Medicine in Novel Technology and Devices最新文献_第8页

Effective techniques and emerging alternatives in orthodontic tooth movement: A systematic review 正畸牙齿移动的有效技术和新出现的替代方法:系统回顾

Medicine in Novel Technology and Devices Pub Date : 2023-11-10 DOI: 10.1016/j.medntd.2023.100274

Rushikesh Sangle , Manasvi Parab , Aditya Gujare , Pankaj Dhatrak , Sonali Deshmukh

{"title":"Effective techniques and emerging alternatives in orthodontic tooth movement: A systematic review","authors":"Rushikesh Sangle , Manasvi Parab , Aditya Gujare , Pankaj Dhatrak , Sonali Deshmukh","doi":"10.1016/j.medntd.2023.100274","DOIUrl":"10.1016/j.medntd.2023.100274","url":null,"abstract":"<div><p>Orthodontic procedures can be inconvenient in nature. To overcome this problem, accelerated orthodontics play a very important role to reduce existing trouble and discomfort. The most common inconvenience caused during orthodontic treatment procedures is that they are very time consuming which can result in several drawbacks, including an increased risk of tooth decay, gingival recession, and root resorption. Various methods can be employed to expedite orthodontic treatment by accelerating tooth movement, including surgical-assisted procedures, biological interventions, and the utilization of devices. These approaches effectively reduce the overall period of treatment. The purpose of this review is to study the effective techniques for orthodontic tooth movement as well as highlight various orthodontic accelerating methods in the respective approaches. Some non-surgical studies indicated that drug-induced methods can have a therapeutic effect on tooth movement. One of the approaches involves the local administration of Vitamin 1.25D, which has been found to expedite tooth movement. Vibrational orthodontic devices are a painless and cost-effective option that is considered the least invasive approach for accelerating tooth movement. Meanwhile, surgical approach is also a successful method, wherein great results and strong PDL tissue response were observed, but they cause a lot of pain and discomfort to the patient. Therefore, due to the strengths and limitations of each procedure covered in the study, more research should be done to identify the fastest way to speed up tooth mobility.</p></div>","PeriodicalId":33783,"journal":{"name":"Medicine in Novel Technology and Devices","volume":"20 ","pages":"Article 100274"},"PeriodicalIF":0.0,"publicationDate":"2023-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590093523000693/pdfft?md5=54b6f4c1e4d077020e1b930ef929875d&pid=1-s2.0-S2590093523000693-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135566574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Acupuncture for treating adolescent depression: Study protocol for a randomized controlled trial 针灸治疗青少年抑郁症:随机对照试验的研究方案

Medicine in Novel Technology and Devices Pub Date : 2023-11-08 DOI: 10.1016/j.medntd.2023.100273

Jinlan Jiang , Fengling Liang , Zitong Xu , Wei Jin , Baohua Ji , Lihong Li

{"title":"Acupuncture for treating adolescent depression: Study protocol for a randomized controlled trial","authors":"Jinlan Jiang , Fengling Liang , Zitong Xu , Wei Jin , Baohua Ji , Lihong Li","doi":"10.1016/j.medntd.2023.100273","DOIUrl":"https://doi.org/10.1016/j.medntd.2023.100273","url":null,"abstract":"<div><p>The prevalence of depression among adolescents has been significantly increasing in recent years. However, current antidepressants for adolescents have limited safety and efficacy. Acupuncture has been shown to be effective in treating depression in adults, but there is a lack of high-quality evidence for its effect on the treatment of adolescent depression, and the underlying mechanism is still unclear. Therefore, we designed a randomized controlled trial to explore the effectiveness and the therapeutic mechanisms of acupuncture on adolescent depression. This study will be designed as a multi-center, sham and randomized controlled clinical trial. For this purpose, a total of 96 adolescent depression patients diagnosed with moderate and severe depression will be randomly divided into the manual acupuncture group and the sham one, respectively. The two groups received acupuncture treatment 3 times a week for a total course lasting 4 weeks. All patients will be assessed according to the primary outcomes including Beck Depression Inventory-II (BDI-II), Hamilton Depression Rating Scale (HAMD-24) and Zung self-rating depression scale (SDS) at baseline, week 2, 4 and 8. Additionally, the secondary outcomes will be assessed at baseline and week 4, which includes intestinal flora structure, fecal short chain fatty acids (SCFAs) content and serum serotonin (5-HT) level. This study is the first randomized trial of acupuncture treatment of adolescent depression.</p></div><div><h3>Trial registration</h3><p>Chinese Clinical Trial Registry, ChiCTR2200064359. Registered on October 4, 2022.</p></div>","PeriodicalId":33783,"journal":{"name":"Medicine in Novel Technology and Devices","volume":"20 ","pages":"Article 100273"},"PeriodicalIF":0.0,"publicationDate":"2023-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590093523000681/pdfft?md5=07243dd4c18ea019de27ea5d647b50e8&pid=1-s2.0-S2590093523000681-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134656234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A computer vision-approach for activity recognition and residential monitoring of elderly people 老年人活动识别与居住监测的计算机视觉方法

