{"title":"Summary On The Prevalence Of Serum VCA-IgA Antibody Among Thai Patients With Lymphoma: An Implication For Risk And Screening Purpose","authors":"V. Wiwanitkit","doi":"10.5580/161c","DOIUrl":"https://doi.org/10.5580/161c","url":null,"abstract":"Lymphoma is a common hematological malignancy. Relationship with the Epstein-Barr virus (EBV) was indicated. Anti-EBV serology, immunoligcal test for detection of EBV infection is applied for screening and detection of lymphoma. Of several tests, lgA antibody to viral capsid antigens of Epstein-Barr virus (VCA-lgA antibody) has been mentioned as a valuable test for screening for and early detection of lymphoma. Here, the author performs an appraisal on the prevalence of serum VCA-lgA antibody among Thai patients with lymphoma comparing with healthy control subjects. According to the literature review, 2 reports [6, 7] were recruited for further metanalysis. According to the metanalysis, 39 cases and 252 healthy subjects were investigated for serum VCA-lgA antibody. The overall antibody positive rate in the patients and healthy subjects are 35.9 % (14/39) and 2.4 % (6/252), respectively. The odds ratio is 22.96. According to this study, it could be seen that having serum VCA-lgA antibody positive is a very high risk for lymphoma. Of interest, although the lymphoma is high prevalent in Thailand there is no specific recommendation in screening for this disease in high risk population. According to this study, the results suggested that the EBV-specific serum IgA antibodies might be a useful screening test for the cancer in people of high risk.","PeriodicalId":331725,"journal":{"name":"The Internet Journal of Tropical Medicine","volume":"243 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122634556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Novel Method of Identifying Micro & Macro Filarial Nematodes","authors":"A. Chandrasekaran, S. Vaseekaran","doi":"10.5580/6fc","DOIUrl":"https://doi.org/10.5580/6fc","url":null,"abstract":"INTRODUCTION The recent outbreak of Wuchereriasis Bancrofti infections in Southern areas of Tamil Nadu has resulted in a number of various manifestations in all age groups and both sexes irrespective of economic status and sanitary conditions. The onset of monsoon coincides with heavy mosquito spread both Anopheles and Culex species in all areas of localities. The range of manifestations starts from cutaneous, lymphatic, serous cavities and various other systems also. The pediatric age group is particularly vulnerable so also the rest of community. CLINICAL STUDY The picture of Wuchereriasis range from itchy dermatitis, lymphorrhea to pulmonary symptoms, central nervous system involvement, cardiac picture with chest pain, dyspnea and gastrointestinal pain, vomiting, fever and gentiurinary picture of severe dysuria, hematuria, chyluria, dysmonorrhea., abortions, still births and suspected intrauterine transfer to foetus also. MISNOMERS A number of cases missed and wrongly diagnosed and treated as tuberculosis, meningo-encephalitis, malignancies, myocardial Infarcts, asthmas, arthritis.. COMMON PITFALLS OF DIAGNOSIS The time honored teaching of peripheral blood smear study should be done to coincide with periodicity – nocturnal after 10 p.m to 2 a.m has resulted in missing so many cases of Filariasis in all localities. Our study aimed at finding the parasites in peripheral blood and saliva, urine, sputum, serosanguinous discharges, semen, vaginal fluids and CSF. METHODOLOGY A novel PVC sheet treated with Na3N salt acts as a very good medium to trap, entice the parasites both Micro & Macro Filariae. The same PVC sheet gives blue coloration to Male and red color to Female adult parasites in blood, tissues and various other fluids. The treated PVC sheet used as a cover slip gives positive results done at any time of the day both day and night. The other old method of Wright’s, Giesma stain were not needed here. The technique is able to preserve the specimen for more than 48 hours also. CONCLUSION The tropical disease masquerading in Asian, African continents wreaking havoc in local populations has to be tackled on a war footing. The identification of cases both occult and clinical can be very much enhanced to a great extent both technically and financially simpler with this new treated PVC technique. CLINICAL PHOTOGRAPHS Figure 1 Figure 1: Adult Male and Female MF in blood A Novel Method of Identifying Micro & Macro Filarial Nematodes 2 of 4 Figure 2 Figure 2: Microfilariae in blood Figure 3 Figure 3: MF in urine Figure 4 Figure 4: MF in sputum Figure 5 Figure 5: MF adult female in partutition A Novel Method of Identifying Micro & Macro Filarial Nematodes 3 of 4 Figure 6 Figure 6: Moulted MF in Anopheles mosquito mouth part. All photographs were done with Na3N treated PVC cover slips. Note: The treated PVC sheet is an invention of us from Na3N salt technology. References A Novel Method of Identifying Micro & Macro Filarial Nematodes 4 of 4 Author Info","PeriodicalId":331725,"journal":{"name":"The Internet Journal of Tropical Medicine","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133492238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Summary Of Hydatid Disease In Thailand","authors":"Viroj Wiwanitki","doi":"10.5580/152a","DOIUrl":"https://doi.org/10.5580/152a","url":null,"abstract":"Context: Hydatid disease is a zoonosis caused by the tapeworm of Echinococcus