Sports Medicine and Health Science最新文献

{"title":"Effect of aerobic exercise on GRP78 and ATF6 expressions in mice with non-alcoholic fatty liver disease","authors":"Junhan Li ,&nbsp;Lei Huang ,&nbsp;Wei Xiong ,&nbsp;Chun Gu ,&nbsp;Shuling Zhang ,&nbsp;Xiali Xue","doi":"10.1016/j.smhs.2022.11.002","DOIUrl":"10.1016/j.smhs.2022.11.002","url":null,"abstract":"<div><p>Nonalcoholic fatty liver disease (NAFLD) is a prevalent medical condition with an ever-growing trend. Although multiple intracellular mechanisms are involved, endoplasmic reticulum (ER) stress has been demonstrated to play a significant role in the genesis and progression. Most of the research supports the advantages of exercise for NAFLD. However, little is known about the molecular mechanism(s) that underpin the effectiveness of exercise training in NAFLD. This study aimed to identify how aerobic exercise affected hepatic ER stress in a mouse NAFLD model. In this study, the mice were fed either a standard diet (SD) or a high-fat diet (HFD) for 17 weeks. HFD mice were trained on a treadmill during the last eight weeks. All animals were tested for serum levels of biochemical assays, protein expression, and gene expression. The hematoxylin and eosin, Oil red O, and immunohistochemistry staining were also performed. The results indicated that a high-fat diet generated NAFLD, with serum lipid disruption and hepatic function impairment, and increased GRP78 and ATF6 expressions. However, aerobic training reversed the majority of these alterations. It is concluded that NAFLD appears to be associated with hepatic ER stress response, and aerobic exercise mitigates NAFLD via lowering ER stress proteins GRP78 and ATF6.</p></div>","PeriodicalId":33620,"journal":{"name":"Sports Medicine and Health Science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10323921/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9864705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The burden of prolonged sedentary behavior imposed by uberization","authors":"Thalles Guilarducci Costa ,&nbsp;Vinnycius Nunes de Oliveira ,&nbsp;Douglas Assis Teles Santos ,&nbsp;Ricardo Borges Viana ,&nbsp;Marilia Santos Andrade ,&nbsp;Rodrigo Luiz Vancini ,&nbsp;Katja Weiss ,&nbsp;Beat Knechtle ,&nbsp;Claudio Andre Barbosa de Lira","doi":"10.1016/j.smhs.2023.02.005","DOIUrl":"10.1016/j.smhs.2023.02.005","url":null,"abstract":"<div><p>Mobility applications are rapidly growing in cities worldwide due to their convenience and low cost. Mobility applications drivers experience vast flexibility in work hours, often work longer than in fixed-hours jobs, and can constantly transport passengers in their vehicles for up to 12 h; after this, they must go offline for eight consecutive hours before driving again. Nonetheless, drivers have found an easy way around this limitation by switching to other apps and continuing driving. This burden of prolonged work can increase sedentary behavior among mobility applications drivers. Sedentary behavior is any waking activity in which the individual expends 1.5 metabolic equivalents (METs) or less while sitting or reclining. This behavior can increase the risk of detrimental effects on health. In this opinion article, we aim to discuss the possible effects of the burden of prolonged work on the sedentary behavior of mobility applications drivers and propose possible strategies to face this concerning situation.</p></div>","PeriodicalId":33620,"journal":{"name":"Sports Medicine and Health Science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a9/f1/main.PMC10323908.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9864706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Non-enzymatic antioxidant blood plasma profile in the period of high training loads of elite speed skaters in the altitude","authors":"Elena Proskurnina ,&nbsp;Dmitry Martynov ,&nbsp;Andrey Yakushkin ,&nbsp;Irina Zelenkova","doi":"10.1016/j.smhs.2023.02.002","DOIUrl":"10.1016/j.smhs.2023.02.002","url":null,"abstract":"<div><p>At the altitude, hypoxia and training load are key factors in the development of oxidative stress. Altitude-induced oxidative stress is developed due to the depletion of antioxidant potential. In the current study, we examined the non-enzymatic antioxidant profile of blood plasma in 7 males and 5 females specializing in speed skating at a 21-day training camp at 1 850 ​m above sea level. Training included: cycling, roller skating, ice skating, strength training, and special training. At the start point and the endpoint, total hemoglobin mass (tHb-mass), hemoglobin concentration, and circulating blood volume were determined. Antioxidant profiles, hypoxic doses, hypoxic impulses, and training impulses were assessed at 3, 6, 10, 14, and 18 days. Antioxidant profiles consisting of “urate” and “thiol” parts were registered