Amritha S , Patel VK , Kuttippurath J , Varikoden Hamza
{"title":"The COVID-19 lockdown induced changes of SO2 pollution in its Human-made global hotspots","authors":"Amritha S , Patel VK , Kuttippurath J , Varikoden Hamza","doi":"10.1016/j.glt.2024.06.003","DOIUrl":"https://doi.org/10.1016/j.glt.2024.06.003","url":null,"abstract":"<div><p>Sulphur dioxide (SO<sub>2</sub>) is a hazardous air pollutant, which is mostly emitted from burning of fossil fuels, and has an adverse impact on the human health and ecosystem functioning. The COVID-19 natural anthropause (lockdown) provides a great opportunity to understand the changes in SO<sub>2</sub> pollution across the globe, as there was a temporary standstill for most human activities. Therefore, we analyse the changes in global SO₂ pollution during lockdown compared to pre-lockdown and identify its hotspots driven by human activities using satellite measurements, reanalysis data and emission inventory. We observe a decline in SO₂ pollution of about 2.21 % in its global average, −21.05 % in Indo-Gangatic Plain, −16 % in East China, −7.67 % in East United States of America, −3.99 % in Western Europe and −3.85 % in Middle East owing to the halt in human activities such as industrial and transport operations, as found from the emissions inventory. There are point and aerial hotspots of SO₂ pollution across the globe (e.g. cities or industrial units), which also show a decrease (20–30 %) in SO₂ pollution during the anthropause. Fossil fuel burning in thermal power plants is a major source of SO<sub>2</sub> pollution, and it has declined notably (1–12 %) during the lockdown in the major coal consuming countries such as the United States, China, Japan, Canada, Brazil, Australia, France, Germany, Spain, Italy and the United Kingdom. Therefore, lockdown provides a clear understanding of global human-driven hotspots of SO₂ pollution and their changes, which would help us to make better and effective air pollution mitigation strategies.</p></div>","PeriodicalId":33615,"journal":{"name":"Global Transitions","volume":"6 ","pages":"Pages 152-163"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2589791824000100/pdfft?md5=dfe5f245a54accc6cd970ea6767adce2&pid=1-s2.0-S2589791824000100-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141485059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Byomkesh Talukder , Nilanjana Ganguli , Eunice Choi , Mohammadali Tofighi , Gary W. vanloon , James Orbinski
{"title":"Exploring the nexus: Comparing and aligning Planetary Health, One Health, and EcoHealth","authors":"Byomkesh Talukder , Nilanjana Ganguli , Eunice Choi , Mohammadali Tofighi , Gary W. vanloon , James Orbinski","doi":"10.1016/j.glt.2023.12.002","DOIUrl":"https://doi.org/10.1016/j.glt.2023.12.002","url":null,"abstract":"<div><p>The interconnectedness between humans and ecosystems highlights the need to protect ecosystems for the well-being of humans and the environment. This has led to the emergence of holistic and interdisciplinary concepts like Planetary Health, One Health, and EcoHealth. There is a growing interest in the differences and implementation of these concepts, including their founders, fundamental questions answered, focus, global distribution of studies, and alignment. This study addresses these issues to facilitate coordinated health interventions for people and ecosystems. Using electronic databases (Web of Science, PubMed, and ProQuest) and conducting a systematic literature review using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA), this paper compares the concepts of Planetary Health, One Health, and EcoHealth, providing a comprehensive overview of the findings and insights by examining each field's advocacy, conceptual application, and implementation levels and exploring the contributions of influential individuals and organizations. The results highlight each concept's global relation to applicability, challenges, and opportunities for further advancement. The study concludes by emphasizing the shared goals and interconnections among these fields in addressing complex health issues at the nexus of human health, environmental health, and ecosystem well-being.