Medicine in Novel Technology and Devices最新文献_第10页

Application of ensemble models approach in anemia detection using images of the palpable palm 集合模型方法在可触掌图像贫血检测中的应用

Medicine in Novel Technology and Devices Pub Date : 2023-10-31 DOI: 10.1016/j.medntd.2023.100269

Peter Appiahene , Samuel Segun Dzifa Dogbe , Emmanuel Edem Yaw Kobina , Philip Sackey Dartey , Stephen Afrifa , Emmanuel Timmy Donkoh , Justice Williams Asare

{"title":"Application of ensemble models approach in anemia detection using images of the palpable palm","authors":"Peter Appiahene , Samuel Segun Dzifa Dogbe , Emmanuel Edem Yaw Kobina , Philip Sackey Dartey , Stephen Afrifa , Emmanuel Timmy Donkoh , Justice Williams Asare","doi":"10.1016/j.medntd.2023.100269","DOIUrl":"https://doi.org/10.1016/j.medntd.2023.100269","url":null,"abstract":"<div><p>Anemia is a public health issue with serious ramifications for human health globally. Anemia particularly affects pregnant women and children from 6 to 59 months old even though every individual is at risk. Anemia occurs when the Hb level is below its normal threshold or when the red blood cells are weakened or destroyed. To discover medical remedies on time, early detection or diagnosis of anemia assist patients to understand their condition.</p><p>The invasive approach for anemia detection is costive and time-consuming as compared to the non-invasive approach which is reliable and suitable for developing communities where medical resources and personnel are inadequate. This study uses palpable palm images (dataset) collected from 710 participants in selected hospitals in Ghana. The images were extracted, segmented and converted into RGB percentile to train, validate and tested the machine learning models. A hybrid model was developed with the application of ensemble learning models using the R programming language on the R Studio platform. Stacking, voting, boosting and bagging ensemble model techniques were used to build the hybrid models, the stacking ensemble model achieved an accuracy of 99.73 %. The study justifies that ensemble models are efficient for medical disease diagnosis or detection such as anemia.</p></div>","PeriodicalId":33783,"journal":{"name":"Medicine in Novel Technology and Devices","volume":"20 ","pages":"Article 100269"},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590093523000644/pdfft?md5=e110653a3fba4f41bd8ab8b33eb066cc&pid=1-s2.0-S2590093523000644-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"92117020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of the antenna slot numbers and position on the performance of microwave ablation 天线槽数和位置对微波消融性能的影响

Medicine in Novel Technology and Devices Pub Date : 2023-10-31 DOI: 10.1016/j.medntd.2023.100271

Sabiha Binte Aziz , Md Rejvi Kaysir , Md Jahirul Islam , Torikul Islam , Mahmudur Rahman

{"title":"Effect of the antenna slot numbers and position on the performance of microwave ablation","authors":"Sabiha Binte Aziz , Md Rejvi Kaysir , Md Jahirul Islam , Torikul Islam , Mahmudur Rahman","doi":"10.1016/j.medntd.2023.100271","DOIUrl":"https://doi.org/10.1016/j.medntd.2023.100271","url":null,"abstract":"<div><p>Microwave ablation (MWA) is a type of thermal ablation used for cancer treatment in interventional radiology. To induce localized tissue heating MWA employs electromagnetic waves within the microwave energy spectrum, which is done by the precisely designed antenna. This study substantially emphasizes the design and performance ameliorating of slot (both single and double) antennae and compares the results with conventional monopole antennae in terms of temperature distribution, specific absorption ratio (SAR), and thermal tissue damage rate. The simulation has been done in COMSOL by solving the Bioheat equation along with Maxwell electromagnetic equations using the finite element method. The simulation results reveal that the double-slot antenna has the most accurate and directional heat dissipation for liver tumors as well as the highest tissue damage rate and SAR. The highest SAR was found to be 3500 W/kg and 3350 W/kg at the implant depth of 61 mm and 63 mm for double and single-slot antennae, respectively. In addition, the fastest tissue damage occurred near the upper slot of the double-slot antenna. This study helps to understand the basic design parameters for enhancing single and double-slot antennae performance.</p></div>","PeriodicalId":33783,"journal":{"name":"Medicine in Novel Technology and Devices","volume":"20 ","pages":"Article 100271"},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590093523000668/pdfft?md5=8d879373efbb66aeebbecb921c47da4d&pid=1-s2.0-S2590093523000668-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91964453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

MCSTransWnet: A new deep learning process for postoperative corneal topography prediction based on raw multimodal data from the Pentacam HR system MCSTransWnet：基于 Pentacam HR 系统原始多模态数据的术后角膜地形图预测深度学习新流程

Medicine in Novel Technology and Devices Pub Date : 2023-10-06 DOI: 10.1016/j.medntd.2023.100267