with chemiluminometry. In the training dynamics, antioxidant parameters changed individually, but in total there was a decrease in the “urate” capacity by a factor of 1.6 (<em>p</em> ​= ​0.001) and an increase in the “thiol” capacity by a factor of 1.8 (<em>p</em> ​= ​0.013). The changes in “urate” capacity positively correlated (<em>r</em>_S ​= ​0.40) and the changes in “thiol” capacity negatively correlated (<em>r</em>_S ​= ​−0.45) with changes in tHb-mass. Both exercise and hypoxic factors affect the antioxidant parameters bidirectionally. They correlated with a decrease in thiol capacity and with an increase in urate capacity. The assessment of the non-enzymatic antioxidant profile can be a simple and useful addition to screening the reactive oxygen species homeostasis and can help choose the personalized training schedule, individualize recovery and ergogenic support.</p></div>","PeriodicalId":33620,"journal":{"name":"Sports Medicine and Health Science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10323913/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9864708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of overuse injury prevention programs on upper extremity performance in overhead youth athletes: A systematic review","authors":"Rachel Y. Lau,&nbsp;Swarup Mukherjee","doi":"10.1016/j.smhs.2023.03.001","DOIUrl":"10.1016/j.smhs.2023.03.001","url":null,"abstract":"<div><p>Several targeted upper extremity injury prevention programs have been developed to mitigate the risk of upper extremity overuse injuries among youth athletes in overhead sports; however, their effectiveness on performance outcome measures has not been investigated. This systematic review evaluated the effectiveness of existing upper extremity injury prevention programs that focused on modifying intrinsic risk factors, and performance outcome measures in overhead youth athletes. The secondary aim was to identify the training components of these programs. PubMed, Physiotherapy Evidence Database (PEDro), SPORTDiscus (via EBSCOhost), and Web of Science were searched from January 2000 to November 2020 for studies that implemented training programs or exercises for upper extremity injury prevention among youth athletes in overhead throwing or striking sports. An updated search was conducted from December 2020 to October 2022. A program was deemed effective for a performance outcome measure if significant improvements were observed in the intervention group as compared to the control group. Of the 1 394 studies identified, five studies met the inclusion criteria. The effectiveness of the injury prevention programs on the identified performance outcome measures of strength, mobility, and sport-specific measures were 30.4%, 28.6%, and 22.2%, respectively. The training components targeted were strength, mobility, and plyometrics. Strength was the most common training component and was also the most widely investigated performance outcome measure. Overall, current upper extremity injury prevention programs seem effective at improving performance outcome measures of strength, mobility, and sport-specific outcomes with training components of strength, mobility and plyometrics. Standardized protocols are required for the measurement and reporting of performance outcomes measures, and the reporting of training components.</p></div>","PeriodicalId":33620,"journal":{"name":"Sports Medicine and Health Science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10323919/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9864704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vitamin C and E supplementation and high intensity interval training induced changes in lipid profile and haematological variables of young males","authors":"Surojit Sarkar ,&nbsp;Swapan Kr Dey ,&nbsp;Gouriprosad Datta ,&nbsp;Amit Bandyopadhyay","doi":"10.1016/j.smhs.2023.03.006","DOIUrl":"10.1016/j.smhs.2023.03.006","url":null,"abstract":"<div><p>High intensity interval training (HIIT) causes oxidative stress and haematological alteration. Present study was aimed to evaluate the effect of 8 weeks’ supplementation of vitamin C and E on HIIT induced changes in lipid profile parameters and haematological variables. Hundred six male adolescent players were randomly assigned into five age-matched groups, i.e., Control (no exercise+placebo), HIIT (placebo), HIIT ​+ ​vitamin-C (1 000 ​mg/day), HIIT ​+ ​vitamin-E 400 IU/day) and combined HIIT ​+ ​vitamin C and E. Morning and evening sessions (90 ​min) of HIIT included 4 phases (15 ​min each) with 3 sets (4 ​min each). Each 4 ​min HIIT set consisted of 2 ​min intense sprint workout (90%–95% of heart rate maximum [HR_max]) followed by 1 ​min active recovery (60%–70% HR_max) followed by 1 ​min of complete rest (1:1 work-rest ratio). Lipid profile parameters, haematological