</p></div>","PeriodicalId":33615,"journal":{"name":"Global Transitions","volume":"6 ","pages":"Pages 66-75"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2589791823000397/pdfft?md5=88552d360b7777fa38ba74e6aa8b4e9b&pid=1-s2.0-S2589791823000397-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139653652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Do the Olympics impact CO2 emissions? A cross-national analysis","authors":"Angelique Ceccon, Andrew Hargrove, Jamie Sommer","doi":"10.1016/j.glt.2024.10.003","DOIUrl":"10.1016/j.glt.2024.10.003","url":null,"abstract":"<div><div>In recent decades scholars and practitioners have grown concerned about the sustainability of mega sporting events, such as the Olympics. While there has been much debate concerning the carbon footprint of the Olympics, and attempts to manage CO2 emissions of the event in the future, there is little empirical research to our knowledge that puts the Olympics events in a cross-national context, which would enable us to assess how the Olympics, over time and compared to other countries, has impacted CO2 emissions cross-nationally, rather than as an isolated event. This is important because emissions from the Olympics are not just bound to the hosting nation but are more diffuse given the level of travel and trade customary to the event. Moreover, a cross-national quantitative approach can help us understand the overall impact of hosting the Olympics on CO2 emissions, which may provide a larger and longer perspective from which to critique and amend guidelines and principles surrounding such events. To do so, we use two-way fixed effects regression analysis for a sample of 131 nations from 1991 to 2019 to assess how the Olympics impacts CO2 emissions cross-nationally. We find that both in the two years preceding an Olympics event and in the year of the event CO2 emissions of the hosting nation are significantly increased, even while controlling for relevant factors such as GDP, population, trade, agriculture, and manufacturing. This impact is consistent across countries and across time. However, we also find that CO2 emissions do not remain increased once the event is finished. Our analysis shows that emissions in a nation return to pre-Olympics levels in the year following the event.</div></div>","PeriodicalId":33615,"journal":{"name":"Global Transitions","volume":"6 ","pages":"Pages 241-248"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142650924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Liangyu Kang , Jian Hu , Kangning Cai , Wenzhan Jing , Min Liu , Wannian Liang
{"title":"The Intelligent Infectious Disease Active Surveillance and early warning system in China: An application of dengue prevention and control","authors":"Liangyu Kang , Jian Hu , Kangning Cai , Wenzhan Jing , Min Liu , Wannian Liang","doi":"10.1016/j.glt.2024.10.004","DOIUrl":"10.1016/j.glt.2024.10.004","url":null,"abstract":"<div><div>Utilizing advanced information technologies such as big data and artificial intelligence (AI), China has established and implemented the Intelligent Infectious Disease Active Surveillance and Early Warning System. It provides new tools for the surveillance, early warning, and response to infectious diseases, enhancing the timeliness, scientific basis, and efficiency of epidemic control efforts. The system comprises four functional modules including multi-channel active surveillance, intelligent early warning, data-driven risk assessment, and smart emergency response. This paper provides a detailed overview of the structure and functions of the Intelligent Infectious Disease Active Surveillance and Early Warning System in China, with a specific focus on its application in dengue prevention and control in Hainan Province from February to May 2024. Firstly, the system can proactively capture and integrate heterogeneous surveillance data from multiple sources. Based on these multi-channel data, users can select appropriate warning indicators and AI models to automatically trigger early warnings. Using vast amounts of surveillance data, the system can construct machine learning models to accurately assess the transmission risk of infectious diseases. In terms of emergency response, the system offers powerful tools for early diagnosis, smart epidemiological investigation, digital contact tracing, vaccine and drug development, and evaluation of intervention measures. This system facilitates early detection, reporting, and management of outbreaks, serving as a valuable reference for other countries and regions. Nevertheless, continuous efforts are needed to strengthen scientific research and multidisciplinary collaboration, establish reliable data collection mechanisms, enhance continuous model monitoring and adjustments, and leverage the latest large language models. In the future, the system will be further optimized to help control emerging and major infectious diseases more effectively.