Folia Medica Indonesiana最新文献_第9页

Urogenital Fistula Patients Profile at a Tertiary Hospital in Surabaya, Indonesia from 2015 to 2021 2015年至2021年印尼泗水一家三级医院泌尿生殖道瘘患者概况

Folia Medica Indonesiana Pub Date : 2022-09-05 DOI: 10.20473/fmi.v58i3.34903

M. Jamhari, M. Soebadi, J. Renaldo

{"title":"Urogenital Fistula Patients Profile at a Tertiary Hospital in Surabaya, Indonesia from 2015 to 2021","authors":"M. Jamhari, M. Soebadi, J. Renaldo","doi":"10.20473/fmi.v58i3.34903","DOIUrl":"https://doi.org/10.20473/fmi.v58i3.34903","url":null,"abstract":"Highlights:\u0000\u0000Vesicovaginal fistula is the most common urogenital fistula.\u0000The transvaginal approach is preferred in treating urogenital fistula.\u0000\u0000Abstract:\u0000A fistula is an extra-anatomical channel between two or more hollow organs, or between an organ and the body surface. WHO estimated there were two million patients with untreated urogenital fistula, with 130,000 new cases every year. The ideal approach for urogenital fistula depends on surgeon preference and individual clinical characteristics. Accordingly, we aimed to determine the profile of patients with a urogenital fistula at a tertiary hospital of Dr. Soetomo General Academic Hospital in Surabaya, Indonesia, from 2015 to 2021. A retrospective study with a descriptive design was carried out by medical records data retrieval of patients with urogenital fistula. It included age, etiology, anatomical location, surgical management, and recurrence rate. The study population consisted of 55 patients. The majority of the patients were among the 41-50 y.o. age groups (41.17%), while the least were in the <20 years group (1.96%). History of obstructed labor was the most common etiology (70.59%). Fistulas in the study population were also associated with a history of trauma (15.68%) and malignancy (11.76%). The vesicovaginal fistula was the most common type of fistula (88.23%). Other types found include urethrovaginal, ureterovaginal, rectovesical, rectovaginal, and vesicocolon fistulas. The transvaginal approach was preferred in almost all study populations. A total of two cases of vesicovaginal fistula recurred (3.39%). In general, patients with urogenital fistula are prevalent in the 4th decade age group, with the most common etiology being a history of obstructed labor. Transvaginal surgery is the treatment of choice with good results and low recurrence rates.","PeriodicalId":32666,"journal":{"name":"Folia Medica Indonesiana","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44242767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Risk Factors of Central Obesity in Indonesian Men: A Cross-Sectional Data Study of The Indonesia Family Life Survey 5 (IFLS 5) 印尼男性中心性肥胖的危险因素：印度尼西亚家庭生活调查5（IFLS 5）的横断面数据研究

Folia Medica Indonesiana Pub Date : 2022-09-05 DOI: 10.20473/fmi.v58i3.35778

Dahlia, Gracia Satyawestri Pribadi, S. Martini, Chung Yi-Li

{"title":"Risk Factors of Central Obesity in Indonesian Men: A Cross-Sectional Data Study of The Indonesia Family Life Survey 5 (IFLS 5)","authors":"Dahlia, Gracia Satyawestri Pribadi, S. Martini, Chung Yi-Li","doi":"10.20473/fmi.v58i3.35778","DOIUrl":"https://doi.org/10.20473/fmi.v58i3.35778","url":null,"abstract":"Highlights:\u0000\u0000Low levels o physical activity are the major risk factor of central obesity among Indonesian men.\u0000There was a relationship between smoking status, smoker type, cigarette type, physical activity, and meat consumption frequency and the incidence of central obesity.\u0000\u0000 \u0000Abstract:\u0000Obesity is one of the leading health problems in both developed and developing countries. Central obesity can be defined as a condition where excess fat has accumulated in the abdominal area. There are several risk factors that may cause central obesity in men such as smoking habits, physical activity, and dietary habits. This study aimed to analyse the risk factors of central obesity in Indonesian men. This was an analytical observational study using a cross-sectional design. It used secondary data from the Indonesia Family Life Survey (IFLS 5) with a sample size of 4,648 respondents. The variables studied here were smoking status, type of smoker, type of cigarette, physical activity, and meat consumption frequency. Logistic regression analysis was used. The results of this study showed that the mean age of the respondents was 51 years old. There was a relationship between smoking status (p=0.000), type of smoker (p=0.002), type of cigarette (p=0.000), physical activity (p=0.000), and meat consumption frequency (p=0.024) and the incidence of central obesity. The conclusion of the study was that there was a relationship between smoking status, type of smoker, type of cigarette, physical activity, meat consumption frequency, and the incidence of central obesity, all of which were risk factors of central obesity in Indonesian men. A low level of physical activity was the most prominent risk factor associated with central obesity among Indonesian men. From this study, we suggested controlling the risk factors of central obesity by providing education on the dangers of smoking and the importance of physical activity and a balanced nutritional diet.","PeriodicalId":32666,"journal":{"name":"Folia Medica Indonesiana","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49518213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diagnosis and Management of Adrenal Crisis in 46XX Congenital Adrenal Hyperplasia Infant 46XX先天性肾上腺增生婴儿肾上腺危象的诊断与处理