Medicine in Novel Technology and Devices Pub Date : 2023-11-07 DOI: 10.1016/j.medntd.2023.100272

Sudhir Gaikwad , Shripad Bhatlawande , Swati Shilaskar , Anjali Solanke

{"title":"A computer vision-approach for activity recognition and residential monitoring of elderly people","authors":"Sudhir Gaikwad , Shripad Bhatlawande , Swati Shilaskar , Anjali Solanke","doi":"10.1016/j.medntd.2023.100272","DOIUrl":"10.1016/j.medntd.2023.100272","url":null,"abstract":"<div><p>In this study, we explore a human activity recognition (HAR) system using computer vision for assisted living systems (ALS). Most existing HAR systems are implemented using wired or wireless sensor networks. These systems have limitations such as cost, power issues, weight, and the inability of the elderly to wear and carry them comfortably. These issues could be overcome by a computer vision based HAR system. But such systems require a highly memory-consuming image dataset. Training such a dataset takes a long time. The proposed computer-vision-based system overcomes the shortcomings of existing systems. The authors have used key-joint angles, distances between the key joints, and slopes between the key joints to create a numerical dataset instead of an image dataset. All these parameters in the dataset are recorded via real-time event simulation. The data set has 780,000 calculated feature values from 20,000 images. This dataset is used to train and detect five different human postures. These are sitting, standing, walking, lying, and falling. The implementation encompasses four distinct algorithms: the decision tree (DT), random forest (RF), support vector machine (SVM), and an ensemble approach. Remarkably, the ensemble technique exhibited exceptional performance metrics with 99 % accuracy, 98 % precision, 97 % recall, and an F1 score of 99 %.</p></div>","PeriodicalId":33783,"journal":{"name":"Medicine in Novel Technology and Devices","volume":"20 ","pages":"Article 100272"},"PeriodicalIF":0.0,"publicationDate":"2023-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S259009352300067X/pdfft?md5=d53618fe6ac4153f8e4bb0c416a9bf0b&pid=1-s2.0-S259009352300067X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135510579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Identifying potential compounds from Bacopa monnieri (brahmi) against coxsackievirus A16 RdRp targeting HFM disease (tomato flu) 鉴定假马尾草抗柯萨奇病毒A16 RdRp(番茄流感)的潜在化合物

Medicine in Novel Technology and Devices Pub Date : 2023-11-01 DOI: 10.1016/j.medntd.2023.100270

Parveen Punia , Arun Prajapati , Priyasha Maitra , Avinash Mishra

{"title":"Identifying potential compounds from Bacopa monnieri (brahmi) against coxsackievirus A16 RdRp targeting HFM disease (tomato flu)","authors":"Parveen Punia , Arun Prajapati , Priyasha Maitra , Avinash Mishra","doi":"10.1016/j.medntd.2023.100270","DOIUrl":"https://doi.org/10.1016/j.medntd.2023.100270","url":null,"abstract":"<div><p>Hand, foot, and mouth disease (HFMD), primarily instigated by Coxsackievirus A16 (CVA16), poses a serious health concern, necessitating effective therapeutic interventions. The RNA-dependent RNA polymerase (RdRp) of CVA16 emerges as a promising drug target for HFMD treatment. This study presents an <em>in-silico</em> pipeline for the identification of potential RdRp inhibitors against CVA16. A library of 91 natural compounds derived from <em>Bacopa monnieri</em> (brahmi) was virtually screened against the CVA16 RdRp. Here, Bacobitacin D emerged as a promising hit molecule, forming 8 hydrogen bonds including key catalytic site residues (Asp<sup>238</sup> and Asp<sup>329</sup>) within the RdRp active site. Further, molecular dynamics (MD) simulations and MM/GBSA binding free energy calculations was applied on the top three hits that were selected based on exhaustive docking scores (≤−9.55 kcal/mol). Bacobitacin D exhibited sustainable stability, as evidenced by minimal deviation (RMSD = 0.75 ± 0.02 nm) during a 100 ns MD simulation. Importantly, Bacopaside IV exhibited the lowest ΔG<sub>TOTAL</sub> binding free energy (−23.70 kcal/mol), while Bacobitacin D displayed a comparable ΔG<sub>TOTAL</sub> of −19.14 kcal/mol. Structural interpretation of the most populated cluster derived from MD simulations showed direct interactions of Bacobitacin D with pivotal catalytic residues, including Asp<sup>238</sup> and Ser<sup>289</sup>. This comprehensive study confirmed Bacobitacin D as a potent inhibitor of CVA16 RdRp, offering a potential avenue for therapeutic intervention against HFMD. Experimental validation is required to confirm the inhibitory action of Bacobitacin D against HFMD<strong>.</strong></p></div>","PeriodicalId":33783,"journal":{"name":"Medicine in Novel Technology and Devices","volume":"20 ","pages":"Article 100270"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590093523000656/pdfft?md5=439ebfd4d047fe74b9a33a238494b70a&pid=1-s2.0-S2590093523000656-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91964454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Application of ensemble models approach in anemia detection using images of the palpable palm 集合模型方法在可触掌图像贫血检测中的应用