Nan Cheng , Zhe Zhang , Jing Pan , Xiao-Na Li , Wei-Yi Chen , Guang-Hua Zhang , Wei-Hua Yang

{"title":"MCSTransWnet: A new deep learning process for postoperative corneal topography prediction based on raw multimodal data from the Pentacam HR system","authors":"Nan Cheng , Zhe Zhang , Jing Pan , Xiao-Na Li , Wei-Yi Chen , Guang-Hua Zhang , Wei-Hua Yang","doi":"10.1016/j.medntd.2023.100267","DOIUrl":"10.1016/j.medntd.2023.100267","url":null,"abstract":"<div><p>This work provides a new multimodal fusion generative adversarial net (GAN) model, Multiple Conditions Transform W-net (MCSTransWnet), which primarily uses femtosecond laser arcuate keratotomy surgical parameters and preoperative corneal topography to predict postoperative corneal topography in astigmatism-corrected patients. The MCSTransWnet model comprises a generator and a discriminator, and the generator is composed of two sub-generators. The first sub-generator extracts features using the U-net model, vision transform (ViT) and a multi-parameter conditional module branch. The second sub-generator uses a U-net network for further image denoising. The discriminator uses the pixel discriminator in Pix2Pix. Currently, most GAN models are convolutional neural networks; however, due to their feature extraction locality, it is difficult to comprehend the relationships among global features. Thus, we added a vision Transform network as the model branch to extract the global features. It is normally difficult to train the transformer, and image noise and geometric information loss are likely. Hence, we adopted the standard U-net fusion scheme and transform network as the generator, so that global features, local features, and rich image details could be obtained simultaneously. Our experimental results clearly demonstrate that MCSTransWnet successfully predicts postoperative corneal topographies (structural similarity = 0.765, peak signal-to-noise ratio = 16.012, and Fréchet inception distance = 9.264). Using this technique to obtain the rough shape of the postoperative corneal topography in advance gives clinicians more references and guides changes to surgical planning and improves the success rate of surgery.</p></div>","PeriodicalId":33783,"journal":{"name":"Medicine in Novel Technology and Devices","volume":"21 ","pages":"Article 100267"},"PeriodicalIF":0.0,"publicationDate":"2023-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2590093523000620/pdfft?md5=412058a35f3f2c21895df898f0a2d018&pid=1-s2.0-S2590093523000620-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135568495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

3D pulmonary vessel segmentation based on improved residual attention u-net 基于改进的残差注意力u-net的三维肺血管分割

Medicine in Novel Technology and Devices Pub Date : 2023-10-05 DOI: 10.1016/j.medntd.2023.100268

Jiachen Han , Naixin He , Qiang Zheng , Lin Li , Chaoqing Ma

引用次数: 0

Enhancing Parkinson's disease severity assessment through voice-based wavelet scattering, optimized model selection, and weighted majority voting 通过基于语音的小波散射、优化模型选择和加权多数投票增强帕金森病严重程度评估

Medicine in Novel Technology and Devices Pub Date : 2023-10-03 DOI: 10.1016/j.medntd.2023.100266

Farhad Abedinzadeh Torghabeh , Seyyed Abed Hosseini , Elham Ahmadi Moghadam

{"title":"Enhancing Parkinson's disease severity assessment through voice-based wavelet scattering, optimized model selection, and weighted majority voting","authors":"Farhad Abedinzadeh Torghabeh , Seyyed Abed Hosseini , Elham Ahmadi Moghadam","doi":"10.1016/j.medntd.2023.100266","DOIUrl":"https://doi.org/10.1016/j.medntd.2023.100266","url":null,"abstract":"<div><p>Parkinson's disease (PD) is a neurodegenerative disorder characterized by motor and non-motor symptoms that significantly impact an individual's quality of life. Voice changes have shown promise as early indicators of PD, making voice analysis a valuable tool for early detection and intervention. This study aims to assess and detect the severity of PD through voice analysis using the mobile device voice recordings dataset. The dataset consisted of recordings from PD patients at different stages of the disease and healthy control subjects. A novel approach was employed, incorporating a voice activity detection algorithm for speech segmentation and the wavelet scattering transform for feature extraction. A Bayesian optimization technique is used to fine-tune the hyperparameters of seven commonly used classifiers to optimize the performance of machine learning classifiers for PD severity detection. AdaBoost and K-nearest neighbor consistently demonstrated superior performance across various evaluation metrics among the classifiers. Furthermore, a weighted majority voting (WMV) technique is implemented, leveraging the predictions of multiple models to achieve a near-perfect accuracy of 98.62%, improving classification accuracy. The results highlight the promising potential of voice analysis in PD diagnosis and monitoring. Integrating advanced signal processing techniques and machine learning models provides reliable and accessible tools for PD assessment, facilitating early intervention and improving patient outcomes. This study contributes to the field by demonstrating the effectiveness of the proposed methodology and the significant role of WMV in enhancing classification accuracy for PD severity detection.</p></div>","PeriodicalId":33783,"journal":{"name":"Medicine in Novel Technology and Devices","volume":"20 ","pages":"Article 100266"},"PeriodicalIF":0.0,"publicationDate":"2023-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50175813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Numerical analysis of hemodynamic parameters in stenosed arteries under pulsatile flow conditions 脉动流条件下狭窄动脉血流动力学参数的数值分析

