Fujita Medical Journal最新文献_第5页

Examination of the lifestyle of head injury patients using the Frenchay Activities Index. 利用弗伦奇活动指数研究头部受伤患者的生活方式。

Fujita Medical Journal Pub Date : 2023-11-01 Epub Date: 2023-08-28 DOI: 10.20407/fmj.2022-036

Masayuki Yamada, Toshio Teranishi, Megumi Suzuki, Kei Ohtsuka, Mihoko Ito, Akiko Maeda, Yoshikiyo Kanada

{"title":"Examination of the lifestyle of head injury patients using the Frenchay Activities Index.","authors":"Masayuki Yamada, Toshio Teranishi, Megumi Suzuki, Kei Ohtsuka, Mihoko Ito, Akiko Maeda, Yoshikiyo Kanada","doi":"10.20407/fmj.2022-036","DOIUrl":"https://doi.org/10.20407/fmj.2022-036","url":null,"abstract":"Objectives: The purpose of this study was to capture the lifestyle characteristics of traumatic brain injury (TBI) patients by administering the Frenchay Activities Index (FAI), a self-assessment questionnaire used for assessing life-related activities, among TBI patients.Methods: This study was conducted using the revised FAI Self-Assessment Form, administering an interview-based questionnaire survey to TBI patients and healthy participants. The target group comprised 60 traumatic brain injury patients who had progressed from at least 1 year since the injury, with a comparison group of 788 healthy participants.Results: A comparison of FAI scores between TBI patients and healthy participants by questionnaire revealed that TBI patients exhibited significantly higher FAI scores than healthy participants for outdoor walking and transportation use (Mann-Whitney U test, P<0.01). A comparison by occupation revealed that TBI patients were significantly less among the unemployed and other categories (Mann-Whitney U test, P<0.01). For office workers, government employees, high school students, and college students, scores were higher among TBI patients compared with healthy participants, although the differences were not significant.Conclusions: Although TBI patients were less active than healthy participants in life-related activities, their scores for cleaning up after meals and cleaning and putting things in order were close to those of healthy participants, indicating that TBI patients cannot be considered to be inactive. The findings also revealed differences in TBI patients' engagement in life-related activities and frequency of activities depending on their social position.","PeriodicalId":33657,"journal":{"name":"Fujita Medical Journal","volume":"9 4","pages":"282-287"},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10701225/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138810737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Review of the health-promoting effects of exercise and the involvement of myokines. 运动对健康的促进作用及肌因子的参与综述。

Fujita Medical Journal Pub Date : 2023-08-01 DOI: 10.20407/fmj.2022-020

Kazuhiro Nishii, Naoki Aizu, Kouji Yamada

{"title":"Review of the health-promoting effects of exercise and the involvement of myokines.","authors":"Kazuhiro Nishii, Naoki Aizu, Kouji Yamada","doi":"10.20407/fmj.2022-020","DOIUrl":"https://doi.org/10.20407/fmj.2022-020","url":null,"abstract":"Exercise reduces the risk of obesity-based, lifestyle-related diseases, such as metabolic abnormalities and cardiovascular diseases. The present review covers the health-promoting effects of exercise from the point of view of the physiologically active factor myokine, which is secreted by skeletal muscle, and focuses on the skeletal muscle as a new endocrine organ. Myokines have various effects, such as preventing metabolic syndrome by breaking down fat, preventing diabetes by improving glucose metabolism, and preventing progression of arteriosclerosis, dementia, and osteoporosis by enhancing bone metabolism. These substances also stabilize blood pressure, prevent cancer, increase immunity against infections, and prevent the development of age-associated diseases. Myokines are secreted by skeletal muscle into blood vessels, allowing them to exert systemic endocrine effects in organs throughout the body. Myokines are involved in bodily homeostasis and adaptation to the environment, and function by a mechanism similar to that of the skeletal muscle mass regulatory mechanism. Determining the relationships between multiple organs and their biological significance is important for exercise and health research. Progress in this field is expected to result in the identification of pathological mechanisms of action, development of new drugs, evaluation of the effectiveness of biomarkers over a wide range, and future improvement in healthcare.","PeriodicalId":33657,"journal":{"name":"Fujita Medical Journal","volume":"9 3","pages":"171-178"},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10405897/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9956767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