Medicine in Novel Technology and Devices Pub Date : 2023-10-31 DOI: 10.1016/j.medntd.2023.100269

Peter Appiahene , Samuel Segun Dzifa Dogbe , Emmanuel Edem Yaw Kobina , Philip Sackey Dartey , Stephen Afrifa , Emmanuel Timmy Donkoh , Justice Williams Asare

{"title":"Application of ensemble models approach in anemia detection using images of the palpable palm","authors":"Peter Appiahene , Samuel Segun Dzifa Dogbe , Emmanuel Edem Yaw Kobina , Philip Sackey Dartey , Stephen Afrifa , Emmanuel Timmy Donkoh , Justice Williams Asare","doi":"10.1016/j.medntd.2023.100269","DOIUrl":"https://doi.org/10.1016/j.medntd.2023.100269","url":null,"abstract":"<div><p>Anemia is a public health issue with serious ramifications for human health globally. Anemia particularly affects pregnant women and children from 6 to 59 months old even though every individual is at risk. Anemia occurs when the Hb level is below its normal threshold or when the red blood cells are weakened or destroyed. To discover medical remedies on time, early detection or diagnosis of anemia assist patients to understand their condition.</p><p>The invasive approach for anemia detection is costive and time-consuming as compared to the non-invasive approach which is reliable and suitable for developing communities where medical resources and personnel are inadequate. This study uses palpable palm images (dataset) collected from 710 participants in selected hospitals in Ghana. The images were extracted, segmented and converted into RGB percentile to train, validate and tested the machine learning models. A hybrid model was developed with the application of ensemble learning models using the R programming language on the R Studio platform. Stacking, voting, boosting and bagging ensemble model techniques were used to build the hybrid models, the stacking ensemble model achieved an accuracy of 99.73 %. The study justifies that ensemble models are efficient for medical disease diagnosis or detection such as anemia.</p></div>","PeriodicalId":33783,"journal":{"name":"Medicine in Novel Technology and Devices","volume":"20 ","pages":"Article 100269"},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590093523000644/pdfft?md5=e110653a3fba4f41bd8ab8b33eb066cc&pid=1-s2.0-S2590093523000644-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"92117020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of the antenna slot numbers and position on the performance of microwave ablation 天线槽数和位置对微波消融性能的影响

Medicine in Novel Technology and Devices Pub Date : 2023-10-31 DOI: 10.1016/j.medntd.2023.100271

Sabiha Binte Aziz , Md Rejvi Kaysir , Md Jahirul Islam , Torikul Islam , Mahmudur Rahman