</div></div>","PeriodicalId":33615,"journal":{"name":"Global Transitions","volume":"6 ","pages":"Pages 249-255"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142650926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Factors related to preventive measures towards PM2.5 exposure: A systematic review","authors":"Jeevan Bhatta, Orapin Laosee, Cheerawit Rattanapan","doi":"10.1016/j.glt.2024.10.002","DOIUrl":"10.1016/j.glt.2024.10.002","url":null,"abstract":"<div><div>Fine particulate matter (PM<sub>2.5</sub>) exposure is a growing public concern that needs effective preventive measures. Adopting preventive measures plays a vital role in determining one's actions. This study systematically analyzed the factors related to preventive measures towards PM<sub>2.5</sub> exposure. A comprehensive search was performed in PubMed, Scopus, and Embase. A total of ten relevant studies were included in the study. The systematic review demonstrated that personal attitude towards PM<sub>2.5</sub>, perceived behavioral control, perceived risk, and subjective norms consistently had the most substantial impact on the intention to adopt preventive measures. Moreover, negative emotions, social norms, and educational level were also significant factors supported by consistent evidence across studies. Furthermore, perceived severity, perceived susceptibility, perceived sensationalism, perceived norms, subjective norms, institutional trust, self-efficacy, income, desire, and knowledge also played a vital role in adopting preventive measures toward PM<sub>2.5</sub> exposure. The study accentuates numerous approaches to determine an individual's intention in mitigating the effects of PM<sub>2.5</sub> exposure. The interplay between these factors highlights the complexity of PM<sub>2.5</sub> preventive measures. However, the review identified research gaps, including limited longitudinal studies and a need for more focus on actual behavior change beyond intention. Further research should address these gaps to inform more effective interventions for PM<sub>2.5</sub> exposure mitigation at the personal level.</div></div>","PeriodicalId":33615,"journal":{"name":"Global Transitions","volume":"6 ","pages":"Pages 212-220"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142445930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cancer as a global health crisis with deep evolutionary roots","authors":"Rainer Johannes Klement","doi":"10.1016/j.glt.2024.01.001","DOIUrl":"https://doi.org/10.1016/j.glt.2024.01.001","url":null,"abstract":"<div><p>The global burden of cancer incidence, deaths and economic costs is steadily increasing since several decades. Despite a massive allocation of research funds since the 1970s, no significant (in terms of years) improvements of survival times have been achieved for most cancer types. In this article, I argue that the failure to effectively prevent and treat cancer is partly owing to the gene-centric paradigm of the somatic mutation theory of carcinogenesis. I outline and provide evidence for a new transdisciplinary evolutionary theory of carcinogenesis according to which cancer is a phylogenetic reversal towards unicellular lifeforms triggered by the breakdown of essential cooperative interactions on important levels of human organization. These levels include the genetic, cellular, tissue and psychosocial-spiritual level of human existence. The new theory considers the emergence of eukaryotes and metazoans and – of particular importance – human evolution and in this way explains why cooperation on these different levels is so essential to maintain holistic health. It is argued that the interaction between human’s slow natural evolution and the fast cultural evolution, especially during the current Anthropocene epoch, plays an important role in making individuals susceptible towards carcinogenesis. The implications of this insight and the theory of cancer as a phylogenetic reversal are discussed with respect to prevention and treatment, and concrete practical examples are provided. It is concluded that individuals could substantially reduce their risk of cancer by respecting certain biopsychosocial-spiritual lifestyle factors which are justified by human evolution.</p></div>","PeriodicalId":33615,"journal":{"name":"Global Transitions","volume":"6 ","pages":"Pages 45-65"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S258979182400001X/pdfft?md5=0b4430ed629ed9fef059ed00efc345ee&pid=1-s2.0-S258979182400001X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139434282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Advancing diabetic retinopathy diagnosis with fundus imaging: A comprehensive survey of computer-aided detection, grading and classification methods","authors":"S. Prathibha, Siddappaji","doi":"10.1016/j.glt.2024.04.001","DOIUrl":"https://doi.org/10.1016/j.glt.2024.04.001","url":null,"abstract":"<div><p>The incidence of diabetic retinopathy globally calls for advanced and more universally applicable computer-aided diagnosis (CAD) systems. This survey paper explores the current state of vision-based CAD techniques for the detection and classification of diabetic retinopathy, a diabetes-induced eye disorder that can lead to severe visual impairment or blindness. Characterized by a variety of manifestations