A clinicopathological analysis of forkhead box A1 (FOXA1) and estrogen receptor alpha expression in extramammary Paget's disease. 乳腺外佩吉特病叉头盒A1 (FOXA1)与雌激素受体α表达的临床病理分析

Fujita Medical Journal Pub Date : 2023-08-01 DOI: 10.20407/fmj.2022-030

Chiho Sumitomo, Yohei Iwata, Masaru Arima, Kazumitsu Sugiura

{"title":"A clinicopathological analysis of forkhead box A1 (FOXA1) and estrogen receptor alpha expression in extramammary Paget's disease.","authors":"Chiho Sumitomo, Yohei Iwata, Masaru Arima, Kazumitsu Sugiura","doi":"10.20407/fmj.2022-030","DOIUrl":"https://doi.org/10.20407/fmj.2022-030","url":null,"abstract":"Objectives: Extramammary Paget's disease (EMPD) is a neoplastic skin disease of unknown etiology. EMPD is frequently associated with forkhead box A1 (FOXA1) expression, which correlates with the expression of estrogen receptor alpha (ER). FOXA1 regulates the transcriptional activity of ER and may function cooperatively in the tumorigenesis of breast cancer.Methods: We performed immunohistochemical staining for FOXA1 and ER using tissue samples from 16 patients with EMPD.Results: The nuclei of Paget cells isolated from each of the 16 patients with EMPD (100%) were strongly FOXA1-positive, and the FOXA1 staining intensity was similar across all samples. ER staining was detected in the nuclei of Paget cells originating from seven patients with EMPD (44%), and the ER staining intensity varied between these patients.Conclusions: In the present study, we confirmed that EMPD was frequently associated with FOXA1 expression. However, ER expression varied between patients and did not always coincide with FOXA1 expression. No clear relationship was observed between ER expression, the intensity of ER staining, or EMPD metastasis and prognosis. However, the results indicate that hormone-dependent cancer therapy may be effective in patients with ER-positive EMPD.","PeriodicalId":33657,"journal":{"name":"Fujita Medical Journal","volume":"9 3","pages":"236-239"},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10405903/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9963120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Factors influencing early obliteration during flow diverter treatment of cerebral aneurysms: Establishment of an early obliteration inhibition score. 脑动脉瘤分流治疗中影响早期闭塞的因素:早期闭塞抑制评分的建立。

Fujita Medical Journal Pub Date : 2023-08-01 DOI: 10.20407/fmj.2022-033

Akiko Hasebe, Ichiro Nakahara, Shoji Matsumoto, Jun Morioka, Jun Tanabe, Sadayoshi Watanabe, Kenichiro Suyama, Takuma Ishihara, Yuichi Hirose

