Matrix Science Medica最新文献

{"title":"The Ethicality of Genetically Modified Organisms: Is the Use and Proliferation of Genetically Modified Organisms Ethical?","authors":"Jason Lai","doi":"10.4103/mtsm.mtsm_22_23","DOIUrl":"https://doi.org/10.4103/mtsm.mtsm_22_23","url":null,"abstract":"This paper examines the ethics, economic effects, and global marketing and communication styles of genetically modified organisms (GMOs). While GMOs have sparked controversial debates since their 1994 introduction, evidence from this paper suggests that they offer significant environmental, health, and economic benefits. Analysis in this paper also shows that effective communication and marketing strategies for GMOs are vital to bridge the gap between scientific consensus and false public perception, ensuring that GMOs are used ethically and sustainably.","PeriodicalId":32519,"journal":{"name":"Matrix Science Medica","volume":"17 15‐16","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141849233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Variations in Plasma Glucose, Testosterone, and Tumor Necrosis Factor-alpha in Relationship with Polycystic Ovary Syndrome and Viral Seromarkers in Infertile Women: A Case–Control Observational Study","authors":"M. Olaniyan, Tolu Olaniyan, Evangeline Ijeoma Umeche","doi":"10.4103/mtsm.mtsm_8_23","DOIUrl":"https://doi.org/10.4103/mtsm.mtsm_8_23","url":null,"abstract":"\u0000 \u0000 Polycystic ovary syndrome (PCOS) is a common cause of infertility in Nigeria which is associated with insulin resistance. Insulin resistance may be induced by elevated inflammatory cytokines, androgen excess (testosterone), and irregular menstruation or anovulation.\u0000 \u0000 \u0000 \u0000 This work was designed to determine possible variations in plasma glucose, testosterone, and tumor necrosis factor-alpha (TNFα) in relationship with PCOS and viral seromarkers in infertile women.\u0000 \u0000 \u0000 \u0000 Two hundred and fourteen (214) primary infertility women with PCOS aged 37 ± 4.93 years diagnosed through ultrasound were recruited as test subjects while one hundred (100) age-matched primary infertility women without PCOS were recruited as control. All subjects were negative to Giemsa thick blood film staining for the detection of Plasmodium and Ziehl–Neelsen staining for the detection of acid–fast bacilli. HIVp24 antigen and antibody, plasma testosterone, antibody to hepatitis C virus (anti-HCV), and envelope antigen to hepatitis B Virus (HBeAg) were determined in the subjects by enzyme-linked immunosorbent assay while blood glucose was measured spectrophotometrically.\u0000 \u0000 \u0000 \u0000 The results obtained showed a higher frequency of 0.93% (2) HIVP24antigen-antibody, 6.5% (17) anti-HCV, 14.5% (31) HBeAg, and 0.5% (1) HIVP24 + HBeAg (except for HIVP24 antigen and antibody) in PCOS women than the frequency of viral seromarkers of 1% (1) HIVP24 antigen and antibody, 6% (6) anti-HCV, 8% (8) HBeAg, and 0% (0) HIVP24 + HBeAg in non-PCOS control women. There was a significant association between PCOS and expression of viral seromarkers; there was a significantly higher fasting plasma glucose and testosterone level in all PCOS women with or without viral seromarkers (P < 0.05). There was a significantly higher plasma TNFα in PCOS women that expressed viral seromarkers than in PCOS women who do not express any of the viral seromarkers (P < 0.05). There was a significantly higher plasma TNFα in PCOS and non-PCOS women although more in PCOS women that expressed viral seromarkers than in women without any viral seromarker (P < 0.05).\u0000 \u0000 \u0000 \u0000 PCOS may be characterized by elevated plasma fasting glucose, testosterone, and expression of viral seromarkers while viral infection could also trigger higher plasma TNFα in PCOS women than in non-PCOS women infected with viral agent.