Volume 3: Biomedical and Biotechnology Engineering最新文献_第3页

Human Pelvis Bayesian Injury Probability Curves From Whole Body Lateral Impact 人体骨盆侧向碰撞贝叶斯损伤概率曲线

Volume 3: Biomedical and Biotechnology Engineering Pub Date : 2019-11-11 DOI: 10.1115/imece2019-11860

N. Yoganandan, N. Devogel, F. Pintar, A. Banerjee

{"title":"Human Pelvis Bayesian Injury Probability Curves From Whole Body Lateral Impact","authors":"N. Yoganandan, N. Devogel, F. Pintar, A. Banerjee","doi":"10.1115/imece2019-11860","DOIUrl":"https://doi.org/10.1115/imece2019-11860","url":null,"abstract":"\u0000 Injury criteria are used in military, automotive, and aviation environments to advance human safety. While Injury Risk Curves (IRCs) for the human pelvis are published under vertical loading, there is a paucity of analysis that describe IRCs under lateral impact. The objective of the present study is to derive IRCs under this mode. Published data were used from 60 whole-body Post Mortem Human Surrogate (PMHS) tests that used repeated testing protocols. In the first analysis, from single impact tests, all injury data points were considered as left censored and noninjury points were considered as right censored, while repeated testing results were treated as interval censored data. In the second analysis, injury data were treated uncensored. Peak force was used as the response variable. Age, total body mass, gender, and Body Mass Index (BMI) were used as covariates in different combinations. Bayesian survival analysis model was used to derive the IRCs. Plus-minus 95% credible intervals (CI) and their Normalized CI Sizes (NCIS) were obtained. This is the first study to develop IRCs in whole body PMHS tests to describe the human pelvic tolerance under lateral impact using Bayesian models.","PeriodicalId":332737,"journal":{"name":"Volume 3: Biomedical and Biotechnology Engineering","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129172901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Motion Synthesis for Upper-Limb Rehabilitation Motion With Clustering-Based Machine Learning Method 基于聚类的机器学习方法的上肢康复运动综合

Volume 3: Biomedical and Biotechnology Engineering Pub Date : 2019-11-11 DOI: 10.1115/imece2019-10435

Chen Wenxiu, Song Wanbing, Haodong Chen, Qi Li, Ping Zhao

{"title":"Motion Synthesis for Upper-Limb Rehabilitation Motion With Clustering-Based Machine Learning Method","authors":"Chen Wenxiu, Song Wanbing, Haodong Chen, Qi Li, Ping Zhao","doi":"10.1115/imece2019-10435","DOIUrl":"https://doi.org/10.1115/imece2019-10435","url":null,"abstract":"\u0000 Nowadays, mechanical devices such as robots are widely adopted for limb rehabilitation. Due to the variety of human body parameters, the rehabilitation motion for different patient usually has its individual pattern. Thus it is obviously not an optimal solution to use a single motion generator to suit all patients. Yet it would also be unpractical if we design a different motion or even a different mechanism for each user individually. Therefore, in this paper we seek to adopt clustering-based machine learning technique to find a limited number of motion patterns for upper-limb rehabilitation, so that they could represent the large amount of those from people who have various body parameters. Firstly, the trajectory of a specified rehabilitation motion are recorded from various subjects, and then 4 types of machine learning algorithms (spectral clustering, hierarchical clustering, self-organizing mapping neural network and Gaussian mixture model) are implemented and compared. It is shown that spectral clustering (SC) yields the best performance and is hereby adopted to generate three clusters of motion patterns. After regression of each cluster, three types of motion for upper limb-rehabilitation are constructed, which could reflect the trajectories’ similarity and difference of people who have various body parameters. These work will provide help for the design of rehabilitation mechanisms.","PeriodicalId":332737,"journal":{"name":"Volume 3: Biomedical and Biotechnology Engineering","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132022426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Computational Analysis of Combat Helmet Protection Against Blunt Impact to Head 战斗头盔防头部钝器冲击的计算分析

Volume 3: Biomedical and Biotechnology Engineering Pub Date : 2019-11-11 DOI: 10.1115/imece2019-10903

