N. Moorchung, A. Srivastava, N. Gupta, S. Bandopadhyay, B. R. Achyut, B. Mittal
{"title":"The Role Of Helicobacter Pylori And Cag A Antibody Titers In The Pathology Of Chronic Gastritis","authors":"N. Moorchung, A. Srivastava, N. Gupta, S. Bandopadhyay, B. R. Achyut, B. Mittal","doi":"10.5580/df3","DOIUrl":"https://doi.org/10.5580/df3","url":null,"abstract":"Chronic gastritis is a multifactorial disorder, which is influenced primarily by the bacterium Helicobacter pylori. In addition to the density of the organism, the CagA pathogenicity island (PAI) of H pylori is thought to be a primary factor contributing to the antral inflammation. Endoscopic findings are believed to be non contributory in the diagnosis. In this study, we have shown that endoscopic features like erythema, erosions and nodularity maybe contributory in predicting the presence of H pylori in the biopsy specimen. The primary factor influencing the degree of inflammation in gastritis appears to be the density of H pylori in the antrum. The CagA pathogenicity island does not appear to have a role in influencing the severity of the antral inflammation. The role of other H pylori antigens remains undetermined.","PeriodicalId":331725,"journal":{"name":"The Internet Journal of Tropical Medicine","volume":"47 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126761421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Linear Dermatitis Following Contact With the Rove Beetle In Nigerians: A Report of 2 Cases","authors":"O. Oyedeji, O. Adebami, G. Oyedeji","doi":"10.5580/1506","DOIUrl":"https://doi.org/10.5580/1506","url":null,"abstract":"Cutaneous reactions to insects are common in the tropics. They usually follow arthropod bites and are referred to as papular urticaria. Dermatological reactions following contact with only insect or insect fluid content, in the absence of bites are rare. We report the case of a secondary school pupil and a farmer with linear dermatitis following contact with the rove beetle and its body fluid. To our knowledge this is the first reported case, of this disease in Nigeria.","PeriodicalId":331725,"journal":{"name":"The Internet Journal of Tropical Medicine","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123828211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Renal Tubular Acidosis Presenting As Severe Hypokalemia With Respiratory Paralysis: Report Of Two Cases","authors":"I. Mishra, S. Mishra, S. Pati, D. Mohapatra","doi":"10.5580/1486","DOIUrl":"https://doi.org/10.5580/1486","url":null,"abstract":"Hypokalemia is usually asymptomatic and goes undetected. Or it may manifest as muscular weakness, fatigue, abdominal distension. Severe hypokalemia may lead to cardiac arrhythmias and even death. However, respiratory paralysis leading to hypoventilation and respiratory failure is uncommon and very rarely reported in the literature. We report two patients of hypokalemia with quadriplegia who developed respiratory paralysis and cyanosis, requiring ventilatory support. Both were diagnosed as cases of renal tubular acidosis.","PeriodicalId":331725,"journal":{"name":"The Internet Journal of Tropical Medicine","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126466073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Note On Survival Of Infective Stage Larva Of Gnathostoma Spp. In BME Culture Medium","authors":"S. Soogarun, J. Suwansaksri, V. Wiwanitkit","doi":"10.5580/1267","DOIUrl":"https://doi.org/10.5580/1267","url":null,"abstract":"Dear editor, human gnathostomiasis in an important tropical parasitic infection ( 1). The major manifestation as nodular migratory eosinophilic panniculitis is suggested for this disease. More severe presentations, resulting from visceral larva migran, such as ocular and CNS gnathostomiasis are also reported. The diagnosis is confirmed by identification of the parasite from the pathological specimen. However, it is difficult to get the histological diagnosis, therefore, the immunological diagnosis for this infection is necessary. At present, Gnathostoma spinigerum third stage larvae (L3) antigen is necessary for Western blot analysis in the diagnosis of Gnathostomiasis ( 2 , 3). Acid pepsin solution is required for digestion of eel's liver (Fluta alba) to yield the larvae for antigen preparation. However, the specific antigen is excretion secretory (ES) antigen, which can be derived from viable larva. Since the larva start to degenerate within a short period, therefore, the larva derived from digestion must be used before its death. Here, we reported our result