Folia Medica Indonesiana Pub Date : 2022-09-05 DOI: 10.20473/fmi.v58i3.14891

N. Rochmah, M. Faizi, N. P. Kusumastuti, L. F. M. Samadhi, W. Deakandi

{"title":"Diagnosis and Management of Adrenal Crisis in 46XX Congenital Adrenal Hyperplasia Infant","authors":"N. Rochmah, M. Faizi, N. P. Kusumastuti, L. F. M. Samadhi, W. Deakandi","doi":"10.20473/fmi.v58i3.14891","DOIUrl":"https://doi.org/10.20473/fmi.v58i3.14891","url":null,"abstract":"Highlight:\u0000\u0000The diagnosis and therapy of Congenital Adrenal Hyperplasia (CAH) children with Adrenal crisis (AC) case report.\u0000Adrenal crisis (AC) is a life-threatening emergency that contributes to the high death rate of children with adrenal insufficiency.\u0000The early detection and prompt treatment can improve the outcomes of patients with CAH and AC.\u0000\u0000 \u0000Abstract:\u0000Adrenal crisis is the acute complication of the patient with congenital adrenal hyperplasia. Congenital adrenal hyperplasia (CAH) is a rare condition. Children with CAH commonly come to the emergency room due to acute complications. The condition has high mortality and thus needs early recognition. Newborn screening for CAH in Indonesia is not routinely performed and has not been suggested yet. The purpose of this case report was to report a case of adrenal crisis in a congenital adrenal hyperplasia patient focused on diagnosis and therapy. A female, 10 months old infant, was admitted to the emergency department with a chief complaint of a decrease of consciousness for 3 hours before admission and frequent vomiting since born. On physical examination, there was clitoromegaly. Laboratory showed 17-OH progesterone: 173 ng/dL (7-77 ng/dL) and karyotyping: 46 XX. Management of adrenal crisis is a stress dose of hydrocortisone and rehydration. Education is the key to optimal outcomes and normal growth and development.","PeriodicalId":32666,"journal":{"name":"Folia Medica Indonesiana","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42562967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Risk Factors of Urinary Tract Infections Caused by Extended-Spectrum Β-Lactamase-Producing Escherichia Coli in Inpatients at a Tertiary Hospital In Surabaya, Indonesia 印度尼西亚泗水某三级医院住院患者广谱Β-Lactamase-Producing大肠杆菌引起尿路感染的危险因素

Folia Medica Indonesiana Pub Date : 2022-09-05 DOI: 10.20473/fmi.v58i3.15982

Ishak Samuel Wuwuti, Kuntaman, E. Wasito

{"title":"Risk Factors of Urinary Tract Infections Caused by Extended-Spectrum Β-Lactamase-Producing Escherichia Coli in Inpatients at a Tertiary Hospital In Surabaya, Indonesia","authors":"Ishak Samuel Wuwuti, Kuntaman, E. Wasito","doi":"10.20473/fmi.v58i3.15982","DOIUrl":"https://doi.org/10.20473/fmi.v58i3.15982","url":null,"abstract":"Highlights:\u0000\u0000ESBL frequency in women was higher than in men.\u0000Catheter use in patients with urinary tract infections and recurrent urinary tract infections has four times the risk of ESBL caused by Escherichia coli bacteria\u0000ESBL-producing E.coli bacteria are resistant to amoxicillin-clavulanic, ceftazidime, aztreonam, and ceftriaxone.\u0000\u0000Abstract:\u0000The incidence of urinary tract infections (UTIs) caused by extended-spectrum beta-lactamase (ESBL) producing Escherichia coli (E. coli) bacteria has become a global problem and has increased in recent years. The purpose of this study was to analyze the risk factors for the incidence of UTI in inpatients at Dr. Soetomo General Academic Hospital Surabaya. This research was an analytic descriptive study. Specimens were sent to the Clinical Microbiology Laboratory using sterile containers and processed according to standard laboratory procedures. It resulted in ESBL-producing E. coli that were used as a case group and non ESBL-producing E. coli as a control group. The identification and testing of antibiotic susceptibility were carried out using the BD Phoenix™ Automated Microbiology System. Ninety-four bacterial isolates were collected, consisting of 54 (57.4%) ESBL-producing E. coli bacteria and 40 (42.6%) non ESBL-producing E. coli bacteria. Recurrent UTIs (OR = 4.31; ρ =0.002; 95% CI = 1.68-11.04) and catheter use (ρ = 0.049; OR = 4.250; 95% CI = 1.050-17.210) were used as independent risk factors caused by ESBL-producing E. coli bacteria. Recurrent UTIs and catheter use were dependent risk factors caused by ESBL-producing E. coli bacteria.","PeriodicalId":32666,"journal":{"name":"Folia Medica Indonesiana","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44972836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hookworm in Stray Cats (Felis silvestris catus) as Cutaneous Larva Migrant Agent (CLM) in Humans 流浪猫(Felis silvestris catus)的钩虫作为人类皮肤幼虫迁移因子(CLM)

