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The roles of psychological resilience and burnout on the association between physical exercise and perceived competency among radiology residents in China: results from a national survey 心理弹性和倦怠在中国放射科住院医师体育锻炼与感知能力关系中的作用:一项全国性调查结果
IF 4.2
Global Transitions Pub Date : 2026-10-01 Epub Date: 2026-09-17 DOI: 10.1016/j.glt.2026.09.003
Yuhang Zhang, Peicheng Wang, Hange Li, Maoqing Jiang, Jingfeng Zhang, Jianjun Zheng, Zhenchang Wang, Zhenghan Yang, Jiming Zhu, Sitong Luo
{"title":"The roles of psychological resilience and burnout on the association between physical exercise and perceived competency among radiology residents in China: results from a national survey","authors":"Yuhang Zhang,&nbsp;Peicheng Wang,&nbsp;Hange Li,&nbsp;Maoqing Jiang,&nbsp;Jingfeng Zhang,&nbsp;Jianjun Zheng,&nbsp;Zhenchang Wang,&nbsp;Zhenghan Yang,&nbsp;Jiming Zhu,&nbsp;Sitong Luo","doi":"10.1016/j.glt.2026.09.003","DOIUrl":"10.1016/j.glt.2026.09.003","url":null,"abstract":"<div><h3>Objective</h3><div>Radiology residents are essential healthcare personnel resources in clinical settings. This study aimed to test the mediating role of psychological resilience and burnout in the association between physical exercise frequency and perceived competency among radiology residents in China.</div></div><div><h3>Methods</h3><div>In this online cross-sectional survey, data were collected from December 1, 2020 to April 30, 2021. All the radiology residents from 31 provinces in China were targeted. Path analysis was performed to estimate the mediation effect of resilience and burnout on the association between physical exercise frequency and perceived competency. Statistical analyses were performed using SPSS 28.0 and Mplus 7.4 software.</div></div><div><h3>Results</h3><div>The overall response rate of this survey was 30% (3666/12,208). Among the 3666 effectively responding radiology residents, the mean age was 27.3 years (SD = 2.6) and 42.0% were males. 78.9% of them engaged in physical exercise less than twice per month. The mean score of the perceived competency was 28.1 (SD = 13.1). The path analysis showed that radiology residents with a higher frequency of physical exercise reported more resilience and less burnout, which were in turn associated with a higher level of perceived competency (<em>p</em> &lt; 0.001).</div></div><div><h3>Conclusions</h3><div>The large-scale study revealed that physical exercise was associated with higher perceived competency among radiology residents in China, and that this association may be mediated by greater resilience and lower levels of burnout. Interventions aimed at enhancing the perceived competency of resident physicians should focus on promoting their health lifestyles and psychological well-being.</div></div>","PeriodicalId":33615,"journal":{"name":"Global Transitions","volume":"8 2","pages":"Pages 377-384"},"PeriodicalIF":4.2,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149153791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bulk corrigenda regarding duplicated references in previously published articles in Volume 6 – Volume 8 关于第6卷-第8卷以前发表的文章中重复引用的大量更正
IF 4.2
Global Transitions Pub Date : 2026-10-01 Epub Date: 2026-09-28 DOI: 10.1016/j.glt.2026.09.004
{"title":"Bulk corrigenda regarding duplicated references in previously published articles in Volume 6 – Volume 8","authors":"","doi":"10.1016/j.glt.2026.09.004","DOIUrl":"10.1016/j.glt.2026.09.004","url":null,"abstract":"","PeriodicalId":33615,"journal":{"name":"Global Transitions","volume":"8 2","pages":"Pages 385-389"},"PeriodicalIF":4.2,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149153792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Causal effects of unintended pregnancy on adverse birth outcomes: A target trial emulation analysis 意外妊娠对不良分娩结局的因果影响:一项目标试验模拟分析
IF 4.2
Global Transitions Pub Date : 2026-10-01 Epub Date: 2026-09-18 DOI: 10.1016/j.glt.2026.09.005
