Matrix Science Medica最新文献

{"title":"Assessment of Erythropoiesis-Stimulating Agents for Anemia Treatment among Chronic Kidney Disease Patients: A Descriptive, Retrospective Study","authors":"Zeinab Elamin, S. Badi, B. Yousef","doi":"10.4103/MTSM.MTSM_46_20","DOIUrl":"https://doi.org/10.4103/MTSM.MTSM_46_20","url":null,"abstract":"Background: Renal anemia is a cause of significant morbidity, and to lesser extent mortality in patients with chronic kidney disease (CKD), the leading causes of anemia in CKD primarily are the lack of erythropoietin (EPO) and iron. Thus, effective management is possible using oral and intravenous (IV) iron preparation and genetically engineered erythropoiesis-stimulating agents such as EPO. This study aimed to assess the effect of EPO in the treatment of anemia among hemodialysis (HD) patients. Methods: A descriptive, retrospective hospital-based study was conducted in Elshaheeda Salma Hospital, Khartoum, Sudan. All patients who were anemic or had a history of anemia and undergoing HD during the period (January to June 2018) were recruited. Data were collected using a checklist and analyzed with the Statistical Package for the Social Sciences software. Results: A total of 191 anemic patients were included: 60% of them were males, and more than half of the participants were aged between 41 and 65 years. Clinically, the average duration of the dialysis among participants was 7.7 ± 5 years, and 97% of them had two dialysis sessions per week. Patients were used either IV or subcutaneous injection of EPO. 8000 IU/week were the most prescribed (52.2%) EPO dose. Whereas, only 6% and 18% were taking 100 mg IV and 150 mg oral ferrous sulfate, respectively. Furthermore, 70% of them were taking 5 mg folic acid. Moreover, the mean hemoglobin level among the participants at the end of the study was 10 ± 2.1 g/dl. Conclusion: EPO was effective in treating renal anemia in HD patients. Among the studied patients, 8000 IU/week was the most frequently used dose. The present study highlights significant low adherence to international guidelines in the management of anemia in patients on HD.","PeriodicalId":32519,"journal":{"name":"Matrix Science Medica","volume":"19 5 1","pages":"21 - 24"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85369619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Performing Laryngotracheobronchial Procedure in Coronavirus Disease 2019 Pandemic: A highly Aerosol Generating Event in Clinical Practice","authors":"S. Swain, I. Behera","doi":"10.4103/MTSM.MTSM_38_20","DOIUrl":"https://doi.org/10.4103/MTSM.MTSM_38_20","url":null,"abstract":"The current novel coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).COVID-19 is presenting a significant challenges to the surgical specialties specifically otolaryngologists and head and neck specialties those are dealing with upper airway such as larynx, trachea, and bronchus. The traditional airway procedure like microlaryngeal surgery, tracheostomy, and bronchoscopy are highly aerosol generating surgery often managed by otolaryngologists. The laryngotracheobronchial airway has a high viral density and so it is expected to expel more transmission of the infections in COVID-19 pandemic. This is why the otolaryngologists or laryngologists are more vulnerable medical professional in this dreaded pandemic. Surgeons have high risk for getting the infections during examinations or surgical procedure on the laryngotracheobronchial airway. The surgical interventions should adopt adequate precautions to limit the viral dissemination. Effective management of the suspicious or positive cases of COVID-19 required careful consideration for the safety of the surgeons and associated team members for ensuring the best possible care of the patients. This review article will provide an overview of common methods to limit the viral transmission to the otolaryngologists/surgeons and assisting health care staffs from COVID-19 infections during management of the laryngotracheobronchial airway.","PeriodicalId":32519,"journal":{"name":"Matrix Science Medica","volume":"53 1","pages":"1 - 6"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73704299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aneurysmal bone cyst of head of fibula with transient postoperative neuropraxia of common peroneal nerve","authors":"G. Dharmshaktu, N. Agarwal","doi":"10.4103/mtsm.mtsm_4_21","DOIUrl":"https://doi.org/10.4103/mtsm.mtsm_4_21","url":null,"abstract":"","PeriodicalId":32519,"journal":{"name":"Matrix Science Medica","volume":"119 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73943034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Coronavirus Disease 2019 Pandemic: Meeting the Needs of Vulnerable Population Groups","authors":"S. Shrivastava, P. Shrivastava","doi":"10.4103/MTSM.MTSM_21_20","DOIUrl":"https://doi.org/10.4103/MTSM.MTSM_21_20","url":null,"abstract":"The ongoing Corona Virus Disease-2019 (COVID-19) outbreak has already been given a Pandemic status and also continues to be a public health emergency of international concern. The epidemiological analysis and the trends of