{"title":"Factors influencing early obliteration during flow diverter treatment of cerebral aneurysms: Establishment of an early obliteration inhibition score.","authors":"Akiko Hasebe, Ichiro Nakahara, Shoji Matsumoto, Jun Morioka, Jun Tanabe, Sadayoshi Watanabe, Kenichiro Suyama, Takuma Ishihara, Yuichi Hirose","doi":"10.20407/fmj.2022-033","DOIUrl":"https://doi.org/10.20407/fmj.2022-033","url":null,"abstract":"Objective: This retrospective study aimed to investigate factors associated with inhibition of early aneurysm obliteration after flow diverter (FD) treatment. We also created the early obliteration inhibition (EOI) score for pre-operative evaluation.Methods: We examined 110 cerebral aneurysms in 104 patients who underwent FD treatment. The following parameters were investigated: age, sex, symptoms, aneurysm location and type, maximum aneurysm diameter, parent vessel diameter, neck diameter, and dome-neck ratio. We also noted aneurysm location relative to the curvature of the parent artery and any branches arising from the aneurysm dome. Procedural factors such as FD diameter and length, number of FDs placed, type of FD, and use of adjunctive coiling were also investigated. Aneurysm obliteration was evaluated using digital subtraction angiography 3 months after the procedure. Adequate obliteration was defined as grade C or D on the O'Kelly-Marotta scale.Results: The following factors inhibited early obliteration: 1) extradural location, 2) saccular aneurysm, 3) aneurysm neck located at the outer convexity of the parent artery, and 4) arterial branch arising from the aneurysm dome. Odds ratios were used to create an EOI score. Receiver operating characteristic curve analysis showed that the optimal cut-off EOI score for adequate obliteration was 1.5 (area under the curve, 0.81; 95% confidence interval, 0.73-0.9; sensitivity, 0.9; specificity, 0.57).Conclusion: The EOI score, which is based on factors that inhibit early obliteration, may predict early treatment outcomes of FD placement.","PeriodicalId":33657,"journal":{"name":"Fujita Medical Journal","volume":"9 3","pages":"240-245"},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10405891/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9968632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fujita Medical Journal Pub Date : 2023-08-01 DOI: 10.20407/fmj.2022-039

Yasuko Enya, Hiroyuki Hiramatsu, Masaru Ihira, Ryota Suzuki, Yuki Higashimoto, Yusuke Funato, Kei Kozawa, Hiroki Miura, Masafumi Miyata, Yoshiki Kawamura, Takuma Ishihara, Koki Taniguchi, Satoshi Komoto, Tetsushi Yoshikawa

{"title":"Similarities in rotavirus vaccine viral shedding and immune responses in pairs of twins.","authors":"Yasuko Enya, Hiroyuki Hiramatsu, Masaru Ihira, Ryota Suzuki, Yuki Higashimoto, Yusuke Funato, Kei Kozawa, Hiroki Miura, Masafumi Miyata, Yoshiki Kawamura, Takuma Ishihara, Koki Taniguchi, Satoshi Komoto, Tetsushi Yoshikawa","doi":"10.20407/fmj.2022-039","DOIUrl":"https://doi.org/10.20407/fmj.2022-039","url":null,"abstract":"Objectives: Intestinal rotavirus (RV) vaccine replication and host immune response are suggested to be affected by several factors, including maternal antibodies, breastfeeding history, and gut microbiome, which are thought to be similar in pairs of twins. The aim of this study was to determine whether viral shedding from the fecal RV vaccine strain Rotarix® (RV1) and IgG and IgA responses to RV show similarity in pairs of twins.Methods: Quantitative reverse transcription polymerase chain reaction specific to RV vaccine strain RV1 was used to monitor fecal RV1 viral shedding. RV IgG and IgA titers were measured using an in-house enzyme-linked immunosorbent assay. Fecal RV1 viral shedding and immune responses were compared between twins and singletons with mixed effects and fixed effects models.Results: A total of 347 stool and 54 blood samples were collected from four pairs of twins and twelve singletons during the observation period. Although the kinetics of fecal RV1 viral shedding and immune responses differed among vaccinated individuals, they appeared to be similar within twin pairs. RV shedding after the first dose (P=0.049) and RV IgG titers during the entire observation period (P=0.015) had a significantly better fit in the fixed effect model that assumed that twins have the same response versus the model that assumed that twins have a different response.Conclusions: The similarity of RV vaccine viral replication in intestine and host immune responses in twin pairs was demonstrated using statistical analysis.","PeriodicalId":33657,"journal":{"name":"Fujita Medical Journal","volume":"9 3","pages":"253-258"},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10405898/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9956768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Subjective assessment of brexpiprazole in patients with schizophrenia: a prospective observational study. brexpiprazole在精神分裂症患者中的主观评价:一项前瞻性观察性研究。