Mengyang Zhang, Jie Ni, Shangqiu Zou, Xinyi Rong, Kaipu Wu, Xin Qin, Zhiyao Li, Qiong Wang
{"title":"Causal effects of unintended pregnancy on adverse birth outcomes: A target trial emulation analysis","authors":"Mengyang Zhang,&nbsp;Jie Ni,&nbsp;Shangqiu Zou,&nbsp;Xinyi Rong,&nbsp;Kaipu Wu,&nbsp;Xin Qin,&nbsp;Zhiyao Li,&nbsp;Qiong Wang","doi":"10.1016/j.glt.2026.09.005","DOIUrl":"10.1016/j.glt.2026.09.005","url":null,"abstract":"<div><h3>Background</h3><div>Unintended pregnancy is a global public health concern, yet its causal effects on adverse birth outcomes remain unclear. This study applied target trial emulation (TTE) to estimate its causal effects on low birth weight (LBW) and preterm birth (PTB).</div></div><div><h3>Methods</h3><div>We analyzed Demographic and Health Surveys (DHS) data across 37 low- and middle-income countries (LMICs) from 1997 to 2021. Under the TTE framework, eligible pregnancies were assigned to intended or unintended groups. Inverse probability of treatment and censoring weighting were applied to address confounding and loss to follow-up (LTFU), respectively. A generalized linear mixed model (GLMM) was used to estimate risk ratios (RRs). For comparison, a conventional covariate-adjusted Poisson regression was conducted. Stratified and sensitivity analyses were performed to assess robustness. The E-value was estimated to evaluate the potential impact of unmeasured confounding.</div></div><div><h3>Results</h3><div>Among 911,423 pregnancies from 635,139 women, 205,655 were unintended. In the TTE analysis, unintended pregnancy was significantly associated with an increased risk of PTB (RR = 1.267, 95% CI: 1.167-1.376), but not LBW (RR = 0.972, 95% CI: 0.914-1.035). In contrast, Poisson regression showed significant associations with both outcomes (LBW: RR = 1.090, 95% CI: 1.067-1.114; PTB: RR = 1.110, 95% CI: 1.084-1.137). Stratified and sensitivity analyses generally supported the primary findings. The E-value for PTB was 1.849.</div></div><div><h3>Conclusion</h3><div>Unintended pregnancy may causally increase PTB risk, but is not associated with LBW. The findings support strengthening maternal healthcare, reproductive health education, and contraceptive access in LMICs.</div></div>","PeriodicalId":33615,"journal":{"name":"Global Transitions","volume":"8 2","pages":"Pages 390-400"},"PeriodicalIF":4.2,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149153794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of sociodemographic development on the global burden of urological cancers attributable to modifiable risk factors, 1990–2021: A population-based study 1990-2021年社会人口发展对可改变风险因素导致的全球泌尿系统癌症负担的影响:一项基于人群的研究
IF 3.1
Global Transitions Pub Date : 2026-05-01 Epub Date: 2026-02-03 DOI: 10.1016/j.glt.2026.02.001
Xiaoyue Shi , Wei Cao , Chenran Wang , Yadi Zheng , Jiaxin Xie , Zilin Luo , Xiaolu Chen , Zeming Guo , Fei Wang , Xuesi Dong , Ni Li
{"title":"Impact of sociodemographic development on the global burden of urological cancers attributable to modifiable risk factors, 1990–2021: A population-based study","authors":"Xiaoyue Shi ,&nbsp;Wei Cao ,&nbsp;Chenran Wang ,&nbsp;Yadi Zheng ,&nbsp;Jiaxin Xie ,&nbsp;Zilin Luo ,&nbsp;Xiaolu Chen ,&nbsp;Zeming Guo ,&nbsp;Fei Wang ,&nbsp;Xuesi Dong ,&nbsp;Ni Li","doi":"10.1016/j.glt.2026.02.001","DOIUrl":"10.1016/j.glt.2026.02.001","url":null,"abstract":"<div><h3>Objectives</h3><div>The burden of urological cancers attributable to modifiable risk factors varies across sociodemographic contexts, yet a comprehensive assessment of the impact of development levels remains lacking.</div></div><div><h3>Methods</h3><div>Using data from the Global Burden of Disease 2021 study, we assessed associations between the Sociodemographic Index (SDI) and age-standardized mortality rates (ASMRs) of urological cancers attributable to modifiable risk factors across 204 countries in 2021. Trends in ASMRs and disability-adjusted life year (DALY) rates from 1990 to 2021 were analyzed using estimated annual percentage change (EAPC). Mortality changes were decomposed into four components. Inequalities were quantified using the slope index of inequality (SII) and concentration index (CI).