Folia Medica Indonesiana Pub Date : 2022-09-05 DOI: 10.20473/fmi.v58i3.28645

Fadhil Ihsan Mahendra, Soebaktiningsih Soebaktiningsih, Risma Karlina Prabawati

{"title":"Hookworm in Stray Cats (Felis silvestris catus) as Cutaneous Larva Migrant Agent (CLM) in Humans","authors":"Fadhil Ihsan Mahendra, Soebaktiningsih Soebaktiningsih, Risma Karlina Prabawati","doi":"10.20473/fmi.v58i3.28645","DOIUrl":"https://doi.org/10.20473/fmi.v58i3.28645","url":null,"abstract":"Highlights :\u0000\u0000Risk factors that can increase the incidence of CLM in humans include male sex, children aged <15 years, low-income people, and daily behaviour of walking outdoors without using footwear, especially on the sand.\u0000Risk factors that play the most role in increasing the incidence of CLM in humans are walking outdoors without using footwear, especially on the sand.\u0000\u0000 \u0000Abstract :\u0000Cats arethe host of a wide variety of microorganisms including ectoparasites and endoparasites.One of theendoparasites that infect cats is hookworm. The hookworms consists of two groups, the animal hookworms, and the human hookworms. The manifestation that can be caused by animal hookworms to humans is Cutaneous Larva Migrant (CLM). This study aimed to discover whether hookworm in stray cats (Felis silvestris catus) can cause CLM in humans. We performed a systematic search in Pubmed/Medline and Cochrane published between 2016 and 2021 with no restrictions by language, research country, or type of research design . The results of the analysis showed that the high level of hookworms infection in stray cats could increase the risk of CLM in humans. Based on the study, we could conclude that the high prevalence of hookworm infection in cats plays an important role in the increased risk of zoonoses in humans which in turn could also increase the prevalence of CLM in humans.","PeriodicalId":32666,"journal":{"name":"Folia Medica Indonesiana","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48107652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unusual Choanal Atresia in Children 儿童异常性肛门闭锁

Folia Medica Indonesiana Pub Date : 2022-09-05 DOI: 10.20473/fmi.v58i3.11744

Yunis Sucipta Ibnu, I. Kristyono

引用次数: 0

Bacterial and Antibiogram Profile of Urinary Tract Infection Patients in Tertiary Hospital, Surabaya, Indonesia 印度尼西亚泗水三级医院尿路感染患者的细菌和抗生素谱分析