Fujita Medical Journal Pub Date : 2023-08-01 DOI: 10.20407/fmj.2022-031

Rina Yokoi, Masakazu Hatano, Hiroyuki Kamei, Aoi Morita, Manako Hanya, Nakao Iwata, Shigeki Yamada

{"title":"Subjective assessment of brexpiprazole in patients with schizophrenia: a prospective observational study.","authors":"Rina Yokoi, Masakazu Hatano, Hiroyuki Kamei, Aoi Morita, Manako Hanya, Nakao Iwata, Shigeki Yamada","doi":"10.20407/fmj.2022-031","DOIUrl":"https://doi.org/10.20407/fmj.2022-031","url":null,"abstract":"Objectives: To investigate the subjective assessments of an antipsychotic treatment with brexpiprazole.Methods: This was a 14-week prospective observational study. Nineteen patients participated in the study between February 2019 and January 2020.Results: Patients had a mean age of 40.6±14.2 years and a Clinical Global Impressions-Severity of Illness scale (CGI-S) score of 4.6±1.2 at the initiation of brexpiprazole treatment. The Subjective Well-being under Neuroleptic drug treatment Short form, Japanese version (SWNS-J) total score significantly improved from 68.1±22.3 in week 2 to 79.5±21.0 in week 14 (p=0.0084). The SWNS-J subscales of self-control and social integration status also significantly improved from 14.0±4.7 and 13.9±6.0 in week 2 to 17.0±4.7 and 16.0±5.1 in week 14, respectively (p=0.0053 and 0.012, respectively). No significant improvements were observed in any other SWNS-J subscales or the Drug Attitude Inventory-10 (DAI-10) in the 14-week observation period. Moreover, the SWNS-J total score did not correlate with the DAI-10 (r=0.31, p=0.19), or CGI-S (r=-0.18, p=0.47) scores.Conclusions: The present results suggest that brexpiprazole might improve subjective well-being, although this may not necessarily reflect psychopathological improvements. To enhance medication adherence, it is important to perform subjective assessments on patients over time.","PeriodicalId":33657,"journal":{"name":"Fujita Medical Journal","volume":"9 3","pages":"231-235"},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10405899/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9963119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Preoperative detailed evaluation intracranial artery stenosis using three-dimensional visualization analysis reduces the invasiveness of superficial temporal artery-middle cerebral artery bypass. 术前应用三维可视化分析详细评价颅内动脉狭窄，减少颞浅动脉-大脑中动脉搭桥术的侵入性。

Fujita Medical Journal Pub Date : 2023-08-01 DOI: 10.20407/fmj.2022-022

Riki Tanaka, Fuminari Komatsu, Kento Sasaki, Kyosuke Miyatani, Yasuhiro Yamada, Yoko Kato, Yuichi Hirose