in using the BME culture medium for cultivation of the derived larva to prolong the period of usage of the harvested larva in antigen preparation.","PeriodicalId":331725,"journal":{"name":"The Internet Journal of Tropical Medicine","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115213833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Contamination Of The Gnathostoma Spp Infective Stage Larvae In Fluta Alba Sold In Bangkok","authors":"Pongsatorn Kue-A-Pai, V. Wiwanitkit","doi":"10.5580/11c3","DOIUrl":"https://doi.org/10.5580/11c3","url":null,"abstract":"In Thailand Gnathostoma spinigerum is the major causative agent of human gnathostomiasis. Usually, humans acquire the infection by consumption of G. spinigerum L3s infected hosts as partially cooked or uncooked food. Of several uncooked food, the highest prevalence of G. spinigerum L3s was found in Fluta alba (swamp eels). In Thailand, data of the prevalence and concentration of the parasite in these second intermedate hosts are limited. To provide this basic public health information, study of the distribution of Gnathostoma infective larvae in second intermediate hosts is necessary. We report here the findings of a study of G. spinigerum L3s in the livers of swamp eels from several wandering eel selling stalls in Bangkok to fulfill those previous studies. A total of 368 viscera of swamp eels for this study were obtained from several wandering eel selling stalls in order to study the prevalence of contaminated gnathostome L3s. The prevalence of L3s contamination is 15 %. The average number of larvae recovered was about 0.02 larvae/g of liver. In addition, there were also other recovered parasites such as Acanthocephalans and minute flukes. the authors concluded that the contamination of L3 in the swamp eels in Thailand is high and can be seen in any selling sources or season although there are some previous reports on the setting or seasonal predominance of contamination. We hypothesize that the finding is due to the wide distribution of the swamp eels from the original sources to several selling places, markets and wandering stalls in Thailand. The better transportation system in Thailand at present can be solution of this finding.","PeriodicalId":331725,"journal":{"name":"The Internet Journal of Tropical Medicine","volume":"102 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125840025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T. Ogunlesi, J. Okeniyi, O. Oyedeji, S. B. Oseni, O. Oyelami, O. Njokanma
{"title":"Childhood Dysentery In Ilesa, Nigeria: The Unusual Role Of Entamoeba Histolytica","authors":"T. Ogunlesi, J. Okeniyi, O. Oyedeji, S. B. Oseni, O. Oyelami, O. Njokanma","doi":"10.5580/12f6","DOIUrl":"https://doi.org/10.5580/12f6","url":null,"abstract":"Background: Shigella species are the usual aetiologies of dysentery in the developing world while Entamoeba histolytica is regarded as uncommon in young children. Objective: To determine the prevalence of Entamoeba histolytica in childhood dysentery in Ilesa, Nigeria. Method: A cross-sectional survey of consecutive under-five children with bloody diarrhoeic stools. Fresh stool specimens were examined microscopically and also cultured on Desoxycholate Citrate Agar (DCA) and MacConkey Agar. Results: A total of 300 under-five children with diarrhoea were recruited out of which 41 had dysentery giving a prevalence of 13.7%. Trophozoites of Entamoeba histolytica were identified in 33 (80.5%) cases while Trichuris trichiuria and Shigella species were isolated in 1 (2.4%) and 4 (9.8%) cases respectively. No pathogens were identified in 2 (4.9%) cases. Conclusion: Entamoeba histolytica is a prominent aetiology of childhood dysentery in Ilesa, Nigeria.","PeriodicalId":331725,"journal":{"name":"The Internet Journal of Tropical Medicine","volume":"73 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127222613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Feasibility Of Using Orange Juice For Digestion Of Swamp Eel Viscera For Harvesting Infective Stage Larva Of Gnathostoma Spp.","authors":"Pongsatorn Kue-A-Pai, V. Wiwanitkit","doi":"10.5580/715","DOIUrl":"https://doi.org/10.5580/715","url":null,"abstract":"Gnathostoma spinigerum third stage larvae antigen is necessary for Western blot analysis in the diagnosis of Gnathostomiasis. Acid pepsin solution is required for digestion of eel's liver( Fluta alba ) to yield the larvae for antigen preparation. Here, he reported the feasibility of using orange juice as an alternative to enzyme pepsin in harvesting Gnathostoma