\u0000","PeriodicalId":32519,"journal":{"name":"Matrix Science Medica","volume":"2 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141849329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Burden of Respiratory Disease in Childhood","authors":"H. Al-Hasnawy, R. Hasani, Jwan Ahmed Al-Hamawandi, Raghdah Maytham Hameed","doi":"10.4103/mtsm.mtsm_15_23","DOIUrl":"https://doi.org/10.4103/mtsm.mtsm_15_23","url":null,"abstract":"Respiratory disease is an acute or chronic illness affecting the airways and other structures of the lungs. Asthma, bronchitis, pneumonia, pulmonary hypertension, allergic rhinitis, and sinusitis are the most common respiratory diseases which affect children. Respiratory disease strains health-care resources due to the doctor and hospital visits and the cost of treatment. Further, it can significantly impact on child’s health and is a fundamental cause of missed school days, limitations of activities, and social interaction. The prevalence of respiratory diseases in children increased significantly over the last decade, possibly because of different exposure to indoor and outdoor pollution, lifestyle, and respiratory infection. Certain risk factors appear to predispose children to develop respiratory disease, including genetic predisposition and exposure to environmental triggers. This article discusses the burden, prevalence, risk factors, and treatment associated with a pediatric respiratory disorder.","PeriodicalId":32519,"journal":{"name":"Matrix Science Medica","volume":"18 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141848698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the Impact of Lead on Health and Strategies to Prevent the Adverse Consequences","authors":"S. Shrivastava, P. Shrivastava","doi":"10.4103/mtsm.mtsm_26_22","DOIUrl":"https://doi.org/10.4103/mtsm.mtsm_26_22","url":null,"abstract":"Lead is one of the ten chemicals of major public health concern, and has been linked to environmental degradation and significant deterioration of human health. Multiple age-group-specific harmful effects in children, pregnant women, and adults have been reported secondary to lead exposure. Even though lead-associated adverse effects have been recognized in different parts of the world, the key barrier is the least priority assigned to it by public health officials worldwide. To conclude, owing to both short- and long-term effects of lead in different age groups, it is high time that global policymakers should prioritize lead poisoning and take appropriate measures to effectively deal with the public health menace of lead.","PeriodicalId":32519,"journal":{"name":"Matrix Science Medica","volume":"34 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141847013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Review of the Impact of Patent Medicine Vendors in Driving Community Tuberculosis Case Finding in the COVID-19 Pandemic in Nigeria","authors":"A. Ajogwu, Onwubiko Iheanyichukwu Samuel, Nnanyelugo Longinus Ochike, Uzoma Chidinma Ajegbo, Chinedu Paschal Maduka","doi":"10.4103/mtsm.mtsm_23_23","DOIUrl":"https://doi.org/10.4103/mtsm.mtsm_23_23","url":null,"abstract":"This review elucidates the pivotal role of patent medicine vendors (PMVs) in advancing community tuberculosis (TB) case finding in Nigeria, amidst the disruptions caused by the COVID-19 pandemic. By synthesizing insights from in-depth analyses, the article explores PMVs’ adaptability, knowledge, community trust, and contributions to TB case-finding efforts during this unprecedented period. The study reveals that PMVs, despite varying levels of knowledge on TB symptoms and diagnosis, have demonstrated significant resilience and adaptability, incorporating innovative approaches such as virtual consultations to sustain case finding during the pandemic. Their substantial involvement in health-care delivery, especially in underserved areas, and the evident community trust in their services, positions them as crucial health-care resources in regions with limited access to formal health-care services. However, the review also uncovers challenges, including the need for quality assurance and adherence to guidelines, and emphasizes the importance of tailored training programs to bridge knowledge gaps and empower PMVs to contribute more effectively to early TB detection. The study underscores the potential of PMVs to bridge gaps in health-care access and advocates for strengthened collaborations between PMVs and formal health-care systems to optimize their role in identifying and referring suspected TB cases effectively. In conclusion, the article highlights the transformative contribution of PMVs in TB case finding in