The Internet Journal of Tropical Medicine最新文献

{"title":"Tuberculous Mastitis Masquerading As Carcinoma Breast","authors":"Aarati Ramesh Daryanani, P. Sundeep, G. Rodrigues, Sampath P. Kumar, Ranjini Kudva","doi":"10.5580/1dd8","DOIUrl":"https://doi.org/10.5580/1dd8","url":null,"abstract":"Extra-pulmonary tuberculosis occuring in the breast is relatively rare. We present such a case with literature review.","PeriodicalId":331725,"journal":{"name":"The Internet Journal of Tropical Medicine","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2002-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124981164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Images from Tropics","authors":"A. Sachdev, A. Bhalla, Ram Singh, S. Lehl, S. Cruz","doi":"10.5580/41f","DOIUrl":"https://doi.org/10.5580/41f","url":null,"abstract":"CASE REPORT A middle-aged male, presented with symptoms suggestive of malabsorption syndrome. Examination revealed an emaciated man with glossitis, cheilitis, angular stomatitis and significant pedal oedema. He had megaloblastic anemia, 8% eosinophils & hypoalbuminemia. Stool examination showed larvae of Strongyloides stercoralis. D-Xylose test had a value of 0.7g/5g after 5 hours of urine collection. Barium meal follow through revealed thickened duodenal and jejunal folds with irritability and decreased transit time. Endoscopic biopsy from third part of the duodenum showed the larvae of strongyloides stercoralis infiltrating the surface and crypt epithelium (Photomicrograph). HIV serology (HIV 1 & 2) by ELISA was negative. He was treated successfully with Thiabendazole 25 mg/kg/day for three days. On followup after 6 weeks, his diarrhoea had subsided and he had gained weight. Strongyloides stercoralis in an immunocompetent patient is an unusual but a potentially treatable cause of malabsorption in tropics. Figure 1 Photomicrograph: Strongyloides stercoralis larvae, seen in the intestinal crypt epithelium in a patient with malabsorption. CORRESPONDENCE TO Dr. A. Bhalla. 1032, Sector 24 B, Chandigarh. India. Phone 91-172-230109 E mail. atulsachdev@glide.net.in ab_chd@hotmail.com lehlss@yahoo.com sdcruz@yahoo.com References","PeriodicalId":331725,"journal":{"name":"The Internet Journal of Tropical Medicine","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2002-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116775935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Developments In Hepatitis Delta Research","authors":"C. Cunha, N. Freitas, S. Mota","doi":"10.5580/10","DOIUrl":"https://doi.org/10.5580/10","url":null,"abstract":"The hepatitis delta virus (HDV) is the smallest human pathogen known so far. Several characteristics of the virus RNA genome resemble that of plant viroids. Since the hepatitis B virus surface antigens are part of the HDV envelope and are necessary for productive infection, HDV may be considered a satellite virus of HBV. Coinfection of the two viruses or superinfection with HDV in HBV carriers increases the risk of fulminant hepatitis and development of liver cirrhosis. At present, there is no specific treatment for hepatitis D. However, vaccination against HBV confers protection against coinfection with HDV. Although the increased rate of vaccination against HBV in developed countries reduced the prevalence of HDV, it is still a threat and remains endemic in many regions of the world. Here, we overview the epidemiology and treatment of hepatitis delta and report recent advances in the research of HDV biology. CLINICAL AND EPIDEMIOLOGICAL FEATURES The hepatitis delta virus (HDV) was discovered by the italian gastroenterologist Mario Rizzetto while studying liver biopsies of hepatitis B virus (HBV) infected patients (Rizzetto et al., 1977). Later, it was shown that HDV infects individuals previously infected with HBV, causing more severe hepatic lesions, and increasing the risk of fulminat hepatitis (Gorinvadarajan et al., 1984; Jacobson et al., 1985). Since the presence of HBV is necessary for the production of infectious HDV particles capable of propagating the infection, the HDV may be considered a HBV satellite virus (Rizzetto et al., 1980; Ponzetto et al, 1988). The clinical association between these two viruses is due to the fact that the genome of HDV does not encode for its own envelope proteins. The HDV envelope consists of HBV surface proteins (HBsAg; Smedile et al., 1994), and as a consequence HDV transmission occurs only in the presence of HBV. HDV replication seems to occur only in the liver, and all pathological abnormalities are limited to this organ. The lesions are similar to those observed during the course of other acute and chronic viral hepatitis. Often they consist of hepatocellular necrosis and inflamation. From the histological point of view, there are no significant differences between lesions caused by HDV and those caused by other hepatitis viruses. The clinical course of HDV infection may be variable. In general, the observed symptoms are more severe than those associated with other hepatitis viruses. The incubation period varies between 3 to 7 weeks. Following this period, the first symptoms can be detected, including fatigue, lethargy, and nausea. It is estimated that 60% to 70% of all hepatitis delta chronic patients will develop chirrosis. This percentage is about three times higher when compared to the percentage that is observed in hepatitis B patients (Rizzetto et al., 1983). The frequency of HDV associated fulminant hepatitis, the more severe form of the acute disease, is 10 times higher than the observed for ot","PeriodicalId":331725,"journal":{"name":"The Internet Journal of Tropical Medicine","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2002-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127994893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Translation of the Parents’ Evaluation of Developmental Status (PEDS) Developmental Screening Tool for Identification of Developmental Delay in Children from Birth to Five Years of Age in the Karagwe District of Northwestern Tanzania, East Africa: A Pilot Study","authors":"M. Novak","doi":"10.5580/1cd0","DOIUrl":"https://doi.org/10.5580/1cd0","url":null,"abstract":"","PeriodicalId":331725,"journal":{"name":"The Internet Journal of Tropical Medicine","volume":"53 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121579061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}