spp. In Southeast Asia, the human hydatid disease is rare. Objective: The author performed a literature review on the reports of hydatid diseases in Thailand in order to summarize the characteristics of this infection among those patients. Design: This study was designed as a descriptive retrospective study. A literature review of the papers concerning hydatid diseases in Thailand was performed. Results: According to this study, there have been at least 10 reports in the literature of hydatid diseases, with 2 lethal cases. Of these 10 cases, 6 were males and 4 were females. Of 9 cases that documented patients' age, the ages ranged from 16 years to 58 years. Lung cyst is the most common manifestation (6 cases), following by liver cyst (2 cases), kidney cyst (1 case) and peritoneal cyst (1 case), orderly. All cases were accidentally detected from histological examination of surgical or autopsy specimens. Most (90%) were identified as E. granulosus infection; however, there was 1 case with E. multilocularis infection. Surgical removals were performed in all except 1 case. Antiparasitic drugs were prescribed in 5 cases: albendazole in 3 cases and albendazole with praziquantel in 2 case. Concerning the two lethal cases, one had neither surgical removal nor antiparasitic drug, the other had both surgical removal and antiparasitic drug but there was accidental rupture of the cyst during surgery. Conclusion: In conclusion, the hydatid disease is a rare cestode infection that is sporadically reported in Thailand. The surgical removal seems to be still an effective method for treatment.","PeriodicalId":331725,"journal":{"name":"The Internet Journal of Tropical Medicine","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131386470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Phthiriasis Palpebrarum: An Unusual Presentation Of Blepharitis","authors":"N. Momaya, P. Doctor, Rahul P Doctor","doi":"10.5580/1560","DOIUrl":"https://doi.org/10.5580/1560","url":null,"abstract":"Described is a case report of a 30 year old man presenting with symptoms suggestive of Blepharitis. On examination he was diagnosed to be a case of Phthiriasis Palpebrarum, which is an unusual presentation of Blepharitis.","PeriodicalId":331725,"journal":{"name":"The Internet Journal of Tropical Medicine","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132839968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Puneet, S. Tiwary, R. Ragini, Sanjay Singh, S. Gupta, V. Shukla
{"title":"Breast Tuberculosis: Still Common In India","authors":"Puneet, S. Tiwary, R. Ragini, Sanjay Singh, S. Gupta, V. Shukla","doi":"10.5580/af8","DOIUrl":"https://doi.org/10.5580/af8","url":null,"abstract":"Breast tuberculosis is a rare form of tuberculosis. In last three years 1016 patients of breast lump were referred to single unit of pathology department. FNAC was performed in all the cases and 770 patients (75%) were diagnosed as benign breast disease while 246 patients (25%) were malignant. Out of 770 cases of benign disease, 42 patients (4.13%) had tuberculosis of breast. The mean age of the patient with tuberculosis was 33.71 year. 41 patients were female and one was male. 8 patients (19.04%) were lactating at the time of presentation. Most of these lumps were clinically misdiagnosed as benign breast disease (29cases) or malignancy (8 cases). In conclusion, although breast tuberculosis is extremely rare in developed countries but it is still common in developing countries like India. The diagnosis can be easily made from the FNAC of the suspected lump.","PeriodicalId":331725,"journal":{"name":"The Internet Journal of Tropical Medicine","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131850872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cysticercosis Of The Cheek","authors":"R. Meher, A. Sabherwal","doi":"10.5580/21c4","DOIUrl":"https://doi.org/10.5580/21c4","url":null,"abstract":"The cheek is a rare site for cysticercosis cellulosae. Very few cases of solitary cysticercosis of cheek have been reported. We report one such case and discuss the review of literature, etoipathogenesis, clinical course and management.","PeriodicalId":331725,"journal":{"name":"The Internet Journal of Tropical Medicine","volume":"2023 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115403092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"High Prevalence Of Filariasis In Myanmar-Migrant Workers From Screening Program Of A Local Hospital In A Rural District Of Southern Thailand","authors":"V. Wiwanitkit","doi":"10.5580/751","DOIUrl":"https://doi.org/10.5580/751","url":null,"abstract":"Background: Although the present prevalence of filariasis in the Thai population is low, migration of Myanmar labor into Thailand may increase the incidence of bancroftian filariasis. Due to the previous report, the prevalence of filariasis in Myanmar-migrant workers was very high. In this study, we reported the prevalence of lymphatic filariasis in Myanmar-migrant workers in Bangsaparn district, Prachuab Kiri Khan, a rural community in the Southern Region of Thailand with the high density of Myanmar-migrant workers as fishermen. Methods: We analyzed the data of screening for filariasis using microscopic examination among 250 Myanmar-migrant workers (169 males and 81 females) who had just stayed in Thailand for less than 1 month. Results: The microfilarial rate among these Myanmar migrants was 2.4 %. All