{"title":"Effect of the antenna slot numbers and position on the performance of microwave ablation","authors":"Sabiha Binte Aziz , Md Rejvi Kaysir , Md Jahirul Islam , Torikul Islam , Mahmudur Rahman","doi":"10.1016/j.medntd.2023.100271","DOIUrl":"https://doi.org/10.1016/j.medntd.2023.100271","url":null,"abstract":"<div><p>Microwave ablation (MWA) is a type of thermal ablation used for cancer treatment in interventional radiology. To induce localized tissue heating MWA employs electromagnetic waves within the microwave energy spectrum, which is done by the precisely designed antenna. This study substantially emphasizes the design and performance ameliorating of slot (both single and double) antennae and compares the results with conventional monopole antennae in terms of temperature distribution, specific absorption ratio (SAR), and thermal tissue damage rate. The simulation has been done in COMSOL by solving the Bioheat equation along with Maxwell electromagnetic equations using the finite element method. The simulation results reveal that the double-slot antenna has the most accurate and directional heat dissipation for liver tumors as well as the highest tissue damage rate and SAR. The highest SAR was found to be 3500 W/kg and 3350 W/kg at the implant depth of 61 mm and 63 mm for double and single-slot antennae, respectively. In addition, the fastest tissue damage occurred near the upper slot of the double-slot antenna. This study helps to understand the basic design parameters for enhancing single and double-slot antennae performance.</p></div>","PeriodicalId":33783,"journal":{"name":"Medicine in Novel Technology and Devices","volume":"20 ","pages":"Article 100271"},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590093523000668/pdfft?md5=8d879373efbb66aeebbecb921c47da4d&pid=1-s2.0-S2590093523000668-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91964453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

MCSTransWnet: A new deep learning process for postoperative corneal topography prediction based on raw multimodal data from the Pentacam HR system MCSTransWnet：基于 Pentacam HR 系统原始多模态数据的术后角膜地形图预测深度学习新流程

Medicine in Novel Technology and Devices Pub Date : 2023-10-06 DOI: 10.1016/j.medntd.2023.100267

Nan Cheng , Zhe Zhang , Jing Pan , Xiao-Na Li , Wei-Yi Chen , Guang-Hua Zhang , Wei-Hua Yang

{"title":"MCSTransWnet: A new deep learning process for postoperative corneal topography prediction based on raw multimodal data from the Pentacam HR system","authors":"Nan Cheng , Zhe Zhang , Jing Pan , Xiao-Na Li , Wei-Yi Chen , Guang-Hua Zhang , Wei-Hua Yang","doi":"10.1016/j.medntd.2023.100267","DOIUrl":"10.1016/j.medntd.2023.100267","url":null,"abstract":"<div><p>This work provides a new multimodal fusion generative adversarial net (GAN) model, Multiple Conditions Transform W-net (MCSTransWnet), which primarily uses femtosecond laser arcuate keratotomy surgical parameters and preoperative corneal topography to predict postoperative corneal topography in astigmatism-corrected patients. The MCSTransWnet model comprises a generator and a discriminator, and the generator is composed of two sub-generators. The first sub-generator extracts features using the U-net model, vision transform (ViT) and a multi-parameter conditional module branch. The second sub-generator uses a U-net network for further image denoising. The discriminator uses the pixel discriminator in Pix2Pix. Currently, most GAN models are convolutional neural networks; however, due to their feature extraction locality, it is difficult to comprehend the relationships among global features. Thus, we added a vision Transform network as the model branch to extract the global features. It is normally difficult to train the transformer, and image noise and geometric information loss are likely. Hence, we adopted the standard U-net fusion scheme and transform network as the generator, so that global features, local features, and rich image details could be obtained simultaneously. Our experimental results clearly demonstrate that MCSTransWnet successfully predicts postoperative corneal topographies (structural similarity = 0.765, peak signal-to-noise ratio = 16.012, and Fréchet inception distance = 9.264). Using this technique to obtain the rough shape of the postoperative corneal topography in advance gives clinicians more references and guides changes to surgical planning and improves the success rate of surgery.</p></div>","PeriodicalId":33783,"journal":{"name":"Medicine in Novel Technology and Devices","volume":"21 ","pages":"Article 100267"},"PeriodicalIF":0.0,"publicationDate":"2023-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590093523000620/pdfft?md5=412058a35f3f2c21895df898f0a2d018&pid=1-s2.0-S2590093523000620-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135568495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

3D pulmonary vessel segmentation based on improved residual attention u-net 基于改进的残差注意力u-net的三维肺血管分割

Medicine in Novel Technology and Devices Pub Date : 2023-10-05 DOI: 10.1016/j.medntd.2023.100268

Jiachen Han , Naixin He , Qiang Zheng , Lin Li , Chaoqing Ma

引用次数: 0

Enhancing Parkinson's disease severity assessment through voice-based wavelet scattering, optimized model selection, and weighted majority voting 通过基于语音的小波散射、优化模型选择和加权多数投票增强帕金森病严重程度评估

Medicine in Novel Technology and Devices Pub Date : 2023-10-03 DOI: 10.1016/j.medntd.2023.100266