X. Tan, A. Bagchi

{"title":"Computational Analysis of Combat Helmet Protection Against Blunt Impact to Head","authors":"X. Tan, A. Bagchi","doi":"10.1115/imece2019-10903","DOIUrl":"https://doi.org/10.1115/imece2019-10903","url":null,"abstract":"\u0000 Computational modeling provides significant benefits in assessing the helmet performance and identifying promising helmet designs. We develop multi-fidelity computational tools, representative virtual human head and helmet system models to help the design of next generation combat helmet with improved protection against blunt impact. By integrating the fast-running articulated human with personal protective equipment (PPE) biodynamics model with the high-fidelity human head with combat helmet finite element (FE) model, the multi-fidelity approach can be used to efficiently investigate impact-related traumatic brain injury (TBI) in the real-world scenario. The FE model is used to capture the dynamics of the composite helmet shell, foam pad suspension, retention strap and head while the biodynamics model provides the proper kinematics and boundary conditions for the FE model. An orthotropic elasto-plastic material with damage model is employed for the helmet shell. Enhanced tetrahedral elements are used to model the nearly-incompressible tissues. The head with helmet and without helmet under a severe impact due to a fall caused by blast loading are simulated and compared. The resulting biomechanical responses of head acceleration, shear stresses and strains in brain and mechanical injury criterion as well as helmet energy absorption are used to characterize the performance of helmet system.","PeriodicalId":332737,"journal":{"name":"Volume 3: Biomedical and Biotechnology Engineering","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134211758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Analysis of Ablation Volume Produced During Microwave Ablation of Breast Cancerous Lesion Using Fourier and Non-Fourier Models 用傅里叶和非傅里叶模型分析乳腺癌微波消融过程中产生的消融体积

Volume 3: Biomedical and Biotechnology Engineering Pub Date : 2019-11-11 DOI: 10.1115/imece2019-10800

Vellavalapalli Satish, Jatin Kumar, R. Repaka

{"title":"Analysis of Ablation Volume Produced During Microwave Ablation of Breast Cancerous Lesion Using Fourier and Non-Fourier Models","authors":"Vellavalapalli Satish, Jatin Kumar, R. Repaka","doi":"10.1115/imece2019-10800","DOIUrl":"https://doi.org/10.1115/imece2019-10800","url":null,"abstract":"\u0000 The present article aims to compare the change in the temperature and ablation volume during Microwave ablation procedure. The microwave ablation process is carried out using Fourier and non-Fourier bioheat transfer models in the computational domain of breast tumor. The above models have been considered with the relaxation time known as thermal delay during ablation procedure at constant power and frequency. The above objective has been carried out on a heterogeneous three compartment Breast model using COMSOL-Multiphysics software, with inbuilt bioheat transfer and electromagnetic waves Physics interfaces. The simulation results show that the ablation volume is slightly greater while using Fourier bioheat transfer model as compared to the non-Fourier bioheat transfer model. Further, the temperature distribution also shows that there is a slight variation initially at the start of the ablation, i.e., Fourier heat transfer model shows nearly 2°C more temperature as compared to the non Fourier model and becomes equal as the time increases. The present study helps in establishing the better clinical procedure of Microwave Ablation technique.","PeriodicalId":332737,"journal":{"name":"Volume 3: Biomedical and Biotechnology Engineering","volume":"47 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133973983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Laser Ablation Tomography for 3D Tissue Imaging and Analysis 用于三维组织成像和分析的激光消融断层扫描

Volume 3: Biomedical and Biotechnology Engineering Pub Date : 2019-11-11 DOI: 10.1115/imece2019-12282

Asheesh Lanba, B. Hall

{"title":"Laser Ablation Tomography for 3D Tissue Imaging and Analysis","authors":"Asheesh Lanba, B. Hall","doi":"10.1115/imece2019-12282","DOIUrl":"https://doi.org/10.1115/imece2019-12282","url":null,"abstract":"\u0000 Laser ablation tomography (LATscan) can produce 3D tissue models at micron-scale resolution within a few minutes, being amenable to high-throughput applications. The RGB images obtained from LATscan allow for enhanced and accurate feature segmentation and quantification. The technology uses an ultrafast, ultraviolet pulsed laser to continually ablate a sample as it is fed into the laser ablation plane. The ultrafast nature of the laser pushes the process into being athermal, minimizing structural damage to the material being imaged. The surfaces are imaged at the ablation plane. Precise motion control allows for sub-micron separation between consecutive images. The ablation results in color images due to the ultraviolet laser inducing multi-spectral fluorescence. The LATscan system can also be programmed allow for co-registration of cross-sections under different lighting conditions. The images are then stacked, further processed and reconstructed into volume renderings with a voxel size that can go down to 0.2 μm3 for further analysis and virtual dissection. Image processing allows for the 3D visualization and quantification of desired anatomy. LATscan has been successfully applied in the fields of plant science, entomology and materials science. It shows great promise for biomedical imaging and tissue analysis, and this paper presents a few results from the LATscan imaging of murine tissue. Various murine organs have been imaged, including the gut, kidney, and brain (inside the skull). The imaging and analysis combined have the potential to provide pathologists, researchers and diagnosticians with insights and solutions not available to them before.","PeriodicalId":332737,"journal":{"name":"Volume 3: Biomedical and Biotechnology Engineering","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114326559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Surgical Bone Drilling: A Review 外科骨钻孔:综述