{"title":"Preoperative detailed evaluation intracranial artery stenosis using three-dimensional visualization analysis reduces the invasiveness of superficial temporal artery-middle cerebral artery bypass.","authors":"Riki Tanaka, Fuminari Komatsu, Kento Sasaki, Kyosuke Miyatani, Yasuhiro Yamada, Yoko Kato, Yuichi Hirose","doi":"10.20407/fmj.2022-022","DOIUrl":"https://doi.org/10.20407/fmj.2022-022","url":null,"abstract":"Objectives: Superficial temporal artery (STA) to middle cerebral artery (MCA) bypass surgery is a common treatment for preventing cerebral ischemia in patients with intracranial artery stenosis. The aim of this study was to analyze the surgical outcomes of the STA-MCA bypass procedure, particularly with regard to the invasiveness of targeted bypass (TB) with preoperative planning using Amira® software.Methods: Consecutive patients with single STA-MCA bypass performed by a single neurosurgeon from January 2019 to May 2022 were included. The clinical parameters of seven TB patients were compared with those of 11 patients treated with the conventional method (CM).Results: Compared with CM patients, TB using Amira® software patients had a shorter scalp incision (median [interquartile range]=11.2 [9.7-12.7] cm vs. 16.9 [16.0-17.7] cm, respectively; p=0.004], smaller craniotomy size (11.8 [11.5-14.4] cm2 vs. 20.9 [17.1-22.2] cm2, respectively; p=0.01], shorter surgery duration (201 [195-218] min vs. 277 [229-310] min, respectively; p=0.003], and less intraoperative bleeding (10 [10-20] g vs. 23 [20-50] g, respectively; p=0.033]. However, there were no differences in surgical complications between the two groups.Conclusions: Detailed preoperative evaluation using Amira® software can reduce the invasiveness of the STA-MCA bypass procedure.","PeriodicalId":33657,"journal":{"name":"Fujita Medical Journal","volume":"9 3","pages":"206-210"},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10405892/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9963121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of recombinant human soluble thrombomodulin on neutrophil extracellular traps in the kidney of a mouse model of endotoxin shock. 重组人可溶性血栓调节蛋白对内毒素休克小鼠肾脏中性粒细胞胞外陷阱的影响。

Fujita Medical Journal Pub Date : 2023-08-01 DOI: 10.20407/fmj.2022-026

Tatsuhiko Harada, Yasuyo Shimomura, Osamu Nishida, Munenori Maeda, Yu Kato, Tomoyuki Nakamura, Naohide Kuriyama, Hidefumi Komura

{"title":"Effects of recombinant human soluble thrombomodulin on neutrophil extracellular traps in the kidney of a mouse model of endotoxin shock.","authors":"Tatsuhiko Harada, Yasuyo Shimomura, Osamu Nishida, Munenori Maeda, Yu Kato, Tomoyuki Nakamura, Naohide Kuriyama, Hidefumi Komura","doi":"10.20407/fmj.2022-026","DOIUrl":"https://doi.org/10.20407/fmj.2022-026","url":null,"abstract":"Objectives: Sepsis is a life-threatening condition characterized by multi-organ dysfunction due to host immune system dysregulation in response to an infection. During sepsis, neutrophils release neutrophil extracellular traps (NETs) as part of the innate immune response. However, excessive NETs play a critical role in the development of organ failure during sepsis. Although recombinant human soluble thrombomodulin (rTM) can inhibit NET formation in the lungs and liver of a mouse model of endotoxin shock, its effects on the kidneys are unclear.Methods: The specific effects of NETs and rTM on the renal cortex and renal medulla were examined in a mouse model of endotoxin shock generated by intraperitoneal (i.p.) injection of lipopolysaccharide (LPS), followed by i.p. injection of rTM or an identical volume of saline 1 h later.Results: LPS injection increased serum creatinine, blood urea nitrogen, and histone H3 levels. However, rTM administration significantly decreased histone H3 and citrullinated histone H3 (citH3) levels. Immunohistochemical analysis revealed no significant changes in citH3 quantity in the renal cortex of any group. However, in the renal medulla, the increase in citH3 induced by LPS was abolished in the LPS+rTM group.Conclusions: Our findings demonstrate that rTM can suppress NETs in the renal medulla of mice with endotoxin-induced acute kidney injury.","PeriodicalId":33657,"journal":{"name":"Fujita Medical Journal","volume":"9 3","pages":"225-230"},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10405902/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9963122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A case of tracheotomy using the Ex Utero Intrapartum Treatment (EXIT) procedure in cooperation with multiple professions. 气管切开术采用宫内治疗(EXIT)程序在多专业合作。