mortality clearly suggests that even though, the disease is quite common in all age-groups, the disease has manifested in severe forms among elderly and those people who are having pre-existing medical illnesses. It is the need of the hour to ensure that both these high-risk groups are offered additional attention, without subjecting them to isolation or stigmatization, which decreases their overall probability of access to health care services. Further, it is extremely important to strengthen the risk communication mechanism and take appropriate steps for the relay of timely and trustworthy measures to the entire community, with special attention to the two high-risk groups. In conclusion, as the COVID-19 continues to increase in magnitude and geographical distribution, it is our responsibility to take appropriate steps to improve the wellbeing of community, with an additional support to the high-risk population groups.","PeriodicalId":32519,"journal":{"name":"Matrix Science Medica","volume":"34 1","pages":"25 - 26"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87141245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dermatophytosis and the Role of Enzymes in Pathogenesis","authors":"Falah Obayes Al-Khikani","doi":"10.4103/MTSM.MTSM_23_20","DOIUrl":"https://doi.org/10.4103/MTSM.MTSM_23_20","url":null,"abstract":"","PeriodicalId":32519,"journal":{"name":"Matrix Science Medica","volume":"98 1","pages":"28 - 29"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76131475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Does Frequent Pornography use Adversely Affect Men Sexual Health? A Call for Clinical Investigation","authors":"C. Okechukwu","doi":"10.4103/MTSM.MTSM_20_20","DOIUrl":"https://doi.org/10.4103/MTSM.MTSM_20_20","url":null,"abstract":"","PeriodicalId":32519,"journal":{"name":"Matrix Science Medica","volume":"48 1","pages":"27 - 27"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83632615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Obstetric Outcome in Pregnancies Complicated with Fibroids: A Prospective Observational Study","authors":"Sheema Posh, Suhail Rafiq, Azhar Nisa Quraishi, Saima Wani","doi":"10.4103/MTSM.MTSM_39_20","DOIUrl":"https://doi.org/10.4103/MTSM.MTSM_39_20","url":null,"abstract":"Background: Fibroid is the most frequently recorded benign, monoclonal smooth muscle tumor of the uterus, affecting 20%–60% women of reproductive age. Being remarkably common, fibroids are an important health concern. Fibroids are the most frequent indication for the performance of hysterectomy. The health-care consequences of these tumors are substantial both for the mother as well as the fetus. Objective: The objective is to study the obstetric outcome in pregnancies complicated with uterine fibroids. Materials and Methods: This is an observational study conducted in the Department of Obstetrics and Gynaecology, SKIMS, Soura, Srinagar, from May 2019 to February 2020. A prospective evaluation of a series of 28 antenatal patients presenting with fibroids (>1 cm), who delivered in our hospital was done. Maternal age, parity, size of fibroid, type of fibroid, complications during pregnancy, and mode of delivery were noted. Ultrasonogram was done at booking visit and during subsequent visits to assess the size of the fibroid and degeneration. Obstetric outcome was assessed in terms of abortion, premature delivery, malpresentation, abruption, postpartum hemorrhage (PPH), subinvolution, and puerperal pyrexia. Fetal outcome was assessed in terms of intrauterine growth retardation (IUGR), low-birth weight, and neonatal intensive care unit (NICU) admissions. Results: Majority of the patients belonged to the age group of 25–29 years (35.7%), majority 19 (67.9%) were multigravida, most 17 (60.7%) of the fibroids were >3 cm in size. There were 2 (7.1%) cases of miscarriage, 6 (21.4%) cases of malpresentation, abruption in 2 (7.1%) cases, 3 (10.7%) had PPH and only 1 (3.6%) needed blood transfusion. A total of 18 (69.2%) patients delivered by lower segment caesarean section and 8 (30.7%) had vaginal delivery. Of 26 babies, 6 (23.1%) had low-birthweight, 2 (7.7%) were IUGR and there were 2 (7.7%) NICU admissions. Conclusion: Even though most of the fibroids in pregnancy are asymptomatic but such pregnancies should be considered as high risk pregnancies. Hence, pregnancy has to be cautiously screened in the antenatal period, through regular follow-up, to detect any adverse obstetric complications thereby improving fetomaternal outcome. Our study also suggests that reduction in fibroid size pre-pregnancy may play a vital role in preventing maternal and fetal complications which became inevitable once pregnancy reaches advanced gestation.","PeriodicalId":32519,"journal":{"name":"Matrix Science Medica","volume":"12 1","pages":"12 - 16"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89049957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Significance of surveillance in COVID-19 pandemic and adoption of innovative strategies for its strengthening","authors":"S. Shrivastava, P. Shrivastava","doi":"10.4103/MTSM.MTSM_19_20","DOIUrl":"https://doi.org/10.4103/MTSM.MTSM_19_20","url":null,"abstract":"The