosages used for therapeutic purposes were much lower than in the other two groups.","PeriodicalId":33943,"journal":{"name":"Addiction and Health","volume":"17 ","pages":"1527"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12128000/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144209675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Promoting Smoking in Iranian Movies: The Need for Cultural Strategies and Legal Reforms to Reduce Tobacco Consumption. 在伊朗电影中提倡吸烟：需要文化策略和法律改革来减少烟草消费。

Addiction and Health Pub Date : 2025-01-01 Epub Date: 2025-03-03 DOI: 10.34172/ahj.1661

Zahra Saboohi, Maryam Ghavami

引用次数: 0

Primal Prevention of Drug Abuse: An Emerging but Unrecognized Public Health Issue. 药物滥用的初步预防：一个新出现但未被认识到的公共卫生问题。

Addiction and Health Pub Date : 2025-01-01 Epub Date: 2025-04-21 DOI: 10.34172/ahj.1653

Nouzar Nakhaee

引用次数: 0