</div></div><div><h3>Results</h3><div>SDI was positively correlated with ASMRs for all five attributable burdens. Countries with higher SDI exhibited the highest ASMR and DALY rates. Notably, in low-middle SDI countries, bladder cancer due to high FPG and kidney cancer due to high BMI showed the steepest increases. These countries also experienced slower declines or even upward trends in smoking-attributable mortality. Decomposition revealed varying contributions of risk-deleted rates and aging. Most SDI-related inequalities widened or remained stable.</div></div><div><h3>Conclusion</h3><div>Sociodemographic development critically shapes the burden of urological cancers attributable to modifiable risks, highlighting the need for development-tailored preventive strategies.</div></div>","PeriodicalId":33615,"journal":{"name":"Global Transitions","volume":"8 1","pages":"Pages 231-238"},"PeriodicalIF":3.1,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146187558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The relationship between cities' digitalization degrees and residents' health behaviors: An empirical study of 289 cities in China 城市数字化程度与居民健康行为的关系——基于中国289个城市的实证研究
IF 3.1
Global Transitions Pub Date : 2026-05-01 Epub Date: 2026-01-27 DOI: 10.1016/j.glt.2026.01.004
Tianran Wang , Jinyu He , Yiran Wang , Wenwen Liu , Xueyao Zhang , Ning Zhang , Wannian Liang
{"title":"The relationship between cities' digitalization degrees and residents' health behaviors: An empirical study of 289 cities in China","authors":"Tianran Wang ,&nbsp;Jinyu He ,&nbsp;Yiran Wang ,&nbsp;Wenwen Liu ,&nbsp;Xueyao Zhang ,&nbsp;Ning Zhang ,&nbsp;Wannian Liang","doi":"10.1016/j.glt.2026.01.004","DOIUrl":"10.1016/j.glt.2026.01.004","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Background&lt;/h3&gt;&lt;div&gt;Residents' health behaviors are crucial factors in the prevention of diseases. A city's digitalization degree refers to the extent to which digital infrastructure and products can empower local industries and residents. Existing studies about the influence of digital technologies and products on health behaviors are mainly individual-level studies. Extant city-level studies primarily investigate the influence of cities' digitalization degrees on economic and environmental factors. There is a lack of city-level study examining the impact of cities' digitalization degrees on residents' health behaviors.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Method&lt;/h3&gt;&lt;div&gt;This study constructs a panel dataset comprising the data of 289 prefecture-level or above cities in China in the period from 2020 to 2023. Regression models are employed to examine the relationship between cities' digitalization degrees and residents’ health behaviors. Based on geographic locations, cities are sorted as “eastern or middle cities” and “western cities”. According to the concentration level of economic and social resources, cities are sorted into “central cities” and “non-central cities”. Based on these two categorizations, the heterogeneity of the main effect is also investigated. Furthermore, the average slopes and the dummy variable indicating whether a city is selected by the “Broadband China Strategy” are utilized as instrumental variables to address the endogeneity caused by omitted variables.