Folia Medica Indonesiana Pub Date : 2022-09-05 DOI: 10.20473/fmi.v58i3.33186

Mahrumi Dewi Tri Utami, M. Wahyunitisari, N. Mardiana, R. Setiabudi

{"title":"Bacterial and Antibiogram Profile of Urinary Tract Infection Patients in Tertiary Hospital, Surabaya, Indonesia","authors":"Mahrumi Dewi Tri Utami, M. Wahyunitisari, N. Mardiana, R. Setiabudi","doi":"10.20473/fmi.v58i3.33186","DOIUrl":"https://doi.org/10.20473/fmi.v58i3.33186","url":null,"abstract":"Highlights:\u0000\u0000Most urinary tract infections are caused by Gram-negative bacteria with E. coli being the most common bacteria.\u0000Antibiotics with the highest susceptibility for Gram-negative bacteria were ertapenem, meropenem, amikacin, and imipenem.\u0000Antibiotics with the highest susceptibility for Gram-positive bacteria mainly were susceptible to chloramphenicol,streptomycin, vancomycin, rifampin, tigecycline, teicoplanin, and ampicillin.\u0000\u0000 \u0000Abstract:\u0000Urinary tract infection (UTI) is one of the most common bacterial infections. Inappropriate antibiotic use for UTI treatment may lead to antibiotic resistance. This study aimed to provide an updated bacterial and antibiogram profile from urine specimens of patients diagnosed with UTI. This study was a retrospective study using urine culture and antibiotic susceptibility test results obtained from Clinical Microbiology Laboratory in a tertiary general hospital in Surabaya, Indonesia for a two-month period patients. Most aged more than and/or equal to 59 years, in both sexes. Gram-negative bacteria, particularly , was being the most between June to July 2019. There were 215 patients with significant urine culture results of 54.4% from Escherichia coli female bacteria were carbapenem antibiotics and amikacin, while teicoplanin and vancomycin were some antibiotics susceptible to gramcommon bacteria that caused UTI, followed by K. pneumoniae. Some antibiotics with the highest susceptibility to gram-negative positive bacteria. This study result indicated that there was an urge to conduct local antibiogram profile investigation due to the low susceptibilities shown in recent empirical therapy recommendations, such as trimethoprim sulfamethoxazole, fluoroquinolone, nitrofurantoin, and fosfomycin.","PeriodicalId":32666,"journal":{"name":"Folia Medica Indonesiana","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46044866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Vascular Dementia Patients Characteristics With a History of Stroke in a National Brain Center Hospital Jakarta, Indonesia 印尼雅加达国家脑中心医院血管性痴呆患者特征及卒中史

Folia Medica Indonesiana Pub Date : 2022-09-05 DOI: 10.20473/fmi.v58i3.33228

Afifah Kusuma Hanifah, Riezky Valentina Astari, Hikmah Muktamiroh, Arman Yurisaldi Saleh

{"title":"Vascular Dementia Patients Characteristics With a History of Stroke in a National Brain Center Hospital Jakarta, Indonesia","authors":"Afifah Kusuma Hanifah, Riezky Valentina Astari, Hikmah Muktamiroh, Arman Yurisaldi Saleh","doi":"10.20473/fmi.v58i3.33228","DOIUrl":"https://doi.org/10.20473/fmi.v58i3.33228","url":null,"abstract":"Highlights:\u0000\u0000Characteristics of vascular dementia patients with a history of stroke was aimed.\u0000The most characteristics of vascular dementia patients with stroke history are men, post-ischemic stroke, hypertension grade 1, and lesions in the basal ganglia.\u0000\u0000Abstract:\u0000Stroke patients increase each year. Stroke is a cerebrovascular disorder caused by disruption of cerebral blood flow, which could reason vascular lesions within the mind parenchyma to be a threat to significant disorders. One of them is vascular dementia. Each affected person is prone to growing dementia after a stroke in three to five instances. Thisstudy aimed to decide the traits of patients with vascular dementia with a record of stroke. This study used a descriptive retrospective approach with a cross-sectional method. The samples were obtained from the total sampling technique. The sample of the study was vascular dementia patients with a stroke record at the National Brain Center Hospital Prof. Dr. dr. Mahar Mardjono Jakarta in the period of 2020 through the inclusion standards with 191 samples. This study found that the majority of patients were males as many as 129 (67.5%), age group of 55-64 were 67 patients (35.1%), post-ischemic strokes were 164 patients (85.9%), grade 1 hypertension as many as 70 patients (36.6%), and basal ganglia as many as 76 patients (29.23%). Characteristics of vascular dementia patients with the maximum stroke records in men, aged 55-64 years, post-ischemic stroke, grade 1 hypertension, and a majority of the lesions within the basal ganglia.","PeriodicalId":32666,"journal":{"name":"Folia Medica Indonesiana","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45073373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Elevated Serum Transaminase (SGOT/SGPT) and Sepsis in Burn Patients in a Tertiary Hospital, Surabaya, Indonesia 印尼泗水一家三级医院烧伤患者血清转氨酶（SGOT/SGPT）升高与败血症