Medicine in Novel Technology and Devices Pub Date : 2023-09-29 DOI: 10.1016/j.medntd.2023.100265

Priyambada Praharaj , Chandrakant Sonawane , Anand Pandey , Vikas Kumar , Arundhati Warke , Hitesh Panchal , R. Ibrahim , Chander Prakash

{"title":"Numerical analysis of hemodynamic parameters in stenosed arteries under pulsatile flow conditions","authors":"Priyambada Praharaj , Chandrakant Sonawane , Anand Pandey , Vikas Kumar , Arundhati Warke , Hitesh Panchal , R. Ibrahim , Chander Prakash","doi":"10.1016/j.medntd.2023.100265","DOIUrl":"https://doi.org/10.1016/j.medntd.2023.100265","url":null,"abstract":"<div><p>This research studies the changes in flow patterns and hemodynamic parameters of diverse shapes and sizes of stenosis. Six different shapes and sizes of stenosis are constructed to investigate the variations in hemodynamics as the morphology changes. Changes in shape (trapezoidal and bell-shaped) and sizes of stenosis change the stresses on the walls and their flow patterns. TAWSS and OSI results specify that trapezoidal stenosis exerts greater stress than bell-shaped stenosis. Also, as the length of the trapezoidal stenosis increases, the TAWSS increases, whereas the trend is the opposite for bell-shaped stenosis. Later, this paper also studies different degrees of stenosis extracted from real images. Changes in velocity flow patterns, wall shear stress (WSS), Time-averaged wall shear stress (TAWSS) and Oscillatory shear index (OSI) have been studied for these images. Results illustrate that the peak velocity rises drastically as the stenosis percentage increases. Negative velocity is seen close to the artery's walls, indicating flow separation. This flow separation region is seen throughout the cycle except in the accelerating flow region. An increase in stenosis also increases WSS and TAWSS drastically. Negative WSS is seen downstream of stenosis, indicating flow recirculation. Such negative WSS in the blood vessels also promotes endothelial dysfunction. OSI values greater than 0.2 are seen near the stenosis region, indicating atherosclerosis growth. Regions of high OSI and low TAWSS are also identified, indicating probable regions of plaque development.</p></div>","PeriodicalId":33783,"journal":{"name":"Medicine in Novel Technology and Devices","volume":"20 ","pages":"Article 100265"},"PeriodicalIF":0.0,"publicationDate":"2023-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50175609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Design of polysaccharide gum based network copolymeric hydrogels for drug delivery and wound dressing applications 用于药物递送和伤口敷料应用的基于多糖胶的网络共聚水凝胶的设计

Medicine in Novel Technology and Devices Pub Date : 2023-09-20 DOI: 10.1016/j.medntd.2023.100262

Baljit Singh, Rajender Kumar, Sushil Kumar, Nistha Thakur, Kaka Ram

{"title":"Design of polysaccharide gum based network copolymeric hydrogels for drug delivery and wound dressing applications","authors":"Baljit Singh, Rajender Kumar, Sushil Kumar, Nistha Thakur, Kaka Ram","doi":"10.1016/j.medntd.2023.100262","DOIUrl":"https://doi.org/10.1016/j.medntd.2023.100262","url":null,"abstract":"<div><p>This article deals with the exploration of the design of network crosslinked structure by covalent bonding for use as wound dressing materials keeping in view inherent therapeutic role of neem gum in wound healing. These copolymeric hydrogels were prepared by graft-copolymerization reaction of carbopol and poly (<em>N</em>-vinylpyrrolidone) (poly (NVP). Antibiotic drug levofloxacin was encapsulated in dressings for better wound healing. The scanning electron microscopy (SEM), atomic force microscopy (AFM), Fourier transform infrared (FTIR) spectroscopy, <sup>13</sup>C nuclear magnetic resonance (NMR) spectroscopy, X-ray diffraction (XRD), thermogravimetric analysis (TGA), differential thermal gravimetry (DTG), and differential scanning calorimetry (DSC) techniques were applied for characterization. NMR and FTIR demonstrated incorporation of carbapol and poly (NVP) in dressings. XRD indicated amorphous state in copolymeric dressings. Interactions of copolymers with drug, blood and bio membrane were studied to evaluate biomedical properties which revealed controlled release of drug from hydrogel dressings which were possessing blood-compatible (haemolytic value = 2.45 ± 0.82) and mucoadhesive (detachment force = 124 ± 41 mN) properties. Dressings were permeable to O<sub>2</sub> and H<sub>2</sub>O vapour and absorbed 6.68 ± 0.62 g/g wound fluid which is ideal dressing characteristic. Diffusion mechanism type of drug levofloxacin was Fickian with kinetic model First order. These properties suggested use of hydrogel material for wound dressing and drug delivery applications for better wound care management.</p></div>","PeriodicalId":33783,"journal":{"name":"Medicine in Novel Technology and Devices","volume":"20 ","pages":"Article 100262"},"PeriodicalIF":0.0,"publicationDate":"2023-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50175610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A review of surface electromyography applications for the jaw muscles characterization in rehabilitation and disorders diagnosis 表面肌电图在颌骨肌肉表征和疾病诊断中的应用综述