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;div&gt;In the basic regression model, cities' digitalization degrees show significantly positive relationship with residents' health behaviors (β&lt;sub&gt;1&lt;/sub&gt; = 0.178, 95 % CI [0.042, 0.315], p = 0.011; β&lt;sub&gt;2&lt;/sub&gt; = 0.841, 95 % CI [0.458, 1.225], p &lt; 0.001). The result is robust in the regression models using instrumental variables. Heterogeneity analysis indicates that for “eastern and middle cities”, there is a significantly positive relationship between cities' digitalization degrees and residents' health behaviors (β&lt;sub&gt;1&lt;/sub&gt; = 0.251, 95 % CI [0.105, 0.396], p = 0.001; β&lt;sub&gt;2&lt;/sub&gt; = 0.986, 95 % CI [0.512, 1.459], p &lt; 0.001), while this relationship is not significant for “western cities” (β&lt;sub&gt;1&lt;/sub&gt; = 0.032, 95 % CI [-0.176, 0.242], p = 0.759; β&lt;sub&gt;2&lt;/sub&gt; = 0.500, 95 % CI [-0.138, 1.139], p = 0.123). For “non-central cities”, there is a significantly positive relationship between cities' digitalization degrees and residents’ health behaviors (β&lt;sub&gt;1&lt;/sub&gt; = 0.285, 95 % CI [0.107, 0.463], p = 0.002; β&lt;sub&gt;2&lt;/sub&gt; = 1.097, 95 % CI [0.670, 1.524], p &lt; 0.001), while this relationship is not significant for “central cities” (β&lt;sub&gt;1&lt;/sub&gt; = 0.014, 95 % CI [-0.184, 0.213], p = 0.885; β&lt;sub&gt;2&lt;/sub&gt; = 0.146, 95 % CI [-0.593, 0.886], p = 0.690).&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Interpretation&lt;/h3&gt;&lt;div&gt;Digitalization of cities can promote residents' health behaviors for three potential reasons. First, cities' digitalization degrees improve loc","PeriodicalId":33615,"journal":{"name":"Global Transitions","volume":"8 1","pages":"Pages 223-230"},"PeriodicalIF":3.1,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146187479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
When ethical duties to ensure patient health and to minimise environmental impacts conflict in hospital design: Lessons from an Australian case study 在医院设计中,当确保病人健康和尽量减少环境影响的道德责任发生冲突时:来自澳大利亚案例研究的经验教训
IF 3.1
Global Transitions Pub Date : 2026-05-01 Epub Date: 2025-12-19 DOI: 10.1016/j.glt.2025.12.002
Bridget Pratt , David G. Kirchhoffer
{"title":"When ethical duties to ensure patient health and to minimise environmental impacts conflict in hospital design: Lessons from an Australian case study","authors":"Bridget Pratt ,&nbsp;David G. Kirchhoffer","doi":"10.1016/j.glt.2025.12.002","DOIUrl":"10.1016/j.glt.2025.12.002","url":null,"abstract":"<div><div>Healthcare systems have an ethical duty to ensure equal access to high-quality healthcare as a matter of social justice. In their pursuit of that duty, they generate substantial environmental harms. For that reason, healthcare systems <em>also</em> have an ethical duty to minimise their environmental impacts as a matter of environmental justice and ecological justice. Many countries are already transitioning to less environmentally harmful healthcare. This study investigates whether the two duties come into tension when designing new green hospitals and how such tensions (if found to eventuate) are navigated in practice. We conducted case study research in collaboration with an Australian hospital network, with one of the network's new public hospital builds comprising our case of focus. We undertook semi-structured interviews between March and June 2023 with those responsible for making design decisions in relation to the new public hospital being built. We analysed interview data thematically and report three main themes: separating the clinical and the environmental; tensions; and addressing tensions. We conclude by providing analysis of what is at stake in identified tensions using theories of justice, offering lessons that can help other hospitals mitigate against such tensions arising, and considering whether and when the moral reasoning employed in the case-under-study should be used to navigate the tensions. This study provides those responsible for green hospital design with a better understanding of what tensions they are likely to encounter between health, social, and environmental goods and how to reduce those tensions' occurrence. That understanding will help them to identify and avoid such tensions in their practice, but further work is needed to develop ethical guidance on how they should navigate the tensions when they occur.</div></div>","PeriodicalId":33615,"journal":{"name":"Global Transitions","volume":"8 1","pages":"Pages 181-192"},"PeriodicalIF":3.1,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146187480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Performance of the large language model in general medicine 大语言模型在全科医学中的表现