variables, endurance capacity and vertical jump were evaluated by standard protocols. Significant decrease in body weight, fat%, total cholesterol, triglyceride, Total Cholesterol/High Density Lipoprotein-Cholesterol and significant increase in High Density Lipoprotein-Cholesterol, maximal oxygen consumption, vertical jump were observed for all four intervention groups. White blood cell count, red blood cell count, haemoglobin percentage and haematocrit values were significantly decreased while platelet count and platelet-to-leukocyte ratio (PLR) ratio were increased significantly only for HIIT group. Blood level of tocopherol and ascorbic acid was significantly increased (values were within the normal range) in all the respective vitamin supplemented groups. Supplementation of vitamin C and E secures health protection with suppressed haemolysis and improved inflammatory blood variables with enhanced explosive leg strength and lipid profile parameters without any concomitant change in endurance capacity.</p></div>","PeriodicalId":33620,"journal":{"name":"Sports Medicine and Health Science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10323915/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10167194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Athletes with mild post-COVID-19 symptoms experience increased respiratory and metabolic demands: Α cross-sectional study","authors":"Vasileios T. Stavrou ,&nbsp;Astara Kyriaki ,&nbsp;George D. Vavougios ,&nbsp;Ioannis G. Fatouros ,&nbsp;George S. Metsios ,&nbsp;Konstantinos Kalabakas ,&nbsp;Dimitrios Karagiannis ,&nbsp;Zoe Daniil ,&nbsp;Konstantinos I. Gourgoulianis ,&nbsp;George Βasdekis","doi":"10.1016/j.smhs.2022.10.004","DOIUrl":"10.1016/j.smhs.2022.10.004","url":null,"abstract":"<div><p>Coronavirus Disease 2019 (COVID-19) has significantly affected different physiological systems, with a potentially profound effect on athletic performance. However, to date, such an effect has been neither addressed nor investigated. Therefore, the aim of this study was to investigate fitness indicators, along with the respiratory and metabolic profile, in post-COVID-19 athletes. Forty male soccer players, were divided into two groups: non-hospitalized COVID-19 (<em>n</em> = 20, Age: [25.2 ± 4.1] years, Body Surface Area [BSA]: [1.9 ± 0.2] m², body fat: 11.8% ± 3.4%) versus [vs] healthy (<em>n</em> = 20, Age: [25.1 ± 4.4] years, BSA: [2.0 ± 0.3] m², body fat: 10.8% ± 4.5%). For each athlete, prior to cardiopulmonary exercise testing (CPET), body composition, spirometry, and lactate blood levels, were recorded. Differences between groups were assessed with the independent samples <em>t</em>-test (<em>p</em> &lt; 0.05). Several differences were detected between the two groups: ventilation (<span><math><mrow><msub><mover><mi>V</mi><mo>˙</mo></mover><mi>E</mi></msub></mrow></math></span>: Resting: [14.7 ± 3.1] L·min⁻¹ vs. [11.5 ± 2.6] L·min⁻¹, <em>p</em> = 0.001; Maximal Effort: [137.1 ± 15.5] L·min⁻¹ vs. [109.1 ± 18.4] L·min⁻¹, <em>p</em> &lt; 0.001), ratio V_E/maximal voluntary ventilation (Resting: 7.9% ± 1.8% vs. 5.7% ± 1.7%, <em>p</em> &lt; 0.001; Maximal Effort: 73.7% ± 10.8% vs. 63.1% ± 9.0%, <em>p</em> = 0.002), ratioV_E/BSA (Resting: 7.9% ± 2.0% vs. 5.9% ± 1.4%, <em>p</em> = 0.001; Maximal Effort: 73.7% ± 11.1% vs. 66.2% ± 9.2%, <em>p</em> = 0.026), heart rate (Maximal Effort: [191.6 ± 7.8] bpm vs. [196.6 ± 8.6] bpm, <em>p</em> = 0.041), and lactate acid (Resting: [1.8 ± 0.8] mmol·L^-1 vs. [0.9 ± 0.1] mmol·L^-1, <em>p</em> &lt; 0.001; Maximal Effort: [11.0 ± 1.6] mmol·L^-1 vs. [9.8 ± 1.2] mmol·L^-1, <em>p</em> = 0.009), during CPET. No significant differences were identified regarding maximal oxygen uptake ([55.7 ± 4.4] ml·min⁻¹·kg⁻¹ vs. [55.4 ± 4.6] ml·min⁻¹·kg⁻¹, <em>p</em> = 0.831). Our findings demonstrate a pattern of compromised respiratory function in post-COVID-19 athletes characterized by increased respiratory work at both rest and maximum effort as well as hyperventilation during exercise, which may explain the reported increased metabolic needs.</p></div>","PeriodicalId":33620,"journal":{"name":"Sports Medicine and Health Science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9595388/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9734650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of a cardiac telerehabilitation program during COVID-19 associated social isolation","authors":"","doi":"10.1016/j.smhs.2023.03.002","DOIUrl":"10.1016/j.smhs.2023.03.002","url":null,"abstract":"<div><p>This study aimed to compare the impact of a cardiac telerehabilitation (CTR) protocol aimed at patients with cardiovascular diseases (CVDs) during the period of coronavirus disease 2019 (COVID-19) associated with social isolation. This retrospective cohort study included 58 participants diagnosed with stable