Nigeria, during the COVID-19 pandemic and proposes recommendations to enhance their impact through capacity strengthening, integration into formal health-care systems, and leveraging innovative technologies. The findings suggest that harnessing the potential of PMVs can significantly contribute to controlling TB and improving public health outcomes, especially in anticipation of further outbreaks, by fostering a more community-centered approach to case finding.","PeriodicalId":32519,"journal":{"name":"Matrix Science Medica","volume":"59 37","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140795778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgical Treatment of Tinnitus","authors":"S. Swain, Debasmita Dubey","doi":"10.4103/mtsm.mtsm_5_23","DOIUrl":"https://doi.org/10.4103/mtsm.mtsm_5_23","url":null,"abstract":"Tinnitus is the perception of sound in the absence of an external sound and often results in a disorder of the somatosensory system or the auditory system. Tinnitus is a common clinical symptom that can be debilitating. The risk factors for tinnitus include hearing loss, ototoxicity, head trauma, and depression. Tinnitus is only a symptom that might be the result of different underlying pathologies. The exact treatment of tinnitus has often several options because of its etiological heterogeneity. Although much progress has been made, tinnitus is still considered a scientific and clinical enigma. The search for effective tinnitus treatment faces considerable challenges. Despite numerous trials, no drugs have been approved by the Food and Drug Administration for the treatment of tinnitus. There are different types of treatment for tinnitus that have been tested in properly controlled trials. These treatment options include pharmacological, acoustic-physical, psychological, and surgical. In clinical practice, no pharmacological agent has been shown to have a lasting effect on the presence or severity of tinnitus. Surgery has a small but definite role in the treatment of tinnitus. Surgical intervention is often helpful in relieving most of the objective tinnitus. This review article discusses the epidemiology, indications, and different surgical approaches for tinnitus.","PeriodicalId":32519,"journal":{"name":"Matrix Science Medica","volume":"523 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140787857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spinal Cord Stroke in Endocarditis with Owl Eye Radiological Presentation","authors":"Tariq Janjua, Matt M. Manganaro, L. Moscote-Salazar","doi":"10.4103/mtsm.mtsm_16_22","DOIUrl":"https://doi.org/10.4103/mtsm.mtsm_16_22","url":null,"abstract":"","PeriodicalId":32519,"journal":{"name":"Matrix Science Medica","volume":"29 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140796726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Distribution of Parasitic Infections among Pupils in Kwara State, Nigeria","authors":"R. Aliyu, P. O. Omosigho, M. Olaniyan","doi":"10.4103/mtsm.mtsm_17_23","DOIUrl":"https://doi.org/10.4103/mtsm.mtsm_17_23","url":null,"abstract":"\u0000 \u0000 Parasitic infections pose a significant health burden among school-age children in Nigeria.\u0000 \u0000 \u0000 \u0000 This study aimed to investigate the distribution of parasitic infections among pupils in Kwara State, Nigeria.\u0000 \u0000 \u0000 \u0000 A total of 638 pupils from various primary schools in Kwara Central, Kwara South, and Kwara North senatorial districts were included in the study. Stool, blood, and urine samples were collected from each participant, and appropriate preservation methods were employed. Parasite identification was carried out using microscopy, staining techniques, and concentration methods described in previous studies.\u0000 \u0000 \u0000 \u0000 The results revealed an overall prevalence of 19.4% among the pupils, with 80.6% found to be uninfected. The most common parasitic infections were Ascaris lumbricoides (55.6%), Schistosoma mansoni (11.2%), Plasmodium (10.5%), Entamoeba histolytica (8.9%), Hookworm (8.1%), Fasciola gigantica (4.0%), and Schistosoma haematobium (1.6%). Further analysis focused on the age distribution of parasitic infections. Among pupils aged 1–5 years, Plasmodium infection had a prevalence of 23.1%. In the 6–10 years age group, A. lumbricoides (59.4%), S. mansoni (74%), E. histolytica (45.5%), Hookworm (30.0%), F. gigantica (20%), and Plasmodium (61.5%) were prevalent. Among pupils aged 11–15 years, A. lumbricoides (40.6%), S. mansoni (28.6%), E. histolytica (54.5%), Hookworm (70.0%), F. gigantica (60.0%), Plasmodium (15.4%), and S. haematobium (1.6%) were observed. Pupils aged 16–20 years showed a lower prevalence of parasitic infections, with F. gigantica (20%) being the only detected parasite.