Fujita Medical Journal Pub Date : 2023-08-01 DOI: 10.20407/fmj.2021-030

Yasunori Asai, Hisayuki Kato, Kanetaka Horibe, Yusuke Hiei, Ichiro Tateya

{"title":"A case of tracheotomy using the Ex Utero Intrapartum Treatment (EXIT) procedure in cooperation with multiple professions.","authors":"Yasunori Asai, Hisayuki Kato, Kanetaka Horibe, Yusuke Hiei, Ichiro Tateya","doi":"10.20407/fmj.2021-030","DOIUrl":"https://doi.org/10.20407/fmj.2021-030","url":null,"abstract":"In this study, we report a case of tracheotomy using the ex utero intrapartum treatment (EXIT) procedure in a fetus that was pointed out as having bilateral giant cervical cysts at prenatal diagnosis and whose postnatal airway occlusion was predicted. The subject was a female aged 35. She was diagnosed with polyhydramnios at 28 weeks of pregnancy. The fetus was found to have a giant cervical cyst before she was referred to the department of obstetrics and gynecology of our hospital. On the second day of 37 weeks of pregnancy, oral tracheal intubation was attempted on the fetus using the EXIT procedure after the caesarean operation, but intubation was difficult resulting in a tracheotomy. The oxygenation of the fetus during the operation was maintained well without any postoperative complication. Postnatal fetal airway occlusion is a critical incident which may lead to the death of a fetus. It was assumed, however, that the airway management under the same procedure was completed by the preoperative detailed simulation with the staff of the departments of anesthesiology, obstetrics and gynecology and pediatrics as well as the operating room personnel.","PeriodicalId":33657,"journal":{"name":"Fujita Medical Journal","volume":"9 3","pages":"259-263"},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10405901/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9968630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Geriatric nutritional risk index as readmission predictor in older adults with heart failure irrespective of ejection fraction. 老年营养风险指数作为老年心力衰竭患者再入院的预测指标，与射血分数无关。

Fujita Medical Journal Pub Date : 2023-08-01 DOI: 10.20407/fmj.2022-028

Yoshihiro Sato, Masahiro Kumada, Hideki Kawai, Sadako Motoyama, Masayoshi Sarai, Tsutomu Nakagawa, Hideo Izawa

{"title":"Geriatric nutritional risk index as readmission predictor in older adults with heart failure irrespective of ejection fraction.","authors":"Yoshihiro Sato, Masahiro Kumada, Hideki Kawai, Sadako Motoyama, Masayoshi Sarai, Tsutomu Nakagawa, Hideo Izawa","doi":"10.20407/fmj.2022-028","DOIUrl":"https://doi.org/10.20407/fmj.2022-028","url":null,"abstract":"Objectives: Malnutrition is associated with an increased risk of hospital readmission for heart failure in patients with acute decompensated heart failure (ADHF). Therefore, evaluation of the nutritional status in patients with ADHF may be important. The geriatric nutritional risk index (GNRI), the controlling nutritional status (CONUT) score, and the prognostic nutritional index (PNI) are widely used objective indexes for evaluation of the nutritional status. The present study was performed to determine the best nutritional index for predicting the prognosis in older adults with ADHF.Methods: We retrospectively studied 167 older adults (>65 years of age) who were admitted with ADHF from January 2012 to December 2015 and discharged alive. The objective nutritional status was evaluated using the GNRI, CONUT score, and PNI at admission. The endpoint of this study was unplanned hospitalization for worsening heart failure (WHF) within 1 year after discharge.Results: During the follow-up period, 58 patients were readmitted for WHF. In the multivariate Cox analysis, only the GNRI (p<0.0001) was independently associated with readmission for WHF among the three nutritional indexes. Kaplan-Meier analysis revealed that patients in the low-GNRI group (<90 as determined by receiver operating characteristic curve analysis) had a significantly greater risk of 1-year hospital readmission for WHF (p<0.0001; hazard ratio, 6.1; 95% confidence interval, 3.5-10.5).Conclusion: Among the objective nutritional indexes, the GNRI is the best predictor of readmission for WHF within 1 year after discharge in older adults with ADHF.","PeriodicalId":33657,"journal":{"name":"Fujita Medical Journal","volume":"9 3","pages":"211-217"},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10405900/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10338040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0