Medicine in Novel Technology and Devices Pub Date : 2023-09-09 DOI: 10.1016/j.medntd.2023.100261

Marzieh Allami Sanjani , Ehsan Tahami , Gelareh Veisi

引用次数: 0

Binding kinetics of ten small-molecule drug candidates on SARS-CoV-2 3CLpro revealed by biomolecular simulations 生物分子模拟揭示10种小分子候选药物与sars - cov - 23clpro的结合动力学

Medicine in Novel Technology and Devices Pub Date : 2023-09-02 DOI: 10.1016/j.medntd.2023.100257

Yifei Zhou, Xubo Lin

{"title":"Binding kinetics of ten small-molecule drug candidates on SARS-CoV-2 3CLpro revealed by biomolecular simulations","authors":"Yifei Zhou, Xubo Lin","doi":"10.1016/j.medntd.2023.100257","DOIUrl":"10.1016/j.medntd.2023.100257","url":null,"abstract":"<div><p>3CL protease (3CLpro) is the main protease (Mpro) found in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which cuts the coronavirus polyprotein at eleven conserved sites and is essential for the virus replication. Therefore, 3CLpro has been widely used as a promising drug target. Many small-molecule drug candidates targeting 3CLpro have been proposed to inhibit the virus replication. In this work, we aim to reveal detailed interactions between ten small candidate molecules with extensive attention and 3CLpro using molecular docking and molecular dynamics simulations. First, we identified the possible binding sites of these candidate molecules on 3CLpro via molecular docking. Then, a series of 100 ns all-atom molecular dynamics simulations of strongest binding modes were performed to further evaluate the dynamical interactions between the molecules and 3CLpro in detail. Last, the binding free energy of these molecules on 3CLpro was calculated using MM/PBSA calculation, where the contribution of key amino acids was highlighted. The binding kinetics revealed in this work may provide useful insights into the action mechanism and applicability of these small-molecule drug candidates.</p></div>","PeriodicalId":33783,"journal":{"name":"Medicine in Novel Technology and Devices","volume":"20 ","pages":"Article 100257"},"PeriodicalIF":0.0,"publicationDate":"2023-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42570454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recent advancements on novel approaches of insulin delivery 胰岛素递送新途径的最新进展

Medicine in Novel Technology and Devices Pub Date : 2023-09-01 DOI: 10.1016/j.medntd.2023.100253

Sandip Karmakar , Manas Bhowmik , Bibek Laha , Sreejan Manna

{"title":"Recent advancements on novel approaches of insulin delivery","authors":"Sandip Karmakar , Manas Bhowmik , Bibek Laha , Sreejan Manna","doi":"10.1016/j.medntd.2023.100253","DOIUrl":"10.1016/j.medntd.2023.100253","url":null,"abstract":"<div><p>A large number of populations are living with diabetes, which is the most common endocrine disorder which is classified into Type-I and Type-II diabetes. Diabetes is one of the listed diseases specified in Section 3 of the Drug and Magic Remedies Act, 1954, where advertisement of drugs for certain diseases has been prohibited. It can be managed or controlled with proper diagnosis and treatment and by changing food habits. In addition to therapy with oral hypoglycemic agents, patients are also given subcutaneous insulin injections which is traditionally used in diabetes therapy. This multi-dose injectable therapy has relatively low patient compliance. To avoid the associated drawbacks with this therapy, several other delivery techniques, including oral, buccal, rectal, transdermal and pulmonary routes were investigated for effective insulin delivery. Several novel techniques along with novel devices are discussed in this review. The recent development in insulin delivery and products going through various phases of clinical trials are focused here. This review enumerates how the investigation, recent technology, and developments in research played a pivotal role in the treatment of diabetes in near future with alternative, safe, and efficient insulin delivery.</p></div>","PeriodicalId":33783,"journal":{"name":"Medicine in Novel Technology and Devices","volume":"19 ","pages":"Article 100253"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46666428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0