cardiovascular diseases (CVDs), which were divided into three groups: conventional cardiac rehabilitation (CCR) group (<em>n</em> ​= ​20), composed of patients undergoing conventional cardiac rehabilitation; cardiac telerehabilitation (CTR) group (<em>n</em> ​= ​18), composed of patients undergoing cardiac telerehabilitation and control group (<em>n</em> ​= ​20), composed of patients admitted for cardiac rehabilitation who had not started training programs. The results showed that body mass index was reduced (<em>p</em> ​= ​0.019) and quality of life was improved (e.g., limitations due to physical aspects [<em>p</em> ​= ​0.021), vitality [<em>p</em> ​= ​0.045] and limitations due to emotional aspects [<em>p</em> ​= ​0.024]) by CCR compared to baseline. These outcomes were not improved by CTR (<em>p</em> ​&gt; ​0.05). However, this strategy prevented clinical deterioration in the investigated patients. Although CCR achieved a superior effect on clinical improvement and quality of life, CTR was relevant to stabilize the blood pressure and quality of life of patients with cardiovascular diseases during the period of COVID-19-associated social isolation.</p></div>","PeriodicalId":33620,"journal":{"name":"Sports Medicine and Health Science","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10065809/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9714553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"More than a key—the pathological roles of SARS-CoV-2 spike protein in COVID-19 related cardiac injury","authors":"","doi":"10.1016/j.smhs.2023.03.004","DOIUrl":"10.1016/j.smhs.2023.03.004","url":null,"abstract":"<div><p>Cardiac injury is common in hospitalized coronavirus disease 2019 (COVID-19) patients and cardiac abnormalities have been observed in a significant number of recovered COVID-19 patients, portending long-term health issues for millions of infected individuals. To better understand how Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2, CoV-2 for short) damages the heart, it is critical to fully comprehend the biology of CoV-2 encoded proteins, each of which may play multiple pathological roles. For example, CoV-2 spike glycoprotein (CoV-2-S) not only engages angiotensin converting enzyme II (ACE2) to mediate virus infection but also directly activates immune responses. In this work, the goal is to review the known pathological roles of CoV-2-S in the cardiovascular system, thereby shedding lights on the pathogenesis of COVID-19 related cardiac injury.</p></div>","PeriodicalId":33620,"journal":{"name":"Sports Medicine and Health Science","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2023-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10062797/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9707625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Going nuclear: Molecular adaptations to exercise mediated by myonuclei","authors":"Pieter J. Koopmans ,&nbsp;Kevin A. Zwetsloot ,&nbsp;Kevin A. Murach","doi":"10.1016/j.smhs.2022.11.005","DOIUrl":"10.1016/j.smhs.2022.11.005","url":null,"abstract":"<div><p>Muscle fibers are multinucleated, and muscle fiber nuclei (myonuclei) are believed to be post-mitotic and are typically situated near the periphery of the myofiber. Due to the unique organization of muscle fibers and their nuclei, the cellular and molecular mechanisms regulating myofiber homeostasis in unstressed and stressed conditions (e.g., exercise) are unique. A key role myonuclei play in regulating muscle during exercise is gene transcription. Only recently have investigators had the capability to identify molecular changes at high resolution exclusively in myonuclei in response to perturbations <em>in vivo</em>. The purpose of this review is to describe how myonuclei modulate their transcriptome, epigenetic status, mobility and shape, and microRNA expression in response to exercise <em>in vivo</em>. Given the relative paucity of high-fidelity information on myonucleus-specific contributions to exercise adaptation, we identify specific gaps in knowledge and provide perspectives on future directions of research.</p></div>","PeriodicalId":33620,"journal":{"name":"Sports Medicine and Health Science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/96/ae/main.PMC10040379.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9213796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hot topics in muscle metabolism and adaptation","authors":"Zhen Yan,&nbsp;David A. Hood","doi":"10.1016/j.smhs.2023.01.004","DOIUrl":"10.1016/j.smhs.2023.01.004","url":null,"abstract":"","PeriodicalId":33620,"journal":{"name":"Sports Medicine and Health Science","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/1f/d9/main.PMC10040370.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9573201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}