including microaneurysms, exudates, hemorrhages, and macular detachment, diabetic retinopathy presents substantial challenges for automated detection. This is primarily due to the heterogeneity of retinal fundus images, which display diverse spatiotextural features and intricate vascular structures. Our exhaustive review indicates that most existing methodologies predominantly concentrate on isolated diabetic retinopathy types, employing localized spatiotextural feature analysis for classification. Such specificity often results in limited accuracy and generalizability, restricting practical real-world application. Furthermore, contemporary leading methods generally focus on single retinal characteristics, necessitating patients to undergo multiple CAD procedures, thereby increasing time, costs, and possibly intensifying retinal complexities. To overcome these obstacles, we propose the adoption of multi-trait-driven CAD solutions. Utilizing the potent capabilities of deep learning, these solutions could employ high-dimensional, multi-cue sensitive feature extraction and ensemble learning for classification. This approach is designed to improve the generalizability and dependability of CAD systems, offering a holistic solution capable of effectively managing the diverse manifestations of diabetic retinopathy. Our study highlights the need for a fundamental transformation in diabetic retinopathy CAD systems, motivating further research towards robust, multi-modal methods to enhance detection, classification, and grading of this widespread ailment.</p></div>","PeriodicalId":33615,"journal":{"name":"Global Transitions","volume":"6 ","pages":"Pages 93-112"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2589791824000045/pdfft?md5=135655ab9ce675119e976cfded0d8e40&pid=1-s2.0-S2589791824000045-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140900998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xuemin Zhu , Yuehua Liu , Wei Dai , Wannian Liang , Guanqiao Li
{"title":"Reduction in inpatient and severe condition visits for respiratory diseases during the COVID-19 pandemic in Wuhan, China","authors":"Xuemin Zhu , Yuehua Liu , Wei Dai , Wannian Liang , Guanqiao Li","doi":"10.1016/j.glt.2023.12.001","DOIUrl":"https://doi.org/10.1016/j.glt.2023.12.001","url":null,"abstract":"<div><h3>Background</h3><p>In Wuhan, China, a stringent lockdown was implemented to contain the spread of COVID-19, transitioning later to normalised prevention and control strategy. This study examines the trends in hospital visits for acute and chronic respiratory diseases, with a focus on outpatient, inpatient, and severe condition visits.</p></div><div><h3>Methods</h3><p>The study used administrative health insurance data spanning from January 2018 to August 2021, an interrupted time series analysis was conducted to assess the trend in hospital visits per million population for respiratory diseases. To confirm whether the change was exclusive to respiratory diseases, neoplasms and intracerebral haemorrhage were used as controls. The impact of the pandemic was estimated by comparing by weekly admissions to pre-pandemic levels. Subgroup analyses dissected variations by disease and visit types.</p></div><div><h3>Results</h3><p>Hospital visits for respiratory diseases declined significantly during the lockdown and exhibited a slower recovery in the later normalised prevention and control period compared to the control conditions. As of August 2021, outpatient visits increased by over 22.2% above the pre-pandemic level, while inpatient and severe condition visits witnessed significant reductions, falling to 46.7% and 80.6% of pre-pandemic levels, respectively. Compared to three other subgroups, visits for acute lower respiratory infections experienced the most significant decline, with inpatient and severe visits dropping to 23.9% and 25.7% of pre-pandemic levels.</p></div><div><h3>Interpretation</h3><p>Our study revealed a persistent reduction in inpatient and severe case visits for respiratory diseases throughout the ongoing pandemic. These findings suggested the possible role of non-pharmaceutical interventions in mitigating acute and chronic non-COVID respiratory diseases.</p></div>","PeriodicalId":33615,"journal":{"name":"Global Transitions","volume":"6 ","pages":"Pages 37-44"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2589791823000385/pdfft?md5=9ac30ea9d45cf0d305566a2df4793ea9&pid=1-s2.0-S2589791823000385-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139399450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Wei Zheng , Xin Yan , Shengnan Liang , Kaiwen Ma , Xianxian Yuan , Lirui Zhang , Junhua Huang , Ruihua Yang , Huiyuan Pang , Li Zhang , Zhihong Tian , Guanghui Li