Corona Virus Disease 2019 (COVID-19) pandemic has spread rapidly across the globe and has impacted each and every community directly or indirectly. Amidst the various components which require strengthening for the successful containment, surveillance is a critical aspect and it significantly aids in reducing the spread of the infection by empowering the public health authorities with the right information. Acknowledging the importance of surveillance, the need of the hour is to strengthen surveillance through adoption of digital technologies which aid in the rapid reporting & data analysis, and even expand in regions with lesser number of cases. In conclusion, surveillance is an integral component of the preparedness and emergency response against the COVID-19 pandemic. It is the need of the hour to adopt innovative strategies to ensure that surveillance is strengthened and we succeed in obtaining comprehensive information about the disease and its spread in the community.","PeriodicalId":32519,"journal":{"name":"Matrix Science Medica","volume":"35 1","pages":"134 - 135"},"PeriodicalIF":0.0,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78359433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Coronavirus disease-2019 infection among health-care professionals: predisposing factors and preventive strategies","authors":"S. Shrivastava, P. Shrivastava","doi":"10.4103/MTSM.MTSM_13_20","DOIUrl":"https://doi.org/10.4103/MTSM.MTSM_13_20","url":null,"abstract":"The Corona Virus Disease-2019 (COVID-19) infection has been reported among all, regardless of their region, nation, ethnicity, religion, age-group, gender, socioeconomic class and work profile. Against this novel viral infection, the health care workers are the only group of professionals who are working right from the day one, when the first case was reported and nothing was known about the infection. It is extremely important to protect health care professionals from infection both in the hospital and community settings. A wide range of factors has been attributed to the acquisition of infection among health workers in hospital settings. In conclusion, the role of health care professionals in the containment of the COVID-19 pandemic is of utmost importance and thus it is crucial to get more epidemiological insights about the infection and thus ensure their safety and well-being in the workplace.","PeriodicalId":32519,"journal":{"name":"Matrix Science Medica","volume":"15 1","pages":"130 - 131"},"PeriodicalIF":0.0,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88813658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adherence of health-care providers to hypertension management guidelines in Khartoum, Sudan, 2020","authors":"A. Saeed, Lamees Abdelrhman, L. Saad, Marah Omran, Inas Osman","doi":"10.4103/MTSM.MTSM_33_20","DOIUrl":"https://doi.org/10.4103/MTSM.MTSM_33_20","url":null,"abstract":"Introduction: Hypertension has the highest prevalence among the major non-communicable diseases in Sudan (prevalence 27.6%) due to high amount of salt intake in foods, lack of exercise, obesity, stress, smoking, and increase in age. Different guidelines have been proposed from time to time to increase the number of patients with controlled blood pressure. It is a well-established fact that poor disease control is largely related to the poor patient compliance to medical advice and medications. However, the other important aspect of the same problem is the physician's adherence to evidence-based management of hypertension, but, unfortunately, this has not been studied adequately. Objective: The objective is to investigate adherence practices of health care providers to the use of clinical practice guidelines in Khartoum, Sudan. Materials and Methods: An observational cross-sectional study was carried out from February to April 2020 among health-care providers which include prescribing doctors and community pharmacists in Khartoum locality. Data were collected using electronic delivery validated questionnaire. Results: A total of 200 health-care professionals (HCPs) voluntary participated, 51% were pharmacists, while 49% were prescribing doctors. As overall 86.125% of participated health-care provider aware about hypertension as a health problem as a mean of their correct responses. In the area of measurement and management of a new case of hypertension, the mean of the responses (mean of correct answers) which follow guidelines was 55.75%. In the area of selection of anti-hypertensive treatment in comorbid conditions the mean responses of correct responses was 58.88%. Conclusions: Our study observed that the majority of HCP adhere to guidelines for hypertension in Khartoum locality. The study showed a lack of knowledge among HCPs in managing hypertension in patients with the comorbid condition.","PeriodicalId":32519,"journal":{"name":"Matrix Science Medica","volume":"15 1","pages":"116 - 120"},"PeriodicalIF":0.0,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83916989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}