Folia Medica Indonesiana Pub Date : 2022-06-05 DOI: 10.20473/fmi.v58i2.32865

I. Saputro, L. Zarasade, Rifqi Kurniawan

{"title":"Elevated Serum Transaminase (SGOT/SGPT) and Sepsis in Burn Patients in a Tertiary Hospital, Surabaya, Indonesia","authors":"I. Saputro, L. Zarasade, Rifqi Kurniawan","doi":"10.20473/fmi.v58i2.32865","DOIUrl":"https://doi.org/10.20473/fmi.v58i2.32865","url":null,"abstract":"Highlights:\u0000\u0000There is no correlation between the increase of SGOT and sepsis.\u0000Correlation between the increase of SGPT and sepsis was significant founded.\u0000\u0000 \u0000Abstract:\u0000Burns trigger hypermetabolic stress reactions that cause inflammatory responses. When there is a sustained or increased hypermetabolic reaction, the inflammatory response can be life-threatening, such as sepsis, and significantly impact hepatic metabolic function. After burns, varying degrees of liver injury are usually associated with burn severity. This study determined the correlation between elevated serum transaminases (SGOT/ SGPT) and sepsis in burn patients at a tertiary hospital of Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, from January 1, 2018, to December 31, 2020. This was a descriptive-analytic study with a retrospective cohort design. The data in this study included the demography of burn patients, causes of burns, inhalation trauma, burn severity, increased serum transaminase (SGOT/SGPT), mortality, and sepsis. This study found that the correlation between elevated serum transaminases (SGOT/SGPT) and sepsis was determined using the Spearman-Rho Rank statistical test. Burn patients with sepsis in the hospital were dominated by males (65.2%) and mostly aged 26-55 years (69.6%). The flame was found to be the highest cause of burns (80.4%), burn area above 20% (91.3%), the highest level of severity was major burn (91.3%), and no inhalation trauma (54.3%). In this study, there was an increase in SGOT of 69.6% and SGPT of 78.3%, with a mortality rate of 39.1%, with average inpatient days of 24 days. The correlation test between elevated serum transaminase (SGOT) and sepsis showed an insignificant relationship (p = 0.065, p> 0.05) with a correlation coefficient of 0.200. In contrast, the correlation between elevated serum transaminase (SGPT) and sepsis was significant (p=0.006, p<0.05) with a correlation coefficient of 0.296.","PeriodicalId":32666,"journal":{"name":"Folia Medica Indonesiana","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42106801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

The Combination of NLCR and Enhances the Sepsis-3 Strategy NLCR联合强化脓毒症-3策略

Folia Medica Indonesiana Pub Date : 2022-06-05 DOI: 10.20473/fmi.v58i2.31051

E. Pranggono, Endah Nurul Aini, Uun Sumardi, Yovita Hartranti, A. Sugianli

{"title":"The Combination of NLCR and Enhances the Sepsis-3 Strategy","authors":"E. Pranggono, Endah Nurul Aini, Uun Sumardi, Yovita Hartranti, A. Sugianli","doi":"10.20473/fmi.v58i2.31051","DOIUrl":"https://doi.org/10.20473/fmi.v58i2.31051","url":null,"abstract":"Highlights:\u0000\u0000The combination of NLCR and PLR will improve the ability to distinguish infection rather than noninfection in the emergency setting for early antibiotic prescribing as well as the sepsis-3 strategy.\u0000The diagnostic value of PLR in adult bacterial sepsis patients has never been studied.\u0000\u0000 \u0000Abstract:\u0000According to Sepsis-3, antibiotics should be administered in the first hour of diagnosis of sepsis. Still, there is difficulty in differentiating between bacterial and nonbacterial infections and a lack of a rapid diagnostic tool to distinguish them. This study evaluated the diagnostic value of NLCR and PLR in suspected bacterial sepsis. The diagnostic value of PLR in adult bacterial sepsis patients has never been studied. This study was a retrospective study from the medical record of Dr. Hasan Sadikin Hospital Bandung. All patients at age ≥ 18 years diagnosed with sepsis based on ICD-10 code and qSOFA ≥ 2 were included. We calculated sensitivity, specificity, NPV, PPV, positive LR, and AUC of NLCR and PLR. There were 177 patients included in this study. The sensitivity of NLCR was 69.5%, specificity was 34.7%, NPV was 56.9%, PPV was 47.9%, and LR+ was 1.06, while the sensitivity of PLR was 62.2%, specificity was 38.9%, NPV was 54.4%, PPV was 46.8%, and LR+ was 1.02. We obtained cut-off values for NLCR 11.06, AUC 0.500, PLR 222.41, and AUC 0.497. The low value of AUC NLCR and PLR was due to prior antibiotic use. The combination of NLCR and PLR had higher positive LR (1.16) and specificity (54.7%), and also, according to NLCR, we had the highest sensitivity (69.5%). The combination of NLCR and PLR enhances the sepsis-3 strategy because it can be used as screening tools for bacterial sepsis, and antibiotics can also be administered in the first hour of managing sepsis, particularly in the emergency ward.","PeriodicalId":32666,"journal":{"name":"Folia Medica Indonesiana","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43005646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0