IF 3.1
Global Transitions Pub Date : 2026-05-01 Epub Date: 2025-10-28 DOI: 10.1016/j.glt.2025.10.004
Liyuan Tao , Jue Liu , Xiaoqin Lu , Yali Zhao , Yifan Zhang , Zuyi Zhu , Ting Li , Zhishou Zhang , Yipin Zhang , Wenxin Yan , Min Liu , Wannian Liang
{"title":"Performance of the large language model in general medicine","authors":"Liyuan Tao ,&nbsp;Jue Liu ,&nbsp;Xiaoqin Lu ,&nbsp;Yali Zhao ,&nbsp;Yifan Zhang ,&nbsp;Zuyi Zhu ,&nbsp;Ting Li ,&nbsp;Zhishou Zhang ,&nbsp;Yipin Zhang ,&nbsp;Wenxin Yan ,&nbsp;Min Liu ,&nbsp;Wannian Liang","doi":"10.1016/j.glt.2025.10.004","DOIUrl":"10.1016/j.glt.2025.10.004","url":null,"abstract":"<div><h3>Background</h3><div>Domain-specific large language models (LLMs) may aid primary care, but reliability and safety are uncertain, and general-practice evaluations remain limited.</div></div><div><h3>Methods</h3><div>Observational, exam-based comparison (Feb–May 2025) using standardized items from the Chinese General Practitioner Licensing Examination. A general-practice LLM (AIGP) was evaluated against 389 physicians on the same items under deterministic decoding. Each item was run 50 technical replicates. Outcomes: accuracy; stability (coefficient of variation, ICC(2,k)); and expert-rated potential clinical harm for incorrect outputs.</div></div><div><h3>Results</h3><div>AIGP achieved 88.41 % ± 1.87 accuracy vs physicians 72.12 % ± 4.97 (mean difference 16.29, 95 % CI 15.56–17.01; P &lt; .001). Stability favored AIGP (CV 2.12 vs 6.89; agreement across replicates ICC(2,k) = 0.993, 95 % CI 0.991–0.995). Although overall errors were fewer, AIGP's mistakes were systematic and carried higher average harm ratings, clustering in red-flag contexts (pregnancy, pediatrics, anticoagulation, acute chest pain).</div></div><div><h3>Conclusions</h3><div>In a controlled test setting, AIGP outperformed physicians and showed excellent stability. Findings are exploratory and context-limited (exam-based, text-only) and reveal systematic higher-harm failure modes. AIGP is a starting point for decision support, not a deployable clinical tool without prospective real-world validation and safety guardrails (human-in-the-loop review, contraindication/dose checks, uncertainty-aware refusal).</div></div>","PeriodicalId":33615,"journal":{"name":"Global Transitions","volume":"8 1","pages":"Pages 101-109"},"PeriodicalIF":3.1,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145690784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Leveraging AI innovation for a sustainable environment in G-7: Finance and governance roles 在七国集团中利用人工智能创新实现可持续环境:财务和治理角色
IF 3.1
Global Transitions Pub Date : 2026-05-01 Epub Date: 2026-01-07 DOI: 10.1016/j.glt.2026.01.001
Mohammad Ridwan , Md. Rajabul Hassan , Amit Debnath , Afsana Akther , Khurshid Khudoykulov , Md. Emran Hossain , Miguel Angel Esquivias
{"title":"Leveraging AI innovation for a sustainable environment in G-7: Finance and governance roles","authors":"Mohammad Ridwan ,&nbsp;Md. Rajabul Hassan ,&nbsp;Amit Debnath ,&nbsp;Afsana Akther ,&nbsp;Khurshid Khudoykulov ,&nbsp;Md. Emran Hossain ,&nbsp;Miguel Angel Esquivias","doi":"10.1016/j.glt.2026.01.001","DOIUrl":"10.1016/j.glt.2026.01.001","url":null,"abstract":"<div><div>Rising ecological footprints in G-7 countries pose significant challenges to global sustainability, despite their economic and technological leadership. While prior research has examined individual drivers of environmental degradation in advanced economies, there remains a critical gap in understanding the integrated roles of artificial intelligence (AI), financial accessibility, and government effectiveness in mitigating ecological