Volume 3: Biomedical and Biotechnology Engineering Pub Date : 2019-11-11 DOI: 10.1115/imece2019-10945

C. Samarasinghe, M. Uddin, S. Bari, C. Xian

{"title":"Surgical Bone Drilling: A Review","authors":"C. Samarasinghe, M. Uddin, S. Bari, C. Xian","doi":"10.1115/imece2019-10945","DOIUrl":"https://doi.org/10.1115/imece2019-10945","url":null,"abstract":"\u0000 Bone drilling is an important step in orthopedic surgeries for the reconstruction and repair of fractured bones. The main concern in bone drilling is to create holes without causing minimum damage to the bone tissues. It is well reported that high temperature and high force in drilling cause bone thermal necrosis leading to the delayed bone healing and implant failure. In the past, a significant amount of research has been conducted to understand and mitigate the issues in bone drilling. However, the current practice in bone drilling is that medical surgeons still rely on their own experience and feeling, which often causes unwanted damage to the bone. The present paper aims to provide a comprehensive review of surgical bone drilling and impending factors affecting drilling and biological performance of the bone. Current protocols and practices in tackling issues around drilling are discussed and assessed in terms of results obtained in both experimental and computational domains. This pragmatic discussion will signify the importance and challenges ahead in empowering medical surgeons to enable improved surgical outcome. Furthermore, the findings of this extensive review are expected to drive further exploration of new opportunities for developing advanced bone drilling system integrated with intelligent sensors and control technology.","PeriodicalId":332737,"journal":{"name":"Volume 3: Biomedical and Biotechnology Engineering","volume":"220 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127527882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

A Study of Concussions in Women’s Lacrosse 女子曲棍球运动员脑震荡的研究

Volume 3: Biomedical and Biotechnology Engineering Pub Date : 2019-11-11 DOI: 10.1115/imece2019-12024

Peyman Honarmandi, L. Toscano, Michael A. Calicchia, M. Díaz, Emma Kaishian, W. Stallings

{"title":"A Study of Concussions in Women’s Lacrosse","authors":"Peyman Honarmandi, L. Toscano, Michael A. Calicchia, M. Díaz, Emma Kaishian, W. Stallings","doi":"10.1115/imece2019-12024","DOIUrl":"https://doi.org/10.1115/imece2019-12024","url":null,"abstract":"\u0000 Concussions in athletes can be brought on by a hit to the head or sudden change in direction of the neck or head. This causes the brain to oscillate in the cranium hitting against the skull. Two common scenarios that result in a concussion in women’s lacrosse were studied: lacrosse ball to head contact and stick to head contact. Current Manhattan College student athletes on the Women’s Lacrosse team were used to obtain data regarding the average velocity of the ball, stick, and players. A pitching machine was utilized to accurately control the velocity of the ball when striking the dummy’s head to obtain the time of impact. The first step of this research is computational, as the collision scenarios were modeled and analyzed from a mechanical point of view. A linear acceleration value was obtained for a wide range of potential impact scenarios between the ball and player. When a linear acceleration greater than 50g is sustained, a concussion is likely to occur. The maximum linear acceleration calculated in this research was roughly 75.46g for ball to head contact and 62.3g for stick to head contact. Therefore, it was concluded that there is a high risk that a player will suffer a concussion in these scenarios. The results highlight the dangers in a gameplay setting, which indicates a potential need for alteration to game play style or regulations.","PeriodicalId":332737,"journal":{"name":"Volume 3: Biomedical and Biotechnology Engineering","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125593407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Method for Approximating the Mechanical Section Properties of Structural Members With Highly Complex Cross-Sections 一种高度复杂截面结构构件力学截面特性的近似方法