cases were bancroftian filariasis. The microfilarial rates in males and females were 3.0% and 1.2 %, respectively. Conclusion: Since these migrants carry the parasite with high infected rate and the mosquito vector Culex quinquefasciatus is also prevalent in Thailand, Thai people are at high risk of acquiring this disease if good control and prevention strategies are not implemented. Filaria screening test as one of the infection control strategies is necessary. Presented at the Joint International Tropical Medicine Meeting 2001 Bangkok Thailand August 8 10, 2001","PeriodicalId":331725,"journal":{"name":"The Internet Journal of Tropical Medicine","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114284968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hematuria Is Common In The Fatal Cases Of Dengue Hemorrhagic Fever","authors":"V. Wiwanitkit","doi":"10.5580/d42","DOIUrl":"https://doi.org/10.5580/d42","url":null,"abstract":"Dengue infection is an important mosquito-borne infectious disease. This disease is common in the tropical countries, especially Southeast Asian countries. A severe form of dengue infection called dengue hemorrhagic fever (DHF) requires hospitalization. Thrombocytopenia and hemoconcentration are the hallmark of the DHF. The urological complications in DHF are not common. There are only a few reports concerning the magnitude and pattern of urological manifestration among fatal DHF cases. Here, the author analyzed the magnitude and pattern of the urological manifestration among the death Thai DHF cases. Here, the author performed this mini-study in order to document the magnitude and pattern urologicalpathology among reported Thai fatal DHF cases. A literature review on the papers concerning magnitude and pattern of urological manifestration among reported Thai fatal DHF cases was performed from database of the published works cited in the Index Medicus and Science Citation Index and also the published works in all 256 local Thai journals, which are not included in the international citation index. The reports that contained no complete data were excluded for further analysis. According to this review, there were 4 reports [1,2,3, 4] covering 51 Thai fatal DHF cases from total 6,154 DHF cases. Of the fatal cases, 5 cases had urological uroligcal manifestation, giving the incidence rate equal to 9.8 % among fatal DHF cases and 0.08 % among all DHF cases. Concerning the reported urological manifestration, all presented with frank hematuria. Here, it can be said that hematuria is common in fatal DHF, hence, presentation of hematuria might imply severe DHF.","PeriodicalId":331725,"journal":{"name":"The Internet Journal of Tropical Medicine","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129045681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Note On The Total Antioxidant Activity In The Subjects With Glucose-6-Phosphate Dehydrogenase Deficiency","authors":"A. Palasuwan, S. Soogarun, V. Wiwanitkit","doi":"10.5580/1821","DOIUrl":"https://doi.org/10.5580/1821","url":null,"abstract":"Glucose-6-phosphate dehydrogenase (G6PD) deficiency is a common inherited enzyme deficiency. This disorder causes hemolytic anemia, which is often enhanced by an identifiable chemical trigger or infection [1,2]. G6PD is the key rate-limiting enzyme in the pentose pathway and the expression of its gene has been shown to be redox-sensitive [3] Physiologically, G6PD plays an important role in cellular redox homeostasis, which is crucial for cell survival [4]. Cheng et al said that G6PD status determined the response of cells exposed to nitric oxide (NO) donor [4]. Overexpression of G6PD in vascular endothelial cells decreases reactive oxygen species accumulation in response to exogenous and endogenous oxidant stress and improves levels of bioavailable NO [5]. Here the authors investigated the antioxidant activity in a sample of healthy subjects comparing to subjects with G6PD deficiency. A total of 21 volunteer subjects were included into this investigation. All were screened for the G6PD deficiency by a biochemical assay kit 345 – A, (Sigma Co.) and 2 were detected to have G6PD deficiency. All were studied for the antioxidant activity by the Trolox equivalent antioxidant capacity (TEAC) method []. The average antioxidant activity in the healthy subjects and subjects with G6PD deficiency are 3.35 ± 0.27 mM Trolox equivalent and 3.17 ± 0.05 mM Trolox equivalent respectively. It seems that the antioxidant level in the subjects with G6PD deficiency might not different from the healthy subjects. However, the number of subjects in this study is rather few. Further larger study is recommended before final conclusion.","PeriodicalId":331725,"journal":{"name":"The Internet Journal of Tropical Medicine","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121540117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cytomorphology Of Hydatid Disease","authors":"U. Handa, A. Bal, H. Mohan","doi":"10.5580/11f2","DOIUrl":"https://doi.org/10.5580/11f2","url":null,"abstract":"We present a case of hydatid disease and conclude that in a patient with a presumptive diagnosis of cystic hydatid disease, FNA is the primary method of confirming hydatid disease.","PeriodicalId":331725,"journal":{"name":"The Internet Journal of Tropical Medicine","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122284165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}