pressures, particularly through comprehensive panel data analysis in the G-7 context. This study addresses this gap by exploring how these factors influence environmental sustainability across G-7 nations, using the ecological footprint as a key indicator from 2010Q1 to 2022Q4. Employing the Panel Mean Group Autoregressive Distributed Lag model as the primary estimator, with Augmented Mean Group and Common Correlated Effects Mean Group estimators for robustness, the empirical results reveal that economic growth and urbanization significantly exacerbate ecological degradation in both the long and short run. Conversely, AI innovation, financial accessibility, and effective governance substantially reduce environmental impacts. These findings advance the discourse on Sustainable Development Goals (SDGs), especially SDG 9 (Industry, Innovation and Infrastructure), SDG 11 (Sustainable Cities and Communities), and SDG 13 (Climate Action). To foster a sustainable transition, policymakers should prioritize investments in AI-driven green technologies to optimize resource efficiency, expand inclusive financial mechanisms to fund eco-innovations and renewable projects, and implement governance reforms that enforce stringent environmental regulations in G-7 economies.</div></div>","PeriodicalId":33615,"journal":{"name":"Global Transitions","volume":"8 1","pages":"Pages 166-180"},"PeriodicalIF":3.1,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145975961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Racial disparities in the association of epigenetic age acceleration with the transition between normal cognition, mild cognitive impairment and dementia 种族差异在表观遗传年龄加速与正常认知、轻度认知障碍和痴呆之间的过渡之间的关系
IF 3.1
Global Transitions Pub Date : 2026-05-01 Epub Date: 2025-08-07 DOI: 10.1016/j.glt.2025.08.001
Guangwen Liu , Chenlu Hong , Yujie Huang , Boyuan Guan , Yating Liu , Zhaorui Liu , Yanan Luo
{"title":"Racial disparities in the association of epigenetic age acceleration with the transition between normal cognition, mild cognitive impairment and dementia","authors":"Guangwen Liu ,&nbsp;Chenlu Hong ,&nbsp;Yujie Huang ,&nbsp;Boyuan Guan ,&nbsp;Yating Liu ,&nbsp;Zhaorui Liu ,&nbsp;Yanan Luo","doi":"10.1016/j.glt.2025.08.001","DOIUrl":"10.1016/j.glt.2025.08.001","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Background&lt;/h3&gt;&lt;div&gt;This study aimed to explore the association between epigenetic age acceleration and the transition between different cognitive status during dementia process. We also verified the racial disparities in the above relationships.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Methods&lt;/h3&gt;&lt;div&gt;Data was from the US Health and Retirement Study, involving 3593 participants (50+) with a 4-year follow-up. Normal cognition (NC), mild cognitive impairment (MCI) and dementia was evaluated by the modified Telephone Interview for Cognitive Status. Epigenetic age was determined by epigenetic clocks based on DNA methylation patterns and dichotomized into acceleration and deceleration according to residual from the regression of epigenetic age on chronological age. Cox regression models were conducted to examine the association between epigenetic age acceleration and risk of transition between NC, MCI and dementia. Subgroup analysis was conducted to verify racial disparities.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;div&gt;Among those with NC at baseline (n = 2671), 1053 (39.42 %) were male, 1618 (60.58 %) were female, 2057 (77.01 %) were Whites, and 614 (22.99 %) were Non-Whites. A total of 278 participants developed the transition from NC to MCI and 42 participants developed the transition from NC to dementia during the median follow-up of 3.92 years (interquartile range: 1.17–4.83 years). Accelerated epigenetic aging measured by GrimAge clock was associated with higher risk of MCI incidence (HR = 1.56, 95 % CI: 1.15–2.11) whereas epigenetic age acceleration measured by all the seven epigenetic