Volume 3: Biomedical and Biotechnology Engineering Pub Date : 2019-11-11 DOI: 10.1115/imece2019-10445

W. P. Munsell

引用次数: 0

Effect of Motion Type on Joint Contact Forces 运动类型对关节接触力的影响

Volume 3: Biomedical and Biotechnology Engineering Pub Date : 2019-11-11 DOI: 10.1115/imece2019-10980

A. Schmitz, Jaclyn D. Norberg

{"title":"Effect of Motion Type on Joint Contact Forces","authors":"A. Schmitz, Jaclyn D. Norberg","doi":"10.1115/imece2019-10980","DOIUrl":"https://doi.org/10.1115/imece2019-10980","url":null,"abstract":"\u0000 Race walking has grown over the past decade because it provides exercise without the high impact loads of running. In fact, race walking has been shown to result in decreased ground reaction forces. We predict these lower ground reaction forces will extend to knee joint loading as well, thus explaining the decrease rate of knee osteoarthritis in race walkers compared to runners. This is a secondary analysis of instrumented motion capture data collected from fifteen competitive race walkers as they ran and race walked over a force plate. A Visual3D to OpenSim pipeline was used to create muscle actuated forward dynamics simulations of race walking and running. The resulting muscle forces were subsequently used to actuate a discrete element knee model to calculate joint forces. The peak tibiofemoral joint contact load during race walking was 18% lower than the load during running. This load was distributed between the medial and lateral compartments such that the medial load was 27% lower and the lateral load 35% lower in race walking. This suggests race walking is a lower impact exercise safer for the joints. This may be advantageous for people who would like to exercise at a higher intensity that walking provides but have joint problems, e.g. those with osteoarthritis.","PeriodicalId":332737,"journal":{"name":"Volume 3: Biomedical and Biotechnology Engineering","volume":"113 5 Suppl 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130420556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Highly Porous Shape Memory Nanocomposites for Applications in Biomedical Devices 高度多孔形状记忆纳米复合材料在生物医学器件中的应用

Volume 3: Biomedical and Biotechnology Engineering Pub Date : 2019-11-11 DOI: 10.1115/imece2019-10514

Jishan Luo, Robert Kunkel, Jingyu Wang, B. Bohnstedt, M. Saha, Yingtao Liu, Chung-Hao Lee

{"title":"Highly Porous Shape Memory Nanocomposites for Applications in Biomedical Devices","authors":"Jishan Luo, Robert Kunkel, Jingyu Wang, B. Bohnstedt, M. Saha, Yingtao Liu, Chung-Hao Lee","doi":"10.1115/imece2019-10514","DOIUrl":"https://doi.org/10.1115/imece2019-10514","url":null,"abstract":"\u0000 This paper presents the novel development of highly porous carbon nanotube (CNT)/shape memory polymer (SMP) nanocomposites for potential endovascular treatment of intracranial aneurysms (ICAs). Intracranial aneurysm is a cerebrovascular disorder that can significantly weaken the wall of a brain artery, resulting in a localized dilation of the blood vessel with risk of rupture and subarachnoid bleeding. Current therapeutic options include surgical clipping and endovascular coil embolization. Clipping of intracranial aneurysms is invasive, and, therefore, it has gradually been replaced by non-invasive endovascular embolization. Recent studies have shown that aneurysmal recanalization and incomplete occlusion are still emerging clinical challenges in endovascular coil embolization. Therefore, there is an urgent need to develop new medical devices and surgical procedure to treat intracranial aneurysms with improved long-term outcomes.\u0000 CNT/SMP nanocomposites are fabricated by directly coating CNTs on sugar particles before fabricating the sugar template for porous nanocomposites. Pristine SMP prepolymer is infiltrated into the pores of sugar template. All the sugar is dissolved in water after the fully curing of PDMS, resulting in SMP based nanocomposites with well dispersed CNTs. The porous nanocomposites are characterized to identify key parameters, such as electrical resistivity and shape memory capability. A resistive-heating mechanism is developed to trigger shape recovery of the nanocomposites. The results of this work will lay a solid foundation for our subsequent development of new personalized biomedical devices to treat ICAs using a catheter-based endovascular embolization procedure.","PeriodicalId":332737,"journal":{"name":"Volume 3: Biomedical and Biotechnology Engineering","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131130394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1