spinigerum third stage larvae. From the experimental digestion, it was found that we could recover larvae from orange juice. Thus, orange juice might be another choice for recovering Gnathostoma spinigerum third stage larvae.","PeriodicalId":331725,"journal":{"name":"The Internet Journal of Tropical Medicine","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130760576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Isolated Tubercular Liver Abscess In Pediatric Age Group","authors":"A. Chaudhary, A. Wakhlu","doi":"10.5580/22cd","DOIUrl":"https://doi.org/10.5580/22cd","url":null,"abstract":"We report about two patients, the first 7 years and the second 10 years old presenting in our outpatient clinic with history of pain in right upper abdomen, high fever, anorexia and weight loss. A detailed search failed to identify any other focus of tubercular infection. Laparotomy was carried out in the first patient as the abscess was multiloculated and inaccessible to percutaneous aspiration. Antitubercular therapy was begun in the postoperative period when high fever persisted and polymerase chain reaction came out positive for Mycobacterium Tuberculosis. In the second patient diagnosis was made by enzyme linked immunosorbant assay but surgical drainage was done because percutaneous aspiration failed to drain the multiloculated abscess. Both the patients showed dramatic response with antitubercular therapy and gradually hepatomegaly regressed. Isolated hepatic tubercular liver abscess, though a very rare diagnosis should always be considered when signs and symptoms fail to improve with antiamoebic, antibacterial therapy and conventional surgical management.","PeriodicalId":331725,"journal":{"name":"The Internet Journal of Tropical Medicine","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133894164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Meher, R. Rajput, J. Passey, Ruchika Gupta, Sompal Singh
{"title":"Rhinosporidiosis Presenting As Nasal And Urethral Polyp","authors":"R. Meher, R. Rajput, J. Passey, Ruchika Gupta, Sompal Singh","doi":"10.5580/e79","DOIUrl":"https://doi.org/10.5580/e79","url":null,"abstract":"Rhinosporidiosis is a chronic granulomatous disease of mucous membranes and is endemic in South India and Sri Lanka. Although it predominantly affects nose and nasopharyngeal mucosa, other sites are also rarely affected. High index of suspicion and characteristic pathological feature are the mainstay of diagnosis for extra nasal infection. We describe a case of 35 year old north Indian male who presented with urethral polyp. Otorhinolaryngological examination revealed a nasal mass as well. Biopsy from both the urethral and nasal mass showed features of rhinosporidiosis. The aetiopathogenesis, clinical & pathological picture and management of the disease have been discussed.","PeriodicalId":331725,"journal":{"name":"The Internet Journal of Tropical Medicine","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130304899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prevalence Of Intestinal Parasites Among The Local People In Lum Pra Due Village, Nakornratchasrima, Thailand Without Previous History Of Antihelminthic Drug Distribution","authors":"J. Suwansaksri, V. Wiwanitkit, S. Nithiuthai","doi":"10.5580/1146","DOIUrl":"https://doi.org/10.5580/1146","url":null,"abstract":"A survey of prevalence of intestinal parasites among the local population of Lum Pra Due village in the Nakorn Ratchasrima province was performed during the year of 2000. The setting is a community in the endemic area of trematode infection without the recent previous history of antihelminthic drug distribution. Stool examination from 153 villagers (63 males and 90 females) was performed. The infection rate was 68 % (104 cases). The rate of infection in male (72 %) was higher than in female (62 %). Most of the infected cases (88 %) were in the age group 41 60 years. Single Opisthorchis viverrini infection was found in 7 cases. Combined infection of Opisthorchis viverrini with other non-fluke intestinal parasite was found in 44 cases. Combined infection of minute intestinal fluke with other non-fluke intestinal parasite was found in 85 cases. There were also 5 infected cases, but without fluke, with non-fluke parasite. Therefore, trematode infection is still a major health problem for this community.","PeriodicalId":331725,"journal":{"name":"The Internet Journal of Tropical Medicine","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129673123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}