\u0000 \u0000 \u0000 \u0000 The findings highlight the varying distribution of parasitic infections among different age groups, emphasizing the need for age-specific interventions. The high prevalence of certain parasites, such as A. lumbricoides, S. mansoni, and Plasmodium, indicates the importance of implementing targeted deworming programs, improved sanitation, hygiene practices, and malaria prevention strategies. These measures can effectively reduce the burden of parasitic infections and promote the health and well-being of pupils in Kwara State, Nigeria.\u0000","PeriodicalId":32519,"journal":{"name":"Matrix Science Medica","volume":"58 15","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140795397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application of CRISPR/Cas12a for SARS-CoV-2 Nucleic Acid Detection","authors":"Xin You, Rongrong He, Suhui Li, Yibo Zhang","doi":"10.4103/mtsm.mtsm_14_23","DOIUrl":"https://doi.org/10.4103/mtsm.mtsm_14_23","url":null,"abstract":"SARS-CoV-2 spans 3 years, and although the virus has been adjusted from \"Category B, Tube A\" to \"Category B, Tube B\" it is still present in the environment, causing widespread epidemic infections and great impact on human health and the environment. Currently, there are various nucleic acid detection methods for this virus, and CRISPR methods are widely used to construct biosensors for accurate and rapid specific detection of nucleic acid sequences due to their powerful gene-editing capabilities. In this article, we introduce the application of different forms of sensors such as fluorescent paper strips built with CRISPR/Cas12a for SARS-CoV-2 nucleic acid detection.","PeriodicalId":32519,"journal":{"name":"Matrix Science Medica","volume":"93 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140760865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oral cavity manifestations in coronavirus disease 2019 patients: A COVID hospital-based study","authors":"S. Swain, Prasenjit Baliarsingh, Debasmita Dubey","doi":"10.4103/mtsm.mtsm_16_23","DOIUrl":"https://doi.org/10.4103/mtsm.mtsm_16_23","url":null,"abstract":"Background: Coronavirus disease 2019 (COVID-19) is an acute respiratory disease caused by novel severe acute respiratory syndrome coronavirus 2. COVID-19 infection presents with mild flu-like symptoms to severe respiratory illness, even respiratory failure. Oral cavity lesions are currently documented in the COVID-19 infections, which increases the morbidity of the patients. Objective: The aim of this study is to evaluate the different types of the oral cavity lesions in COVID-19 patient, including its symptoms and signs. Materials and Methods: This is a prospective observational study. COVID-19 patients were evaluated for oral cavity manifestations. The age ranges from 18 years to 65 years. All these patients underwent detailed examinations of the oral cavity and oropharynx with the help of headlight, along with wearing personal protective equipment. Results: Fifty-six COVID-19 patients showed oral cavity manifestations during their treatment period. The most common clinical entity in this study was gustatory disturbance (26.78%), followed by oral mucositis (14.28%), glossitis (12.50%), and ulcers (8.92%) in the oral cavity of the COVID-19 patients. Conclusion: COVID-19 infection significantly affects the oral cavity and salivary glands. Clinicians should keep in mind different lesions in the oral cavity and taste disturbances of COVID-19 patients, which will help the early diagnosis, treatment and avoid the morbidity of the patient.","PeriodicalId":32519,"journal":{"name":"Matrix Science Medica","volume":"161 1","pages":"109 - 113"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139326105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}