{"title":"The reduction in macrosomia prevalence over a decade following the intensive intervention programs","authors":"Wei Zheng , Xin Yan , Shengnan Liang , Kaiwen Ma , Xianxian Yuan , Lirui Zhang , Junhua Huang , Ruihua Yang , Huiyuan Pang , Li Zhang , Zhihong Tian , Guanghui Li","doi":"10.1016/j.glt.2024.08.001","DOIUrl":"10.1016/j.glt.2024.08.001","url":null,"abstract":"<div><h3>Objective</h3><p>To assess changes in macrosomia prevalence following a two-stage lifestyle intervention program.</p></div><div><h3>Methods</h3><p>The study collected annual delivery data from singleton pregnant women at the Beijing Obstetrics and Gynecology Hospital in Beijing, China (2014–2023). The first intervention stage involved nutritional assessment and lifestyle management in pregnancy, and maternal weight and fetal growth monitoring were added in the second stage, with intensive management as necessary. Pre-intervention births (2014–2016) served as controls. The change in macrosomia and low birth weight prevalence following the intervention was assessed by an interrupted time series analysis.</p></div><div><h3>Results</h3><p>Among 126,824 pregnant women, macrosomia prevalence decreased from 7.11 % to 4.15 % over ten years, with an accelerated decrease post-intervention (p for slope = 0.050 and 0.004 for the first and second stages), primarily contributed by the reduction in excessive gestational weight gain (adjusted population attributable risk = 28.6 %, p for Granger cause = 0.0001). The change in the increasing rate of low-birth-weight prevalence was non-significant.</p></div><div><h3>Conclusions</h3><p>Macrosomia prevalence significantly decreased over a decade following the intensive intervention programs.</p></div>","PeriodicalId":33615,"journal":{"name":"Global Transitions","volume":"6 ","pages":"Pages 187-193"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2589791824000124/pdfft?md5=40b2f062e34ff9994490b8b295daad38&pid=1-s2.0-S2589791824000124-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142172044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fulin Wang , Wanzhou Wang , Feifei Zhang , Chao Yang , Pengfei Li , Jinwei Wang , Shaoqing Wei , Shaowei Wu , Luxia Zhang
{"title":"Non-optimum temperatures modified the associations between PM2.5 and its components and hospitalizations for chronic kidney disease in China","authors":"Fulin Wang , Wanzhou Wang , Feifei Zhang , Chao Yang , Pengfei Li , Jinwei Wang , Shaoqing Wei , Shaowei Wu , Luxia Zhang","doi":"10.1016/j.glt.2024.09.001","DOIUrl":"10.1016/j.glt.2024.09.001","url":null,"abstract":"<div><div>Epidemiological evidence concerning whether exposure to fine particulate matter (PM<sub>2.5</sub>) and its components was linked to an elevated risk of hospitalizations for chronic kidney disease (CKD) remains insufficient. Moreover, it remains unclear whether ambient temperatures have potential modification effects on PM<sub>2.5</sub>'s impacts. In the current study, we collected a nationwide sample of 2,259,240 hospitalization records for CKD in 260 Chinese cities. The associations between air pollutants and CKD hospitalizations were determined by the space-time-stratified case-crossover design. We further assessed the effects of PM<sub>2.5</sub> and its components in three temperature strata [i.e., lowest (<25th), medium (25–75th), and highest (>75th)]. The findings demonstrated the significant and monotonic associations between risk of CKD hospitalizations and exposure to PM<sub>2.5</sub>, black carbon (BC), sulfate (SO<sub>4</sub><sup>2−</sup>), nitrate (NO<sub>3</sub><sup>−</sup>), ammonium (NH<sub>4</sub><sup>+</sup>), and organic matter (OM). For instance, along with an interquartile range increment in PM<sub>2.5</sub> (29.47 μg/m<sup>3</sup>), the relative risks (RR) were 1.016 (95 % confidence interval [CI]:1.012–1.019) at lag 0–4 days. Higher ambient temperature significantly exacerbated the estimated impact of PM<sub>2.5</sub> and its components on CKD hospitalizations, while significantly stronger associations were also observed at lower temperature for SO<sub>4</sub><sup>2−</sup> and NO<sub>3</sub><sup>−</sup>. The modification effects of non-optimum temperatures varied among different etiologies of CKD and geographic regions. This study provides insights into the joint kidney health effects of climate change and air pollution. These findings highlight the necessity of protection measures against high concentration of PM<sub>2.5</sub> and non-optimum temperatures for the vulnerable populations.</div></div>","PeriodicalId":33615,"journal":{"name":"Global Transitions","volume":"6 ","pages":"Pages 194-202"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2589791824000136/pdfft?md5=39c7612de8f48d6d7b1c6c30a20c4d1e&pid=1-s2.0-S2589791824000136-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142315427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}