clocks and the risk of transition from NC to dementia was not associated. Among those with MCI at baseline (n = 922), 408 (44.25 %) were male, 514 (55.75 %) were female, 633 (68.66 %) were Whites, and 289 (31.34 %) were Non-Whites. A total of 132 participants experienced transition from MCI to dementia during the median follow-up of 3.58 years (interquartile range: 1.17–4.67 years). Participants with age acceleration measured by Horvath's skin&amp;blood clock had a higher risk of transition from MCI to dementia (HR = 1.62, 95 % CI: 1.09–2.40). Heterogeneity of race was found in the relationship of epigenetic aging with transition between cognitive status and the observed associations only existed among non-Whites. Specifically, associations between GrimAge AccelAge and higher risk of transition from NC to MCI (HR = 2.04, 95 % CI: 1.10–3.79, &lt;em&gt;P&lt;/em&gt; for interaction = 0.039) as well as transition from NC to dementia (HR = 3.71, 95 % CI: 1.03–13.34, &lt;em&gt;P&lt;/em&gt; for interaction = 0.040) were only found among Non-White participants. In addition, significant association between epigenetic age acceleration measured by Hannum (HR = 2.16, 95 % CI: 1.10–4.24, &lt;em&gt;P&lt;/em&gt; for interaction = 0.048), Horvath's skin&amp;blood (HR = 4.33, 95 % CI: 2.04–9.20, &lt;em&gt;P&lt;/em&gt; for interaction = 0.046), and Zhang's clock (HR = 1.94, 95 % CI: 1.07–3.51, &lt;em&gt;P&lt;/em&gt; for interaction = 0.046), and the higher","PeriodicalId":33615,"journal":{"name":"Global Transitions","volume":"8 1","pages":"Pages 1-9"},"PeriodicalIF":3.1,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144902428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Understanding the impact of digitalization transition of Senegal and its implication on human health and wellbeing 了解塞内加尔数字化转型的影响及其对人类健康和福祉的影响
IF 3.1
Global Transitions Pub Date : 2026-05-01 Epub Date: 2025-09-03 DOI: 10.1016/j.glt.2025.09.002
Madior Ndiaye, Raafat George Saade, Hao Liu
{"title":"Understanding the impact of digitalization transition of Senegal and its implication on human health and wellbeing","authors":"Madior Ndiaye,&nbsp;Raafat George Saade,&nbsp;Hao Liu","doi":"10.1016/j.glt.2025.09.002","DOIUrl":"10.1016/j.glt.2025.09.002","url":null,"abstract":"<div><div>Digitalization has become ubiquitous; however, stakeholders have varying degrees of integration globally. Within the context of this study, a digitalization strategy has the potential for economic growth, enhanced health services, and ensuring national stability, thereby improving social well-being and facilitating a country's emergence as a developing nation. This study seeks to examine Senegal's digital landscape, with a particular focus on its impact on health and well-being, which are pivotal in the nation's progression towards becoming an emerging country. This study identifies key themes and factors contributing to Senegal's digital transformation and its potential to enhance overall quality of life. A systematic literature review (SLR) revealed a paucity of relevant research specific to the Senegalese context. Through thematic analysis, we identified research gaps (themes) that could assist Senegal in achieving its digitalization objectives: incremental transitioning facilitated by broadband improvements; digitalization of the economic, political, and human resources sectors; influence of trust and perceived risk on the adoption of emerging technologies; and integration of emerging technologies across all facets of life. Moreover, we conducted a pilot survey based on the Unified Theory of Acceptance and Use of Technology to obtain additional insights into digital healthcare adoption.</div></div>","PeriodicalId":33615,"journal":{"name":"Global Transitions","volume":"8 1","pages":"Pages 37-55"},"PeriodicalIF":3.1,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145220721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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