Farhad Abedinzadeh Torghabeh , Seyyed Abed Hosseini , Elham Ahmadi Moghadam

{"title":"Enhancing Parkinson's disease severity assessment through voice-based wavelet scattering, optimized model selection, and weighted majority voting","authors":"Farhad Abedinzadeh Torghabeh , Seyyed Abed Hosseini , Elham Ahmadi Moghadam","doi":"10.1016/j.medntd.2023.100266","DOIUrl":"https://doi.org/10.1016/j.medntd.2023.100266","url":null,"abstract":"<div><p>Parkinson's disease (PD) is a neurodegenerative disorder characterized by motor and non-motor symptoms that significantly impact an individual's quality of life. Voice changes have shown promise as early indicators of PD, making voice analysis a valuable tool for early detection and intervention. This study aims to assess and detect the severity of PD through voice analysis using the mobile device voice recordings dataset. The dataset consisted of recordings from PD patients at different stages of the disease and healthy control subjects. A novel approach was employed, incorporating a voice activity detection algorithm for speech segmentation and the wavelet scattering transform for feature extraction. A Bayesian optimization technique is used to fine-tune the hyperparameters of seven commonly used classifiers to optimize the performance of machine learning classifiers for PD severity detection. AdaBoost and K-nearest neighbor consistently demonstrated superior performance across various evaluation metrics among the classifiers. Furthermore, a weighted majority voting (WMV) technique is implemented, leveraging the predictions of multiple models to achieve a near-perfect accuracy of 98.62%, improving classification accuracy. The results highlight the promising potential of voice analysis in PD diagnosis and monitoring. Integrating advanced signal processing techniques and machine learning models provides reliable and accessible tools for PD assessment, facilitating early intervention and improving patient outcomes. This study contributes to the field by demonstrating the effectiveness of the proposed methodology and the significant role of WMV in enhancing classification accuracy for PD severity detection.</p></div>","PeriodicalId":33783,"journal":{"name":"Medicine in Novel Technology and Devices","volume":"20 ","pages":"Article 100266"},"PeriodicalIF":0.0,"publicationDate":"2023-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50175813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Numerical analysis of hemodynamic parameters in stenosed arteries under pulsatile flow conditions 脉动流条件下狭窄动脉血流动力学参数的数值分析

Medicine in Novel Technology and Devices Pub Date : 2023-09-29 DOI: 10.1016/j.medntd.2023.100265

Priyambada Praharaj , Chandrakant Sonawane , Anand Pandey , Vikas Kumar , Arundhati Warke , Hitesh Panchal , R. Ibrahim , Chander Prakash

{"title":"Numerical analysis of hemodynamic parameters in stenosed arteries under pulsatile flow conditions","authors":"Priyambada Praharaj , Chandrakant Sonawane , Anand Pandey , Vikas Kumar , Arundhati Warke , Hitesh Panchal , R. Ibrahim , Chander Prakash","doi":"10.1016/j.medntd.2023.100265","DOIUrl":"https://doi.org/10.1016/j.medntd.2023.100265","url":null,"abstract":"<div><p>This research studies the changes in flow patterns and hemodynamic parameters of diverse shapes and sizes of stenosis. Six different shapes and sizes of stenosis are constructed to investigate the variations in hemodynamics as the morphology changes. Changes in shape (trapezoidal and bell-shaped) and sizes of stenosis change the stresses on the walls and their flow patterns. TAWSS and OSI results specify that trapezoidal stenosis exerts greater stress than bell-shaped stenosis. Also, as the length of the trapezoidal stenosis increases, the TAWSS increases, whereas the trend is the opposite for bell-shaped stenosis. Later, this paper also studies different degrees of stenosis extracted from real images. Changes in velocity flow patterns, wall shear stress (WSS), Time-averaged wall shear stress (TAWSS) and Oscillatory shear index (OSI) have been studied for these images. Results illustrate that the peak velocity rises drastically as the stenosis percentage increases. Negative velocity is seen close to the artery's walls, indicating flow separation. This flow separation region is seen throughout the cycle except in the accelerating flow region. An increase in stenosis also increases WSS and TAWSS drastically. Negative WSS is seen downstream of stenosis, indicating flow recirculation. Such negative WSS in the blood vessels also promotes endothelial dysfunction. OSI values greater than 0.2 are seen near the stenosis region, indicating atherosclerosis growth. Regions of high OSI and low TAWSS are also identified, indicating probable regions of plaque development.</p></div>","PeriodicalId":33783,"journal":{"name":"Medicine in Novel Technology and Devices","volume":"20 ","pages":"Article 100265"},"PeriodicalIF":0.0,"publicationDate":"2023-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50175609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0